Click here to switch to the map view.

The map label for this gene is lytG [H]

Identifier: 116872472

GI number: 116872472

Start: 1073499

End: 1075820

Strand: Direct

Name: lytG [H]

Synonym: lwe1056

Alternate gene names: 116872472

Gene position: 1073499-1075820 (Clockwise)

Preceding gene: 116872471

Following gene: 116872473

Centisome position: 38.15

GC content: 32.95

Gene sequence:

>2322_bases
ATGATAAATAAAAAGTGGATGAAAATTGTAATGATACCAATGTTAGTTGTTCCAATGTACGGAGTGACAACTCTAGGTAG
CCAATTACAAGATTCATTAACTGGAAAAAATTCCTTTGTTAAAGACGTAGAAGCTGCTACAACAGAGCAACAGACGTTTA
TCAACAAACTTGCACCCGCAGCTCAGGCATCTCAAGAAAAATATAAACTTCTGTCTAGTATAACTTTAGCTCAAGGGATT
CTAGAATCTAATTGGGGAAAAAGTGGACTTGCAACAAAAGGTAATAATTTATTCGGAATAAAAGGAAAATACAATAACCA
ATCTGTAATTATGCAAACTTCTGAATATGTTAATGGACAGTGGATAAAAGTTGATGCAGAATTTCGTAAATATCCAAGTT
GGAATGAATCAGTTACTGACCATACCTTATTACTTGTAAATGGTACTTCTTGGAATAGAGACTTATATAAAAAAGTTGTT
AATGCAACAGATTATAAAGTAGCTGCAAATGAACTTCAAAAAGCTGGATATGCTACAGATCCAAATTATGCTTCCAGTTT
AATCCGAGTAATTGAGACTTATGATTTAGCAAAATACGATGTTTTATATGATAAAATTCTCACTCAAAAATCTATCTCAG
AGAAAGCCACTGTGACAAATCCAACTGGGAACGGTATATGGTCTTTACCCTATAAAGTTAAGGGAGTAGCGTCTGTTGGT
CCAGCTAGTGGATATGCTAATAAAGATATTGATTTGATTTCTGTGGCTACTACAAAAAGAGGAACTTATTATCAATTTAA
ATATAATGGTAAAGTGATTGGCTGGCTTGATGGAAAGGCACTAACTATTTATGATAAAGTAAATTATGACAAGTCTTATG
TAGGAAGAGCGAAAATATCAAGTCCAACTAGTAATGGTATTTGGTCTAAACCATATAACATATATGGACGTGAATTTGTG
GCAAATGCAACCACATATGCACAACAAGAAATAAAACTTTTACGTGAAGCGCAAACTGCAAAAGGCACATATTATCAATT
TAGTATCAATAATAAAATAATTGGTTGGATTGATAAAAGAGCTTTAACAATTTATCCTTATGATTCCATTATCTCAAGTA
AAAATGTGAATCTAGCTGGGCAAATTACTAACCCAACTGGAAATGGTATTTGGTCTAAGGCATACAAGTTAGAGGGCACA
ACTTCTGTTGCACCAGCTTCTAAATATGCCAATCAGGATGTTAATATTAATCAACAAATTGAAACTCAACATGGTAGTTA
TTATAATATTAGTATCAATGGTAAAAATATCGGTTGGTTAGATCAAAAAGCTCTTACACTTTATGATGTAGAAGAATATA
ATAAAGCAGTTTCATTTGATGGTACCATTAAAAATGTTAAGAGTAACACAATATGGACTAAGCCTTATCGAACAGTTGGC
ACAAAATCAGTTGGTCCAGCCGAAGCATATTTAAACAAAGATGTTCAAATAATTCGCGAAGCCAAAACACCAAAAGGTAC
TTACTATCAATTTAAATCAGCTGGTAAAGTGATTGGTTGGTTGGATCAAAAAGCTTTCGAAATATATGACAACATTCTTT
ATAATAAAGTTGTCAATATGGAGGCTGTAGTTGAGAATGTAACTGGTAACGCTGTTTGGTCAGCTCCATATAAGAGTAAA
GGTGTCCAAGGGATAACTACGGCAAACACATACAAAGATAAAACAGTTAAATTAACTCGAGAAGCTCAGACAAGTAGAGG
AACGTATTATGAGTTTAGCTATAACGGCAAAGTGATAGGCTGGTTAGATAAGAAAGCATTTAAATTCTATAATACATTAG
AATATGATGAAGTTTACAATAGAGATGCTATAATTACTAATGTAACCGGAAATACAGTTTGGACATTACCATATCAAATC
TATGGCACTAAAGCTGTTAATCCTGCAGCAACATATAAAAACCAACAAGCAAGAATTACAAGAAAAGCTAAAACCGAAAG
GGGTATCTACTACCAATTTAGCATTAATGGAAAAAATATCGGTTGGCTAGATGAGAAAGCATTTGATGTTTATGATGAAA
TTGAGTATAACAAAAACATTAAGTTAACTGGTATACTAAGTAATGCTTCAGGAAATGCTATTTGGTCAGAACCTTACCGA
GTTATTGGAACGAAAAATGTCGGGCAAGCAACATCTTATGCAAATAAAACTGTACAATTAGTGAAAGAAGCTAAGACAAC
ACGTTCCACTTATTATCAAATGAGTATTAATGGAAAAGTAATTGGTTGGGTAGATAAACGCGCGTTCACAAATGTTAAAT
AA

Upstream 100 bases:

>100_bases
ATTGAAATCATCTGTTTTGTAATACTTCTGTAACTTACTATAGCATAAAGTTTGGTAAAATATAGGACAGTAATATAATT
TAAGGAGTGGTTTGAAAATA

Downstream 100 bases:

>100_bases
ATGAGAAGAAGTAGAGTATCTATTTATAGGTATTTCTACTTCTTTTTTTTCAATGTTGAAAATAAGTATTAAATAAGATA
TGCTGTATATATTGATTTTT

Product: N-acetylmuramoyl-L-alanine amidase

Products: NA

Alternate protein names: Autolysin lytG; Exo-beta-N-acetylglucosaminidase lytG; Peptidoglycan hydrolase lytG [H]

Number of amino acids: Translated: 773; Mature: 773

Protein sequence:

>773_residues
MINKKWMKIVMIPMLVVPMYGVTTLGSQLQDSLTGKNSFVKDVEAATTEQQTFINKLAPAAQASQEKYKLLSSITLAQGI
LESNWGKSGLATKGNNLFGIKGKYNNQSVIMQTSEYVNGQWIKVDAEFRKYPSWNESVTDHTLLLVNGTSWNRDLYKKVV
NATDYKVAANELQKAGYATDPNYASSLIRVIETYDLAKYDVLYDKILTQKSISEKATVTNPTGNGIWSLPYKVKGVASVG
PASGYANKDIDLISVATTKRGTYYQFKYNGKVIGWLDGKALTIYDKVNYDKSYVGRAKISSPTSNGIWSKPYNIYGREFV
ANATTYAQQEIKLLREAQTAKGTYYQFSINNKIIGWIDKRALTIYPYDSIISSKNVNLAGQITNPTGNGIWSKAYKLEGT
TSVAPASKYANQDVNINQQIETQHGSYYNISINGKNIGWLDQKALTLYDVEEYNKAVSFDGTIKNVKSNTIWTKPYRTVG
TKSVGPAEAYLNKDVQIIREAKTPKGTYYQFKSAGKVIGWLDQKAFEIYDNILYNKVVNMEAVVENVTGNAVWSAPYKSK
GVQGITTANTYKDKTVKLTREAQTSRGTYYEFSYNGKVIGWLDKKAFKFYNTLEYDEVYNRDAIITNVTGNTVWTLPYQI
YGTKAVNPAATYKNQQARITRKAKTERGIYYQFSINGKNIGWLDEKAFDVYDEIEYNKNIKLTGILSNASGNAIWSEPYR
VIGTKNVGQATSYANKTVQLVKEAKTTRSTYYQMSINGKVIGWVDKRAFTNVK

Sequences:

>Translated_773_residues
MINKKWMKIVMIPMLVVPMYGVTTLGSQLQDSLTGKNSFVKDVEAATTEQQTFINKLAPAAQASQEKYKLLSSITLAQGI
LESNWGKSGLATKGNNLFGIKGKYNNQSVIMQTSEYVNGQWIKVDAEFRKYPSWNESVTDHTLLLVNGTSWNRDLYKKVV
NATDYKVAANELQKAGYATDPNYASSLIRVIETYDLAKYDVLYDKILTQKSISEKATVTNPTGNGIWSLPYKVKGVASVG
PASGYANKDIDLISVATTKRGTYYQFKYNGKVIGWLDGKALTIYDKVNYDKSYVGRAKISSPTSNGIWSKPYNIYGREFV
ANATTYAQQEIKLLREAQTAKGTYYQFSINNKIIGWIDKRALTIYPYDSIISSKNVNLAGQITNPTGNGIWSKAYKLEGT
TSVAPASKYANQDVNINQQIETQHGSYYNISINGKNIGWLDQKALTLYDVEEYNKAVSFDGTIKNVKSNTIWTKPYRTVG
TKSVGPAEAYLNKDVQIIREAKTPKGTYYQFKSAGKVIGWLDQKAFEIYDNILYNKVVNMEAVVENVTGNAVWSAPYKSK
GVQGITTANTYKDKTVKLTREAQTSRGTYYEFSYNGKVIGWLDKKAFKFYNTLEYDEVYNRDAIITNVTGNTVWTLPYQI
YGTKAVNPAATYKNQQARITRKAKTERGIYYQFSINGKNIGWLDEKAFDVYDEIEYNKNIKLTGILSNASGNAIWSEPYR
VIGTKNVGQATSYANKTVQLVKEAKTTRSTYYQMSINGKVIGWVDKRAFTNVK
>Mature_773_residues
MINKKWMKIVMIPMLVVPMYGVTTLGSQLQDSLTGKNSFVKDVEAATTEQQTFINKLAPAAQASQEKYKLLSSITLAQGI
LESNWGKSGLATKGNNLFGIKGKYNNQSVIMQTSEYVNGQWIKVDAEFRKYPSWNESVTDHTLLLVNGTSWNRDLYKKVV
NATDYKVAANELQKAGYATDPNYASSLIRVIETYDLAKYDVLYDKILTQKSISEKATVTNPTGNGIWSLPYKVKGVASVG
PASGYANKDIDLISVATTKRGTYYQFKYNGKVIGWLDGKALTIYDKVNYDKSYVGRAKISSPTSNGIWSKPYNIYGREFV
ANATTYAQQEIKLLREAQTAKGTYYQFSINNKIIGWIDKRALTIYPYDSIISSKNVNLAGQITNPTGNGIWSKAYKLEGT
TSVAPASKYANQDVNINQQIETQHGSYYNISINGKNIGWLDQKALTLYDVEEYNKAVSFDGTIKNVKSNTIWTKPYRTVG
TKSVGPAEAYLNKDVQIIREAKTPKGTYYQFKSAGKVIGWLDQKAFEIYDNILYNKVVNMEAVVENVTGNAVWSAPYKSK
GVQGITTANTYKDKTVKLTREAQTSRGTYYEFSYNGKVIGWLDKKAFKFYNTLEYDEVYNRDAIITNVTGNTVWTLPYQI
YGTKAVNPAATYKNQQARITRKAKTERGIYYQFSINGKNIGWLDEKAFDVYDEIEYNKNIKLTGILSNASGNAIWSEPYR
VIGTKNVGQATSYANKTVQLVKEAKTTRSTYYQMSINGKVIGWVDKRAFTNVK

Specific function: Is the major glucosaminidase responsible for peptidoglycan structural determination during vegetative growth. Acts processively from the ends of the glycan strands. Also plays a role in motility, chemotaxis and cell division [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted, cell wall [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 73 family [H]

Homologues:

Organism=Escherichia coli, GI1787321, Length=150, Percent_Identity=34, Blast_Score=80, Evalue=6e-16,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000423
- InterPro:   IPR013338
- InterPro:   IPR002901 [H]

Pfam domain/function: PF01832 Glucosaminidase [H]

EC number: 3.2.1.- [C]

Molecular weight: Translated: 86790; Mature: 86790

Theoretical pI: Translated: 9.93; Mature: 9.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINKKWMKIVMIPMLVVPMYGVTTLGSQLQDSLTGKNSFVKDVEAATTEQQTFINKLAPA
CCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCH
AQASQEKYKLLSSITLAQGILESNWGKSGLATKGNNLFGIKGKYNNQSVIMQTSEYVNGQ
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCEEEEEEHHCCCCE
WIKVDAEFRKYPSWNESVTDHTLLLVNGTSWNRDLYKKVVNATDYKVAANELQKAGYATD
EEEEEHHHHCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCCCHHHHHHHHCCCCCC
PNYASSLIRVIETYDLAKYDVLYDKILTQKSISEKATVTNPTGNGIWSLPYKVKGVASVG
CHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEECCCCCCEEECCEEEEEEEECC
PASGYANKDIDLISVATTKRGTYYQFKYNGKVIGWLDGKALTIYDKVNYDKSYVGRAKIS
CCCCCCCCCCEEEEEEECCCCEEEEEEECCEEEEEECCCEEEEEEECCCCHHHCCCEEEC
SPTSNGIWSKPYNIYGREFVANATTYAQQEIKLLREAQTAKGTYYQFSINNKIIGWIDKR
CCCCCCCCCCCCCCCCHHHHHCHHHHHHHHHHHHHHHHHCCCEEEEEEECCEEEEEECCC
ALTIYPYDSIISSKNVNLAGQITNPTGNGIWSKAYKLEGTTSVAPASKYANQDVNINQQI
EEEEECCHHHHCCCCCEEEEEEECCCCCCCCCEEEEECCCCCCCCCHHHCCCCCCCCCEE
ETQHGSYYNISINGKNIGWLDQKALTLYDVEEYNKAVSFDGTIKNVKSNTIWTKPYRTVG
ECCCCCEEEEEECCCCCCCCCCCCEEEEEHHHHCCEEECCCCCCCCCCCCEEECCCCCCC
TKSVGPAEAYLNKDVQIIREAKTPKGTYYQFKSAGKVIGWLDQKAFEIYDNILYNKVVNM
CCCCCCHHHHHCCCHHHHHHCCCCCCCEEEECCCCCEEEHHHHHHHHHHHHHHHHHHCCH
EAVVENVTGNAVWSAPYKSKGVQGITTANTYKDKTVKLTREAQTSRGTYYEFSYNGKVIG
HHHHHCCCCCEEECCCCCCCCCCCEEECCCCCCCEEEEEEHHCCCCCCEEEEEECCEEEE
WLDKKAFKFYNTLEYDEVYNRDAIITNVTGNTVWTLPYQIYGTKAVNPAATYKNQQARIT
EECHHHHHHHCCCCHHHHCCCCEEEEECCCCEEEEEEEEEEECCCCCHHHHCCCCHHHHH
RKAKTERGIYYQFSINGKNIGWLDEKAFDVYDEIEYNKNIKLTGILSNASGNAIWSEPYR
HHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHHHCCCCCEEEEEEEECCCCCCEECCCEE
VIGTKNVGQATSYANKTVQLVKEAKTTRSTYYQMSINGKVIGWVDKRAFTNVK
EEECCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCEEEEEECCCCCCCCC
>Mature Secondary Structure
MINKKWMKIVMIPMLVVPMYGVTTLGSQLQDSLTGKNSFVKDVEAATTEQQTFINKLAPA
CCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCH
AQASQEKYKLLSSITLAQGILESNWGKSGLATKGNNLFGIKGKYNNQSVIMQTSEYVNGQ
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCEEEEEEHHCCCCE
WIKVDAEFRKYPSWNESVTDHTLLLVNGTSWNRDLYKKVVNATDYKVAANELQKAGYATD
EEEEEHHHHCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCCCHHHHHHHHCCCCCC
PNYASSLIRVIETYDLAKYDVLYDKILTQKSISEKATVTNPTGNGIWSLPYKVKGVASVG
CHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEECCCCCCEEECCEEEEEEEECC
PASGYANKDIDLISVATTKRGTYYQFKYNGKVIGWLDGKALTIYDKVNYDKSYVGRAKIS
CCCCCCCCCCEEEEEEECCCCEEEEEEECCEEEEEECCCEEEEEEECCCCHHHCCCEEEC
SPTSNGIWSKPYNIYGREFVANATTYAQQEIKLLREAQTAKGTYYQFSINNKIIGWIDKR
CCCCCCCCCCCCCCCCHHHHHCHHHHHHHHHHHHHHHHHCCCEEEEEEECCEEEEEECCC
ALTIYPYDSIISSKNVNLAGQITNPTGNGIWSKAYKLEGTTSVAPASKYANQDVNINQQI
EEEEECCHHHHCCCCCEEEEEEECCCCCCCCCEEEEECCCCCCCCCHHHCCCCCCCCCEE
ETQHGSYYNISINGKNIGWLDQKALTLYDVEEYNKAVSFDGTIKNVKSNTIWTKPYRTVG
ECCCCCEEEEEECCCCCCCCCCCCEEEEEHHHHCCEEECCCCCCCCCCCCEEECCCCCCC
TKSVGPAEAYLNKDVQIIREAKTPKGTYYQFKSAGKVIGWLDQKAFEIYDNILYNKVVNM
CCCCCCHHHHHCCCHHHHHHCCCCCCCEEEECCCCCEEEHHHHHHHHHHHHHHHHHHCCH
EAVVENVTGNAVWSAPYKSKGVQGITTANTYKDKTVKLTREAQTSRGTYYEFSYNGKVIG
HHHHHCCCCCEEECCCCCCCCCCCEEECCCCCCCEEEEEEHHCCCCCCEEEEEECCEEEE
WLDKKAFKFYNTLEYDEVYNRDAIITNVTGNTVWTLPYQIYGTKAVNPAATYKNQQARIT
EECHHHHHHHCCCCHHHHCCCCEEEEECCCCEEEEEEEEEEECCCCCHHHHCCCCHHHHH
RKAKTERGIYYQFSINGKNIGWLDEKAFDVYDEIEYNKNIKLTGILSNASGNAIWSEPYR
HHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHHHCCCCCEEEEEEEECCCCCCEECCCEE
VIGTKNVGQATSYANKTVQLVKEAKTTRSTYYQMSINGKVIGWVDKRAFTNVK
EEECCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]