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The map label for this gene is inlA [H]

Identifier: 116872179

GI number: 116872179

Start: 785254

End: 787194

Strand: Direct

Name: inlA [H]

Synonym: lwe0759

Alternate gene names: 116872179

Gene position: 785254-787194 (Clockwise)

Preceding gene: 116872178

Following gene: 116872180

Centisome position: 27.9

GC content: 32.15

Gene sequence:

>1941_bases
ATGAAACAACTAGGTTTTTTAATATTAATGATGACTTTACTATTAAGTGGATTTATTCCAAATGTACATGCAAAGACAGA
GGGACCGCAAGCAGCTAATAATTTACAAGTAGCACCACCAGCTGCAATTAAAGATATTTTTCCAGATCCTGCTATGGCGA
ATGAAGTTTTAAAAGACTTGAATCTTAATAAATTAAATAAACAAAGCACCATCGATACGGTGACTCAAACCGAATTAAAT
AGTATTACTGGATCTTTTCAAGCAATTAATAAAGGAATTAAATCAATAGAGGGTGCGGAATATCTGCAAAATATAACTGA
ACTAGATGTGGAGAAAAACCAAATAACAGATATAACACCAGTTGCAAATCTCAAGAAATTGACCACATTGTTAATTAATA
GTAATCAAATAAAAGATATATCACCAGTGGCTGATTTAGCTAATTTAACTACTTTCTACTGTGGGAATAATCCTATTAGC
GATATTAGTGCAGTTCAAAATCTCACTAAATTATCTATTTTTAATTGTTACACAGCTAACGTAGAAAATATAAGTCCTGT
CAAGAATCTTATTAATCTAAAAACATTAAGTTTAGGAAGTAATAACATACATGATATTAGTGATATAGAAAAATTAACTG
CTCTCGAATATCTTAGTTTTAGTAATAATCCAGTAGAAAATCCAGAAGTTATTGGTAATTTAATAAACTTAAATACATTG
TGGTTATATAATGCGCAGATTAAAAATATTGATTTCACAGCAAGTTTACCTAGTTTAACAAGTGTTTATTTATATAACAA
TCAAATTAGTGACATTAGCGAAGTAAGCAATTGGAGAAATATCGAGTATTTAGAACTAAATGGTAATCAGATATCAGATA
TAACGCCAATAGCCAATCTAACTACTCTTAAAACACTAAAGTTACAGGATCAAAAAATTACCAATCCTGAAATACCTTTC
CAAAAAAATGTTTCCATTGAAAATAAAGTAATAGATAATTTTGGAAATATAGTAGCACCAAATAATATTAGTGATAATGG
GATGTATAATAGCCCTACTTTATCATGGGATTTAAACGAAATAAAAGACAGTCTCTCTTATGACTTTTCAACAAAAATGA
CAATTTTAAAAATAAATGCTACTTTTTCAGGAACAGTGATTCAGCCATTAATAAAAGATAGCACTCGACCTGTCATTACA
GCAGATGAAAAAATTAGTTATCCCGAACGAACAATAAAAACAGCAGCCGAATTTTTAACCGATATTCATGCGACAACAGA
TGACGGCAGTCCAGTCGAGGTGGATTTAAGTGCGGTAGATTTTGATAAGCCAGGAAGTTATACAGTGACTTTAACAGCGG
TAGATTCGGCAGGGAACGTGGCAACTCCAGTAAATGTTATTATTACTATTACAGCGGTAGATATGAGCAAACCTGTCATT
ACAGCAGATGAAAAAATTAGTTATCCCGAACGAACAATAAAAACAGCAGCCGAATTTTTAACCGATATTCATGCGACAAC
AGATGACGGCAGTCCAGTCGAGGTGGATTTAAGTGCGGTAGATTTTGATAAGCCCGGAAGTTATACAGTGACTTTAACAG
CGGTGGATTCGGCGGGAAACGTGGCAACTCCAGTTCAAGTAACAATTATTATTACTAGTTCAGAAAAAATAGATCCGGTT
ATTCCAGTTGTCCCCGAAGAAAGAGATATAAAACCAGAAGAGCCAAAGAAAATAACTATTCTTCCAAAAGATCAGGAAAT
GCTTATAACAATTATTCCAAAAGAAAATATCGAAAAATTAAGTTCAATCAGTGATACCAAAGTAACAGAAAAGAAGGAAG
TAAAGAATAAAACTCTTCCGAAAACTGGTGACCAATTACCTTTTACAGCATTTTGGGGATTGCTTATTATCTCAGCAAGT
ATTTCTTATTTTCGTAAATAA

Upstream 100 bases:

>100_bases
TTGTCATACTTTAGCAGTTGAATTTACTAATTTGGGAAAATAACTTTCGCTTAAATATGTATTATTAGTATAGATGGAAA
AACATGAAGGAGTTAATTGA

Downstream 100 bases:

>100_bases
CCATTTTTGCCTAGGATAAATTCGTATTCTAGGCTTTTTTATGAAAATTGCATTAGAATGTGGTGAAACTTTAGACATAT
AGTTACACTGGCTTCGGTTT

Product: internalin-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 646; Mature: 646

Protein sequence:

>646_residues
MKQLGFLILMMTLLLSGFIPNVHAKTEGPQAANNLQVAPPAAIKDIFPDPAMANEVLKDLNLNKLNKQSTIDTVTQTELN
SITGSFQAINKGIKSIEGAEYLQNITELDVEKNQITDITPVANLKKLTTLLINSNQIKDISPVADLANLTTFYCGNNPIS
DISAVQNLTKLSIFNCYTANVENISPVKNLINLKTLSLGSNNIHDISDIEKLTALEYLSFSNNPVENPEVIGNLINLNTL
WLYNAQIKNIDFTASLPSLTSVYLYNNQISDISEVSNWRNIEYLELNGNQISDITPIANLTTLKTLKLQDQKITNPEIPF
QKNVSIENKVIDNFGNIVAPNNISDNGMYNSPTLSWDLNEIKDSLSYDFSTKMTILKINATFSGTVIQPLIKDSTRPVIT
ADEKISYPERTIKTAAEFLTDIHATTDDGSPVEVDLSAVDFDKPGSYTVTLTAVDSAGNVATPVNVIITITAVDMSKPVI
TADEKISYPERTIKTAAEFLTDIHATTDDGSPVEVDLSAVDFDKPGSYTVTLTAVDSAGNVATPVQVTIIITSSEKIDPV
IPVVPEERDIKPEEPKKITILPKDQEMLITIIPKENIEKLSSISDTKVTEKKEVKNKTLPKTGDQLPFTAFWGLLIISAS
ISYFRK

Sequences:

>Translated_646_residues
MKQLGFLILMMTLLLSGFIPNVHAKTEGPQAANNLQVAPPAAIKDIFPDPAMANEVLKDLNLNKLNKQSTIDTVTQTELN
SITGSFQAINKGIKSIEGAEYLQNITELDVEKNQITDITPVANLKKLTTLLINSNQIKDISPVADLANLTTFYCGNNPIS
DISAVQNLTKLSIFNCYTANVENISPVKNLINLKTLSLGSNNIHDISDIEKLTALEYLSFSNNPVENPEVIGNLINLNTL
WLYNAQIKNIDFTASLPSLTSVYLYNNQISDISEVSNWRNIEYLELNGNQISDITPIANLTTLKTLKLQDQKITNPEIPF
QKNVSIENKVIDNFGNIVAPNNISDNGMYNSPTLSWDLNEIKDSLSYDFSTKMTILKINATFSGTVIQPLIKDSTRPVIT
ADEKISYPERTIKTAAEFLTDIHATTDDGSPVEVDLSAVDFDKPGSYTVTLTAVDSAGNVATPVNVIITITAVDMSKPVI
TADEKISYPERTIKTAAEFLTDIHATTDDGSPVEVDLSAVDFDKPGSYTVTLTAVDSAGNVATPVQVTIIITSSEKIDPV
IPVVPEERDIKPEEPKKITILPKDQEMLITIIPKENIEKLSSISDTKVTEKKEVKNKTLPKTGDQLPFTAFWGLLIISAS
ISYFRK
>Mature_646_residues
MKQLGFLILMMTLLLSGFIPNVHAKTEGPQAANNLQVAPPAAIKDIFPDPAMANEVLKDLNLNKLNKQSTIDTVTQTELN
SITGSFQAINKGIKSIEGAEYLQNITELDVEKNQITDITPVANLKKLTTLLINSNQIKDISPVADLANLTTFYCGNNPIS
DISAVQNLTKLSIFNCYTANVENISPVKNLINLKTLSLGSNNIHDISDIEKLTALEYLSFSNNPVENPEVIGNLINLNTL
WLYNAQIKNIDFTASLPSLTSVYLYNNQISDISEVSNWRNIEYLELNGNQISDITPIANLTTLKTLKLQDQKITNPEIPF
QKNVSIENKVIDNFGNIVAPNNISDNGMYNSPTLSWDLNEIKDSLSYDFSTKMTILKINATFSGTVIQPLIKDSTRPVIT
ADEKISYPERTIKTAAEFLTDIHATTDDGSPVEVDLSAVDFDKPGSYTVTLTAVDSAGNVATPVNVIITITAVDMSKPVI
TADEKISYPERTIKTAAEFLTDIHATTDDGSPVEVDLSAVDFDKPGSYTVTLTAVDSAGNVATPVQVTIIITSSEKIDPV
IPVVPEERDIKPEEPKKITILPKDQEMLITIIPKENIEKLSSISDTKVTEKKEVKNKTLPKTGDQLPFTAFWGLLIISAS
ISYFRK

Specific function: Mediates the entry of Listeria monocytogenes into cells [H]

COG id: COG4886

COG function: function code S; Leucine-rich repeat (LRR) protein

Gene ontology:

Cell location: Secreted, cell wall; Peptidoglycan-anchor [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 14 LRR (leucine-rich) repeats [H]

Homologues:

Organism=Homo sapiens, GI4506013, Length=242, Percent_Identity=30.1652892561983, Blast_Score=93, Evalue=8e-19,
Organism=Homo sapiens, GI55743114, Length=145, Percent_Identity=33.1034482758621, Blast_Score=69, Evalue=2e-11,
Organism=Homo sapiens, GI206725447, Length=208, Percent_Identity=29.3269230769231, Blast_Score=67, Evalue=6e-11,
Organism=Homo sapiens, GI42542396, Length=208, Percent_Identity=29.3269230769231, Blast_Score=67, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17536161, Length=203, Percent_Identity=28.5714285714286, Blast_Score=86, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17554124, Length=248, Percent_Identity=23.7903225806452, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17531555, Length=213, Percent_Identity=29.5774647887324, Blast_Score=70, Evalue=5e-12,
Organism=Drosophila melanogaster, GI21358617, Length=280, Percent_Identity=26.4285714285714, Blast_Score=77, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014755
- InterPro:   IPR019948
- InterPro:   IPR014756
- InterPro:   IPR001611
- InterPro:   IPR013378
- InterPro:   IPR019931
- InterPro:   IPR012569
- InterPro:   IPR001899 [H]

Pfam domain/function: PF09479 Flg_new; PF00746 Gram_pos_anchor; PF00560 LRR_1; PF08191 LRR_adjacent [H]

EC number: NA

Molecular weight: Translated: 70852; Mature: 70852

Theoretical pI: Translated: 4.41; Mature: 4.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQLGFLILMMTLLLSGFIPNVHAKTEGPQAANNLQVAPPAAIKDIFPDPAMANEVLKDL
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEECCCHHHHHCCCCHHHHHHHHHHC
NLNKLNKQSTIDTVTQTELNSITGSFQAINKGIKSIEGAEYLQNITELDVEKNQITDITP
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCC
VANLKKLTTLLINSNQIKDISPVADLANLTTFYCGNNPISDISAVQNLTKLSIFNCYTAN
HHHHHHHHHEEECCCCCCCCCHHHHHHHCEEEEECCCCHHHHHHHHHHHHEEEEEEEECC
VENISPVKNLINLKTLSLGSNNIHDISDIEKLTALEYLSFSNNPVENPEVIGNLINLNTL
CCCCHHHHHHHCEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCEEE
WLYNAQIKNIDFTASLPSLTSVYLYNNQISDISEVSNWRNIEYLELNGNQISDITPIANL
EEEECEEECEEEEECCCCCEEEEEECCCCHHHHHHHCCCCEEEEEECCCCCCCCCCCCCC
TTLKTLKLQDQKITNPEIPFQKNVSIENKVIDNFGNIVAPNNISDNGMYNSPTLSWDLNE
EEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHCCCCEECCCCCCCCCCCCCCCCEEEHHH
IKDSLSYDFSTKMTILKINATFSGTVIQPLIKDSTRPVITADEKISYPERTIKTAAEFLT
HHHHHCCCCCCEEEEEEEECCCCCHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHH
DIHATTDDGSPVEVDLSAVDFDKPGSYTVTLTAVDSAGNVATPVNVIITITAVDMSKPVI
HHHCCCCCCCCEEEEEEEECCCCCCCEEEEEEEECCCCCCCCCEEEEEEEEEEECCCCEE
TADEKISYPERTIKTAAEFLTDIHATTDDGSPVEVDLSAVDFDKPGSYTVTLTAVDSAGN
ECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCEEEEEEEECCCCC
VATPVQVTIIITSSEKIDPVIPVVPEERDIKPEEPKKITILPKDQEMLITIIPKENIEKL
CCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEEECCHHHHHH
SSISDTKVTEKKEVKNKTLPKTGDQLPFTAFWGLLIISASISYFRK
HCCCCCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKQLGFLILMMTLLLSGFIPNVHAKTEGPQAANNLQVAPPAAIKDIFPDPAMANEVLKDL
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEECCCHHHHHCCCCHHHHHHHHHHC
NLNKLNKQSTIDTVTQTELNSITGSFQAINKGIKSIEGAEYLQNITELDVEKNQITDITP
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCC
VANLKKLTTLLINSNQIKDISPVADLANLTTFYCGNNPISDISAVQNLTKLSIFNCYTAN
HHHHHHHHHEEECCCCCCCCCHHHHHHHCEEEEECCCCHHHHHHHHHHHHEEEEEEEECC
VENISPVKNLINLKTLSLGSNNIHDISDIEKLTALEYLSFSNNPVENPEVIGNLINLNTL
CCCCHHHHHHHCEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCEEE
WLYNAQIKNIDFTASLPSLTSVYLYNNQISDISEVSNWRNIEYLELNGNQISDITPIANL
EEEECEEECEEEEECCCCCEEEEEECCCCHHHHHHHCCCCEEEEEECCCCCCCCCCCCCC
TTLKTLKLQDQKITNPEIPFQKNVSIENKVIDNFGNIVAPNNISDNGMYNSPTLSWDLNE
EEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHCCCCEECCCCCCCCCCCCCCCCEEEHHH
IKDSLSYDFSTKMTILKINATFSGTVIQPLIKDSTRPVITADEKISYPERTIKTAAEFLT
HHHHHCCCCCCEEEEEEEECCCCCHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHH
DIHATTDDGSPVEVDLSAVDFDKPGSYTVTLTAVDSAGNVATPVNVIITITAVDMSKPVI
HHHCCCCCCCCEEEEEEEECCCCCCCEEEEEEEECCCCCCCCCEEEEEEEEEEECCCCEE
TADEKISYPERTIKTAAEFLTDIHATTDDGSPVEVDLSAVDFDKPGSYTVTLTAVDSAGN
ECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCEEEEEEEECCCCC
VATPVQVTIIITSSEKIDPVIPVVPEERDIKPEEPKKITILPKDQEMLITIIPKENIEKL
CCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEEECCHHHHHH
SSISDTKVTEKKEVKNKTLPKTGDQLPFTAFWGLLIISASISYFRK
HCCCCCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9541569 [H]