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The map label for this gene is msrR [H]

Identifier: 116871855

GI number: 116871855

Start: 470972

End: 471901

Strand: Direct

Name: msrR [H]

Synonym: lwe0435

Alternate gene names: 116871855

Gene position: 470972-471901 (Clockwise)

Preceding gene: 116871854

Following gene: 116871856

Centisome position: 16.74

GC content: 35.7

Gene sequence:

>930_bases
ATGGCAAGACATTCGCAAAAAAGAAAGGCACGTAAGGGTAGAATCTTTGTTACAATTCTTGTAGCCCTATTAATTTTAGT
TGGTGTAGTTGCAGTTATAGGTTATTTCCAATATCAATCTAGCTTAAAAGAAGCACAAAATGATAGTAAATTAAAAGAGT
ACAAATTTAATGGAGTTAAAGCAGATGGTGACGCGATTAATGTACTGCTTATTGGTAGCGATTCTCGCGGGGCTGATCAA
GGACGTTCAGATAGTTTGATGATTGCCCACTATAATACGAAAACAAATACGCCAAAACTAGTTTCAATCATGCGTGATAC
TTATGTAGATATTCCTGGACATGGTAAAAATAAAATCAATGCAGCATATTCTTACGGAGGACCAGAACTTGTTCGTCAAA
CAATTAAAGAAAACTTTGGTGTCGATGTAGAATATTATGTCGTTGCAAATTTTGAAGGATTCCCTAAAATTGTTGATACT
CTTGCTCCAGAAGGAATCAAAATTAATGCAGAAAAAGATATGTCAAAAAATATTGATGTAAGCATTAAAAAAGGAGAGCA
AGTAATGGATGGTAAAACACTATTACAATATGCTCGCTTCCGTAAAGATGCAGAAGGAGACTTTGGCCGAATTCGTCGTC
AACAACAAGTGTTAGAAGCACTAAAAGAACAAGCATTAGATGTTGGAGATGTTACTAAAATTCCAGATGTTATCGGGAAG
TTACAAGGTTACTCTTCTACAAATATCCCGAATGGCACTCTAATGTCCATTGGCGCAGATTTTCTACTTGGAAAAACAAA
AACAATGGAAAAATTTGCGATTCCAGTTGAAGGAAAATGGCATAACGAACGTATTGAAGGTGCAGGATCCGTCCTTCGTT
TAGATGATATGGCAGACAACGCACAAGCATTACAAGATTTTCTAAAATAA

Upstream 100 bases:

>100_bases
GGGGGTTTCAATCTTTAAAAAATCTTATGGAATTATCACTCTCTTTTTTTGTCATTTTATTGTAATATGTAGGTAAGTTA
CAATAAATGAGGTGTGTAAA

Downstream 100 bases:

>100_bases
AGCAGAACACGGAAATCATTTCTATGGATTTCCGTGTTTTTTTCAGAAAAAAATGCAGCTAGCTTAACTGGAACATGAAA
GTTATGATTAAAAAAATGAT

Product: transcriptional regulator, putative

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MARHSQKRKARKGRIFVTILVALLILVGVVAVIGYFQYQSSLKEAQNDSKLKEYKFNGVKADGDAINVLLIGSDSRGADQ
GRSDSLMIAHYNTKTNTPKLVSIMRDTYVDIPGHGKNKINAAYSYGGPELVRQTIKENFGVDVEYYVVANFEGFPKIVDT
LAPEGIKINAEKDMSKNIDVSIKKGEQVMDGKTLLQYARFRKDAEGDFGRIRRQQQVLEALKEQALDVGDVTKIPDVIGK
LQGYSSTNIPNGTLMSIGADFLLGKTKTMEKFAIPVEGKWHNERIEGAGSVLRLDDMADNAQALQDFLK

Sequences:

>Translated_309_residues
MARHSQKRKARKGRIFVTILVALLILVGVVAVIGYFQYQSSLKEAQNDSKLKEYKFNGVKADGDAINVLLIGSDSRGADQ
GRSDSLMIAHYNTKTNTPKLVSIMRDTYVDIPGHGKNKINAAYSYGGPELVRQTIKENFGVDVEYYVVANFEGFPKIVDT
LAPEGIKINAEKDMSKNIDVSIKKGEQVMDGKTLLQYARFRKDAEGDFGRIRRQQQVLEALKEQALDVGDVTKIPDVIGK
LQGYSSTNIPNGTLMSIGADFLLGKTKTMEKFAIPVEGKWHNERIEGAGSVLRLDDMADNAQALQDFLK
>Mature_308_residues
ARHSQKRKARKGRIFVTILVALLILVGVVAVIGYFQYQSSLKEAQNDSKLKEYKFNGVKADGDAINVLLIGSDSRGADQG
RSDSLMIAHYNTKTNTPKLVSIMRDTYVDIPGHGKNKINAAYSYGGPELVRQTIKENFGVDVEYYVVANFEGFPKIVDTL
APEGIKINAEKDMSKNIDVSIKKGEQVMDGKTLLQYARFRKDAEGDFGRIRRQQQVLEALKEQALDVGDVTKIPDVIGKL
QGYSSTNIPNGTLMSIGADFLLGKTKTMEKFAIPVEGKWHNERIEGAGSVLRLDDMADNAQALQDFLK

Specific function: Involved in sarA attenuation. Affects resistance to oxacillin and teicoplanin, as well as the synthesis of virulence factors [H]

COG id: COG1316

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the LytR/CpsA/Psr regulatory protein family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004474 [H]

Pfam domain/function: PF03816 LytR_cpsA_psr [H]

EC number: NA

Molecular weight: Translated: 34222; Mature: 34090

Theoretical pI: Translated: 9.57; Mature: 9.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARHSQKRKARKGRIFVTILVALLILVGVVAVIGYFQYQSSLKEAQNDSKLKEYKFNGVK
CCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCEE
ADGDAINVLLIGSDSRGADQGRSDSLMIAHYNTKTNTPKLVSIMRDTYVDIPGHGKNKIN
CCCCEEEEEEEECCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHEECCCCCCCCCEE
AAYSYGGPELVRQTIKENFGVDVEYYVVANFEGFPKIVDTLAPEGIKINAEKDMSKNIDV
EEECCCCHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHCCCCEEECCCCCCCCCCCE
SIKKGEQVMDGKTLLQYARFRKDAEGDFGRIRRQQQVLEALKEQALDVGDVTKIPDVIGK
EEECCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
LQGYSSTNIPNGTLMSIGADFLLGKTKTMEKFAIPVEGKWHNERIEGAGSVLRLDDMADN
HCCCCCCCCCCCEEHHHCHHHHHCCCCCHHHHCCCCCCCCCCHHHCCCCCEEEECCCCCC
AQALQDFLK
HHHHHHHHC
>Mature Secondary Structure 
ARHSQKRKARKGRIFVTILVALLILVGVVAVIGYFQYQSSLKEAQNDSKLKEYKFNGVK
CCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCEE
ADGDAINVLLIGSDSRGADQGRSDSLMIAHYNTKTNTPKLVSIMRDTYVDIPGHGKNKIN
CCCCEEEEEEEECCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHEECCCCCCCCCEE
AAYSYGGPELVRQTIKENFGVDVEYYVVANFEGFPKIVDTLAPEGIKINAEKDMSKNIDV
EEECCCCHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHCCCCEEECCCCCCCCCCCE
SIKKGEQVMDGKTLLQYARFRKDAEGDFGRIRRQQQVLEALKEQALDVGDVTKIPDVIGK
EEECCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
LQGYSSTNIPNGTLMSIGADFLLGKTKTMEKFAIPVEGKWHNERIEGAGSVLRLDDMADN
HCCCCCCCCCCCEEHHHCHHHHHCCCCCHHHHCCCCCCCCCCHHHCCCCCEEEECCCCCC
AQALQDFLK
HHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12878519 [H]