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The map label for this gene is atpD [H]

Identifier: 116871845

GI number: 116871845

Start: 447290

End: 448660

Strand: Direct

Name: atpD [H]

Synonym: lwe0425

Alternate gene names: 116871845

Gene position: 447290-448660 (Clockwise)

Preceding gene: 116871844

Following gene: 116871846

Centisome position: 15.89

GC content: 38.07

Gene sequence:

>1371_bases
ATGAAAAAACATACAGGGACCATTATTAGTATTAGTGGTTTTGTTTTAAAAATTGAATTTAACGAGAGTGATTTGCCTGA
AATCAGCCATGCACTTGAATATAAAACGCATCAAGGGACTTATCTAGCTGAGGTTGTTCAGCATACTGGTATTAATACAG
TTTCTGCTATTGCAATTGGAGAAGTTAGTGGTCTAGCCAGAGGAACTGAAGTGGTGAATTTAGGTCACCCAATAGAAGTA
CCTGTTGGAGAATCAGTTCAAGGTAGAATGCTAAATGTATACGGAAAAGCAATTGATGGCAAACCAGAACCAGAAGCTGA
AGTGAAATGGCCGATTTTCCGTGAACAACCATTATTACGTGATTTAGATACTAGTAAAGAAATTTTATACACTGGTATCA
AAGTAATCGACTTAATTTGTCCTATTTTAAAAGGTGGGAAAACTGGTTTATTCGGTGGTGCCGGAGTTGGGAAATCCGTT
TTAATGCAAGAGTTAATTAATAACATTAGTATGATGGGCGGGAACTCCGTATTTACAGGTGTTGGAGAGCGAGTTAGAGA
AGGAATCGGCCTATACAAAGAGTTAGAAGCAAGTGGCGTTTTATCTCAAACTACTGTTGTGCTTGGTCAGATGAATGAAT
CTCCAGGAGTACGGATGCGTGTAGCGCTAACCGGCTTAACTATCGCAGAATATTTACGAGATGAAGAGAAAAAAGACGTT
TTATTATTTATTGATAATGTCTTCCGCTTTATTCAAGCAGGTTCCGAGGTATCTTCTTTACAAGGTAAAATTCCAATTAC
TGGTGGGTATCAATCGACACTCTCTAAAGAAGTTGGAGACTTCCAAGACCGCATCGCGTCTACAAAAGATGGTTCCATTA
CTTCAATTCAATGTGTATTCTTACCAGCGGATGATATTGATGATCCATCAGCGGTTGCTACGTTTAGTCACTTAGACTCA
ACAATTGTATTAGAAAGATCTATTGCTGCACTTGGGATTTTCCCAGCAGTCAACCCGCTTCAATCGTTCTCACGGGCACT
TAATCCAAACTTTGTCGGTGAGCGTCATTATCAATTGGCTGTGCAAGTGAAATATGTTTTACAACGTTATACAGAGTTAC
AGGAAATTATTAATGTATTAGGTATGGCTGAACTAAGTGATGATGATAAAAACCTTGTTCACCGTGCAAGAAAAATTCGT
AATTTCCTTTCACAACCTTTCTACGTTTCAGAGAAATTTACAGGGACAGAAGGAATATTTGTTGAGATGGAAGATTTATT
AGAAAGTATCGAACGTATTTTAGACGGTACTTATGACGACCGTTCTGAACGCGACTTTCTATTTATTGGATCCTACAAGG
ACTTGAAATAG

Upstream 100 bases:

>100_bases
AGCGATATTTGATGCTAGAAAACAAACGTTACAACAAAAAACTAGCGAGTTACTAGATGTCATCAGCGGTGCACAGACGA
TCAGGAAGGAAGAAGAATAA

Downstream 100 bases:

>100_bases
GAGGAGAACAAAATGAAACTTAAAATCGTCTCACCTATGGGCCAGTTTTTTGAAGGTGAAGTAGAAGGATTTGTCATCGA
TACAAAAGACGGTCAACAAA

Product: F0F1 ATP synthase subunit beta

Products: NA

Alternate protein names: ATP synthase F1 sector subunit beta 1; F-ATPase subunit beta 1 [H]

Number of amino acids: Translated: 456; Mature: 456

Protein sequence:

>456_residues
MKKHTGTIISISGFVLKIEFNESDLPEISHALEYKTHQGTYLAEVVQHTGINTVSAIAIGEVSGLARGTEVVNLGHPIEV
PVGESVQGRMLNVYGKAIDGKPEPEAEVKWPIFREQPLLRDLDTSKEILYTGIKVIDLICPILKGGKTGLFGGAGVGKSV
LMQELINNISMMGGNSVFTGVGERVREGIGLYKELEASGVLSQTTVVLGQMNESPGVRMRVALTGLTIAEYLRDEEKKDV
LLFIDNVFRFIQAGSEVSSLQGKIPITGGYQSTLSKEVGDFQDRIASTKDGSITSIQCVFLPADDIDDPSAVATFSHLDS
TIVLERSIAALGIFPAVNPLQSFSRALNPNFVGERHYQLAVQVKYVLQRYTELQEIINVLGMAELSDDDKNLVHRARKIR
NFLSQPFYVSEKFTGTEGIFVEMEDLLESIERILDGTYDDRSERDFLFIGSYKDLK

Sequences:

>Translated_456_residues
MKKHTGTIISISGFVLKIEFNESDLPEISHALEYKTHQGTYLAEVVQHTGINTVSAIAIGEVSGLARGTEVVNLGHPIEV
PVGESVQGRMLNVYGKAIDGKPEPEAEVKWPIFREQPLLRDLDTSKEILYTGIKVIDLICPILKGGKTGLFGGAGVGKSV
LMQELINNISMMGGNSVFTGVGERVREGIGLYKELEASGVLSQTTVVLGQMNESPGVRMRVALTGLTIAEYLRDEEKKDV
LLFIDNVFRFIQAGSEVSSLQGKIPITGGYQSTLSKEVGDFQDRIASTKDGSITSIQCVFLPADDIDDPSAVATFSHLDS
TIVLERSIAALGIFPAVNPLQSFSRALNPNFVGERHYQLAVQVKYVLQRYTELQEIINVLGMAELSDDDKNLVHRARKIR
NFLSQPFYVSEKFTGTEGIFVEMEDLLESIERILDGTYDDRSERDFLFIGSYKDLK
>Mature_456_residues
MKKHTGTIISISGFVLKIEFNESDLPEISHALEYKTHQGTYLAEVVQHTGINTVSAIAIGEVSGLARGTEVVNLGHPIEV
PVGESVQGRMLNVYGKAIDGKPEPEAEVKWPIFREQPLLRDLDTSKEILYTGIKVIDLICPILKGGKTGLFGGAGVGKSV
LMQELINNISMMGGNSVFTGVGERVREGIGLYKELEASGVLSQTTVVLGQMNESPGVRMRVALTGLTIAEYLRDEEKKDV
LLFIDNVFRFIQAGSEVSSLQGKIPITGGYQSTLSKEVGDFQDRIASTKDGSITSIQCVFLPADDIDDPSAVATFSHLDS
TIVLERSIAALGIFPAVNPLQSFSRALNPNFVGERHYQLAVQVKYVLQRYTELQEIINVLGMAELSDDDKNLVHRARKIR
NFLSQPFYVSEKFTGTEGIFVEMEDLLESIERILDGTYDDRSERDFLFIGSYKDLK

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits [H]

COG id: COG0055

COG function: function code C; F0F1-type ATP synthase, beta subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI32189394, Length=457, Percent_Identity=51.6411378555799, Blast_Score=461, Evalue=1e-130,
Organism=Homo sapiens, GI19913424, Length=358, Percent_Identity=27.3743016759777, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI19913428, Length=424, Percent_Identity=23.8207547169811, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI19913426, Length=425, Percent_Identity=23.0588235294118, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI50345984, Length=393, Percent_Identity=23.1552162849873, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI4757810, Length=393, Percent_Identity=23.1552162849873, Blast_Score=84, Evalue=3e-16,
Organism=Escherichia coli, GI1790170, Length=451, Percent_Identity=52.3281596452328, Blast_Score=467, Evalue=1e-133,
Organism=Escherichia coli, GI1788251, Length=367, Percent_Identity=28.6103542234332, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1790172, Length=396, Percent_Identity=24.2424242424242, Blast_Score=100, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI25144756, Length=458, Percent_Identity=50.6550218340611, Blast_Score=445, Evalue=1e-125,
Organism=Caenorhabditis elegans, GI17565854, Length=326, Percent_Identity=29.4478527607362, Blast_Score=121, Evalue=6e-28,
Organism=Caenorhabditis elegans, GI17570191, Length=409, Percent_Identity=24.2053789731051, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17510931, Length=387, Percent_Identity=23.5142118863049, Blast_Score=89, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI71988080, Length=371, Percent_Identity=22.1024258760108, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71988063, Length=371, Percent_Identity=22.3719676549865, Blast_Score=76, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6322581, Length=457, Percent_Identity=53.1728665207877, Blast_Score=480, Evalue=1e-136,
Organism=Saccharomyces cerevisiae, GI6319603, Length=365, Percent_Identity=24.3835616438356, Blast_Score=92, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6320016, Length=233, Percent_Identity=27.0386266094421, Blast_Score=83, Evalue=8e-17,
Organism=Saccharomyces cerevisiae, GI6319370, Length=353, Percent_Identity=23.2294617563739, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24638766, Length=457, Percent_Identity=50.9846827133479, Blast_Score=455, Evalue=1e-128,
Organism=Drosophila melanogaster, GI28574560, Length=462, Percent_Identity=52.3809523809524, Blast_Score=451, Evalue=1e-127,
Organism=Drosophila melanogaster, GI20129479, Length=328, Percent_Identity=28.3536585365854, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24583992, Length=328, Percent_Identity=28.3536585365854, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24583988, Length=330, Percent_Identity=29.3939393939394, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24583986, Length=330, Percent_Identity=29.3939393939394, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24583984, Length=330, Percent_Identity=29.3939393939394, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI281361666, Length=411, Percent_Identity=24.330900243309, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24646341, Length=411, Percent_Identity=24.330900243309, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI17136796, Length=411, Percent_Identity=24.330900243309, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24658560, Length=370, Percent_Identity=22.7027027027027, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24638768, Length=92, Percent_Identity=41.304347826087, Blast_Score=75, Evalue=8e-14,

Paralogues:

None

Copy number: 10836 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR005722
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 50171; Mature: 50171

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKHTGTIISISGFVLKIEFNESDLPEISHALEYKTHQGTYLAEVVQHTGINTVSAIAIG
CCCCCCCEEEECCEEEEEEECCCCCHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHEEHH
EVSGLARGTEVVNLGHPIEVPVGESVQGRMLNVYGKAIDGKPEPEAEVKWPIFREQPLLR
HHHHHCCCCEEEECCCCEECCCCCCCCCCEEEEECCCCCCCCCCCCCEECCCCCCCCHHH
DLDTSKEILYTGIKVIDLICPILKGGKTGLFGGAGVGKSVLMQELINNISMMGGNSVFTG
HCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHH
VGERVREGIGLYKELEASGVLSQTTVVLGQMNESPGVRMRVALTGLTIAEYLRDEEKKDV
HHHHHHHHHCHHHHHHHCCCHHHHEEEEEECCCCCCCEEEEEEHHHHHHHHHCCCCCCCE
LLFIDNVFRFIQAGSEVSSLQGKIPITGGYQSTLSKEVGDFQDRIASTKDGSITSIQCVF
EEEHHHHHHHHHCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEE
LPADDIDDPSAVATFSHLDSTIVLERSIAALGIFPAVNPLQSFSRALNPNFVGERHYQLA
ECCCCCCCCHHHHHHHHCCCEEEEHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCHHHHH
VQVKYVLQRYTELQEIINVLGMAELSDDDKNLVHRARKIRNFLSQPFYVSEKFTGTEGIF
HHHHHHHHHHHHHHHHHHHHCCHHCCCCHHHHHHHHHHHHHHHCCCEEEECCCCCCCCEE
VEMEDLLESIERILDGTYDDRSERDFLFIGSYKDLK
EEHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCC
>Mature Secondary Structure
MKKHTGTIISISGFVLKIEFNESDLPEISHALEYKTHQGTYLAEVVQHTGINTVSAIAIG
CCCCCCCEEEECCEEEEEEECCCCCHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHEEHH
EVSGLARGTEVVNLGHPIEVPVGESVQGRMLNVYGKAIDGKPEPEAEVKWPIFREQPLLR
HHHHHCCCCEEEECCCCEECCCCCCCCCCEEEEECCCCCCCCCCCCCEECCCCCCCCHHH
DLDTSKEILYTGIKVIDLICPILKGGKTGLFGGAGVGKSVLMQELINNISMMGGNSVFTG
HCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHH
VGERVREGIGLYKELEASGVLSQTTVVLGQMNESPGVRMRVALTGLTIAEYLRDEEKKDV
HHHHHHHHHCHHHHHHHCCCHHHHEEEEEECCCCCCCEEEEEEHHHHHHHHHCCCCCCCE
LLFIDNVFRFIQAGSEVSSLQGKIPITGGYQSTLSKEVGDFQDRIASTKDGSITSIQCVF
EEEHHHHHHHHHCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEE
LPADDIDDPSAVATFSHLDSTIVLERSIAALGIFPAVNPLQSFSRALNPNFVGERHYQLA
ECCCCCCCCHHHHHHHHCCCEEEEHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCHHHHH
VQVKYVLQRYTELQEIINVLGMAELSDDDKNLVHRARKIRNFLSQPFYVSEKFTGTEGIF
HHHHHHHHHHHHHHHHHHHHCCHHCCCCHHHHHHHHHHHHHHHCCCEEEECCCCCCCCEE
VEMEDLLESIERILDGTYDDRSERDFLFIGSYKDLK
EEHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]