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The map label for this gene is gufA [H]

Identifier: 116871797

GI number: 116871797

Start: 390256

End: 391065

Strand: Direct

Name: gufA [H]

Synonym: lwe0377

Alternate gene names: 116871797

Gene position: 390256-391065 (Clockwise)

Preceding gene: 116871796

Following gene: 116871798

Centisome position: 13.87

GC content: 39.51

Gene sequence:

>810_bases
TTGTTAAACTACTTATCTTCACTAAACCCGGTATTACTAGCGCTTCTTGCCGGGATTTTCACATGGGCTTGTACAGCAGC
CGGCGCATCACTTGTATTTTTCTTTAAAAATTTAAATAAAAAATGGGGCAATATCATGCTTGGTTTCGCTGCTGGTGTTA
TGTTAGCTGCGAGTTTTTGGTCCCTTCTTGCACCTGCGATAGAAATGAGTAAGGATTTAGGGAAATTTTCTTTTGTTCCT
GCTTTAGTTGGTTTTTTACTAGGGGGAATATTTTTACGGGTGATTGACCGAATTATTCCCCATTTACATTTTGGATTTCC
TGAGCAAGCAAAAGAAGGGCCGAAAACTTCCCTTCGAAAAAGTATTTTATTAGTTTTATCTATTACTATTCATAACATTC
CAGAAGGAGCAGCTGTTGGGGTTGCATTTGGAGCAGTAATAACGGGAGACACAGAAACACTTATAACTGCTATTGTGCTG
GCTTTAGGTATTGGTATTCAAAATTTTCCAGAAGGAGCAGCTGTTTCCATTCCCTTGCGCGGAGAAGGACTTTCTAGACG
GAAAAGTTTTTGGTACGGTCAATTATCTGCGGTTGTAGAACCTGTTTTTGCAGTTATTGGAGCAGTATTAGTCGTTTTTG
TCACGCCAATATTGCCTTTTGCATTAGCTTTTGCTGCAGGAGCGATGATTTTTGTAATAGTGGAAGAATTAATTCCAGAA
TCACAAGTGGAAGGATCAACAGATTTAGCAACTGCGGCAACTATGGCTGGTTTTGCAGTGATGATGGTTTTAGACGTAGC
ATTAGGATAA

Upstream 100 bases:

>100_bases
GGGCTGTAAAAATGAGTATAAATAAATCACGGTCTTTTATTGAAGGCTTCAAACAAGGTTGGTCAAGTAAATAAAGGTAT
AAGAAAAGGGAGAAACTCTA

Downstream 100 bases:

>100_bases
AAACATGTTAAAAAACGTTCTCTAATATTTGCGGATTGCGTTTTTTTGCGGTAAAATTAATAGTGAAACATTTCACAATA
TGCTAGTTTTCAGGGGTAAT

Product: ZIP zinc transporter family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 269; Mature: 269

Protein sequence:

>269_residues
MLNYLSSLNPVLLALLAGIFTWACTAAGASLVFFFKNLNKKWGNIMLGFAAGVMLAASFWSLLAPAIEMSKDLGKFSFVP
ALVGFLLGGIFLRVIDRIIPHLHFGFPEQAKEGPKTSLRKSILLVLSITIHNIPEGAAVGVAFGAVITGDTETLITAIVL
ALGIGIQNFPEGAAVSIPLRGEGLSRRKSFWYGQLSAVVEPVFAVIGAVLVVFVTPILPFALAFAAGAMIFVIVEELIPE
SQVEGSTDLATAATMAGFAVMMVLDVALG

Sequences:

>Translated_269_residues
MLNYLSSLNPVLLALLAGIFTWACTAAGASLVFFFKNLNKKWGNIMLGFAAGVMLAASFWSLLAPAIEMSKDLGKFSFVP
ALVGFLLGGIFLRVIDRIIPHLHFGFPEQAKEGPKTSLRKSILLVLSITIHNIPEGAAVGVAFGAVITGDTETLITAIVL
ALGIGIQNFPEGAAVSIPLRGEGLSRRKSFWYGQLSAVVEPVFAVIGAVLVVFVTPILPFALAFAAGAMIFVIVEELIPE
SQVEGSTDLATAATMAGFAVMMVLDVALG
>Mature_269_residues
MLNYLSSLNPVLLALLAGIFTWACTAAGASLVFFFKNLNKKWGNIMLGFAAGVMLAASFWSLLAPAIEMSKDLGKFSFVP
ALVGFLLGGIFLRVIDRIIPHLHFGFPEQAKEGPKTSLRKSILLVLSITIHNIPEGAAVGVAFGAVITGDTETLITAIVL
ALGIGIQNFPEGAAVSIPLRGEGLSRRKSFWYGQLSAVVEPVFAVIGAVLVVFVTPILPFALAFAAGAMIFVIVEELIPE
SQVEGSTDLATAATMAGFAVMMVLDVALG

Specific function: Mediates Zinc Uptake. May Also Transport Other Divalent Cations Such As Copper And Cadmium Ions. [C]

COG id: COG0428

COG function: function code P; Predicted divalent heavy-metal cations transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI229577418, Length=334, Percent_Identity=45.8083832335329, Blast_Score=246, Evalue=1e-65,
Organism=Homo sapiens, GI229577422, Length=341, Percent_Identity=44.8680351906158, Blast_Score=244, Evalue=7e-65,
Organism=Escherichia coli, GI1789419, Length=266, Percent_Identity=29.6992481203008, Blast_Score=77, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17507805, Length=322, Percent_Identity=39.1304347826087, Blast_Score=190, Evalue=7e-49,
Organism=Drosophila melanogaster, GI24652846, Length=161, Percent_Identity=51.5527950310559, Blast_Score=175, Evalue=3e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003689 [H]

Pfam domain/function: PF02535 Zip [H]

EC number: NA

Molecular weight: Translated: 28323; Mature: 28323

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNYLSSLNPVLLALLAGIFTWACTAAGASLVFFFKNLNKKWGNIMLGFAAGVMLAASFW
CCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLLAPAIEMSKDLGKFSFVPALVGFLLGGIFLRVIDRIIPHLHFGFPEQAKEGPKTSLRK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHH
SILLVLSITIHNIPEGAAVGVAFGAVITGDTETLITAIVLALGIGIQNFPEGAAVSIPLR
HHHHHHHHHHHCCCCCHHHHHHHHHHEECCHHHHHHHHHHHHHCCCCCCCCCCEEEEEEC
GEGLSRRKSFWYGQLSAVVEPVFAVIGAVLVVFVTPILPFALAFAAGAMIFVIVEELIPE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
SQVEGSTDLATAATMAGFAVMMVLDVALG
HHCCCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLNYLSSLNPVLLALLAGIFTWACTAAGASLVFFFKNLNKKWGNIMLGFAAGVMLAASFW
CCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLLAPAIEMSKDLGKFSFVPALVGFLLGGIFLRVIDRIIPHLHFGFPEQAKEGPKTSLRK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHH
SILLVLSITIHNIPEGAAVGVAFGAVITGDTETLITAIVLALGIGIQNFPEGAAVSIPLR
HHHHHHHHHHHCCCCCHHHHHHHHHHEECCHHHHHHHHHHHHHCCCCCCCCCCEEEEEEC
GEGLSRRKSFWYGQLSAVVEPVFAVIGAVLVVFVTPILPFALAFAAGAMIFVIVEELIPE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
SQVEGSTDLATAATMAGFAVMMVLDVALG
HHCCCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7934835 [H]