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The map label for this gene is iap [H]

Identifier: 116871762

GI number: 116871762

Start: 363057

End: 363740

Strand: Direct

Name: iap [H]

Synonym: lwe0342

Alternate gene names: 116871762

Gene position: 363057-363740 (Clockwise)

Preceding gene: 116871761

Following gene: 116871763

Centisome position: 12.9

GC content: 33.63

Gene sequence:

>684_bases
TTGAAAATAATAGCAACGAGAAGAAAGAGTTTTTTTGCGTTAATAGCTTTAATGATTTCTTTTTCAGTACTATTTTTACC
AACAAATAATGCGTTAGCGGCTACAACATACAAAATGACCACAACAGCAGATGCAAATATTCGCACATCGGATTCGACAA
AAGGGAAAATCATCGGTCTTTACAAAAAGGGAACAACCATTACTTATACAGCAAAAACCAAAAATAATTGGTATAAAACA
ACTTATAAAGGTAAAACAGGTTATGTTTCAGGCAAATGTCTTACTACATACAAGGCACCTGTTGCTACAACTCAAAGCTT
TACCTCTTTAAATAATGAAGCAAAGAAACACATTGGTAAACGTTATAAAATCGGTGCAACTGGCCCGAGCTGTTTTGACT
GTTCAGGTTATACTCAGTATGTATTTTCAAAAGGAATTAAAAAATCTATTCCACGTACAGCAAAACAACAATATGCTTCC
GCTAAGAAGATTAAAGCTAGCGAATTAAAAAACGGCGACTTAATTTTCTTTAATTATGGCAGAGGTATTGCCCATGTTGG
GATTTATGTGGGAAATGGCAAAATGCTTAATGCGCAAAATAATGGTGTTAAATACGACACAATCAAATCTGGCTATTGGA
AAAAATATATTGCTGGATACGGTCGTGTAACAAACTTAAAATAA

Upstream 100 bases:

>100_bases
TCATAACTGTTACACAATAACGTCAAGTTTTAAAATACCTGTATTACAACTGTAACATTAACTTGGTATGCTATCTGTAT
ATAAAAAAGGGGTGCGTGGA

Downstream 100 bases:

>100_bases
TCTAAAAAAGCGTCACTTCATTGTGATGCTTTTTTTATTTGAATAATAAGGAGGAATTGTTAAATGGAATACAGAATAAA
AGAAATGCCACTAGAAGAAC

Product: NLP/P60 family wall-associated hydrolase

Products: NA

Alternate protein names: Invasion-associated protein [H]

Number of amino acids: Translated: 227; Mature: 227

Protein sequence:

>227_residues
MKIIATRRKSFFALIALMISFSVLFLPTNNALAATTYKMTTTADANIRTSDSTKGKIIGLYKKGTTITYTAKTKNNWYKT
TYKGKTGYVSGKCLTTYKAPVATTQSFTSLNNEAKKHIGKRYKIGATGPSCFDCSGYTQYVFSKGIKKSIPRTAKQQYAS
AKKIKASELKNGDLIFFNYGRGIAHVGIYVGNGKMLNAQNNGVKYDTIKSGYWKKYIAGYGRVTNLK

Sequences:

>Translated_227_residues
MKIIATRRKSFFALIALMISFSVLFLPTNNALAATTYKMTTTADANIRTSDSTKGKIIGLYKKGTTITYTAKTKNNWYKT
TYKGKTGYVSGKCLTTYKAPVATTQSFTSLNNEAKKHIGKRYKIGATGPSCFDCSGYTQYVFSKGIKKSIPRTAKQQYAS
AKKIKASELKNGDLIFFNYGRGIAHVGIYVGNGKMLNAQNNGVKYDTIKSGYWKKYIAGYGRVTNLK
>Mature_227_residues
MKIIATRRKSFFALIALMISFSVLFLPTNNALAATTYKMTTTADANIRTSDSTKGKIIGLYKKGTTITYTAKTKNNWYKT
TYKGKTGYVSGKCLTTYKAPVATTQSFTSLNNEAKKHIGKRYKIGATGPSCFDCSGYTQYVFSKGIKKSIPRTAKQQYAS
AKKIKASELKNGDLIFFNYGRGIAHVGIYVGNGKMLNAQNNGVKYDTIKSGYWKKYIAGYGRVTNLK

Specific function: This major extracellular protein may be involved in the invasion of non-professional phagocytic cells by Listeria [H]

COG id: COG0791

COG function: function code M; Cell wall-associated hydrolases (invasion-associated proteins)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 LysM repeats [H]

Homologues:

Organism=Escherichia coli, GI1787944, Length=123, Percent_Identity=42.2764227642276, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1788501, Length=98, Percent_Identity=35.7142857142857, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1786421, Length=116, Percent_Identity=31.8965517241379, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788001, Length=109, Percent_Identity=33.0275229357798, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000064
- InterPro:   IPR018392
- InterPro:   IPR002482
- InterPro:   IPR003646
- InterPro:   IPR013247 [H]

Pfam domain/function: PF01476 LysM; PF00877 NLPC_P60; PF08239 SH3_3 [H]

EC number: NA

Molecular weight: Translated: 25096; Mature: 25096

Theoretical pI: Translated: 10.71; Mature: 10.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIIATRRKSFFALIALMISFSVLFLPTNNALAATTYKMTTTADANIRTSDSTKGKIIGL
CCEEEHHHHHHHHHHHHHHHCEEEEEECCCCEEEEEEEEEEECCCEEEECCCCCCEEEEE
YKKGTTITYTAKTKNNWYKTTYKGKTGYVSGKCLTTYKAPVATTQSFTSLNNEAKKHIGK
EECCCEEEEEEECCCCEEEEEECCCCCEECCEEEEEECCCCCCCHHHHHHHHHHHHHCCC
RYKIGATGPSCFDCSGYTQYVFSKGIKKSIPRTAKQQYASAKKIKASELKNGDLIFFNYG
EEEECCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCEEEEECC
RGIAHVGIYVGNGKMLNAQNNGVKYDTIKSGYWKKYIAGYGRVTNLK
CCEEEEEEEECCCEEEECCCCCEEEEEECCCHHHHHHHCCCEEECCC
>Mature Secondary Structure
MKIIATRRKSFFALIALMISFSVLFLPTNNALAATTYKMTTTADANIRTSDSTKGKIIGL
CCEEEHHHHHHHHHHHHHHHCEEEEEECCCCEEEEEEEEEEECCCEEEECCCCCCEEEEE
YKKGTTITYTAKTKNNWYKTTYKGKTGYVSGKCLTTYKAPVATTQSFTSLNNEAKKHIGK
EECCCEEEEEEECCCCEEEEEECCCCCEECCEEEEEECCCCCCCHHHHHHHHHHHHHCCC
RYKIGATGPSCFDCSGYTQYVFSKGIKKSIPRTAKQQYASAKKIKASELKNGDLIFFNYG
EEEECCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCEEEEECC
RGIAHVGIYVGNGKMLNAQNNGVKYDTIKSGYWKKYIAGYGRVTNLK
CCEEEEEEEECCCEEEECCCCCEEEEEECCCHHHHHHHCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2111287; 1459966; 11679669 [H]