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The map label for this gene is bglC [H]

Identifier: 116871687

GI number: 116871687

Start: 290647

End: 292065

Strand: Direct

Name: bglC [H]

Synonym: lwe0267

Alternate gene names: 116871687

Gene position: 290647-292065 (Clockwise)

Preceding gene: 116871686

Following gene: 116871688

Centisome position: 10.33

GC content: 37.07

Gene sequence:

>1419_bases
ATGGAATTTAGAAAAAACAAGGCTTTTCCTACAGATTTTTTATGGGGAGCATCAACGTCTTCTTTTCAAGTGGAAGGTGC
TTGGCAGGAAGATGGAAAAGGATTATCAGTTATTGATGTTATGAAAAAGAATCCAAAAATAACGGATTTTACAGTTGCGG
TAGATCATTATCATCGAATGAAGGAAGACGTAGCATTAATGGCCGAATTAGGTCTTAAAGTGTATCGATTTTCTATTGCA
TGGACACGAATTTTCCCTAGTGGGCGTGGCGATATCAACCAAAAGGGCGTTGATTTTTACAATGATTTAATTGATGAACT
TTGTAAATATGGAATTGAACCTCTTGTTACTATTTATCACTTTGATTATCCACAAAGTTTAGTGGAAGAATACGGTGGCT
GGATGTCGCGCAAAAGTGTGGAAGATTACCGTGCATATGCAGAATTTTTATTCCAAACATATGGTGATCGTGTTAAATAT
TGGTTGACGATTAACGAACAAGATCATGTCGTGCGCATTCCAAGTCGTCTAGGTCTTACTGGAGAAAATAAGTATGAGCA
GTTAAAACTTGGATATCAAGCGAACCACCATATGTGTGTAGCAACTGCAGAAACAATTAAAACATTCCATAAGCTTGGAC
TAAAAGGCAAAATTGGGCCAGCAGTTTCCTTCTCAATGATTCATCCAGCTAGTTCTAATCCGGATGATGTATTAGCAAGT
CAAGATGCGATGTTAGTGAAGCATAATTATTTACTTGATTTACATTGTAATGGGGAGTACCGCGCTCCTTTGTGGCAATA
TTTGCTTGACCGAGACTTTGCTCCAAAAATAGAAGACGGGGATATGCAGTTGATGAAAGAAAACCCACCTACAATGATTG
GTGTGAACTATTATTTTTCAGAAACAGTTAAAGCATTTCCGGTATCAGAAGAATTTCCACTTGGTTATCAAAAAGAATCA
CTACTCCCAGAAGCTGAGGCAGGCGTTTTCCAAGTAATAAAAAATAACGAACTTACTGCTACGGATTGGGGCTGGGAAAT
CGACCCACTGGGCTTACGTTTAACATTAAGGGAATTGCATGAACGTTACCATTTACCATTAATAATTACGGAAAATGGAA
TGGGCGCATATGATAAACTAGAGGCGGGAGATGTTGTAAATGATGATTACCGAATTTCGTATTTAAGAGAACATATAAAA
CAAACGAAACTCGCAATTAATGATGGTGTCACTGTACTTGGTTACTGTTCATGGAGCTTTATGGATATAGTTAGTGGTCG
AAACGGCATCGATAAACGATATGGATTTGTATATATAAACCGGGAAAACTTTGATTTAAAAGATATGCGAAGAATTAAAA
AGAAAAGTTTTTACTGGTATCAAAAAGTCATCACTTCAAATGGAGAAACCCTGTCATAA

Upstream 100 bases:

>100_bases
GACCCGGAATAAGATAGAAACTTATCGAAAGAAATTTCGTGAGCTTTTGTCTAATTTCGGGTCATTTTTTGTGTAAAAAG
ATACTAGGAGGCAGTTACAT

Downstream 100 bases:

>100_bases
CTTAACTTTCCTAGATATAAACTAAACTATTGAAGAGGAATAAAAGATGATAATAAAAAAAGTTTTTAATAATAATGTTG
TTTTAGTCATTGAAAATCCT

Product: glycoside hydrolase family protein

Products: NA

Alternate protein names: 6-phospho-beta-glucosidase [H]

Number of amino acids: Translated: 472; Mature: 472

Protein sequence:

>472_residues
MEFRKNKAFPTDFLWGASTSSFQVEGAWQEDGKGLSVIDVMKKNPKITDFTVAVDHYHRMKEDVALMAELGLKVYRFSIA
WTRIFPSGRGDINQKGVDFYNDLIDELCKYGIEPLVTIYHFDYPQSLVEEYGGWMSRKSVEDYRAYAEFLFQTYGDRVKY
WLTINEQDHVVRIPSRLGLTGENKYEQLKLGYQANHHMCVATAETIKTFHKLGLKGKIGPAVSFSMIHPASSNPDDVLAS
QDAMLVKHNYLLDLHCNGEYRAPLWQYLLDRDFAPKIEDGDMQLMKENPPTMIGVNYYFSETVKAFPVSEEFPLGYQKES
LLPEAEAGVFQVIKNNELTATDWGWEIDPLGLRLTLRELHERYHLPLIITENGMGAYDKLEAGDVVNDDYRISYLREHIK
QTKLAINDGVTVLGYCSWSFMDIVSGRNGIDKRYGFVYINRENFDLKDMRRIKKKSFYWYQKVITSNGETLS

Sequences:

>Translated_472_residues
MEFRKNKAFPTDFLWGASTSSFQVEGAWQEDGKGLSVIDVMKKNPKITDFTVAVDHYHRMKEDVALMAELGLKVYRFSIA
WTRIFPSGRGDINQKGVDFYNDLIDELCKYGIEPLVTIYHFDYPQSLVEEYGGWMSRKSVEDYRAYAEFLFQTYGDRVKY
WLTINEQDHVVRIPSRLGLTGENKYEQLKLGYQANHHMCVATAETIKTFHKLGLKGKIGPAVSFSMIHPASSNPDDVLAS
QDAMLVKHNYLLDLHCNGEYRAPLWQYLLDRDFAPKIEDGDMQLMKENPPTMIGVNYYFSETVKAFPVSEEFPLGYQKES
LLPEAEAGVFQVIKNNELTATDWGWEIDPLGLRLTLRELHERYHLPLIITENGMGAYDKLEAGDVVNDDYRISYLREHIK
QTKLAINDGVTVLGYCSWSFMDIVSGRNGIDKRYGFVYINRENFDLKDMRRIKKKSFYWYQKVITSNGETLS
>Mature_472_residues
MEFRKNKAFPTDFLWGASTSSFQVEGAWQEDGKGLSVIDVMKKNPKITDFTVAVDHYHRMKEDVALMAELGLKVYRFSIA
WTRIFPSGRGDINQKGVDFYNDLIDELCKYGIEPLVTIYHFDYPQSLVEEYGGWMSRKSVEDYRAYAEFLFQTYGDRVKY
WLTINEQDHVVRIPSRLGLTGENKYEQLKLGYQANHHMCVATAETIKTFHKLGLKGKIGPAVSFSMIHPASSNPDDVLAS
QDAMLVKHNYLLDLHCNGEYRAPLWQYLLDRDFAPKIEDGDMQLMKENPPTMIGVNYYFSETVKAFPVSEEFPLGYQKES
LLPEAEAGVFQVIKNNELTATDWGWEIDPLGLRLTLRELHERYHLPLIITENGMGAYDKLEAGDVVNDDYRISYLREHIK
QTKLAINDGVTVLGYCSWSFMDIVSGRNGIDKRYGFVYINRENFDLKDMRRIKKKSFYWYQKVITSNGETLS

Specific function: Is able to catalyze the hydrolysis of aryl-phospho-beta- D-glucosides such as 4-methylumbelliferyl-phospho-beta-D- glucopyranoside (MUG-P), phosphoarbutin and phosphosalicin. Is not essential for growth on arbutin and salicin as the sole carbon source [H]

COG id: COG2723

COG function: function code G; Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 1 family [H]

Homologues:

Organism=Homo sapiens, GI32481206, Length=474, Percent_Identity=31.2236286919831, Blast_Score=214, Evalue=2e-55,
Organism=Homo sapiens, GI13273313, Length=485, Percent_Identity=31.9587628865979, Blast_Score=210, Evalue=2e-54,
Organism=Homo sapiens, GI110681710, Length=485, Percent_Identity=30.7216494845361, Blast_Score=206, Evalue=3e-53,
Organism=Homo sapiens, GI28376633, Length=473, Percent_Identity=26.215644820296, Blast_Score=167, Evalue=1e-41,
Organism=Homo sapiens, GI24497614, Length=490, Percent_Identity=27.5510204081633, Blast_Score=162, Evalue=7e-40,
Organism=Homo sapiens, GI190360571, Length=131, Percent_Identity=33.587786259542, Blast_Score=77, Evalue=4e-14,
Organism=Escherichia coli, GI2367174, Length=493, Percent_Identity=40.3651115618661, Blast_Score=354, Evalue=9e-99,
Organism=Escherichia coli, GI1789070, Length=484, Percent_Identity=39.2561983471074, Blast_Score=344, Evalue=6e-96,
Organism=Escherichia coli, GI2367270, Length=478, Percent_Identity=38.0753138075314, Blast_Score=338, Evalue=3e-94,
Organism=Caenorhabditis elegans, GI17552856, Length=474, Percent_Identity=30.379746835443, Blast_Score=204, Evalue=6e-53,
Organism=Caenorhabditis elegans, GI17539390, Length=480, Percent_Identity=30.625, Blast_Score=202, Evalue=2e-52,
Organism=Drosophila melanogaster, GI21356577, Length=489, Percent_Identity=28.4253578732106, Blast_Score=186, Evalue=3e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001360
- InterPro:   IPR018120
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00232 Glyco_hydro_1 [H]

EC number: =3.2.1.86 [H]

Molecular weight: Translated: 54524; Mature: 54524

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: PS00572 GLYCOSYL_HYDROL_F1_1 ; PS00653 GLYCOSYL_HYDROL_F1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFRKNKAFPTDFLWGASTSSFQVEGAWQEDGKGLSVIDVMKKNPKITDFTVAVDHYHRM
CCCCCCCCCCCCEEECCCCCCEEEEECHHCCCCCCEEEEHHHCCCCEEEEEEEHHHHHHH
KEDVALMAELGLKVYRFSIAWTRIFPSGRGDINQKGVDFYNDLIDELCKYGIEPLVTIYH
HHHHHHHHHHCCEEEEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEE
FDYPQSLVEEYGGWMSRKSVEDYRAYAEFLFQTYGDRVKYWLTINEQDHVVRIPSRLGLT
CCCHHHHHHHHCCHHCCCCHHHHHHHHHHHHHHCCCEEEEEEEECCCCCEEECHHHCCCC
GENKYEQLKLGYQANHHMCVATAETIKTFHKLGLKGKIGPAVSFSMIHPASSNPDDVLAS
CCCCHHHEEECCCCCCCEEEEEHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCHHHHHC
QDAMLVKHNYLLDLHCNGEYRAPLWQYLLDRDFAPKIEDGDMQLMKENPPTMIGVNYYFS
CCCEEEEECEEEEEEECCCCCCHHHHHHHCCCCCCCCCCCCHHEEECCCCCEEEEEEEEC
ETVKAFPVSEEFPLGYQKESLLPEAEAGVFQVIKNNELTATDWGWEIDPLGLRLTLRELH
CCHHCCCCCCCCCCCCCHHHCCCCCCCCCEEEEECCCEEECCCCEEECCCCEEEEHHHHH
ERYHLPLIITENGMGAYDKLEAGDVVNDDYRISYLREHIKQTKLAINDGVTVLGYCSWSF
HHHCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHEEECCCCEEEEEECHHH
MDIVSGRNGIDKRYGFVYINRENFDLKDMRRIKKKSFYWYQKVITSNGETLS
HHHHCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MEFRKNKAFPTDFLWGASTSSFQVEGAWQEDGKGLSVIDVMKKNPKITDFTVAVDHYHRM
CCCCCCCCCCCCEEECCCCCCEEEEECHHCCCCCCEEEEHHHCCCCEEEEEEEHHHHHHH
KEDVALMAELGLKVYRFSIAWTRIFPSGRGDINQKGVDFYNDLIDELCKYGIEPLVTIYH
HHHHHHHHHHCCEEEEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEE
FDYPQSLVEEYGGWMSRKSVEDYRAYAEFLFQTYGDRVKYWLTINEQDHVVRIPSRLGLT
CCCHHHHHHHHCCHHCCCCHHHHHHHHHHHHHHCCCEEEEEEEECCCCCEEECHHHCCCC
GENKYEQLKLGYQANHHMCVATAETIKTFHKLGLKGKIGPAVSFSMIHPASSNPDDVLAS
CCCCHHHEEECCCCCCCEEEEEHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCHHHHHC
QDAMLVKHNYLLDLHCNGEYRAPLWQYLLDRDFAPKIEDGDMQLMKENPPTMIGVNYYFS
CCCEEEEECEEEEEEECCCCCCHHHHHHHCCCCCCCCCCCCHHEEECCCCCEEEEEEEEC
ETVKAFPVSEEFPLGYQKESLLPEAEAGVFQVIKNNELTATDWGWEIDPLGLRLTLRELH
CCHHCCCCCCCCCCCCCHHHCCCCCCCCCEEEEECCCEEECCCCEEECCCCEEEEHHHHH
ERYHLPLIITENGMGAYDKLEAGDVVNDDYRISYLREHIKQTKLAINDGVTVLGYCSWSF
HHHCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHEEECCCCEEEEEECHHH
MDIVSGRNGIDKRYGFVYINRENFDLKDMRRIKKKSFYWYQKVITSNGETLS
HHHHCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7704255; 8969502; 9384377; 2841296 [H]