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The map label for this gene is xylB [H]

Identifier: 116871664

GI number: 116871664

Start: 262902

End: 264392

Strand: Direct

Name: xylB [H]

Synonym: lwe0244

Alternate gene names: 116871664

Gene position: 262902-264392 (Clockwise)

Preceding gene: 116871663

Following gene: 116871667

Centisome position: 9.34

GC content: 41.11

Gene sequence:

>1491_bases
ATGGCTTATGTGTTAGGGTTAGATTTAGGAACAAGCGCACTAAAAGCAGTGTTGATGACTGAAATAGGCGAATGGATAGC
CGAGGCATCAAGTGATTATCCATTAATTAGTGAAAAAAAAGGATATAGCGAGCAAAATCCGGCTGAGTGGGTTAAAGCGT
TACATGTGGTTTTTGAGGTGCTACACCAAAAAGTCCCAGATTTAAAAGAAAAACTTGCTGGAATTAGCTTTTCAGGTCAA
ATGCACAGTTTAGTCGTAATGGATAGCGAGATGAAAGTGATCCGTCCTGCAATTTTATGGAATGATGTGCGCACAACGAA
AGCATGTCAATTTATTCGAGAGACAATGCCGGATATTCAGATGATTACGCGAAATCCAGTTTTAGAAGGCTTTACGCTTC
CAAAATTAGTTTGGATTATGCAAAATGAACCAGAAACTTGGCGACAGGCGGCGCATTTTTGTTTGCCAAAAGATTATTTA
GCTTATATTTTAACAGGAGAGTTATGTACCGATTACTCGGATGCAGCAGGAACGCTACTTTTGAATGTCACAAAGAAAGT
TTATTCAGATGAAATTTTAGACACGTTCCAAATTCCTAAAAAGGCACTTCCAAAACTTGTTTCATCCACGACGTGTATTG
GAGTAGTAACGGTTGAAGCGGCGCAAAAGATTGGGATTAAAACGGACGTCAAAGTGTTTATGGGCGGGGCAGATAATGCA
GTAGCCGCAATTGGGGCAGGAATTACTCGACCAGGTCTTGCTCTTTCAAGTATTGGAACGAGTGGCGTCTTCTTAAATTT
CGAATCAAACTTTTTGGAAGCCGACGCAGCACCACTACATTTCTTTAACCATATAGAGGAAGAGGCTTTTTATTCCATGG
GTGTCACGCTTTCGGCGGGCAATAGCTTGAATTGGTTTAAACGGGAATTTGCACCAGAAGAAAGTTTTGACGAGCTTTTT
TCTAGTGCGAGCCGTATTCCAGTTGGCGCGGAGGGGTTACTTTTTACCCCGTATATAAACGGCGAGCGGACGCCATATAC
AGATAGCGAAATTCGTGGCTCTTTTATTGGTATTGATAGCAGACATACGCGAAGTCACTTTATGCGAGCCGTTTTAGAAG
GTATTACGTTTTCTTTGCGAGATACTTTTGAGCTTTTAAAAATAGCAGGACGTGATGCGGCGGAGATCATTGCAGTTGGC
GGCGGGGCCAGAAACCCTTTATGGCTTCAAATACAGGCAGACATTTATAATCGAAATGTACGAACGTTGACGAATGAACA
AGGGCCGGGTGTTGGTGCAGCAATGATTGCGGCTACAGGATTAAACTATTTTTCAAATTTAAATGATTGTGCGGCGCTTT
TCGTCAACTATAGCGATAAAATTTATATACCAAACGAACAAAATGTGCGTGCATACGAAAAAATGTACACGATTTATCGT
GAAATTTACAAGTCAACTAAACTACTTTCAATGAGTCTAGCCAAGCTATAA

Upstream 100 bases:

>100_bases
CTGAATATGCGTTAGCACATGATTCTATCCAAAACGAATCTAGCCATATCGAATATGTGAAGTCACGCTTGAACGATTAT
TTAGTATAAAGGAGAAAAAA

Downstream 100 bases:

>100_bases
AGCAAAAAACGCCCATTTTTTCTCTTTTAAAATGTGGAAATGTATTGGTCATTTCTCATGGTATGATGTGAACATTACTC
TTATATCTTCTTGGTGGATA

Product: xylulose kinase

Products: NA

Alternate protein names: Xylulokinase [H]

Number of amino acids: Translated: 496; Mature: 495

Protein sequence:

>496_residues
MAYVLGLDLGTSALKAVLMTEIGEWIAEASSDYPLISEKKGYSEQNPAEWVKALHVVFEVLHQKVPDLKEKLAGISFSGQ
MHSLVVMDSEMKVIRPAILWNDVRTTKACQFIRETMPDIQMITRNPVLEGFTLPKLVWIMQNEPETWRQAAHFCLPKDYL
AYILTGELCTDYSDAAGTLLLNVTKKVYSDEILDTFQIPKKALPKLVSSTTCIGVVTVEAAQKIGIKTDVKVFMGGADNA
VAAIGAGITRPGLALSSIGTSGVFLNFESNFLEADAAPLHFFNHIEEEAFYSMGVTLSAGNSLNWFKREFAPEESFDELF
SSASRIPVGAEGLLFTPYINGERTPYTDSEIRGSFIGIDSRHTRSHFMRAVLEGITFSLRDTFELLKIAGRDAAEIIAVG
GGARNPLWLQIQADIYNRNVRTLTNEQGPGVGAAMIAATGLNYFSNLNDCAALFVNYSDKIYIPNEQNVRAYEKMYTIYR
EIYKSTKLLSMSLAKL

Sequences:

>Translated_496_residues
MAYVLGLDLGTSALKAVLMTEIGEWIAEASSDYPLISEKKGYSEQNPAEWVKALHVVFEVLHQKVPDLKEKLAGISFSGQ
MHSLVVMDSEMKVIRPAILWNDVRTTKACQFIRETMPDIQMITRNPVLEGFTLPKLVWIMQNEPETWRQAAHFCLPKDYL
AYILTGELCTDYSDAAGTLLLNVTKKVYSDEILDTFQIPKKALPKLVSSTTCIGVVTVEAAQKIGIKTDVKVFMGGADNA
VAAIGAGITRPGLALSSIGTSGVFLNFESNFLEADAAPLHFFNHIEEEAFYSMGVTLSAGNSLNWFKREFAPEESFDELF
SSASRIPVGAEGLLFTPYINGERTPYTDSEIRGSFIGIDSRHTRSHFMRAVLEGITFSLRDTFELLKIAGRDAAEIIAVG
GGARNPLWLQIQADIYNRNVRTLTNEQGPGVGAAMIAATGLNYFSNLNDCAALFVNYSDKIYIPNEQNVRAYEKMYTIYR
EIYKSTKLLSMSLAKL
>Mature_495_residues
AYVLGLDLGTSALKAVLMTEIGEWIAEASSDYPLISEKKGYSEQNPAEWVKALHVVFEVLHQKVPDLKEKLAGISFSGQM
HSLVVMDSEMKVIRPAILWNDVRTTKACQFIRETMPDIQMITRNPVLEGFTLPKLVWIMQNEPETWRQAAHFCLPKDYLA
YILTGELCTDYSDAAGTLLLNVTKKVYSDEILDTFQIPKKALPKLVSSTTCIGVVTVEAAQKIGIKTDVKVFMGGADNAV
AAIGAGITRPGLALSSIGTSGVFLNFESNFLEADAAPLHFFNHIEEEAFYSMGVTLSAGNSLNWFKREFAPEESFDELFS
SASRIPVGAEGLLFTPYINGERTPYTDSEIRGSFIGIDSRHTRSHFMRAVLEGITFSLRDTFELLKIAGRDAAEIIAVGG
GARNPLWLQIQADIYNRNVRTLTNEQGPGVGAAMIAATGLNYFSNLNDCAALFVNYSDKIYIPNEQNVRAYEKMYTIYRE
IYKSTKLLSMSLAKL

Specific function: Unknown

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI42794763, Length=440, Percent_Identity=23.6363636363636, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI41393575, Length=417, Percent_Identity=24.220623501199, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI4504007, Length=440, Percent_Identity=23.4090909090909, Blast_Score=103, Evalue=5e-22,
Organism=Homo sapiens, GI189409120, Length=440, Percent_Identity=23.4090909090909, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI88196792, Length=513, Percent_Identity=22.6120857699805, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI18860918, Length=426, Percent_Identity=23.2394366197183, Blast_Score=79, Evalue=9e-15,
Organism=Escherichia coli, GI1789987, Length=484, Percent_Identity=33.2644628099174, Blast_Score=280, Evalue=1e-76,
Organism=Escherichia coli, GI1790005, Length=484, Percent_Identity=25.6198347107438, Blast_Score=160, Evalue=2e-40,
Organism=Escherichia coli, GI1789168, Length=474, Percent_Identity=25.7383966244726, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1790361, Length=473, Percent_Identity=26.215644820296, Blast_Score=130, Evalue=3e-31,
Organism=Escherichia coli, GI1787789, Length=508, Percent_Identity=22.8346456692913, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI1789138, Length=508, Percent_Identity=22.244094488189, Blast_Score=108, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI17535599, Length=444, Percent_Identity=24.5495495495495, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17554530, Length=480, Percent_Identity=22.9166666666667, Blast_Score=92, Evalue=8e-19,
Organism=Saccharomyces cerevisiae, GI6321755, Length=425, Percent_Identity=24.7058823529412, Blast_Score=85, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6321633, Length=313, Percent_Identity=25.5591054313099, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI17864214, Length=463, Percent_Identity=26.133909287257, Blast_Score=120, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24654573, Length=392, Percent_Identity=27.2959183673469, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24655555, Length=441, Percent_Identity=25.3968253968254, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24655560, Length=441, Percent_Identity=25.3968253968254, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24655570, Length=441, Percent_Identity=25.3968253968254, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24655574, Length=441, Percent_Identity=25.3968253968254, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24655565, Length=441, Percent_Identity=25.3968253968254, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI21356607, Length=492, Percent_Identity=26.6260162601626, Blast_Score=89, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006000 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.17 [H]

Molecular weight: Translated: 54934; Mature: 54802

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: PS00933 FGGY_KINASES_1 ; PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYVLGLDLGTSALKAVLMTEIGEWIAEASSDYPLISEKKGYSEQNPAEWVKALHVVFEV
CEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
LHQKVPDLKEKLAGISFSGQMHSLVVMDSEMKVIRPAILWNDVRTTKACQFIRETMPDIQ
HHHHCCHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCE
MITRNPVLEGFTLPKLVWIMQNEPETWRQAAHFCLPKDYLAYILTGELCTDYSDAAGTLL
EHHCCCCCCCCCCCCEEEEECCCCHHHHHHHHHCCCHHHHHHHHCCHHHCCCCCCCCHHH
LNVTKKVYSDEILDTFQIPKKALPKLVSSTTCIGVVTVEAAQKIGIKTDVKVFMGGADNA
HHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEEEEEEHHHHCCCCCCEEEEECCCCCH
VAAIGAGITRPGLALSSIGTSGVFLNFESNFLEADAAPLHFFNHIEEEAFYSMGVTLSAG
HHHHCCCCCCCCCCHHCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCEEEECC
NSLNWFKREFAPEESFDELFSSASRIPVGAEGLLFTPYINGERTPYTDSEIRGSFIGIDS
CCCHHHHHHCCCCCHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCCHHHCCCEECCCC
RHTRSHFMRAVLEGITFSLRDTFELLKIAGRDAAEIIAVGGGARNPLWLQIQADIYNRNV
CHHHHHHHHHHHHHCEEHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEEEECCCCCCC
RTLTNEQGPGVGAAMIAATGLNYFSNLNDCAALFVNYSDKIYIPNEQNVRAYEKMYTIYR
CEECCCCCCCCHHHHHHHHHHHHHHCCHHHHHHEEECCCEEEECCCCCHHHHHHHHHHHH
EIYKSTKLLSMSLAKL
HHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AYVLGLDLGTSALKAVLMTEIGEWIAEASSDYPLISEKKGYSEQNPAEWVKALHVVFEV
EEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
LHQKVPDLKEKLAGISFSGQMHSLVVMDSEMKVIRPAILWNDVRTTKACQFIRETMPDIQ
HHHHCCHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCE
MITRNPVLEGFTLPKLVWIMQNEPETWRQAAHFCLPKDYLAYILTGELCTDYSDAAGTLL
EHHCCCCCCCCCCCCEEEEECCCCHHHHHHHHHCCCHHHHHHHHCCHHHCCCCCCCCHHH
LNVTKKVYSDEILDTFQIPKKALPKLVSSTTCIGVVTVEAAQKIGIKTDVKVFMGGADNA
HHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEEEEEEHHHHCCCCCCEEEEECCCCCH
VAAIGAGITRPGLALSSIGTSGVFLNFESNFLEADAAPLHFFNHIEEEAFYSMGVTLSAG
HHHHCCCCCCCCCCHHCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCEEEECC
NSLNWFKREFAPEESFDELFSSASRIPVGAEGLLFTPYINGERTPYTDSEIRGSFIGIDS
CCCHHHHHHCCCCCHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCCHHHCCCEECCCC
RHTRSHFMRAVLEGITFSLRDTFELLKIAGRDAAEIIAVGGGARNPLWLQIQADIYNRNV
CHHHHHHHHHHHHHCEEHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEEEECCCCCCC
RTLTNEQGPGVGAAMIAATGLNYFSNLNDCAALFVNYSDKIYIPNEQNVRAYEKMYTIYR
CEECCCCCCCCHHHHHHHHHHHHHHCCHHHHHHEEECCCEEEECCCCCHHHHHHHHHHHH
EIYKSTKLLSMSLAKL
HHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 2994009 [H]