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The map label for this gene is macB [H]

Identifier: 116871584

GI number: 116871584

Start: 163347

End: 164558

Strand: Direct

Name: macB [H]

Synonym: lwe0164

Alternate gene names: 116871584

Gene position: 163347-164558 (Clockwise)

Preceding gene: 116871583

Following gene: 116871585

Centisome position: 5.8

GC content: 37.79

Gene sequence:

>1212_bases
ATGAATGTTCTCCAAAGTATGAAAATGGCATGGAAACAATTAAAAGCTAGTAAACTGAGATCTTTTCTAACGATGCTTGG
TATTATTATCGGTGTCGCATCCGTTATTCTTTTAGTTTCGCTCGGAAATGGTGTAACCAAAGAAGTTGATGAGCAAATGG
GTGACTTAGGATCCAATTTAATCACAGTAGTAAATAGTTCTGTGAATCCAAATGATAAATATACGTATGATGAAGTAATG
AAATATCAAAATATTGATGGTGTTAAAAGCGTTTCACCAGAACTTTCAGGACAAGTGAATGCTACATTTGATTATAAAAA
CTCCAGCAATAAAGTTATAGGAACGAACGACCAGTATAAAGCAGCCCGTAGCCTCGAAATGAAGGATGGCCGCTTCTTGC
TACCAATTGATACGGAATATGGTCAGAAGGTAGCTGTAATCGGCTCTACGGTAGCTAGTGATTTGTTTGGCTTCGGTAAC
CCCATTGGCGAAACAATTAGATTAAACGGCATGCCATACAAAGTAGTAGGTGTTTTAAAAGAAAAAGGTGCTTCGATGAT
GGGATCAAGTGATGATCAAATCTTCATTCCGATTTCTTCTGCTCAAAGACTACTAAAAGATACAAATGTACGAACTATTT
ATGTTGAAACAAAATCTGCTGAGGATGTTGATTTCGTGGTTAATACGTTGGAATCCCGCCTTGCTATAAAATTTGGTGAC
GAGAAAGAGCAAAAAGAGAAAGCTGCTTCCTCGGCGCAAATGGGACCATCATATCAAGTTATTAATCAACAAGAAATCCT
CAATGCGTTTAATACAATCAGTACAACCTTAACAACTGCGCTTGGTGCAATTGCTGCCATTTCGCTTGTAGTAGGTGGTA
TTGGAATTATGAATATTATGTTAGTTTCTGTCAGTGAAAGAACGAGAGAAATTGGTATCAGAAAAGCGCTTGGAGCTAAA
AAACGTGCTATTTTACTGCAATTCCTAATAGAATCTATCGTTATTAGTGTATGCGGGGGACTGATTGGAATAATTATTGG
AGTCTCAGGAGCGCTTATCTTTGGCTCTGTTGCGGGTATATCATCAGGAATAACCGCGGGAACAATTATCTTTTCCTTTG
TCTTCTCCTTATGTATTGGAGTGATATTTGGTATCGCACCTGCTAATAAGGCATCGAAATTAAGACCAATTGATGCTTTG
AGGTCAGAATAA

Upstream 100 bases:

>100_bases
CAATTGTTATGATTACACATGATCCGACAATTGCCTCTTATGGAACAAGAAGCATTCGAATTCAAGATGGTAAATTATTC
CATGAGGAGGCGACAAAAGC

Downstream 100 bases:

>100_bases
CTAAAAAGAAATCCAGAATTTTGTTCTCTGGATTTCTTTTTTTCTAAACGGAAATACTAAAAAAGATGTCTTGTCATCTA
TATTTAATGTTTTTGTCATA

Product: ABC transporter, permease protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 403; Mature: 403

Protein sequence:

>403_residues
MNVLQSMKMAWKQLKASKLRSFLTMLGIIIGVASVILLVSLGNGVTKEVDEQMGDLGSNLITVVNSSVNPNDKYTYDEVM
KYQNIDGVKSVSPELSGQVNATFDYKNSSNKVIGTNDQYKAARSLEMKDGRFLLPIDTEYGQKVAVIGSTVASDLFGFGN
PIGETIRLNGMPYKVVGVLKEKGASMMGSSDDQIFIPISSAQRLLKDTNVRTIYVETKSAEDVDFVVNTLESRLAIKFGD
EKEQKEKAASSAQMGPSYQVINQQEILNAFNTISTTLTTALGAIAAISLVVGGIGIMNIMLVSVSERTREIGIRKALGAK
KRAILLQFLIESIVISVCGGLIGIIIGVSGALIFGSVAGISSGITAGTIIFSFVFSLCIGVIFGIAPANKASKLRPIDAL
RSE

Sequences:

>Translated_403_residues
MNVLQSMKMAWKQLKASKLRSFLTMLGIIIGVASVILLVSLGNGVTKEVDEQMGDLGSNLITVVNSSVNPNDKYTYDEVM
KYQNIDGVKSVSPELSGQVNATFDYKNSSNKVIGTNDQYKAARSLEMKDGRFLLPIDTEYGQKVAVIGSTVASDLFGFGN
PIGETIRLNGMPYKVVGVLKEKGASMMGSSDDQIFIPISSAQRLLKDTNVRTIYVETKSAEDVDFVVNTLESRLAIKFGD
EKEQKEKAASSAQMGPSYQVINQQEILNAFNTISTTLTTALGAIAAISLVVGGIGIMNIMLVSVSERTREIGIRKALGAK
KRAILLQFLIESIVISVCGGLIGIIIGVSGALIFGSVAGISSGITAGTIIFSFVFSLCIGVIFGIAPANKASKLRPIDAL
RSE
>Mature_403_residues
MNVLQSMKMAWKQLKASKLRSFLTMLGIIIGVASVILLVSLGNGVTKEVDEQMGDLGSNLITVVNSSVNPNDKYTYDEVM
KYQNIDGVKSVSPELSGQVNATFDYKNSSNKVIGTNDQYKAARSLEMKDGRFLLPIDTEYGQKVAVIGSTVASDLFGFGN
PIGETIRLNGMPYKVVGVLKEKGASMMGSSDDQIFIPISSAQRLLKDTNVRTIYVETKSAEDVDFVVNTLESRLAIKFGD
EKEQKEKAASSAQMGPSYQVINQQEILNAFNTISTTLTTALGAIAAISLVVGGIGIMNIMLVSVSERTREIGIRKALGAK
KRAILLQFLIESIVISVCGGLIGIIIGVSGALIFGSVAGISSGITAGTIIFSFVFSLCIGVIFGIAPANKASKLRPIDAL
RSE

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=409, Percent_Identity=31.5403422982885, Blast_Score=178, Evalue=4e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 43074; Mature: 43074

Theoretical pI: Translated: 9.17; Mature: 9.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVLQSMKMAWKQLKASKLRSFLTMLGIIIGVASVILLVSLGNGVTKEVDEQMGDLGSNL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHH
ITVVNSSVNPNDKYTYDEVMKYQNIDGVKSVSPELSGQVNATFDYKNSSNKVIGTNDQYK
EEHCCCCCCCCCCCCHHHHHHHCCCCCHHHCCCCCCCCEEEEEEECCCCCCEECCCCHHH
AARSLEMKDGRFLLPIDTEYGQKVAVIGSTVASDLFGFGNPIGETIRLNGMPYKVVGVLK
HHHCCEECCCCEEEEECCCCCCEEEEHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHH
EKGASMMGSSDDQIFIPISSAQRLLKDTNVRTIYVETKSAEDVDFVVNTLESRLAIKFGD
HCCCHHCCCCCCEEEEEHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHEEEEECC
EKEQKEKAASSAQMGPSYQVINQQEILNAFNTISTTLTTALGAIAAISLVVGGIGIMNIM
CHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVSVSERTREIGIRKALGAKKRAILLQFLIESIVISVCGGLIGIIIGVSGALIFGSVAGI
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SSGITAGTIIFSFVFSLCIGVIFGIAPANKASKLRPIDALRSE
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHCC
>Mature Secondary Structure
MNVLQSMKMAWKQLKASKLRSFLTMLGIIIGVASVILLVSLGNGVTKEVDEQMGDLGSNL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHH
ITVVNSSVNPNDKYTYDEVMKYQNIDGVKSVSPELSGQVNATFDYKNSSNKVIGTNDQYK
EEHCCCCCCCCCCCCHHHHHHHCCCCCHHHCCCCCCCCEEEEEEECCCCCCEECCCCHHH
AARSLEMKDGRFLLPIDTEYGQKVAVIGSTVASDLFGFGNPIGETIRLNGMPYKVVGVLK
HHHCCEECCCCEEEEECCCCCCEEEEHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHH
EKGASMMGSSDDQIFIPISSAQRLLKDTNVRTIYVETKSAEDVDFVVNTLESRLAIKFGD
HCCCHHCCCCCCEEEEEHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHEEEEECC
EKEQKEKAASSAQMGPSYQVINQQEILNAFNTISTTLTTALGAIAAISLVVGGIGIMNIM
CHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVSVSERTREIGIRKALGAKKRAILLQFLIESIVISVCGGLIGIIIGVSGALIFGSVAGI
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SSGITAGTIIFSFVFSLCIGVIFGIAPANKASKLRPIDALRSE
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA