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The map label for this gene is appC [H]

Identifier: 116871539

GI number: 116871539

Start: 121081

End: 121977

Strand: Direct

Name: appC [H]

Synonym: lwe0119

Alternate gene names: 116871539

Gene position: 121081-121977 (Clockwise)

Preceding gene: 116871538

Following gene: 116871540

Centisome position: 4.3

GC content: 42.03

Gene sequence:

>897_bases
ATGATGCGATTAGATTTTTCAAAAAAAACAATGCAAGATTTCGAGCGGGATGCAGAAGTAGTTCATGCGACGAGAGAGCG
GAGTTTTTGGCGTTTTATGCTCGCTGACCGACGTGCTGTTTTTGCGACGAGTGTGCTGATACTTATTACAGTTGCTTGTA
TTTTTGCGTTCCTTTCCCCTTATGATCCTAATGCACTCTCGGTTCAGGACAAATTAATGCCGCCCAATTTGGCGCACTGG
TTTGGAACGGATGACCATGGTCGAGATTACTTGACGCGCGTTTTGTATGGTGGCCGAGTTTCACTACTTGTTGGGGTATT
TGCGATGATGATTGCCGTTGTCGTTGGTACACTAGCTGGTACTGTTAGTGGTTATTTTGGTGGTTTTATTGATAATATGG
TGATGCGTTTTCTAGATATTTTCATGTCGATTCCTTCATTTTTCTTACTAATGATTTTAAATGCGTACTTAAAACCGGGG
ATTTCGAACATTATTATCATCATTGGATTGCTTTCATGGATGGAAGTAGCGCGGATAGTCCGAGCAGAAACACTGACGTT
AAAAGAACGTGAATTCATTTTGTATTCCAAATCATCTGGTGGTGGATTTTTCCACATAATGTTCAAACACATCATTCCAA
ATGCGATGCCATCTATCGTCGTTGCAGCTTCATTAAACGTCGCTACAGCCATTTTAACCGAGTCGGCACTAAGTTTCCTT
GGACTCGGAGTTCAACAACCTAACGCTTCATGGGGTAGCATGCTGAACAATGCGCAAGGCTACGTCGGTGAAGCAACATA
CTTGGCACTTTTCCCAGGACTATTAATTTTGATGACCATTCTTTCATTTAATGTCCTTGGCGATGTACTAAGAAAAGGCC
TATCTCGCAGATACTAA

Upstream 100 bases:

>100_bases
ACGCTTTTTTCAGCGCTATTATTAATTATCGGCAACTTGCTAGCCGATTTAGCTTATATGATTGTCGATCCACGGATTAG
GGAAATGGGGTGAGGAATTC

Downstream 100 bases:

>100_bases
TACAAAACACTTTGACTTTCTCCGTCAAAGTGTTTTTTTGCGCAAAATATTCCATCAGAAGCCAACTTATTCACTTCATC
TAGCTCATGAAGCCAATTTT

Product: dipeptide/oligopeptide ABC transporter, permease protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MMRLDFSKKTMQDFERDAEVVHATRERSFWRFMLADRRAVFATSVLILITVACIFAFLSPYDPNALSVQDKLMPPNLAHW
FGTDDHGRDYLTRVLYGGRVSLLVGVFAMMIAVVVGTLAGTVSGYFGGFIDNMVMRFLDIFMSIPSFFLLMILNAYLKPG
ISNIIIIIGLLSWMEVARIVRAETLTLKEREFILYSKSSGGGFFHIMFKHIIPNAMPSIVVAASLNVATAILTESALSFL
GLGVQQPNASWGSMLNNAQGYVGEATYLALFPGLLILMTILSFNVLGDVLRKGLSRRY

Sequences:

>Translated_298_residues
MMRLDFSKKTMQDFERDAEVVHATRERSFWRFMLADRRAVFATSVLILITVACIFAFLSPYDPNALSVQDKLMPPNLAHW
FGTDDHGRDYLTRVLYGGRVSLLVGVFAMMIAVVVGTLAGTVSGYFGGFIDNMVMRFLDIFMSIPSFFLLMILNAYLKPG
ISNIIIIIGLLSWMEVARIVRAETLTLKEREFILYSKSSGGGFFHIMFKHIIPNAMPSIVVAASLNVATAILTESALSFL
GLGVQQPNASWGSMLNNAQGYVGEATYLALFPGLLILMTILSFNVLGDVLRKGLSRRY
>Mature_298_residues
MMRLDFSKKTMQDFERDAEVVHATRERSFWRFMLADRRAVFATSVLILITVACIFAFLSPYDPNALSVQDKLMPPNLAHW
FGTDDHGRDYLTRVLYGGRVSLLVGVFAMMIAVVVGTLAGTVSGYFGGFIDNMVMRFLDIFMSIPSFFLLMILNAYLKPG
ISNIIIIIGLLSWMEVARIVRAETLTLKEREFILYSKSSGGGFFHIMFKHIIPNAMPSIVVAASLNVATAILTESALSFL
GLGVQQPNASWGSMLNNAQGYVGEATYLALFPGLLILMTILSFNVLGDVLRKGLSRRY

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=276, Percent_Identity=40.2173913043478, Blast_Score=207, Evalue=6e-55,
Organism=Escherichia coli, GI1787760, Length=259, Percent_Identity=38.2239382239382, Blast_Score=201, Evalue=4e-53,
Organism=Escherichia coli, GI1787498, Length=308, Percent_Identity=40.5844155844156, Blast_Score=177, Evalue=1e-45,
Organism=Escherichia coli, GI1789889, Length=235, Percent_Identity=36.5957446808511, Blast_Score=174, Evalue=7e-45,
Organism=Escherichia coli, GI1789964, Length=285, Percent_Identity=36.4912280701754, Blast_Score=169, Evalue=3e-43,
Organism=Escherichia coli, GI1788505, Length=224, Percent_Identity=32.1428571428571, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1787549, Length=275, Percent_Identity=27.6363636363636, Blast_Score=120, Evalue=9e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 33151; Mature: 33151

Theoretical pI: Translated: 9.50; Mature: 9.50

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMRLDFSKKTMQDFERDAEVVHATRERSFWRFMLADRRAVFATSVLILITVACIFAFLSP
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
YDPNALSVQDKLMPPNLAHWFGTDDHGRDYLTRVLYGGRVSLLVGVFAMMIAVVVGTLAG
CCCCCCCCHHHCCCCCHHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
TVSGYFGGFIDNMVMRFLDIFMSIPSFFLLMILNAYLKPGISNIIIIIGLLSWMEVARIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
RAETLTLKEREFILYSKSSGGGFFHIMFKHIIPNAMPSIVVAASLNVATAILTESALSFL
HHHHHEEECCEEEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GLGVQQPNASWGSMLNNAQGYVGEATYLALFPGLLILMTILSFNVLGDVLRKGLSRRY
HCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MMRLDFSKKTMQDFERDAEVVHATRERSFWRFMLADRRAVFATSVLILITVACIFAFLSP
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
YDPNALSVQDKLMPPNLAHWFGTDDHGRDYLTRVLYGGRVSLLVGVFAMMIAVVVGTLAG
CCCCCCCCHHHCCCCCHHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
TVSGYFGGFIDNMVMRFLDIFMSIPSFFLLMILNAYLKPGISNIIIIIGLLSWMEVARIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
RAETLTLKEREFILYSKSSGGGFFHIMFKHIIPNAMPSIVVAASLNVATAILTESALSFL
HHHHHEEECCEEEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GLGVQQPNASWGSMLNNAQGYVGEATYLALFPGLLILMTILSFNVLGDVLRKGLSRRY
HCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]