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The map label for this gene is atoC [H]

Identifier: 116691138

GI number: 116691138

Start: 3434752

End: 3435423

Strand: Reverse

Name: atoC [H]

Synonym: Bcen2424_3120

Alternate gene names: 116691138

Gene position: 3435423-3434752 (Counterclockwise)

Preceding gene: 116691139

Following gene: 116691137

Centisome position: 98.61

GC content: 69.05

Gene sequence:

>672_bases
ATGGGCATCCGGGAATTGCTCTCGGAGATCCTCAGCGATGAAGGACATGTCGTCGAGGCGGCGGAGAACGCGCAGGCCGC
GCGGGAATACCGGCTGAATCAGGCGCCCGATCTCGTGCTGCTCGATATCTGGATGCCCGATACCGACGGCGTCACGCTGC
TCAAGGAATGGGCGGCGCAGGGGCTGCTGACGATGCCCGTGATCATGATGTCCGGGCACGCGACGATCGATACGGCCGTC
GAGGCGACCAAGATCGGCGCGCTCGATTTCCTCGAAAAGCCGATCGCGCTGCAGAAGCTGCTGAAGTCGGTCGAGCACGG
TCTCGCCCGCGGCGCGGCGCCGGTGTCCGCGAACGCGGCGGCGAAGGCGGGCGGCGGGCAGGCCGCGGGGCCGGCGGCGG
TCGCGTCCGCGGCGGCGCTGCCGACGCTCGGCGACGACATGGCGTCGGCGCTCGGCCTCGCGGGCCAGACGGCGGCGATC
CCGTTCGACATTCCGTTGCGCGAAGCGCGCGATGCGTTCGAGCGCGCGTACTTCGAGTATCACCTCGCGCGCGAGAACGG
CAGCATGACGCGCGTCGCGGAGAAGACGGGCCTCGAGCGCACGCACCTGTATCGCAAGCTCAAGCAGCTCGGCGTCGAGC
TCGGCAAGAAGCCGTCCGAAGGTGCGCTGTAA

Upstream 100 bases:

>100_bases
CGAACCGGGTGCACAGGACGGGACGACTCCCGCCAAGACAAAAGCAAGTGAGCAGACAAAGGCAGCGTAAATGGCAACCA
TCCTGGTGGTAGATGATGAA

Downstream 100 bases:

>100_bases
AATATTTTGCGAAAGCACTTGCCCGGGGGCGGATAGCTCGATATACTTTCATTCTTCGTTGGCCCGGTAGCTCAGTTGGT
AGAGCAGCGGATTGAAAATC

Product: response regulator receiver protein

Products: NA

Alternate protein names: Ornithine decarboxylase antizyme; Ornithine/arginine decarboxylase inhibitor [H]

Number of amino acids: Translated: 223; Mature: 222

Protein sequence:

>223_residues
MGIRELLSEILSDEGHVVEAAENAQAAREYRLNQAPDLVLLDIWMPDTDGVTLLKEWAAQGLLTMPVIMMSGHATIDTAV
EATKIGALDFLEKPIALQKLLKSVEHGLARGAAPVSANAAAKAGGGQAAGPAAVASAAALPTLGDDMASALGLAGQTAAI
PFDIPLREARDAFERAYFEYHLARENGSMTRVAEKTGLERTHLYRKLKQLGVELGKKPSEGAL

Sequences:

>Translated_223_residues
MGIRELLSEILSDEGHVVEAAENAQAAREYRLNQAPDLVLLDIWMPDTDGVTLLKEWAAQGLLTMPVIMMSGHATIDTAV
EATKIGALDFLEKPIALQKLLKSVEHGLARGAAPVSANAAAKAGGGQAAGPAAVASAAALPTLGDDMASALGLAGQTAAI
PFDIPLREARDAFERAYFEYHLARENGSMTRVAEKTGLERTHLYRKLKQLGVELGKKPSEGAL
>Mature_222_residues
GIRELLSEILSDEGHVVEAAENAQAAREYRLNQAPDLVLLDIWMPDTDGVTLLKEWAAQGLLTMPVIMMSGHATIDTAVE
ATKIGALDFLEKPIALQKLLKSVEHGLARGAAPVSANAAAKAGGGQAAGPAAVASAAALPTLGDDMASALGLAGQTAAIP
FDIPLREARDAFERAYFEYHLARENGSMTRVAEKTGLERTHLYRKLKQLGVELGKKPSEGAL

Specific function: Member of the two-component regulatory system AtoS/AtoC involved in the transcriptional regulation of the ato genes for acetoacetate metabolism. Also an inhibitor of polyamine biosynthesis [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=107, Percent_Identity=37.3831775700935, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1790437, Length=104, Percent_Identity=38.4615384615385, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI1790299, Length=107, Percent_Identity=35.5140186915888, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787375, Length=110, Percent_Identity=26.3636363636364, Blast_Score=63, Evalue=1e-11,
Organism=Escherichia coli, GI1786784, Length=114, Percent_Identity=35.0877192982456, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 23549; Mature: 23418

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGIRELLSEILSDEGHVVEAAENAQAAREYRLNQAPDLVLLDIWMPDTDGVTLLKEWAAQ
CCHHHHHHHHHCCCCCEEECHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHC
GLLTMPVIMMSGHATIDTAVEATKIGALDFLEKPIALQKLLKSVEHGLARGAAPVSANAA
CHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCH
AKAGGGQAAGPAAVASAAALPTLGDDMASALGLAGQTAAIPFDIPLREARDAFERAYFEY
HCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
HLARENGSMTRVAEKTGLERTHLYRKLKQLGVELGKKPSEGAL
HHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
GIRELLSEILSDEGHVVEAAENAQAAREYRLNQAPDLVLLDIWMPDTDGVTLLKEWAAQ
CHHHHHHHHHCCCCCEEECHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHC
GLLTMPVIMMSGHATIDTAVEATKIGALDFLEKPIALQKLLKSVEHGLARGAAPVSANAA
CHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCH
AKAGGGQAAGPAAVASAAALPTLGDDMASALGLAGQTAAIPFDIPLREARDAFERAYFEY
HCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
HLARENGSMTRVAEKTGLERTHLYRKLKQLGVELGKKPSEGAL
HHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 8346225 [H]