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The map label for this gene is 116690982

Identifier: 116690982

GI number: 116690982

Start: 3275787

End: 3276683

Strand: Reverse

Name: 116690982

Synonym: Bcen2424_2964

Alternate gene names: NA

Gene position: 3276683-3275787 (Counterclockwise)

Preceding gene: 116690984

Following gene: 116690980

Centisome position: 94.05

GC content: 69.34

Gene sequence:

>897_bases
ATGTCGTTTGAGGCGTTTGCACCGTTTCGCGTGACGGTGCAGGACACCGACATTTTCGGTGTCAAAGGAGGCACGGGTCC
GCCGCTGCTGTTGCTGCACGGCCATCCGCAGACCCACATGATCTGGCATCGCGTTGCGGCGACGCTCGCGAATCACTTCA
CGGTGATCGCCACCGACCTGCGCGGCTACGGCGCGTCGGGCAGGCCGCCGAGCGACGCGCGGCACACGCCGTATTCGAAA
CGGGCGATGGCGGCGGACCAGGTCGCCGTGATGCGTCATTTCGGCTTCGAGCAGTTCCACGTGTGTGCGCACGATCGCGG
CGCGCGGGTCGCGCACCGGCTCGCGCTCGACCACGCGGACGCCGTCGAGCGGATGATGCTGCTCGACATCGCGCCGACGC
TCGCGATGTACGAGAAAACCGATCGCGCGTTCGCGACCGCGTATTTCCACTGGTTCTTCCTGATCCAGCCCGAGCCGCTG
CCCGAGACGCTGGTGGGCGCGCACACCGATGCGTACATCGAGCGCGTGATGGGCAACCGCTCGGCCGGGCTGGCGCCGTT
CGCGCCCGAGGCGCTCGACGCGTACCGGGCGGCGCTCGCGCAGCCGGGCGCCGTGCATGCGATGTGCGAGGACTACCGCG
CGTCCGCGACGATCGATCTCGAGCACGACCGTGCGGATCTCGAACGCGGCAACAAGGTCGCGTGCCCGCTGCGCGTGCTG
TGGGGCGAGCACGGCGTCGTCGGCCGCTGCTTCGATCCGCTCGACGAATGGCGGCGCGTCGCGCGCGACGTCAGCGGCCG
TGCGCTCGATTGCGGGCACTACATTCCGGAAGAGGCGCCCGCCGCGCTGATCGACGAACTGCTCGCGTTCTTCGAGGCGC
GCGACGCGGCGGCATGA

Upstream 100 bases:

>100_bases
GTGAGTGTTCTCTTTCTACGGTTTCGGGTGCTTGGCCCGCTGTGAAGACGCGTCGTCGCTCCTAAAATAGCCGCCATAAC
AAACCAACGAGAAACAAACC

Downstream 100 bases:

>100_bases
CGGTGCGGGCGCGCGAGCGGCGCGTGCCGCCCGCGGCTCAGGAATGTACGCTTGCCGTCGCGGCTCAGCGGTGTGCGTGG
TCGTCCTCGACGAGCGGCGG

Product: alpha/beta hydrolase fold

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 297

Protein sequence:

>298_residues
MSFEAFAPFRVTVQDTDIFGVKGGTGPPLLLLHGHPQTHMIWHRVAATLANHFTVIATDLRGYGASGRPPSDARHTPYSK
RAMAADQVAVMRHFGFEQFHVCAHDRGARVAHRLALDHADAVERMMLLDIAPTLAMYEKTDRAFATAYFHWFFLIQPEPL
PETLVGAHTDAYIERVMGNRSAGLAPFAPEALDAYRAALAQPGAVHAMCEDYRASATIDLEHDRADLERGNKVACPLRVL
WGEHGVVGRCFDPLDEWRRVARDVSGRALDCGHYIPEEAPAALIDELLAFFEARDAAA

Sequences:

>Translated_298_residues
MSFEAFAPFRVTVQDTDIFGVKGGTGPPLLLLHGHPQTHMIWHRVAATLANHFTVIATDLRGYGASGRPPSDARHTPYSK
RAMAADQVAVMRHFGFEQFHVCAHDRGARVAHRLALDHADAVERMMLLDIAPTLAMYEKTDRAFATAYFHWFFLIQPEPL
PETLVGAHTDAYIERVMGNRSAGLAPFAPEALDAYRAALAQPGAVHAMCEDYRASATIDLEHDRADLERGNKVACPLRVL
WGEHGVVGRCFDPLDEWRRVARDVSGRALDCGHYIPEEAPAALIDELLAFFEARDAAA
>Mature_297_residues
SFEAFAPFRVTVQDTDIFGVKGGTGPPLLLLHGHPQTHMIWHRVAATLANHFTVIATDLRGYGASGRPPSDARHTPYSKR
AMAADQVAVMRHFGFEQFHVCAHDRGARVAHRLALDHADAVERMMLLDIAPTLAMYEKTDRAFATAYFHWFFLIQPEPLP
ETLVGAHTDAYIERVMGNRSAGLAPFAPEALDAYRAALAQPGAVHAMCEDYRASATIDLEHDRADLERGNKVACPLRVLW
GEHGVVGRCFDPLDEWRRVARDVSGRALDCGHYIPEEAPAALIDELLAFFEARDAAA

Specific function: Catalyzes the hydrolytic defluorination of fluoroacetate to produce glycolate. Has low activity towards chloroacetate [H]

COG id: COG0596

COG function: function code R; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. Epoxide hydrolase family [H]

Homologues:

Organism=Homo sapiens, GI218777840, Length=279, Percent_Identity=27.2401433691756, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI13376164, Length=279, Percent_Identity=27.2401433691756, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI218777837, Length=247, Percent_Identity=23.4817813765182, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17554012, Length=221, Percent_Identity=23.9819004524887, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17562298, Length=222, Percent_Identity=23.4234234234234, Blast_Score=71, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.8.1.3 [H]

Molecular weight: Translated: 32948; Mature: 32817

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFEAFAPFRVTVQDTDIFGVKGGTGPPLLLLHGHPQTHMIWHRVAATLANHFTVIATDL
CCCCCCCCEEEEEECCEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHHCEEEEEEEC
RGYGASGRPPSDARHTPYSKRAMAADQVAVMRHFGFEQFHVCAHDRGARVAHRLALDHAD
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHEEEECCCCCHHHHHHHHHHHHH
AVERMMLLDIAPTLAMYEKTDRAFATAYFHWFFLIQPEPLPETLVGAHTDAYIERVMGNR
HHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEECCCCCCHHHHCCHHHHHHHHHHCCC
SAGLAPFAPEALDAYRAALAQPGAVHAMCEDYRASATIDLEHDRADLERGNKVACPLRVL
CCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEECCCHHHHHCCCEEECCCEEE
WGEHGVVGRCFDPLDEWRRVARDVSGRALDCGHYIPEEAPAALIDELLAFFEARDAAA
ECCCCCCCCHHHHHHHHHHHHHHCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SFEAFAPFRVTVQDTDIFGVKGGTGPPLLLLHGHPQTHMIWHRVAATLANHFTVIATDL
CCCCCCCEEEEEECCEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHHCEEEEEEEC
RGYGASGRPPSDARHTPYSKRAMAADQVAVMRHFGFEQFHVCAHDRGARVAHRLALDHAD
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHEEEECCCCCHHHHHHHHHHHHH
AVERMMLLDIAPTLAMYEKTDRAFATAYFHWFFLIQPEPLPETLVGAHTDAYIERVMGNR
HHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEECCCCCCHHHHCCHHHHHHHHHHCCC
SAGLAPFAPEALDAYRAALAQPGAVHAMCEDYRASATIDLEHDRADLERGNKVACPLRVL
CCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEECCCHHHHHCCCEEECCCEEE
WGEHGVVGRCFDPLDEWRRVARDVSGRALDCGHYIPEEAPAALIDELLAFFEARDAAA
ECCCCCCCCHHHHHHHHHHHHHHCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA