Click here to switch to the map view.

The map label for this gene is yjcE [H]

Identifier: 116690957

GI number: 116690957

Start: 3248015

End: 3249682

Strand: Direct

Name: yjcE [H]

Synonym: Bcen2424_2939

Alternate gene names: 116690957

Gene position: 3248015-3249682 (Clockwise)

Preceding gene: 116690952

Following gene: 116690959

Centisome position: 93.23

GC content: 67.93

Gene sequence:

>1668_bases
ATGGAAATCGTTTTCACAGTCCTCATTCTGCTGCTGACCGTCGCACTGTCCGGCGCCGTCACGCGTCTCCTGCCATTGCA
ACTGCCGCTGCCGCTGATGCAGATCGCGTTCGGCGCGATGCTCGCGTGGCCGAAGCTGAACCTGCACGTCACGTTCGATC
CCGAGATCTTCATGCTGCTGTTCATTCCGCCGCTGCTGTTCGCGGACGGCTGGCGGATTCCGAAACGCGAGCTTTATCTG
CAGCGCCGCGCGATCCTGATGCTCGCGTTCGGGCTCGTGTTCATGACGGTACTCGCAGTGGGCTACTTCGCACACTGGCT
GATTCCCGAGTTGCCGCTGCCGATCGCGTTCGCGCTCGCTGCGGTGCTGTCGCCGACCGACGCGGTCGCGCTGTCCGGCA
TCGCCGGCAAGGGCCGCATTCCGCCGCAACTGATGCACATCCTCGAAGGCGAGGCGCTGATGAACGACGCGTCGGGCCTC
GTCGCGCTGAAGTTCGCGATCGCGGCCGCGCTCACCGGCGTGTTCTCGCTGCGCGCCGCGTCGGTCACGTTCGTGATCGT
CGCCGCCGGCGGGCTCGCGACGGGCGCGATCGTGTCGTGGGTATTCAGCGCGCTGTCGACGCGCTTCCTGAATGCCGAGC
AGGAAGGCGATCCGGCCCCGGGCATCGTGATGACGCTGCTGGTGCCGTTCGCCGCCTACCTGTTCGCCGAGCACCTCGAC
CTGTCGGGCGTGCTCGCGGCCGTGTCGGCCGGGATGATGATGAATTACACGAGCTTCTCGCGCAAAAGCACCGTCGCGTC
GCGCGTGCGCGCCGAAAGCACGTGGGCGATGATCGAATTCGTGTTCAACGGCATGGTGTTCATCATGCTCGGGCTGCAGT
TGCCGCACATCATCGGCCGCGCGCTCGTCGACGCGCACCATACGAGCGACGCGCTGGTCGGCCGCATGATCTTCAACGTC
TGCGCGATGATGCTCGCGCTGTACGCGATCCGCTTCCTGTGGGTATGGCTGCTGCGCTGGTTCGCGAGCCGCCGCGCCGC
GCGCCATGGCCTCGCCGGCACGATGGCCGGCGTACGCACGATCGCGGTGATGACGGTCGGCGGCGTGCGCGGCGCGGTCA
CGCTCGCCGGCGTGCTGTCGATTCCGGTCGCGCTGTCCGACGGCGCACCGCTGCCGGGCCGCGACACCGCGATCTTCATC
GCGTCGGCCGTGATCCTCGGCTCACTGATCGTCGGGGTGATCGGCCTGCCGCTGCTGCTGCGCGGCGTGCGCTCGACGCG
CAACCCGCTCGGCAACGAGGAGCGTATCGCACGCTCGGCCGCCGCGCAGGCCGCGATCCGCGCGATCGATTCGTCGCACG
ACGCGATCTCGGCCGATCTCGACGAATCGGGCGCGGCGCGCTGCGCGGACATCTCCGCGCGCGTGATGGATCAATATCGC
CGCCGGCTCGCCGCGCTGGCCGACGACGGCCCCACGCCGCGCGCGCAAGCGCAGCAGGCCGAAACGATGGAGCTGCAGAT
GCGGATCGCGGCCGTGCGCGCGGAACGCTCGGCGCTGTACCGGCTGCGCAGCGACAGCAAGATTTCCGACGAGACGCTGA
CGAAGCTGCTCCGCGAGATCGACCTGTCTGAAACCGCGCTGTCGACGCGCAAGAAAGGCATTGTTTGA

Upstream 100 bases:

>100_bases
CACCATTTCCGTGCGCACGCACCGACCGCTTGAACGCGCCCGTCACGTCGGCACGCTACACTCCGTACGATCGTTTCATT
TCACGTCATTCGCCGTATCG

Downstream 100 bases:

>100_bases
CGGGCCGGCTGCGGCCTGCGCGCAGCCACCGAGGACCATAAAAAACGGCGATGCTCGTGCGAGCGTCGCCGTTTTCACAT
CCACTCACGTTCGCGTTACT

Product: Na+/H+ antiporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 555; Mature: 555

Protein sequence:

>555_residues
MEIVFTVLILLLTVALSGAVTRLLPLQLPLPLMQIAFGAMLAWPKLNLHVTFDPEIFMLLFIPPLLFADGWRIPKRELYL
QRRAILMLAFGLVFMTVLAVGYFAHWLIPELPLPIAFALAAVLSPTDAVALSGIAGKGRIPPQLMHILEGEALMNDASGL
VALKFAIAAALTGVFSLRAASVTFVIVAAGGLATGAIVSWVFSALSTRFLNAEQEGDPAPGIVMTLLVPFAAYLFAEHLD
LSGVLAAVSAGMMMNYTSFSRKSTVASRVRAESTWAMIEFVFNGMVFIMLGLQLPHIIGRALVDAHHTSDALVGRMIFNV
CAMMLALYAIRFLWVWLLRWFASRRAARHGLAGTMAGVRTIAVMTVGGVRGAVTLAGVLSIPVALSDGAPLPGRDTAIFI
ASAVILGSLIVGVIGLPLLLRGVRSTRNPLGNEERIARSAAAQAAIRAIDSSHDAISADLDESGAARCADISARVMDQYR
RRLAALADDGPTPRAQAQQAETMELQMRIAAVRAERSALYRLRSDSKISDETLTKLLREIDLSETALSTRKKGIV

Sequences:

>Translated_555_residues
MEIVFTVLILLLTVALSGAVTRLLPLQLPLPLMQIAFGAMLAWPKLNLHVTFDPEIFMLLFIPPLLFADGWRIPKRELYL
QRRAILMLAFGLVFMTVLAVGYFAHWLIPELPLPIAFALAAVLSPTDAVALSGIAGKGRIPPQLMHILEGEALMNDASGL
VALKFAIAAALTGVFSLRAASVTFVIVAAGGLATGAIVSWVFSALSTRFLNAEQEGDPAPGIVMTLLVPFAAYLFAEHLD
LSGVLAAVSAGMMMNYTSFSRKSTVASRVRAESTWAMIEFVFNGMVFIMLGLQLPHIIGRALVDAHHTSDALVGRMIFNV
CAMMLALYAIRFLWVWLLRWFASRRAARHGLAGTMAGVRTIAVMTVGGVRGAVTLAGVLSIPVALSDGAPLPGRDTAIFI
ASAVILGSLIVGVIGLPLLLRGVRSTRNPLGNEERIARSAAAQAAIRAIDSSHDAISADLDESGAARCADISARVMDQYR
RRLAALADDGPTPRAQAQQAETMELQMRIAAVRAERSALYRLRSDSKISDETLTKLLREIDLSETALSTRKKGIV
>Mature_555_residues
MEIVFTVLILLLTVALSGAVTRLLPLQLPLPLMQIAFGAMLAWPKLNLHVTFDPEIFMLLFIPPLLFADGWRIPKRELYL
QRRAILMLAFGLVFMTVLAVGYFAHWLIPELPLPIAFALAAVLSPTDAVALSGIAGKGRIPPQLMHILEGEALMNDASGL
VALKFAIAAALTGVFSLRAASVTFVIVAAGGLATGAIVSWVFSALSTRFLNAEQEGDPAPGIVMTLLVPFAAYLFAEHLD
LSGVLAAVSAGMMMNYTSFSRKSTVASRVRAESTWAMIEFVFNGMVFIMLGLQLPHIIGRALVDAHHTSDALVGRMIFNV
CAMMLALYAIRFLWVWLLRWFASRRAARHGLAGTMAGVRTIAVMTVGGVRGAVTLAGVLSIPVALSDGAPLPGRDTAIFI
ASAVILGSLIVGVIGLPLLLRGVRSTRNPLGNEERIARSAAAQAAIRAIDSSHDAISADLDESGAARCADISARVMDQYR
RRLAALADDGPTPRAQAQQAETMELQMRIAAVRAERSALYRLRSDSKISDETLTKLLREIDLSETALSTRKKGIV

Specific function: Unknown

COG id: COG0025

COG function: function code P; NhaP-type Na+/H+ and K+/H+ antiporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family [H]

Homologues:

Organism=Homo sapiens, GI27734935, Length=262, Percent_Identity=23.6641221374046, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI5454070, Length=286, Percent_Identity=22.3776223776224, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI110227626, Length=262, Percent_Identity=23.6641221374046, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI294997330, Length=262, Percent_Identity=23.6641221374046, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI41872703, Length=504, Percent_Identity=21.031746031746, Blast_Score=73, Evalue=8e-13,
Organism=Homo sapiens, GI14211919, Length=262, Percent_Identity=23.6641221374046, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI148727259, Length=264, Percent_Identity=25.3787878787879, Blast_Score=66, Evalue=8e-11,
Organism=Escherichia coli, GI1790501, Length=555, Percent_Identity=48.8288288288288, Blast_Score=492, Evalue=1e-140,
Organism=Caenorhabditis elegans, GI71980847, Length=380, Percent_Identity=25.2631578947368, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71999819, Length=455, Percent_Identity=23.956043956044, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71999817, Length=455, Percent_Identity=23.956043956044, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71999821, Length=403, Percent_Identity=24.0694789081886, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71987535, Length=519, Percent_Identity=21.9653179190751, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71987537, Length=519, Percent_Identity=21.9653179190751, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71990932, Length=380, Percent_Identity=24.4736842105263, Blast_Score=69, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI71993590, Length=317, Percent_Identity=24.9211356466877, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71993582, Length=317, Percent_Identity=24.9211356466877, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71990924, Length=380, Percent_Identity=24.4736842105263, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6320663, Length=261, Percent_Identity=24.1379310344828, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI221473212, Length=446, Percent_Identity=22.4215246636771, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI221473215, Length=266, Percent_Identity=25.187969924812, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI281364513, Length=266, Percent_Identity=25.187969924812, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI221473222, Length=266, Percent_Identity=25.187969924812, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI221510738, Length=401, Percent_Identity=25.1870324189526, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI221510734, Length=401, Percent_Identity=25.1870324189526, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI281360447, Length=316, Percent_Identity=24.0506329113924, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI221510732, Length=343, Percent_Identity=26.2390670553936, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI221510736, Length=343, Percent_Identity=26.2390670553936, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI221510740, Length=343, Percent_Identity=26.2390670553936, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24585580, Length=343, Percent_Identity=26.2390670553936, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24585578, Length=343, Percent_Identity=26.2390670553936, Blast_Score=68, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR018422
- InterPro:   IPR004705 [H]

Pfam domain/function: PF00999 Na_H_Exchanger [H]

EC number: NA

Molecular weight: Translated: 59613; Mature: 59613

Theoretical pI: Translated: 10.09; Mature: 10.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIVFTVLILLLTVALSGAVTRLLPLQLPLPLMQIAFGAMLAWPKLNLHVTFDPEIFMLL
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEEEEECCHHHHHH
FIPPLLFADGWRIPKRELYLQRRAILMLAFGLVFMTVLAVGYFAHWLIPELPLPIAFALA
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
AVLSPTDAVALSGIAGKGRIPPQLMHILEGEALMNDASGLVALKFAIAAALTGVFSLRAA
HHHCCCHHHHHCCCCCCCCCCHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
SVTFVIVAAGGLATGAIVSWVFSALSTRFLNAEQEGDPAPGIVMTLLVPFAAYLFAEHLD
HHEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCC
LSGVLAAVSAGMMMNYTSFSRKSTVASRVRAESTWAMIEFVFNGMVFIMLGLQLPHIIGR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALVDAHHTSDALVGRMIFNVCAMMLALYAIRFLWVWLLRWFASRRAARHGLAGTMAGVRT
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
IAVMTVGGVRGAVTLAGVLSIPVALSDGAPLPGRDTAIFIASAVILGSLIVGVIGLPLLL
HHHHEECCCHHHHHHHHHHHCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RGVRSTRNPLGNEERIARSAAAQAAIRAIDSSHDAISADLDESGAARCADISARVMDQYR
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
RRLAALADDGPTPRAQAQQAETMELQMRIAAVRAERSALYRLRSDSKISDETLTKLLREI
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHC
DLSETALSTRKKGIV
CCHHHHHHHHHCCCC
>Mature Secondary Structure
MEIVFTVLILLLTVALSGAVTRLLPLQLPLPLMQIAFGAMLAWPKLNLHVTFDPEIFMLL
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEEEEECCHHHHHH
FIPPLLFADGWRIPKRELYLQRRAILMLAFGLVFMTVLAVGYFAHWLIPELPLPIAFALA
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
AVLSPTDAVALSGIAGKGRIPPQLMHILEGEALMNDASGLVALKFAIAAALTGVFSLRAA
HHHCCCHHHHHCCCCCCCCCCHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
SVTFVIVAAGGLATGAIVSWVFSALSTRFLNAEQEGDPAPGIVMTLLVPFAAYLFAEHLD
HHEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCC
LSGVLAAVSAGMMMNYTSFSRKSTVASRVRAESTWAMIEFVFNGMVFIMLGLQLPHIIGR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALVDAHHTSDALVGRMIFNVCAMMLALYAIRFLWVWLLRWFASRRAARHGLAGTMAGVRT
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
IAVMTVGGVRGAVTLAGVLSIPVALSDGAPLPGRDTAIFIASAVILGSLIVGVIGLPLLL
HHHHEECCCHHHHHHHHHHHCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RGVRSTRNPLGNEERIARSAAAQAAIRAIDSSHDAISADLDESGAARCADISARVMDQYR
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
RRLAALADDGPTPRAQAQQAETMELQMRIAAVRAERSALYRLRSDSKISDETLTKLLREI
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHC
DLSETALSTRKKGIV
CCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503 [H]