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The map label for this gene is moeB [H]

Identifier: 116690879

GI number: 116690879

Start: 3157735

End: 3158487

Strand: Direct

Name: moeB [H]

Synonym: Bcen2424_2859

Alternate gene names: 116690879

Gene position: 3157735-3158487 (Clockwise)

Preceding gene: 116690878

Following gene: 116690887

Centisome position: 90.64

GC content: 68.92

Gene sequence:

>753_bases
ATGAACGACGATCAACTCCTTCGCTACTCCCGCCACATCCTCGTCGACGAGATCGGCATCGAGGCGCAGCAGCGCTTTCT
CGACGCGCATGCGATCGTCGTCGGCGCGGGCGGCCTCGGCTCGCCGGCCGCGATGTATCTCGCGGCGTCGGGGGTCGGCA
CGCTCACGCTCGTCGACGCCGATACGGTCGACCTCACGAACCTGCAGCGGCAGATCCTGCACGTGACGGCATCGGTCGGC
CGCAGCAAGGTCGAATCGGGGCGCGACGCGCTCGCGCAGCTGAATCCCGAGGTGACGGTGAACGCGGTCGCGGAACGCGT
CGACGACGCGTGGCTCGACGCACACGTGCCGCACGCGAGCGTCGTGCTCGACTGCACCGACAACTTCGCGACGCGGCATG
CGATCAACCGCGCGTGCGTCGCGCACGGCGTGCCGCTCGTGTCCGGCGCCGCGCTGCGCTTCGACGGCCAGATCAGCACG
TTCGACTTCCGCGACGCGGCCGCGCCCTGCTATGCGTGCGTGTTTCCGGAAGACCAGCCGTTCGAGGAAGTCGCGTGCTC
GACGATGGGCGTGTTCGCGCCCACCGTCGGGATCATCGGCGCGATGCAGGCGGCCGAGGCGCTGCGCGTGATCGGCGGCA
TCGGCAAGACACTCAACGGGCGGCTGATGATGCTCGATTCGCTGCGGATGGAATGGACGACGATGAAAATCGCGCGCCAG
GCCGACTGCCCCGTATGCGGGGGCCGGCACTGA

Upstream 100 bases:

>100_bases
CCAGCCGGCATCCAACGGGCCATCGCGGGAAGACCGCGATGGCCCGTTTTTCATGCGCGCCTAAAATAACGAACGTCCGC
CCGCCTCGCTCACGCCCCCC

Downstream 100 bases:

>100_bases
CGCGCGACGGGCATGCGCCGAACGCGCATGCGTGACACTTCGCTACAGTTAGCGGCGCCGAAAACGCCTACGCGGCCGCG
TCCGCCCGCGGCTCGGCGAC

Product: UBA/THIF-type NAD/FAD binding protein

Products: NA

Alternate protein names: MoaD protein adenylase; Molybdopterin-converting factor subunit 1 adenylase [H]

Number of amino acids: Translated: 250; Mature: 250

Protein sequence:

>250_residues
MNDDQLLRYSRHILVDEIGIEAQQRFLDAHAIVVGAGGLGSPAAMYLAASGVGTLTLVDADTVDLTNLQRQILHVTASVG
RSKVESGRDALAQLNPEVTVNAVAERVDDAWLDAHVPHASVVLDCTDNFATRHAINRACVAHGVPLVSGAALRFDGQIST
FDFRDAAAPCYACVFPEDQPFEEVACSTMGVFAPTVGIIGAMQAAEALRVIGGIGKTLNGRLMMLDSLRMEWTTMKIARQ
ADCPVCGGRH

Sequences:

>Translated_250_residues
MNDDQLLRYSRHILVDEIGIEAQQRFLDAHAIVVGAGGLGSPAAMYLAASGVGTLTLVDADTVDLTNLQRQILHVTASVG
RSKVESGRDALAQLNPEVTVNAVAERVDDAWLDAHVPHASVVLDCTDNFATRHAINRACVAHGVPLVSGAALRFDGQIST
FDFRDAAAPCYACVFPEDQPFEEVACSTMGVFAPTVGIIGAMQAAEALRVIGGIGKTLNGRLMMLDSLRMEWTTMKIARQ
ADCPVCGGRH
>Mature_250_residues
MNDDQLLRYSRHILVDEIGIEAQQRFLDAHAIVVGAGGLGSPAAMYLAASGVGTLTLVDADTVDLTNLQRQILHVTASVG
RSKVESGRDALAQLNPEVTVNAVAERVDDAWLDAHVPHASVVLDCTDNFATRHAINRACVAHGVPLVSGAALRFDGQIST
FDFRDAAAPCYACVFPEDQPFEEVACSTMGVFAPTVGIIGAMQAAEALRVIGGIGKTLNGRLMMLDSLRMEWTTMKIARQ
ADCPVCGGRH

Specific function: Catalyzes the adenylation by ATP of the carboxyl group of the C-terminal glycine of sulfur carrier protein moaD [H]

COG id: COG0476

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesA/moeB/thiF family [H]

Homologues:

Organism=Homo sapiens, GI7657339, Length=251, Percent_Identity=41.0358565737052, Blast_Score=179, Evalue=3e-45,
Organism=Homo sapiens, GI4885649, Length=167, Percent_Identity=29.940119760479, Blast_Score=86, Evalue=4e-17,
Organism=Escherichia coli, GI1787048, Length=250, Percent_Identity=44.8, Blast_Score=230, Evalue=8e-62,
Organism=Escherichia coli, GI87082356, Length=250, Percent_Identity=44.4, Blast_Score=206, Evalue=1e-54,
Organism=Escherichia coli, GI1789177, Length=132, Percent_Identity=39.3939393939394, Blast_Score=77, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17540406, Length=258, Percent_Identity=38.7596899224806, Blast_Score=193, Evalue=7e-50,
Organism=Caenorhabditis elegans, GI193203301, Length=165, Percent_Identity=27.8787878787879, Blast_Score=80, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6321903, Length=250, Percent_Identity=35.2, Blast_Score=157, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6320598, Length=165, Percent_Identity=25.4545454545455, Blast_Score=66, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6322639, Length=160, Percent_Identity=26.25, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24582879, Length=251, Percent_Identity=40.6374501992032, Blast_Score=192, Evalue=2e-49,
Organism=Drosophila melanogaster, GI24660640, Length=158, Percent_Identity=31.0126582278481, Blast_Score=85, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007901
- InterPro:   IPR009036
- InterPro:   IPR012730
- InterPro:   IPR016040
- InterPro:   IPR000594 [H]

Pfam domain/function: PF05237 MoeZ_MoeB; PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 26627; Mature: 26627

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDDQLLRYSRHILVDEIGIEAQQRFLDAHAIVVGAGGLGSPAAMYLAASGVGTLTLVDA
CCCHHHHHHHHHHHHHHHCHHHHHHHHHHEEEEEECCCCCCHHHHHEEECCCCEEEEEEC
DTVDLTNLQRQILHVTASVGRSKVESGRDALAQLNPEVTVNAVAERVDDAWLDAHVPHAS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHCCCCCCE
VVLDCTDNFATRHAINRACVAHGVPLVSGAALRFDGQISTFDFRDAAAPCYACVFPEDQP
EEEECCCCHHHHHHHHHHHHHCCCCHHCCCEEEECCCEEEECCCCCCCCEEEEECCCCCC
FEEVACSTMGVFAPTVGIIGAMQAAEALRVIGGIGKTLNGRLMMLDSLRMEWTTMKIARQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHH
ADCPVCGGRH
CCCCCCCCCC
>Mature Secondary Structure
MNDDQLLRYSRHILVDEIGIEAQQRFLDAHAIVVGAGGLGSPAAMYLAASGVGTLTLVDA
CCCHHHHHHHHHHHHHHHCHHHHHHHHHHEEEEEECCCCCCHHHHHEEECCCCEEEEEEC
DTVDLTNLQRQILHVTASVGRSKVESGRDALAQLNPEVTVNAVAERVDDAWLDAHVPHAS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHCCCCCCE
VVLDCTDNFATRHAINRACVAHGVPLVSGAALRFDGQISTFDFRDAAAPCYACVFPEDQP
EEEECCCCHHHHHHHHHHHHHCCCCHHCCCEEEECCCEEEECCCCCCCCEEEEECCCCCC
FEEVACSTMGVFAPTVGIIGAMQAAEALRVIGGIGKTLNGRLMMLDSLRMEWTTMKIARQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHH
ADCPVCGGRH
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3045084; 8905232; 9278503 [H]