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The map label for this gene is gpmA [H]

Identifier: 116690877

GI number: 116690877

Start: 3155015

End: 3155827

Strand: Direct

Name: gpmA [H]

Synonym: Bcen2424_2857

Alternate gene names: 116690877

Gene position: 3155015-3155827 (Clockwise)

Preceding gene: 116690871

Following gene: 116690878

Centisome position: 90.56

GC content: 67.28

Gene sequence:

>813_bases
ATGTCGGGCCCCGGTTCGGTCCCGTGCGGCGCGCCCCGCTTCCCATCACTACCGACCGCAAGATCCATGTACAAACTCGT
TCTCATCCGCCACGGCGAATCGACGTGGAACAAGGAAAACCGCTTCACCGGCTGGGTCGACGTCGACCTGACCGAACAGG
GTCGCAACGAGGCCTACCAGGCCGGCGAACTGCTCAAGGAGGCCGGCTACACGTTCGACATCGCGTACACGTCGGTGCTC
AAGCGCGCGATCCGCACGCTGTGGCACGTGCAGGACAAGATGGACCTGATGTACCTGCCGGTCGTCCACTCGTGGCGCCT
GAACGAGCGCCACTACGGCGCGCTGTCGGGCCTGAACAAGGCGGAAACGGCCGCGAAGTTCGGCGACGAGCAGGTGCTCG
TGTGGCGCCGCAGCTACGACACACCGCCGCCCGCGCTCGAGCCGACCGACGAGCGCGCGCCGTTCAACGACCCGCGCTAC
GCGAAGGTGCCGCGCGAGCAACTGCCGCTCACCGAGTGCCTGAAGGACACGGTCGCGCGCGTGCTGCCGCTGTGGAACGA
GTCGATCGCGCCGGCGGTGCGCGCCGGCAAGCAGGTGCTGATCGCCGCGCACGGCAACTCGCTGCGCGCGCTGATCAAGT
ACCTCGACGGCATCTCGGACAGCGACATCGTCGGCCTGAACATCCCGAACGGCGTGCCGCTCGTGTATGAGCTCGACGAG
AACCTGAAGCCGATCAAGCACTATTACCTCGGCGACCAGGACGCGATCGCGCAGGCGCAGGCCGCCGTCGCGAAGCAGGG
CAAGGCGGGCTGA

Upstream 100 bases:

>100_bases
CCAGGTTCGTGTAATTGGTAAAGAACGTCACGGAATGCCGCCGGAAAAAGAGAAATCGGATGAGGACAATCCCGCCATTA
TAAAATAACCGTCTTGCGCG

Downstream 100 bases:

>100_bases
TGCCCGGCGCGGCGAGCAGGCCGCGTTCCGGCGCGGCGTGCCGGGCCCCGGCCCGCACGCCGCGCGAACCTTCCCGGCCC
CGCTGCGGTCGAACCCGCTT

Product: phosphoglyceromutase

Products: NA

Alternate protein names: BPG-dependent PGAM; PGAM; Phosphoglyceromutase; dPGM [H]

Number of amino acids: Translated: 270; Mature: 269

Protein sequence:

>270_residues
MSGPGSVPCGAPRFPSLPTARSMYKLVLIRHGESTWNKENRFTGWVDVDLTEQGRNEAYQAGELLKEAGYTFDIAYTSVL
KRAIRTLWHVQDKMDLMYLPVVHSWRLNERHYGALSGLNKAETAAKFGDEQVLVWRRSYDTPPPALEPTDERAPFNDPRY
AKVPREQLPLTECLKDTVARVLPLWNESIAPAVRAGKQVLIAAHGNSLRALIKYLDGISDSDIVGLNIPNGVPLVYELDE
NLKPIKHYYLGDQDAIAQAQAAVAKQGKAG

Sequences:

>Translated_270_residues
MSGPGSVPCGAPRFPSLPTARSMYKLVLIRHGESTWNKENRFTGWVDVDLTEQGRNEAYQAGELLKEAGYTFDIAYTSVL
KRAIRTLWHVQDKMDLMYLPVVHSWRLNERHYGALSGLNKAETAAKFGDEQVLVWRRSYDTPPPALEPTDERAPFNDPRY
AKVPREQLPLTECLKDTVARVLPLWNESIAPAVRAGKQVLIAAHGNSLRALIKYLDGISDSDIVGLNIPNGVPLVYELDE
NLKPIKHYYLGDQDAIAQAQAAVAKQGKAG
>Mature_269_residues
SGPGSVPCGAPRFPSLPTARSMYKLVLIRHGESTWNKENRFTGWVDVDLTEQGRNEAYQAGELLKEAGYTFDIAYTSVLK
RAIRTLWHVQDKMDLMYLPVVHSWRLNERHYGALSGLNKAETAAKFGDEQVLVWRRSYDTPPPALEPTDERAPFNDPRYA
KVPREQLPLTECLKDTVARVLPLWNESIAPAVRAGKQVLIAAHGNSLRALIKYLDGISDSDIVGLNIPNGVPLVYELDEN
LKPIKHYYLGDQDAIAQAQAAVAKQGKAG

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate [H]

COG id: COG0588

COG function: function code G; Phosphoglycerate mutase 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily [H]

Homologues:

Organism=Homo sapiens, GI50593010, Length=254, Percent_Identity=57.4803149606299, Blast_Score=310, Evalue=8e-85,
Organism=Homo sapiens, GI4505753, Length=249, Percent_Identity=61.0441767068273, Blast_Score=303, Evalue=1e-82,
Organism=Homo sapiens, GI71274132, Length=251, Percent_Identity=58.9641434262948, Blast_Score=289, Evalue=2e-78,
Organism=Homo sapiens, GI4502445, Length=256, Percent_Identity=51.5625, Blast_Score=267, Evalue=7e-72,
Organism=Homo sapiens, GI40353764, Length=256, Percent_Identity=51.5625, Blast_Score=267, Evalue=7e-72,
Organism=Homo sapiens, GI310129614, Length=162, Percent_Identity=62.962962962963, Blast_Score=197, Evalue=1e-50,
Organism=Escherichia coli, GI1786970, Length=248, Percent_Identity=65.7258064516129, Blast_Score=335, Evalue=3e-93,
Organism=Saccharomyces cerevisiae, GI6322697, Length=249, Percent_Identity=55.421686746988, Blast_Score=252, Evalue=5e-68,
Organism=Saccharomyces cerevisiae, GI6324516, Length=293, Percent_Identity=32.7645051194539, Blast_Score=154, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6320183, Length=298, Percent_Identity=32.2147651006711, Blast_Score=144, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24646216, Length=253, Percent_Identity=52.1739130434783, Blast_Score=275, Evalue=3e-74,
Organism=Drosophila melanogaster, GI85725270, Length=250, Percent_Identity=52.8, Blast_Score=263, Evalue=8e-71,
Organism=Drosophila melanogaster, GI85725272, Length=250, Percent_Identity=52.8, Blast_Score=263, Evalue=8e-71,
Organism=Drosophila melanogaster, GI24650981, Length=250, Percent_Identity=52.8, Blast_Score=263, Evalue=8e-71,
Organism=Drosophila melanogaster, GI28571815, Length=251, Percent_Identity=41.4342629482072, Blast_Score=184, Evalue=6e-47,
Organism=Drosophila melanogaster, GI28571817, Length=251, Percent_Identity=41.4342629482072, Blast_Score=184, Evalue=7e-47,
Organism=Drosophila melanogaster, GI24648979, Length=251, Percent_Identity=41.4342629482072, Blast_Score=183, Evalue=9e-47,

Paralogues:

None

Copy number: 960 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR005952 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =5.4.2.1 [H]

Molecular weight: Translated: 30080; Mature: 29948

Theoretical pI: Translated: 7.65; Mature: 7.65

Prosite motif: PS00175 PG_MUTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGPGSVPCGAPRFPSLPTARSMYKLVLIRHGESTWNKENRFTGWVDVDLTEQGRNEAYQ
CCCCCCCCCCCCCCCCCCCHHHHHEEHEEECCCCCCCCCCCEEEEEEEEECCCCCHHHHH
AGELLKEAGYTFDIAYTSVLKRAIRTLWHVQDKMDLMYLPVVHSWRLNERHYGALSGLNK
HHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHCCCEEEECCHHCEECCCCHHHHHHCCCH
AETAAKFGDEQVLVWRRSYDTPPPALEPTDERAPFNDPRYAKVPREQLPLTECLKDTVAR
HHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCHHHHHHHHHHH
VLPLWNESIAPAVRAGKQVLIAAHGNSLRALIKYLDGISDSDIVGLNIPNGVPLVYELDE
HHHHCCCHHHHHHHCCCEEEEEECCCHHHHHHHHHCCCCCCCEEEEECCCCCCEEEECCC
NLKPIKHYYLGDQDAIAQAQAAVAKQGKAG
CCCHHHHHHCCCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SGPGSVPCGAPRFPSLPTARSMYKLVLIRHGESTWNKENRFTGWVDVDLTEQGRNEAYQ
CCCCCCCCCCCCCCCCCCHHHHHEEHEEECCCCCCCCCCCEEEEEEEEECCCCCHHHHH
AGELLKEAGYTFDIAYTSVLKRAIRTLWHVQDKMDLMYLPVVHSWRLNERHYGALSGLNK
HHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHCCCEEEECCHHCEECCCCHHHHHHCCCH
AETAAKFGDEQVLVWRRSYDTPPPALEPTDERAPFNDPRYAKVPREQLPLTECLKDTVAR
HHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCHHHHHHHHHHH
VLPLWNESIAPAVRAGKQVLIAAHGNSLRALIKYLDGISDSDIVGLNIPNGVPLVYELDE
HHHHCCCHHHHHHHCCCEEEEEECCCHHHHHHHHHCCCCCCCEEEEECCCCCCEEEECCC
NLKPIKHYYLGDQDAIAQAQAAVAKQGKAG
CCCHHHHHHCCCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA