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The map label for this gene is glmS [H]

Identifier: 116690843

GI number: 116690843

Start: 3123210

End: 3124241

Strand: Reverse

Name: glmS [H]

Synonym: Bcen2424_2823

Alternate gene names: 116690843

Gene position: 3124241-3123210 (Counterclockwise)

Preceding gene: 116690844

Following gene: 116690842

Centisome position: 89.68

GC content: 72.0

Gene sequence:

>1032_bases
ATGCTTAAGGAAGCGCGCGAGTCCGCCCAGGTCGTCGCCGCGCAGATCGCCGACACCACGCGCGTCGAAGCGCTCGCCGG
CCAATTGCTCGATCACCCGCCGGCCGTCGCGCTGACGGTCGCGCGCGGCAGCTCGGATCACGCCGCCAGCTATTTCGCGA
GCCTGACGATGAGCCGCCTCGGCGTGCCCGTCGCGTCGCTGCCGATGTCGGTCGCGACGCTGCAGCAGGCGCCGCTGAAG
GTGCAGGACCAGCTCGCGCTCGCGTTCTCCCAGTCGGGCAAGAGCCCCGATCTCGTCAACACGATGGCCGCGCTGCGCGA
AGCCGGCGCGCGTACCGTCGCCGCCGTGAACGTGCTGCCGTCGCCGCTCGCCGATGCGTGCGAGCACCAGTTGCCGCTGC
TGGCCGGCCCCGAACTGTCGGTCGCCGCGACCAAGAGCTATATCGCGATGCTGTCGGCTTCCGCGCAGATCGTCGCGTAC
TGGCAGCGCGACGCCGCGCTGATCACCGCATTGCGCGGCCTGCCCGACGTGCTCGCGCAGGCCGGCCGGCTCGACTGGTC
GCCGGCCGTCGCGGCGCTCGCGGGCGTCGAACGGATGATCGTGATCGGCCGCGGGCTGGGCCTCGCGATCGCGCAGGAAG
CCGCGCTGAAGCTGAAGGAAACGTCCGGCATCCAGGCCGAGGCGTTCTCGAGCGCCGAAGTCCGCCACGGCCCGATGGAA
CTGATCGACCGCGACTATCCGCTGCTCGTGTTCGCGCCGCCGGGGCCCGAGCAGGCCGGCCTGCTGCAGCTCGCCGCCGA
CATGCGCGCACGCGGCGCCGCCGTGCTGCTCGCGGCGCCCGCCGGCACGCCCGGCGTATCGACGCCCGGCGTATCGGGCA
CCGTGCTGCCGCTCGCGCAGTCCGCCCATTCGGCGCTCGACCCGATCGCCGCCATTCTTTCGTTCTACGTGATGGCGGCG
GATCTCGCCGTCGCACGCGGCCGCAATCCCGACACGCCGCGCCACCTGAACAAAGTCACCGAAACGCACTGA

Upstream 100 bases:

>100_bases
CGCGGCCGCCTCGAGCGCGGCGCCTGGGCCGACCTCGCGGTGTTCGATCGCGACCTGAACCTCACCGCGACCTATGTCGA
AGGAGAATCGATTGTCGAAT

Downstream 100 bases:

>100_bases
TAGCCGAGAAAGCCGATGAGACGCGCCGAGGAATCCCAGTTGAAGAGCCCCAACCACGATCAGATCGTTCTGCTTAGCCC
GTTGACGGGGCCGATCGTCG

Product: glutamine--fructose-6-phosphate transaminase (isomerizing)

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MLKEARESAQVVAAQIADTTRVEALAGQLLDHPPAVALTVARGSSDHAASYFASLTMSRLGVPVASLPMSVATLQQAPLK
VQDQLALAFSQSGKSPDLVNTMAALREAGARTVAAVNVLPSPLADACEHQLPLLAGPELSVAATKSYIAMLSASAQIVAY
WQRDAALITALRGLPDVLAQAGRLDWSPAVAALAGVERMIVIGRGLGLAIAQEAALKLKETSGIQAEAFSSAEVRHGPME
LIDRDYPLLVFAPPGPEQAGLLQLAADMRARGAAVLLAAPAGTPGVSTPGVSGTVLPLAQSAHSALDPIAAILSFYVMAA
DLAVARGRNPDTPRHLNKVTETH

Sequences:

>Translated_343_residues
MLKEARESAQVVAAQIADTTRVEALAGQLLDHPPAVALTVARGSSDHAASYFASLTMSRLGVPVASLPMSVATLQQAPLK
VQDQLALAFSQSGKSPDLVNTMAALREAGARTVAAVNVLPSPLADACEHQLPLLAGPELSVAATKSYIAMLSASAQIVAY
WQRDAALITALRGLPDVLAQAGRLDWSPAVAALAGVERMIVIGRGLGLAIAQEAALKLKETSGIQAEAFSSAEVRHGPME
LIDRDYPLLVFAPPGPEQAGLLQLAADMRARGAAVLLAAPAGTPGVSTPGVSGTVLPLAQSAHSALDPIAAILSFYVMAA
DLAVARGRNPDTPRHLNKVTETH
>Mature_343_residues
MLKEARESAQVVAAQIADTTRVEALAGQLLDHPPAVALTVARGSSDHAASYFASLTMSRLGVPVASLPMSVATLQQAPLK
VQDQLALAFSQSGKSPDLVNTMAALREAGARTVAAVNVLPSPLADACEHQLPLLAGPELSVAATKSYIAMLSASAQIVAY
WQRDAALITALRGLPDVLAQAGRLDWSPAVAALAGVERMIVIGRGLGLAIAQEAALKLKETSGIQAEAFSSAEVRHGPME
LIDRDYPLLVFAPPGPEQAGLLQLAADMRARGAAVLLAAPAGTPGVSTPGVSGTVLPLAQSAHSALDPIAAILSFYVMAA
DLAVARGRNPDTPRHLNKVTETH

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG2222

COG function: function code M; Predicted phosphosugar isomerases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Homo sapiens, GI4826742, Length=357, Percent_Identity=25.7703081232493, Blast_Score=101, Evalue=8e-22,
Organism=Homo sapiens, GI205277386, Length=328, Percent_Identity=24.390243902439, Blast_Score=96, Evalue=6e-20,
Organism=Escherichia coli, GI1790167, Length=325, Percent_Identity=29.5384615384615, Blast_Score=100, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17539970, Length=333, Percent_Identity=25.2252252252252, Blast_Score=95, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17532897, Length=311, Percent_Identity=24.7588424437299, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17532899, Length=311, Percent_Identity=24.7588424437299, Blast_Score=94, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6322745, Length=311, Percent_Identity=25.4019292604502, Blast_Score=92, Evalue=1e-19,
Organism=Drosophila melanogaster, GI21357745, Length=356, Percent_Identity=23.876404494382, Blast_Score=96, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 35390; Mature: 35390

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKEARESAQVVAAQIADTTRVEALAGQLLDHPPAVALTVARGSSDHAASYFASLTMSRL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHH
GVPVASLPMSVATLQQAPLKVQDQLALAFSQSGKSPDLVNTMAALREAGARTVAAVNVLP
CCCHHHHCHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHEEEECCCC
SPLADACEHQLPLLAGPELSVAATKSYIAMLSASAQIVAYWQRDAALITALRGLPDVLAQ
CHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHCCHHHHHH
AGRLDWSPAVAALAGVERMIVIGRGLGLAIAQEAALKLKETSGIQAEAFSSAEVRHGPME
HCCCCCHHHHHHHHHHHEEEEEECCCCHHHHHHHHHHHHHCCCCCHHHCCCCHHCCCCHH
LIDRDYPLLVFAPPGPEQAGLLQLAADMRARGAAVLLAAPAGTPGVSTPGVSGTVLPLAQ
HHCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCHHHHHH
SAHSALDPIAAILSFYVMAADLAVARGRNPDTPRHLNKVTETH
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCC
>Mature Secondary Structure
MLKEARESAQVVAAQIADTTRVEALAGQLLDHPPAVALTVARGSSDHAASYFASLTMSRL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHH
GVPVASLPMSVATLQQAPLKVQDQLALAFSQSGKSPDLVNTMAALREAGARTVAAVNVLP
CCCHHHHCHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHEEEECCCC
SPLADACEHQLPLLAGPELSVAATKSYIAMLSASAQIVAYWQRDAALITALRGLPDVLAQ
CHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHCCHHHHHH
AGRLDWSPAVAALAGVERMIVIGRGLGLAIAQEAALKLKETSGIQAEAFSSAEVRHGPME
HCCCCCHHHHHHHHHHHEEEEEECCCCHHHHHHHHHHHHHCCCCCHHHCCCCHHCCCCHH
LIDRDYPLLVFAPPGPEQAGLLQLAADMRARGAAVLLAAPAGTPGVSTPGVSGTVLPLAQ
HHCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCHHHHHH
SAHSALDPIAAILSFYVMAADLAVARGRNPDTPRHLNKVTETH
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA