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The map label for this gene is hprK

Identifier: 116690814

GI number: 116690814

Start: 3090447

End: 3091415

Strand: Direct

Name: hprK

Synonym: Bcen2424_2794

Alternate gene names: 116690814

Gene position: 3090447-3091415 (Clockwise)

Preceding gene: 116690813

Following gene: 116690815

Centisome position: 88.71

GC content: 66.25

Gene sequence:

>969_bases
ATGGATACGTCCAGCATCAACGCCCAGAGCATCTTCGACGACAACGCAGCCACGCTGAAACTGAGCTGGCTGACGGGGCA
TGAAGGCTGGGAACGCGGCTTTTCGGCCGACACGGTCGGCAACGCAACGTCGAGCGCCGACCTCGTCGGCCACCTGAACC
TGATCCACCCGAACCGGATCCAGGTGCTCGGCGAAGCCGAAATCGACTACTACCAGCGCCAGACCGACGAAGACCGTTCG
CGCCACATGGCCGAGCTGATCGCGCTCGAACCACCGTTCCTCGTCGTCGCCGGCGGTGCCGCGGCGCCGCCCGAACTGGT
GCTGCGCTGCACGCGCTCGTCCACCCCGCTGTTCACGACGCCGATGTCGGCCGCCGCCGTGATCGACAGCCTGCGGCTCT
ACATGTCGCGCATCCTCGCGCCGCGCGCGACGCTGCACGGCGTGTTCCTCGACATTCTCGGGATGGGCGTGCTGCTGACC
GGCGATTCGGGCCTCGGCAAGAGCGAACTCGGCCTCGAGCTGATCAGCCGCGGGCACGGCCTCGTCGCCGACGACGCGGT
CGATTTCGTCCGTCTTGGCCCCGATTTCGTCGAAGGGCGCTGCCCGCCGCTGCTGCAGAACCTGCTCGAAGTGCGCGGCC
TCGGCCTGCTCGACATCAAGACGATCTTCGGCGAAACCGCCGTGCGGCGGAAAATGAAGCTGAAGCTGATCGTTCAGCTC
GTGCGGCGCCCCGACGGCGAATTCCAGCGCCTGCCGCTCGAAAGCCAGACCGTCGACGTGCTCGGGTTGCCGATCAGCAA
GGTCACGATCCAGGTCGCGGCCGGCCGCAACCTCGCGGTGCTCGTCGAGGCGGCCGTCCGGAACACGATCCTGCAGTTGC
GCGGAATCGACACGTTGCGCGATTTCATGGATCGGCAACGACTCGCGATGCAAGATCCCGACAGTCAGTTCCCCGGCAAA
CTGGTGTAA

Upstream 100 bases:

>100_bases
GAGGCGGCCCACGCCGCCGTCCAGGGCCGCCCGGCGCCGGCCCGGCATGGCGACGTCCGTCGCCGCGCGCCCGCACCGGC
CCATTGGAGTGACGAGAGTC

Downstream 100 bases:

>100_bases
CCCGCACGCGCCGGCCGCGCAACGCCGACGCGTCGAGCCGGTGCTATGATGAAACGTCAGGATTCTCTGTTCCCATGCGC
ATCGTCCTCATCACCGGCAT

Product: HPr kinase/phosphorylase

Products: NA

Alternate protein names: HPrK/P; HPr(Ser) kinase/phosphorylase

Number of amino acids: Translated: 322; Mature: 322

Protein sequence:

>322_residues
MDTSSINAQSIFDDNAATLKLSWLTGHEGWERGFSADTVGNATSSADLVGHLNLIHPNRIQVLGEAEIDYYQRQTDEDRS
RHMAELIALEPPFLVVAGGAAAPPELVLRCTRSSTPLFTTPMSAAAVIDSLRLYMSRILAPRATLHGVFLDILGMGVLLT
GDSGLGKSELGLELISRGHGLVADDAVDFVRLGPDFVEGRCPPLLQNLLEVRGLGLLDIKTIFGETAVRRKMKLKLIVQL
VRRPDGEFQRLPLESQTVDVLGLPISKVTIQVAAGRNLAVLVEAAVRNTILQLRGIDTLRDFMDRQRLAMQDPDSQFPGK
LV

Sequences:

>Translated_322_residues
MDTSSINAQSIFDDNAATLKLSWLTGHEGWERGFSADTVGNATSSADLVGHLNLIHPNRIQVLGEAEIDYYQRQTDEDRS
RHMAELIALEPPFLVVAGGAAAPPELVLRCTRSSTPLFTTPMSAAAVIDSLRLYMSRILAPRATLHGVFLDILGMGVLLT
GDSGLGKSELGLELISRGHGLVADDAVDFVRLGPDFVEGRCPPLLQNLLEVRGLGLLDIKTIFGETAVRRKMKLKLIVQL
VRRPDGEFQRLPLESQTVDVLGLPISKVTIQVAAGRNLAVLVEAAVRNTILQLRGIDTLRDFMDRQRLAMQDPDSQFPGK
LV
>Mature_322_residues
MDTSSINAQSIFDDNAATLKLSWLTGHEGWERGFSADTVGNATSSADLVGHLNLIHPNRIQVLGEAEIDYYQRQTDEDRS
RHMAELIALEPPFLVVAGGAAAPPELVLRCTRSSTPLFTTPMSAAAVIDSLRLYMSRILAPRATLHGVFLDILGMGVLLT
GDSGLGKSELGLELISRGHGLVADDAVDFVRLGPDFVEGRCPPLLQNLLEVRGLGLLDIKTIFGETAVRRKMKLKLIVQL
VRRPDGEFQRLPLESQTVDVLGLPISKVTIQVAAGRNLAVLVEAAVRNTILQLRGIDTLRDFMDRQRLAMQDPDSQFPGK
LV

Specific function: Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-pr

COG id: COG1493

COG function: function code T; Serine kinase of the HPr protein, regulates carbohydrate metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HPrK/P family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HPRK_BURCA (Q1BTH4)

Other databases:

- EMBL:   CP000378
- RefSeq:   YP_622054.1
- ProteinModelPortal:   Q1BTH4
- SMR:   Q1BTH4
- STRING:   Q1BTH4
- GeneID:   4092112
- GenomeReviews:   CP000378_GR
- KEGG:   bcn:Bcen_2180
- eggNOG:   COG1493
- HOGENOM:   HBG566466
- OMA:   IHGVLVD
- ProtClustDB:   PRK05428
- BioCyc:   BCEN331271:BCEN_2180-MONOMER
- HAMAP:   MF_01249
- InterPro:   IPR003755
- InterPro:   IPR011104
- InterPro:   IPR011126

Pfam domain/function: PF07475 Hpr_kinase_C; PF02603 Hpr_kinase_N

EC number: NA

Molecular weight: Translated: 35121; Mature: 35121

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: NA

Important sites: ACT_SITE 146-146 ACT_SITE 167-167 ACT_SITE 185-185 ACT_SITE 250-250

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTSSINAQSIFDDNAATLKLSWLTGHEGWERGFSADTVGNATSSADLVGHLNLIHPNRI
CCCCCCCHHHEECCCCEEEEEEEEECCCHHHCCCCCCCCCCCCCCCHHHEEEEEECCCEE
QVLGEAEIDYYQRQTDEDRSRHMAELIALEPPFLVVAGGAAAPPELVLRCTRSSTPLFTT
EEEECCHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHEEECCCCCCEEEC
PMSAAAVIDSLRLYMSRILAPRATLHGVFLDILGMGVLLTGDSGLGKSELGLELISRGHG
CHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHCCCC
LVADDAVDFVRLGPDFVEGRCPPLLQNLLEVRGLGLLDIKTIFGETAVRRKMKLKLIVQL
CEEHHHHHHHHCCCHHHCCCCCHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHH
VRRPDGEFQRLPLESQTVDVLGLPISKVTIQVAAGRNLAVLVEAAVRNTILQLRGIDTLR
HHCCCCCHHCCCCCCCCEEEECCCHHHEEEEEECCCCEEEEHHHHHHHHHHHHCCCHHHH
DFMDRQRLAMQDPDSQFPGKLV
HHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MDTSSINAQSIFDDNAATLKLSWLTGHEGWERGFSADTVGNATSSADLVGHLNLIHPNRI
CCCCCCCHHHEECCCCEEEEEEEEECCCHHHCCCCCCCCCCCCCCCHHHEEEEEECCCEE
QVLGEAEIDYYQRQTDEDRSRHMAELIALEPPFLVVAGGAAAPPELVLRCTRSSTPLFTT
EEEECCHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHEEECCCCCCEEEC
PMSAAAVIDSLRLYMSRILAPRATLHGVFLDILGMGVLLTGDSGLGKSELGLELISRGHG
CHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHCCCC
LVADDAVDFVRLGPDFVEGRCPPLLQNLLEVRGLGLLDIKTIFGETAVRRKMKLKLIVQL
CEEHHHHHHHHCCCHHHCCCCCHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHH
VRRPDGEFQRLPLESQTVDVLGLPISKVTIQVAAGRNLAVLVEAAVRNTILQLRGIDTLR
HHCCCCCHHCCCCCCCCEEEECCCHHHEEEEEECCCCEEEEHHHHHHHHHHHHCCCHHHH
DFMDRQRLAMQDPDSQFPGKLV
HHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA