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The map label for this gene is sucC [H]

Identifier: 116690669

GI number: 116690669

Start: 2935171

End: 2936337

Strand: Reverse

Name: sucC [H]

Synonym: Bcen2424_2649

Alternate gene names: 116690669

Gene position: 2936337-2935171 (Counterclockwise)

Preceding gene: 116690670

Following gene: 116690668

Centisome position: 84.28

GC content: 62.9

Gene sequence:

>1167_bases
ATGAAGATTCACGAGTACCAGGGTAAGGAAATCCTGCGGAAATTCGGAGTCGCGGTACCGCGCGGCAAGCCGGCGTTCTC
GGTTGACGAGGCCGTCAAGGTGGCGGAAGAGCTCGGCGGCCCGGTATGGGTCGTGAAGGCTCAGATTCACGCGGGTGGCC
GTGGCAAGGGCGGCGGCGTGAAGGTGGCGAAGTCGATCGAGCAGGTCCGCGAATACGCGAACCAGATCCTCGGCATGCAG
CTCGTCACGCACCAGACCGGTCCGGAAGGCCAGAAGGTCAACCGTCTGATGATCGAGGAAGGCGCCGACATCAAGCAGGA
ACTGTATGTCAGCCTCGTCGTCGACCGCATCTCGCAGAAGATCGTGCTGATGGGCTCGAGCGAAGGCGGCATGGACATCG
AAGAAGTCGCCGAGAAGCACCCGGAACTGATCCACAAGGTCATCGTCGAGCCGTCGACGGGCCTGCTGGACGCGCAGGCC
GACGACCTCGCCGCGAAGATCGGCGTGCCGGCTGCGTCGATTCCGCAAGCGCGCGCGATCCTGCAAGGCCTGTACAAGGC
ATTCTGGGAAACCGACGCATCGCTGGCCGAAATCAACCCGCTGAACGTCTCCGGCGACGGCAAGGTCACCGCACTCGACG
CGAAGTTCAACTTCGACTCGAACGCGCTGTTCCGTCACCCGGAAATCGTCGCGTACCGCGATCTGGACGAAGAAGATCCG
GCTGAAATCGAAGCGTCGAAGTTCGACCTCGCGTACATCTCGCTCGACGGCAACATCGGCTGTCTCGTGAACGGCGCGGG
CCTCGCGATGGCGACGATGGACACGATCAAGCTGTTCGGCGGCGAACCGGCGAACTTCCTGGACGTCGGCGGAGGCGCGA
CGACCGAGAAGGTCACGGAAGCGTTCAAGCTGATGCTGAAGAACCCGGACCTGAAGGCGATCCTCGTGAACATCTTCGGC
GGCATCATGCGCTGCGACGTGATCGCGGAAGGCGTGATCGCCGGTTCGAAGGCCGTGAACCTGAACGTGCCGCTGGTCGT
GCGCATGAAGGGCACGAACGAGGACCTCGGCAAGAAGATGCTGGCCGATTCGGGCCTGCCGATCATCTCGGCGGACAGCA
TGGAAGAGGCTGCGCAGAAGGTCGTCGCGGCTGCCGCAGGCAAGTAA

Upstream 100 bases:

>100_bases
ATCTGCCCGGTGAAGGCAGCACGAAGGAATGAACGGAAATCATTCGAAGAAGCGTCTTAAGCGACTTTTCATCCAACTCT
CAGACTGAAGGGAATCACGC

Downstream 100 bases:

>100_bases
GCACGCGCTAATGAACACGTAGGGCGGCGCGGTTTGCACGCGACGCCCATCGAACAGAGGTCAAAATACATGTCGATTCT
GATCAACAAGGACACGAAGG

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta [H]

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MKIHEYQGKEILRKFGVAVPRGKPAFSVDEAVKVAEELGGPVWVVKAQIHAGGRGKGGGVKVAKSIEQVREYANQILGMQ
LVTHQTGPEGQKVNRLMIEEGADIKQELYVSLVVDRISQKIVLMGSSEGGMDIEEVAEKHPELIHKVIVEPSTGLLDAQA
DDLAAKIGVPAASIPQARAILQGLYKAFWETDASLAEINPLNVSGDGKVTALDAKFNFDSNALFRHPEIVAYRDLDEEDP
AEIEASKFDLAYISLDGNIGCLVNGAGLAMATMDTIKLFGGEPANFLDVGGGATTEKVTEAFKLMLKNPDLKAILVNIFG
GIMRCDVIAEGVIAGSKAVNLNVPLVVRMKGTNEDLGKKMLADSGLPIISADSMEEAAQKVVAAAAGK

Sequences:

>Translated_388_residues
MKIHEYQGKEILRKFGVAVPRGKPAFSVDEAVKVAEELGGPVWVVKAQIHAGGRGKGGGVKVAKSIEQVREYANQILGMQ
LVTHQTGPEGQKVNRLMIEEGADIKQELYVSLVVDRISQKIVLMGSSEGGMDIEEVAEKHPELIHKVIVEPSTGLLDAQA
DDLAAKIGVPAASIPQARAILQGLYKAFWETDASLAEINPLNVSGDGKVTALDAKFNFDSNALFRHPEIVAYRDLDEEDP
AEIEASKFDLAYISLDGNIGCLVNGAGLAMATMDTIKLFGGEPANFLDVGGGATTEKVTEAFKLMLKNPDLKAILVNIFG
GIMRCDVIAEGVIAGSKAVNLNVPLVVRMKGTNEDLGKKMLADSGLPIISADSMEEAAQKVVAAAAGK
>Mature_388_residues
MKIHEYQGKEILRKFGVAVPRGKPAFSVDEAVKVAEELGGPVWVVKAQIHAGGRGKGGGVKVAKSIEQVREYANQILGMQ
LVTHQTGPEGQKVNRLMIEEGADIKQELYVSLVVDRISQKIVLMGSSEGGMDIEEVAEKHPELIHKVIVEPSTGLLDAQA
DDLAAKIGVPAASIPQARAILQGLYKAFWETDASLAEINPLNVSGDGKVTALDAKFNFDSNALFRHPEIVAYRDLDEEDP
AEIEASKFDLAYISLDGNIGCLVNGAGLAMATMDTIKLFGGEPANFLDVGGGATTEKVTEAFKLMLKNPDLKAILVNIFG
GIMRCDVIAEGVIAGSKAVNLNVPLVVRMKGTNEDLGKKMLADSGLPIISADSMEEAAQKVVAAAAGK

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI11321583, Length=389, Percent_Identity=47.8149100257069, Blast_Score=353, Evalue=1e-97,
Organism=Homo sapiens, GI157779135, Length=383, Percent_Identity=46.4751958224543, Blast_Score=330, Evalue=1e-90,
Organism=Homo sapiens, GI294862256, Length=359, Percent_Identity=46.5181058495822, Blast_Score=312, Evalue=4e-85,
Organism=Escherichia coli, GI1786948, Length=388, Percent_Identity=52.5773195876289, Blast_Score=400, Evalue=1e-113,
Organism=Caenorhabditis elegans, GI17539378, Length=393, Percent_Identity=45.5470737913486, Blast_Score=339, Evalue=1e-93,
Organism=Caenorhabditis elegans, GI17567829, Length=390, Percent_Identity=44.1025641025641, Blast_Score=327, Evalue=5e-90,
Organism=Saccharomyces cerevisiae, GI6321683, Length=392, Percent_Identity=45.4081632653061, Blast_Score=349, Evalue=4e-97,
Organism=Drosophila melanogaster, GI21356231, Length=392, Percent_Identity=44.3877551020408, Blast_Score=326, Evalue=1e-89,
Organism=Drosophila melanogaster, GI161078106, Length=392, Percent_Identity=44.3877551020408, Blast_Score=318, Evalue=3e-87,
Organism=Drosophila melanogaster, GI24645208, Length=392, Percent_Identity=44.3877551020408, Blast_Score=318, Evalue=3e-87,
Organism=Drosophila melanogaster, GI281361397, Length=393, Percent_Identity=44.529262086514, Blast_Score=317, Evalue=7e-87,
Organism=Drosophila melanogaster, GI281361395, Length=393, Percent_Identity=44.529262086514, Blast_Score=317, Evalue=7e-87,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102 [H]

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 41254; Mature: 41254

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS50975 ATP_GRASP ; PS00063 ALDOKETO_REDUCTASE_3 ; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIHEYQGKEILRKFGVAVPRGKPAFSVDEAVKVAEELGGPVWVVKAQIHAGGRGKGGGV
CCCCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCH
KVAKSIEQVREYANQILGMQLVTHQTGPEGQKVNRLMIEEGADIKQELYVSLVVDRISQK
HHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCE
IVLMGSSEGGMDIEEVAEKHPELIHKVIVEPSTGLLDAQADDLAAKIGVPAASIPQARAI
EEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHH
LQGLYKAFWETDASLAEINPLNVSGDGKVTALDAKFNFDSNALFRHPEIVAYRDLDEEDP
HHHHHHHHHCCCCCHHCCCCEEECCCCCEEEEEEEECCCCCCEECCCCEEEECCCCCCCC
AEIEASKFDLAYISLDGNIGCLVNGAGLAMATMDTIKLFGGEPANFLDVGGGATTEKVTE
CCCCCCEEEEEEEEECCCEEEEEECCCEEEHHHHHHHHCCCCCCCEEECCCCCCHHHHHH
AFKLMLKNPDLKAILVNIFGGIMRCDVIAEGVIAGSKAVNLNVPLVVRMKGTNEDLGKKM
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEEECCCCHHHHHHH
LADSGLPIISADSMEEAAQKVVAAAAGK
HHCCCCCEEECCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKIHEYQGKEILRKFGVAVPRGKPAFSVDEAVKVAEELGGPVWVVKAQIHAGGRGKGGGV
CCCCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCH
KVAKSIEQVREYANQILGMQLVTHQTGPEGQKVNRLMIEEGADIKQELYVSLVVDRISQK
HHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCE
IVLMGSSEGGMDIEEVAEKHPELIHKVIVEPSTGLLDAQADDLAAKIGVPAASIPQARAI
EEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHH
LQGLYKAFWETDASLAEINPLNVSGDGKVTALDAKFNFDSNALFRHPEIVAYRDLDEEDP
HHHHHHHHHCCCCCHHCCCCEEECCCCCEEEEEEEECCCCCCEECCCCEEEECCCCCCCC
AEIEASKFDLAYISLDGNIGCLVNGAGLAMATMDTIKLFGGEPANFLDVGGGATTEKVTE
CCCCCCEEEEEEEEECCCEEEEEECCCEEEHHHHHHHHCCCCCCCEEECCCCCCHHHHHH
AFKLMLKNPDLKAILVNIFGGIMRCDVIAEGVIAGSKAVNLNVPLVVRMKGTNEDLGKKM
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEEECCCCHHHHHHH
LADSGLPIISADSMEEAAQKVVAAAAGK
HHCCCCCEEECCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA