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The map label for this gene is ygfU [H]

Identifier: 116690626

GI number: 116690626

Start: 2884961

End: 2886337

Strand: Direct

Name: ygfU [H]

Synonym: Bcen2424_2606

Alternate gene names: 116690626

Gene position: 2884961-2886337 (Clockwise)

Preceding gene: 116690622

Following gene: 116690630

Centisome position: 82.81

GC content: 65.65

Gene sequence:

>1377_bases
ATGCAATCGAACACGGTCCATCCGTGCGATGAGGTGCTGCCGACCGGCAAGCTGGTAACGCTTGGCCTGCAACACGTCCT
CGTCATGTACGCCGGCGCCGTCGCCGTGCCGCTTATCGTCGGCGCGGCGCTCAAGCTGCCGAAAGACCAGATCGCGTTCC
TGATCAGCGCCGATCTGTTTTCGTGCGGCATCGCCACGCTGATCCAGACACTCGGCCTGTGGATCTTCGGCATCCGCCTG
CCCGTCATCATGGGCTGCACGTTCGCGGCCGTCGGCCCGATGATCGCGATCGGCACGAACCCCGGCCTCGGCATTCTCGA
CATCTTCGGTTCGACCATCGCCGCCGGCATCATCGGCATCGTGCTCGCGCCGATGATCGGCAAGCTGTTGCGGTTCTTCC
CGCCCGTGGTCGTCGGCACGGTGATCGCCGTGATCGGGCTGTCGCTGATGGAAGTGGGCATCAACTGGGCGGCCGGCGGC
GTCGGCAACCCCGAATACGGCAGCCCCGTCTATCTCGGCCTGTCGCTGCTCGTGCTCACGCTGATCCTGCTGATCAACAA
GTTCGGCCGCGGTTTCGTCGCGAACATCTCGGTGCTGCTCGGCATCGTCGCCGGCTTCGTGATCGCCTTCGCGCTCGGCC
GCGTGAACACCGACGGCGTCGCGCATGCGCCGTGGGTCGGTTTCGTGATGCCGTTCCACTTCGGTCTGCCGCACTTCGAT
CCGCTGTCGATCGTGACGATGGTCACGGTGATGTTCGTCACGTTCATCGAATCCACCGGCATGTTCCTCGCGGTGGGCGA
CATGGTCGATCGCCCGGTCAACCAGGAGCGCCTCGTGCGCGGCCTGCGCGTCGACGGCCTCGGCACGCTGATCGGCGGCA
TCTTCAACTCGTTCCCGCATACGTCGTTCTCGCAGAACGTCGGCCTGATCGGCGTGACGGGCGTGAAGAGCCGCTTCGTG
TGCGCGACGGGCGGCGTGATCCTCGTGCTGCTCGGCCTGTTCCCGAAGATGGCGCAGGTCGTCGCGTCGGTGCCGCCGTT
CGTGCTCGGCGGCGCAGGCATCGTGATGTTCGGGATGGTCGCCGCGAACGGCATCAAGGTGCTGTCGAAGGTCGACTTCG
TGCAGAACTCGCACAACCTGTTCATCGTCGCGGTGAGCGTCGGCATGGGCCTCGTGCCGGTCGTGTCGCCGCACTTCTTC
TCGAAGCTGCCGCCCGCGCTCGCACCGATCCTGCACAGCGGCATCCTGCTGGCATCGGCCACGGCCGTGATCCTGAACAT
CGTGTTCAACGGCGTGAAAGGCGAAAAGGATGCGCGCTGCGAGATTCGGCGCGCGGGGCACGATTTCGATGGGCGGCCCG
CCGACGTGCACCACTGA

Upstream 100 bases:

>100_bases
GAACCAGCAAAGAACGGAATAGAACCCAGTGCTCTTGTTGCATGGATTCATTCCGAATAACTTCGTATCACCCCGAAAAC
AAGATCATGGAGTGAGACAG

Downstream 100 bases:

>100_bases
TCGCGCCGCGCCGGACGATGGCGCGAAGCGGTAACGAAAAACGCCACGGCATGCCGTGGCGTTTTGCTTGATTTCCCGCA
CGATCCGGCAGCGCAAAAGA

Product: uracil-xanthine permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MQSNTVHPCDEVLPTGKLVTLGLQHVLVMYAGAVAVPLIVGAALKLPKDQIAFLISADLFSCGIATLIQTLGLWIFGIRL
PVIMGCTFAAVGPMIAIGTNPGLGILDIFGSTIAAGIIGIVLAPMIGKLLRFFPPVVVGTVIAVIGLSLMEVGINWAAGG
VGNPEYGSPVYLGLSLLVLTLILLINKFGRGFVANISVLLGIVAGFVIAFALGRVNTDGVAHAPWVGFVMPFHFGLPHFD
PLSIVTMVTVMFVTFIESTGMFLAVGDMVDRPVNQERLVRGLRVDGLGTLIGGIFNSFPHTSFSQNVGLIGVTGVKSRFV
CATGGVILVLLGLFPKMAQVVASVPPFVLGGAGIVMFGMVAANGIKVLSKVDFVQNSHNLFIVAVSVGMGLVPVVSPHFF
SKLPPALAPILHSGILLASATAVILNIVFNGVKGEKDARCEIRRAGHDFDGRPADVHH

Sequences:

>Translated_458_residues
MQSNTVHPCDEVLPTGKLVTLGLQHVLVMYAGAVAVPLIVGAALKLPKDQIAFLISADLFSCGIATLIQTLGLWIFGIRL
PVIMGCTFAAVGPMIAIGTNPGLGILDIFGSTIAAGIIGIVLAPMIGKLLRFFPPVVVGTVIAVIGLSLMEVGINWAAGG
VGNPEYGSPVYLGLSLLVLTLILLINKFGRGFVANISVLLGIVAGFVIAFALGRVNTDGVAHAPWVGFVMPFHFGLPHFD
PLSIVTMVTVMFVTFIESTGMFLAVGDMVDRPVNQERLVRGLRVDGLGTLIGGIFNSFPHTSFSQNVGLIGVTGVKSRFV
CATGGVILVLLGLFPKMAQVVASVPPFVLGGAGIVMFGMVAANGIKVLSKVDFVQNSHNLFIVAVSVGMGLVPVVSPHFF
SKLPPALAPILHSGILLASATAVILNIVFNGVKGEKDARCEIRRAGHDFDGRPADVHH
>Mature_458_residues
MQSNTVHPCDEVLPTGKLVTLGLQHVLVMYAGAVAVPLIVGAALKLPKDQIAFLISADLFSCGIATLIQTLGLWIFGIRL
PVIMGCTFAAVGPMIAIGTNPGLGILDIFGSTIAAGIIGIVLAPMIGKLLRFFPPVVVGTVIAVIGLSLMEVGINWAAGG
VGNPEYGSPVYLGLSLLVLTLILLINKFGRGFVANISVLLGIVAGFVIAFALGRVNTDGVAHAPWVGFVMPFHFGLPHFD
PLSIVTMVTVMFVTFIESTGMFLAVGDMVDRPVNQERLVRGLRVDGLGTLIGGIFNSFPHTSFSQNVGLIGVTGVKSRFV
CATGGVILVLLGLFPKMAQVVASVPPFVLGGAGIVMFGMVAANGIKVLSKVDFVQNSHNLFIVAVSVGMGLVPVVSPHFF
SKLPPALAPILHSGILLASATAVILNIVFNGVKGEKDARCEIRRAGHDFDGRPADVHH

Specific function: Unknown

COG id: COG2233

COG function: function code F; Xanthine/uracil permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily [H]

Homologues:

Organism=Homo sapiens, GI44680148, Length=517, Percent_Identity=26.1121856866538, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI40316845, Length=517, Percent_Identity=26.1121856866538, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI44680145, Length=485, Percent_Identity=25.979381443299, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI44680143, Length=489, Percent_Identity=25.7668711656442, Blast_Score=115, Evalue=7e-26,
Organism=Homo sapiens, GI222080105, Length=468, Percent_Identity=23.0769230769231, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI222080107, Length=476, Percent_Identity=22.6890756302521, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI87082181, Length=441, Percent_Identity=58.7301587301587, Blast_Score=520, Evalue=1e-148,
Organism=Escherichia coli, GI1790087, Length=443, Percent_Identity=30.2483069977427, Blast_Score=182, Evalue=4e-47,
Organism=Escherichia coli, GI87082178, Length=457, Percent_Identity=29.7592997811816, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1788843, Length=384, Percent_Identity=28.3854166666667, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI87081818, Length=409, Percent_Identity=30.5623471882641, Blast_Score=129, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI17558856, Length=509, Percent_Identity=26.1296660117878, Blast_Score=98, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI17541904, Length=464, Percent_Identity=23.2758620689655, Blast_Score=88, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17542262, Length=453, Percent_Identity=25.60706401766, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17542260, Length=197, Percent_Identity=27.4111675126904, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71993493, Length=197, Percent_Identity=27.9187817258883, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI21356175, Length=440, Percent_Identity=25.4545454545455, Blast_Score=96, Evalue=5e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017588
- InterPro:   IPR006042
- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 47833; Mature: 47833

Theoretical pI: Translated: 8.76; Mature: 8.76

Prosite motif: PS01116 XANTH_URACIL_PERMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSNTVHPCDEVLPTGKLVTLGLQHVLVMYAGAVAVPLIVGAALKLPKDQIAFLISADLF
CCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
SCGIATLIQTLGLWIFGIRLPVIMGCTFAAVGPMIAIGTNPGLGILDIFGSTIAAGIIGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHHH
VLAPMIGKLLRFFPPVVVGTVIAVIGLSLMEVGINWAAGGVGNPEYGSPVYLGLSLLVLT
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHH
LILLINKFGRGFVANISVLLGIVAGFVIAFALGRVNTDGVAHAPWVGFVMPFHFGLPHFD
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCC
PLSIVTMVTVMFVTFIESTGMFLAVGDMVDRPVNQERLVRGLRVDGLGTLIGGIFNSFPH
HHHHHHHHHHHHHHHHHCCCCEEEECHHHCCCCCHHHHHHHCCCCHHHHHHHHHHHCCCC
TSFSQNVGLIGVTGVKSRFVCATGGVILVLLGLFPKMAQVVASVPPFVLGGAGIVMFGMV
CCCCCCCCEEEECCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCHHCCCHHHHHHHHH
AANGIKVLSKVDFVQNSHNLFIVAVSVGMGLVPVVSPHFFSKLPPALAPILHSGILLASA
HHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHCCCHHHHHCCHHHHHHHHHHHHHHHH
TAVILNIVFNGVKGEKDARCEIRRAGHDFDGRPADVHH
HHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure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HHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]