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The map label for this gene is argF

Identifier: 116690573

GI number: 116690573

Start: 2828882

End: 2829811

Strand: Direct

Name: argF

Synonym: Bcen2424_2553

Alternate gene names: 116690573

Gene position: 2828882-2829811 (Clockwise)

Preceding gene: 116690571

Following gene: 116690575

Centisome position: 81.2

GC content: 62.9

Gene sequence:

>930_bases
ATGACCGCCAAAACCATTCGTCACTACCTGCAGTTCAAGGATTTCTCGCTGGAAGACTACGAGTACGTGCTCGAACGCAC
GGGTATCCTGAAGCGCAAGTTCAAGAACTACGAAACCTATCACCCGCTGCACGACCGCACGCTCGCGATGATCTTCGAGA
AGAGCTCGACGCGTACGCGCCTGTCGTTCGAGGCCGGGATCTTCCAGCTCGGCGGCCACGCCGTGTTCATGAGCACGCGC
GACACGCAGCTCGGCCGCGGCGAGCCCGTCGAGGATTCCGCGCAGGTCATCTCGCGAATGGTCGACATCATCATGATCCG
CACGTTCGAGCAGGACGTGATCACGCGCTTCGCACAGAATTCCCGCGTGCCGGTGATCAACGGGTTGACGAACGAATACC
ATCCGTGCCAGGTGCTCGCCGACATCTTCACGTACTACGAGCACCGCGGCCCGATCGCCGGCAAGACCGTCGCGTGGGTC
GGCGACGCGAACAACATGCTCTACACGTGGATCGAGGCCGCGCAGATCCTCGGCTTCAAGCTGCGCCTGTCGACGCCGCC
CGGCTATGCGCTCGACATGAAGCTCGTGTCGCCCGACAGCGCGCCGTTCTACGAGGTGTTCGACGATCCGAACGAAGCGT
GCAAGGGCGCCGATCTCGTGACGACCGACGTGTGGACGAGCATGGGTTTCGAGGCCGAGAACGAGGCGCGCAAGCAGGCA
TTCGCCGACTGGTGCGTCGACGAGGAAATGATGGGCCATGCGAATCCGGATGCCCTCTTCATGCACTGCCTGCCCGCGCA
CCGCGGCGAGGAAGTGACGGCCGGCGTGATCGACGGCCCGCAGAGTGTCGTGTGGGACGAAGCGGAAAACCGCCTGCACG
TGCAGAAGGCGCTGATGGAATTCCTGCTGCTCGGCCGCCTCAAGCACTGA

Upstream 100 bases:

>100_bases
GTCAAAGCACAGAAAATCCTTTATGCTGCTTTGAGTTATCCACACCCGACGGCGGCGCCGTCCGGCCTCGCGGCCGGGTG
AGACCGCCGTATTTCGTTTC

Downstream 100 bases:

>100_bases
CGCGCCGCTCAACGCACACGCGTAAAAAAAGCGCCGGTCGACGATCGGCGCTTTCGTTTGGGCGCGCCAAAACCGGCGCG
CGCTACGTTACAGGCAGACC

Product: ornithine carbamoyltransferase

Products: NA

Alternate protein names: OTCase

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MTAKTIRHYLQFKDFSLEDYEYVLERTGILKRKFKNYETYHPLHDRTLAMIFEKSSTRTRLSFEAGIFQLGGHAVFMSTR
DTQLGRGEPVEDSAQVISRMVDIIMIRTFEQDVITRFAQNSRVPVINGLTNEYHPCQVLADIFTYYEHRGPIAGKTVAWV
GDANNMLYTWIEAAQILGFKLRLSTPPGYALDMKLVSPDSAPFYEVFDDPNEACKGADLVTTDVWTSMGFEAENEARKQA
FADWCVDEEMMGHANPDALFMHCLPAHRGEEVTAGVIDGPQSVVWDEAENRLHVQKALMEFLLLGRLKH

Sequences:

>Translated_309_residues
MTAKTIRHYLQFKDFSLEDYEYVLERTGILKRKFKNYETYHPLHDRTLAMIFEKSSTRTRLSFEAGIFQLGGHAVFMSTR
DTQLGRGEPVEDSAQVISRMVDIIMIRTFEQDVITRFAQNSRVPVINGLTNEYHPCQVLADIFTYYEHRGPIAGKTVAWV
GDANNMLYTWIEAAQILGFKLRLSTPPGYALDMKLVSPDSAPFYEVFDDPNEACKGADLVTTDVWTSMGFEAENEARKQA
FADWCVDEEMMGHANPDALFMHCLPAHRGEEVTAGVIDGPQSVVWDEAENRLHVQKALMEFLLLGRLKH
>Mature_308_residues
TAKTIRHYLQFKDFSLEDYEYVLERTGILKRKFKNYETYHPLHDRTLAMIFEKSSTRTRLSFEAGIFQLGGHAVFMSTRD
TQLGRGEPVEDSAQVISRMVDIIMIRTFEQDVITRFAQNSRVPVINGLTNEYHPCQVLADIFTYYEHRGPIAGKTVAWVG
DANNMLYTWIEAAQILGFKLRLSTPPGYALDMKLVSPDSAPFYEVFDDPNEACKGADLVTTDVWTSMGFEAENEARKQAF
ADWCVDEEMMGHANPDALFMHCLPAHRGEEVTAGVIDGPQSVVWDEAENRLHVQKALMEFLLLGRLKH

Specific function: Arginine biosynthesis; sixth step. [C]

COG id: COG0078

COG function: function code E; Ornithine carbamoyltransferase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATCase/OTCase family

Homologues:

Organism=Homo sapiens, GI38788445, Length=304, Percent_Identity=39.1447368421053, Blast_Score=218, Evalue=7e-57,
Organism=Homo sapiens, GI18105007, Length=306, Percent_Identity=25.4901960784314, Blast_Score=99, Evalue=6e-21,
Organism=Escherichia coli, GI1786469, Length=325, Percent_Identity=37.5384615384615, Blast_Score=194, Evalue=7e-51,
Organism=Escherichia coli, GI1790703, Length=325, Percent_Identity=35.6923076923077, Blast_Score=191, Evalue=6e-50,
Organism=Escherichia coli, GI2367364, Length=312, Percent_Identity=28.525641025641, Blast_Score=84, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI193204318, Length=296, Percent_Identity=27.027027027027, Blast_Score=84, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6322373, Length=323, Percent_Identity=33.1269349845201, Blast_Score=193, Evalue=2e-50,
Organism=Saccharomyces cerevisiae, GI6322331, Length=315, Percent_Identity=24.1269841269841, Blast_Score=78, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24642586, Length=321, Percent_Identity=26.4797507788162, Blast_Score=97, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OTC_BURCA (Q1BU60)

Other databases:

- EMBL:   CP000378
- RefSeq:   YP_621818.1
- ProteinModelPortal:   Q1BU60
- SMR:   Q1BU60
- STRING:   Q1BU60
- GeneID:   4092475
- GenomeReviews:   CP000378_GR
- KEGG:   bcn:Bcen_1942
- eggNOG:   COG0078
- HOGENOM:   HBG579429
- OMA:   CVVTDTW
- ProtClustDB:   PRK00779
- BioCyc:   BCEN331271:BCEN_1942-MONOMER
- HAMAP:   MF_01109
- InterPro:   IPR006132
- InterPro:   IPR006130
- InterPro:   IPR006131
- InterPro:   IPR002292
- PRINTS:   PR00100
- PRINTS:   PR00102
- TIGRFAMs:   TIGR00658

Pfam domain/function: PF00185 OTCace; PF02729 OTCace_N; SSF53671 Asp/Orn_carbamoyltranf

EC number: =2.1.3.3

Molecular weight: Translated: 35240; Mature: 35109

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: PS00097 CARBAMOYLTRANSFERASE

Important sites: BINDING 107-107 BINDING 134-134

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAKTIRHYLQFKDFSLEDYEYVLERTGILKRKFKNYETYHPLHDRTLAMIFEKSSTRTR
CCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCEE
LSFEAGIFQLGGHAVFMSTRDTQLGRGEPVEDSAQVISRMVDIIMIRTFEQDVITRFAQN
EEECCCCEEECCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SRVPVINGLTNEYHPCQVLADIFTYYEHRGPIAGKTVAWVGDANNMLYTWIEAAQILGFK
CCCCEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHEEE
LRLSTPPGYALDMKLVSPDSAPFYEVFDDPNEACKGADLVTTDVWTSMGFEAENEARKQA
EEECCCCCCEEEEEEECCCCCCCHHCCCCHHHHHCCCCEEEHHHHHHCCCCCHHHHHHHH
FADWCVDEEMMGHANPDALFMHCLPAHRGEEVTAGVIDGPQSVVWDEAENRLHVQKALME
HHHHCCCHHHHCCCCCCCEEEEECCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHH
FLLLGRLKH
HHHHHHCCC
>Mature Secondary Structure 
TAKTIRHYLQFKDFSLEDYEYVLERTGILKRKFKNYETYHPLHDRTLAMIFEKSSTRTR
CHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCEE
LSFEAGIFQLGGHAVFMSTRDTQLGRGEPVEDSAQVISRMVDIIMIRTFEQDVITRFAQN
EEECCCCEEECCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SRVPVINGLTNEYHPCQVLADIFTYYEHRGPIAGKTVAWVGDANNMLYTWIEAAQILGFK
CCCCEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHEEE
LRLSTPPGYALDMKLVSPDSAPFYEVFDDPNEACKGADLVTTDVWTSMGFEAENEARKQA
EEECCCCCCEEEEEEECCCCCCCHHCCCCHHHHHCCCCEEEHHHHHHCCCCCHHHHHHHH
FADWCVDEEMMGHANPDALFMHCLPAHRGEEVTAGVIDGPQSVVWDEAENRLHVQKALME
HHHHCCCHHHHCCCCCCCEEEEECCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHH
FLLLGRLKH
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA