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The map label for this gene is 116690559

Identifier: 116690559

GI number: 116690559

Start: 2815394

End: 2816524

Strand: Reverse

Name: 116690559

Synonym: Bcen2424_2539

Alternate gene names: NA

Gene position: 2816524-2815394 (Counterclockwise)

Preceding gene: 116690560

Following gene: 116690558

Centisome position: 80.84

GC content: 73.65

Gene sequence:

>1131_bases
ATGGCGGCGCGCATTCGCATGTCTGATGCGTCGGCCGGGCCGGTCTGCGTATTCGGCGCGGGCGCGATCGGGTGCTACCT
CGGCGGCCGCCTCGCGGCAGCCGGCGCGCACGTCACGCTCGTCGGCCGCGCGCGGATCGGCGACGCGATTCATCTGCACG
GACTCACGCTGACCGACCGGCGCGGCTATCGCGGGGCGCTCGCGCCGGCCGATGTCCGATTCGCCACCGATCCGGCCGCG
GCGGCCGCCGCGCGGCTCGTGCTCGTCGCGGTGAAGTCGGCCGCCACGCGCGAGGCCGCCGCGCAACTGGCCGGCGTGCT
GCGGCCGGGCACGATCATGATCAGCTTCCAGAACGGCCTGCACAACGCCGACGTGCTGCGCGACGCACTCCCGCAAGCGA
CCGTGTTGGCCGGCATGGTGCCGTTCAACGTGATCGAGCGCGGGCCCGGCGCGTTTCACCAGGGCTCGGCGGGGAGGCTG
GCGGTCGACGCGTCGCCTGCGCTGCAGCCGTTCACCGGCCTGTTCGCGCGGGCCGGCCTGCCGCTCGTGCTGCATCGCGA
CATGCGCACCGTGCAGTGGGCGAAGCTGCTGCTCAACCTGAACAATGCGGTCAATGCGCTCGCGAACCTGCCGTTGCGTG
ACGAGCTCGCCCAACGCACGTACCGGCGCTGCGTCGCATTGGCCCAGCGCGAGGCGCTGCACTGGCTGGCGCGGGCCGCG
ATCCGGCCTGCGCGCTTGACGCCGCTGCCGGCCGCATGGATTCCGGCGATGCTCGATCTGCCCGATGCGGCTTTCCGCGT
GCTCGGCGGCCGGATGCTCGAGATCGATCCGTTGGCGCGCTCGTCGATGTCCGACGATCTCGCGGCGCATCGTGCGACCG
AAGTCGAATGGATCAACGGCGAAATCGTGCGGCTGGCCGGGCGCTTCGGCGCGCCGGCGCCCCGGCGCCGGTCAATGCGC
GGCTGTGCGCGCTCGTCCACGACGCGGAAAGCGCGGCGTCACGTCCGGTGTGGCGCGGCGATGCGCTGTGGGCCGACCTG
GCCGCGCAGGCGCCGCGTGCGGGCCACGTGCCGGCCGCGTAGGCCGGCGTCGCGGCGCTTGCCGACGGCGCGGGCTGGGC
GCAACGACTAA

Upstream 100 bases:

>100_bases
CTGATCGTCGGGCCGCTGTTCGTCGTCGCCGAGGTCGCGTTCTTCGTGGGGCTGCGCGGCGACGTACGCCGCGAAGTCGA
GCGGCGCGCGGGCCCGGTGC

Downstream 100 bases:

>100_bases
GATGCGGAGTGCGTCATCCGACGCCCTTGCGGAGCAATCGCCATGGTGGATCGCCCAACTCTCGATGCCTACGACGCCCA
TGCCGCGCAATACGCGCAGG

Product: 2-dehydropantoate 2-reductase

Products: NA

Alternate protein names: Ketopantoate reductase; KPA reductase; KPR [H]

Number of amino acids: Translated: 376; Mature: 375

Protein sequence:

>376_residues
MAARIRMSDASAGPVCVFGAGAIGCYLGGRLAAAGAHVTLVGRARIGDAIHLHGLTLTDRRGYRGALAPADVRFATDPAA
AAAARLVLVAVKSAATREAAAQLAGVLRPGTIMISFQNGLHNADVLRDALPQATVLAGMVPFNVIERGPGAFHQGSAGRL
AVDASPALQPFTGLFARAGLPLVLHRDMRTVQWAKLLLNLNNAVNALANLPLRDELAQRTYRRCVALAQREALHWLARAA
IRPARLTPLPAAWIPAMLDLPDAAFRVLGGRMLEIDPLARSSMSDDLAAHRATEVEWINGEIVRLAGRFGAPAPRRRSMR
GCARSSTTRKARRHVRCGAAMRCGPTWPRRRRVRATCRPRRPASRRLPTARAGRND

Sequences:

>Translated_376_residues
MAARIRMSDASAGPVCVFGAGAIGCYLGGRLAAAGAHVTLVGRARIGDAIHLHGLTLTDRRGYRGALAPADVRFATDPAA
AAAARLVLVAVKSAATREAAAQLAGVLRPGTIMISFQNGLHNADVLRDALPQATVLAGMVPFNVIERGPGAFHQGSAGRL
AVDASPALQPFTGLFARAGLPLVLHRDMRTVQWAKLLLNLNNAVNALANLPLRDELAQRTYRRCVALAQREALHWLARAA
IRPARLTPLPAAWIPAMLDLPDAAFRVLGGRMLEIDPLARSSMSDDLAAHRATEVEWINGEIVRLAGRFGAPAPRRRSMR
GCARSSTTRKARRHVRCGAAMRCGPTWPRRRRVRATCRPRRPASRRLPTARAGRND
>Mature_375_residues
AARIRMSDASAGPVCVFGAGAIGCYLGGRLAAAGAHVTLVGRARIGDAIHLHGLTLTDRRGYRGALAPADVRFATDPAAA
AAARLVLVAVKSAATREAAAQLAGVLRPGTIMISFQNGLHNADVLRDALPQATVLAGMVPFNVIERGPGAFHQGSAGRLA
VDASPALQPFTGLFARAGLPLVLHRDMRTVQWAKLLLNLNNAVNALANLPLRDELAQRTYRRCVALAQREALHWLARAAI
RPARLTPLPAAWIPAMLDLPDAAFRVLGGRMLEIDPLARSSMSDDLAAHRATEVEWINGEIVRLAGRFGAPAPRRRSMRG
CARSSTTRKARRHVRCGAAMRCGPTWPRRRRVRATCRPRRPASRRLPTARAGRND

Specific function: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid [H]

COG id: COG1893

COG function: function code H; Ketopantoate reductase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ketopantoate reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR003710
- InterPro:   IPR013752
- InterPro:   IPR013332
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02558 ApbA; PF08546 ApbA_C [H]

EC number: =1.1.1.169 [H]

Molecular weight: Translated: 40350; Mature: 40218

Theoretical pI: Translated: 12.24; Mature: 12.24

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAARIRMSDASAGPVCVFGAGAIGCYLGGRLAAAGAHVTLVGRARIGDAIHLHGLTLTDR
CCCEEEECCCCCCCEEEECCCHHHHHHCCHHEECCCEEEEEECCCCCCEEEEECEEEECC
RGYRGALAPADVRFATDPAAAAAARLVLVAVKSAATREAAAQLAGVLRPGTIMISFQNGL
CCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCC
HNADVLRDALPQATVLAGMVPFNVIERGPGAFHQGSAGRLAVDASPALQPFTGLFARAGL
CHHHHHHHHCCHHHHHHHHCCHHHHHCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHCCC
PLVLHRDMRTVQWAKLLLNLNNAVNALANLPLRDELAQRTYRRCVALAQREALHWLARAA
CEEEECCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IRPARLTPLPAAWIPAMLDLPDAAFRVLGGRMLEIDPLARSSMSDDLAAHRATEVEWING
CCCCCCCCCCHHHHHHHHCCCHHHHHHHCCEEEEECHHHHCCCHHHHHHHHCCCEEECCC
EIVRLAGRFGAPAPRRRSMRGCARSSTTRKARRHVRCGAAMRCGPTWPRRRRVRATCRPR
EEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCC
RPASRRLPTARAGRND
CCHHHCCCCCCCCCCC
>Mature Secondary Structure 
AARIRMSDASAGPVCVFGAGAIGCYLGGRLAAAGAHVTLVGRARIGDAIHLHGLTLTDR
CCEEEECCCCCCCEEEECCCHHHHHHCCHHEECCCEEEEEECCCCCCEEEEECEEEECC
RGYRGALAPADVRFATDPAAAAAARLVLVAVKSAATREAAAQLAGVLRPGTIMISFQNGL
CCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCC
HNADVLRDALPQATVLAGMVPFNVIERGPGAFHQGSAGRLAVDASPALQPFTGLFARAGL
CHHHHHHHHCCHHHHHHHHCCHHHHHCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHCCC
PLVLHRDMRTVQWAKLLLNLNNAVNALANLPLRDELAQRTYRRCVALAQREALHWLARAA
CEEEECCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IRPARLTPLPAAWIPAMLDLPDAAFRVLGGRMLEIDPLARSSMSDDLAAHRATEVEWING
CCCCCCCCCCHHHHHHHHCCCHHHHHHHCCEEEEECHHHHCCCHHHHHHHHCCCEEECCC
EIVRLAGRFGAPAPRRRSMRGCARSSTTRKARRHVRCGAAMRCGPTWPRRRRVRATCRPR
EEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCC
RPASRRLPTARAGRND
CCHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11259647 [H]