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The map label for this gene is yeaE [H]

Identifier: 116690551

GI number: 116690551

Start: 2806767

End: 2807612

Strand: Reverse

Name: yeaE [H]

Synonym: Bcen2424_2531

Alternate gene names: 116690551

Gene position: 2807612-2806767 (Counterclockwise)

Preceding gene: 116690553

Following gene: 116690544

Centisome position: 80.59

GC content: 68.44

Gene sequence:

>846_bases
ATGACAGACACGATCGCCACGGTCGTCTTGCCGAACGGCGAGACGATTCCGAAGCTGGGCCTGGGCACCTGGGAAATGGG
CGAGCGGCCGGCGCGGCGCGCGGACGAGATCGCCGCGCTGCGCGAAGGCATCGAACTCGGGATGACGCTGGTCGATACAG
CCGAGATGTACGGCGACGGTGCGACCGAGGAACTCGTCGGCGACGCGCTCGCCGGCTTGCGCGACGACGTGTTCCTCGTC
AGCAAGGTCTACCCGCACCATGCGAGCCGGCGTGGCGTCGTCGCCGCGTGCGACGCGAGCCTCAAGCGCCTGCGTACCGA
TCGCCTCGATCTATACCTGCTGCACTGGCGCGGTTCGGTGCCGCTCGCGGAAACGGTCGAGGGCTTCGACGCGTTGCAGC
GCGCGGGCAAGATCCGCCACTGGGGCGTGAGCAACTTCGATACGGCCGACATGGCCGAACTCGTCGACGAGGCGGGCGGC
GGTGCGTGCGCAACCAACCAGATTCTCTACAACATCGCGCGACGCGGCCCGGAATTCGACCTGCTGCCGTGGCTGGCCGA
CCATCGTATTCCGGCGATGGCGTACAGCCCGGTCGATCACGGGCGGCTGCCGAAACGCTCGCCGCTCGACGAGATCGCGC
GGCTGCGCGGCGTGTCGGTGATGCGCGTCGCGCTGGCGTGGGTGCTCGCGCAGCCGGGCGTATTCGCGATTCCGAAGGCG
TCGCGGATCGAACACGTGCGCGACAACCGCGCCGCGCTCGATGTCGTGTTCAGCGATGACGAGCGCGCGCAGCTTGACGC
ATATTTCCGTCCGCCGCGCAGCAAGCGCGCGCTCGAGATGCTCTGA

Upstream 100 bases:

>100_bases
CCGCGTAATAGGCCGGGGGCGCACCGATTGACTACACTGATGCGTCGTATCCGATGCTTCGGCCGCGATGGGCGGCCACG
AATCCGCGACGAGGACACGC

Downstream 100 bases:

>100_bases
CCGACTTCGGCCGGGCAACGCGTCGGGTCAGTGGTTGCCGCCGGACGATCCGCCGTTGCCGTGACCGCCGCCATTGCCGT
TGCCGGTGCCATGGCCGTTG

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 281; Mature: 280

Protein sequence:

>281_residues
MTDTIATVVLPNGETIPKLGLGTWEMGERPARRADEIAALREGIELGMTLVDTAEMYGDGATEELVGDALAGLRDDVFLV
SKVYPHHASRRGVVAACDASLKRLRTDRLDLYLLHWRGSVPLAETVEGFDALQRAGKIRHWGVSNFDTADMAELVDEAGG
GACATNQILYNIARRGPEFDLLPWLADHRIPAMAYSPVDHGRLPKRSPLDEIARLRGVSVMRVALAWVLAQPGVFAIPKA
SRIEHVRDNRAALDVVFSDDERAQLDAYFRPPRSKRALEML

Sequences:

>Translated_281_residues
MTDTIATVVLPNGETIPKLGLGTWEMGERPARRADEIAALREGIELGMTLVDTAEMYGDGATEELVGDALAGLRDDVFLV
SKVYPHHASRRGVVAACDASLKRLRTDRLDLYLLHWRGSVPLAETVEGFDALQRAGKIRHWGVSNFDTADMAELVDEAGG
GACATNQILYNIARRGPEFDLLPWLADHRIPAMAYSPVDHGRLPKRSPLDEIARLRGVSVMRVALAWVLAQPGVFAIPKA
SRIEHVRDNRAALDVVFSDDERAQLDAYFRPPRSKRALEML
>Mature_280_residues
TDTIATVVLPNGETIPKLGLGTWEMGERPARRADEIAALREGIELGMTLVDTAEMYGDGATEELVGDALAGLRDDVFLVS
KVYPHHASRRGVVAACDASLKRLRTDRLDLYLLHWRGSVPLAETVEGFDALQRAGKIRHWGVSNFDTADMAELVDEAGGG
ACATNQILYNIARRGPEFDLLPWLADHRIPAMAYSPVDHGRLPKRSPLDEIARLRGVSVMRVALAWVLAQPGVFAIPKAS
RIEHVRDNRAALDVVFSDDERAQLDAYFRPPRSKRALEML

Specific function: Unknown

COG id: COG0656

COG function: function code R; Aldo/keto reductases, related to diketogulonate reductase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI24497577, Length=307, Percent_Identity=26.0586319218241, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI5174391, Length=307, Percent_Identity=26.0586319218241, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI223468663, Length=314, Percent_Identity=26.4331210191083, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI310109922, Length=294, Percent_Identity=26.8707482993197, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI5453543, Length=314, Percent_Identity=26.1146496815287, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI310109920, Length=314, Percent_Identity=26.1146496815287, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI45446745, Length=314, Percent_Identity=26.1146496815287, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI4503285, Length=314, Percent_Identity=26.1146496815287, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI24497585, Length=179, Percent_Identity=31.8435754189944, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI223718702, Length=210, Percent_Identity=30, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1788081, Length=272, Percent_Identity=53.3088235294118, Blast_Score=293, Evalue=1e-80,
Organism=Escherichia coli, GI87081735, Length=297, Percent_Identity=29.6296296296296, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1788070, Length=303, Percent_Identity=30.03300330033, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI87082198, Length=269, Percent_Identity=28.6245353159851, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1786400, Length=255, Percent_Identity=26.6666666666667, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1787674, Length=283, Percent_Identity=27.5618374558304, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI48994888, Length=266, Percent_Identity=30.8270676691729, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI1789199, Length=325, Percent_Identity=29.2307692307692, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1789375, Length=313, Percent_Identity=26.8370607028754, Blast_Score=80, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17552492, Length=271, Percent_Identity=26.1992619926199, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17561298, Length=297, Percent_Identity=28.956228956229, Blast_Score=88, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17566692, Length=312, Percent_Identity=24.6794871794872, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17538386, Length=283, Percent_Identity=29.3286219081272, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71998625, Length=286, Percent_Identity=27.6223776223776, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17564128, Length=306, Percent_Identity=27.1241830065359, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17550248, Length=302, Percent_Identity=23.5099337748344, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17561300, Length=282, Percent_Identity=26.9503546099291, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17537077, Length=302, Percent_Identity=24.5033112582781, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17537075, Length=305, Percent_Identity=24.5901639344262, Blast_Score=69, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6324694, Length=297, Percent_Identity=28.956228956229, Blast_Score=94, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6320576, Length=316, Percent_Identity=27.2151898734177, Blast_Score=86, Evalue=7e-18,
Organism=Drosophila melanogaster, GI45553081, Length=302, Percent_Identity=27.4834437086093, Blast_Score=88, Evalue=8e-18,
Organism=Drosophila melanogaster, GI24644950, Length=305, Percent_Identity=25.9016393442623, Blast_Score=81, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24662789, Length=284, Percent_Identity=26.7605633802817, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24663317, Length=302, Percent_Identity=25.1655629139073, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI20129731, Length=308, Percent_Identity=26.2987012987013, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24657054, Length=307, Percent_Identity=24.1042345276873, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI281366140, Length=263, Percent_Identity=26.2357414448669, Blast_Score=68, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 30988; Mature: 30857

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDTIATVVLPNGETIPKLGLGTWEMGERPARRADEIAALREGIELGMTLVDTAEMYGDG
CCCCEEEEEECCCCCCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCC
ATEELVGDALAGLRDDVFLVSKVYPHHASRRGVVAACDASLKRLRTDRLDLYLLHWRGSV
CHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHCCCEEEEEEECCCC
PLAETVEGFDALQRAGKIRHWGVSNFDTADMAELVDEAGGGACATNQILYNIARRGPEFD
CHHHHHHHHHHHHHCCCCEECCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCC
LLPWLADHRIPAMAYSPVDHGRLPKRSPLDEIARLRGVSVMRVALAWVLAQPGVFAIPKA
CCCHHHCCCCCCEEECCCCCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHCCCEEECCCH
SRIEHVRDNRAALDVVFSDDERAQLDAYFRPPRSKRALEML
HHHHHHHCCCEEEEEEECCCCCHHHHHHCCCCCCCHHHHCC
>Mature Secondary Structure 
TDTIATVVLPNGETIPKLGLGTWEMGERPARRADEIAALREGIELGMTLVDTAEMYGDG
CCCEEEEEECCCCCCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCC
ATEELVGDALAGLRDDVFLVSKVYPHHASRRGVVAACDASLKRLRTDRLDLYLLHWRGSV
CHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHCCCEEEEEEECCCC
PLAETVEGFDALQRAGKIRHWGVSNFDTADMAELVDEAGGGACATNQILYNIARRGPEFD
CHHHHHHHHHHHHHCCCCEECCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCC
LLPWLADHRIPAMAYSPVDHGRLPKRSPLDEIARLRGVSVMRVALAWVLAQPGVFAIPKA
CCCHHHCCCCCCEEECCCCCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHCCCEEECCCH
SRIEHVRDNRAALDVVFSDDERAQLDAYFRPPRSKRALEML
HHHHHHHCCCEEEEEEECCCCCHHHHHHCCCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]