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The map label for this gene is ompR [H]

Identifier: 116690421

GI number: 116690421

Start: 2663331

End: 2664056

Strand: Reverse

Name: ompR [H]

Synonym: Bcen2424_2401

Alternate gene names: 116690421

Gene position: 2664056-2663331 (Counterclockwise)

Preceding gene: 116690423

Following gene: 116690420

Centisome position: 76.47

GC content: 70.52

Gene sequence:

>726_bases
ATGACTACCCAGATCCTCATCGTCGACGACGACCAAGAACTCCGAGACCTGCTGCGCGACTATCTCGTGCGCCAGGGGAT
GGAAGTGTCCGTGCTGCACGACGCAGCGACGCTCGAGAAGCGCCTCGAGCGCGAGCGGCCCGACCTGATCGTGCTGGACC
TGATGATGCCGGGCGTGGACGGCCTGACCGCGCTGCGCCAGTTGCGCGCGGCCGGCGACGACATCCCCGTGATCATGCTG
ACCGCGCGGGCGGACGACGTCGACCGCATCGTCGGGCTCGAGCTCGGCGCGGACGACTACCTCGGCAAGCCGTTCAATCC
GCGCGAGCTGCTCGCGCGCGTGCAGGCCGTGCTGCGCCGCCGCCGCGCGACGCCGTCGGCGGCCGCGCCCGAGCAGCGCG
AGCCGTTCGCGTTCGGCCGCTTCCTGCTCGACTTCCAGGCGCGCACGCTGTCGGTCGACGGCAAGCCGGCCACGCTGTCG
AGCAGCGAATTCGCGCTGCTGAAGATCTTCGTGAACCACGCGCTGCGCACGCTCACGCGCGAGCGGCTGCTCGAGCTGCT
GCACGGGCCCGAGTACGACGGCACCGACCGCGGCATCGACGTCCAGGTGTGGCGCCTGCGCCGCATCCTCGAAACGGATC
CGTCGACGCCGCGCTTCATCCAGACGGTCCGCGGGCGCGGCTACGTGTTCGTGCCCGACGGCGAGGCCCATGCGCAAACC
CATTGA

Upstream 100 bases:

>100_bases
TTACCGCGCATTACAGTTCCCTTGCGCGGTAACCCGCAGTAACCCTTTCGCCCCTTTGTTTCGTTCTTCGACTCCGCCCT
CGCGCGGTAAACTTCGAGCC

Downstream 100 bases:

>100_bases
TTCACTGTTCGGGCGGCTGGCGCTGCTCGTCGTCGGTGTCCTGCTCCTGTCGCACTTCGCGTGGTTCTTCGCGATGCGGC
TCGAGCGCAACCAGATGCAG

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 241; Mature: 240

Protein sequence:

>241_residues
MTTQILIVDDDQELRDLLRDYLVRQGMEVSVLHDAATLEKRLERERPDLIVLDLMMPGVDGLTALRQLRAAGDDIPVIML
TARADDVDRIVGLELGADDYLGKPFNPRELLARVQAVLRRRRATPSAAAPEQREPFAFGRFLLDFQARTLSVDGKPATLS
SSEFALLKIFVNHALRTLTRERLLELLHGPEYDGTDRGIDVQVWRLRRILETDPSTPRFIQTVRGRGYVFVPDGEAHAQT
H

Sequences:

>Translated_241_residues
MTTQILIVDDDQELRDLLRDYLVRQGMEVSVLHDAATLEKRLERERPDLIVLDLMMPGVDGLTALRQLRAAGDDIPVIML
TARADDVDRIVGLELGADDYLGKPFNPRELLARVQAVLRRRRATPSAAAPEQREPFAFGRFLLDFQARTLSVDGKPATLS
SSEFALLKIFVNHALRTLTRERLLELLHGPEYDGTDRGIDVQVWRLRRILETDPSTPRFIQTVRGRGYVFVPDGEAHAQT
H
>Mature_240_residues
TTQILIVDDDQELRDLLRDYLVRQGMEVSVLHDAATLEKRLERERPDLIVLDLMMPGVDGLTALRQLRAAGDDIPVIMLT
ARADDVDRIVGLELGADDYLGKPFNPRELLARVQAVLRRRRATPSAAAPEQREPFAFGRFLLDFQARTLSVDGKPATLSS
SEFALLKIFVNHALRTLTRERLLELLHGPEYDGTDRGIDVQVWRLRRILETDPSTPRFIQTVRGRGYVFVPDGEAHAQTH

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=234, Percent_Identity=52.1367521367521, Blast_Score=237, Evalue=5e-64,
Organism=Escherichia coli, GI1786599, Length=232, Percent_Identity=37.9310344827586, Blast_Score=146, Evalue=1e-36,
Organism=Escherichia coli, GI1788394, Length=235, Percent_Identity=39.1489361702128, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1790863, Length=237, Percent_Identity=35.8649789029536, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI2367329, Length=230, Percent_Identity=39.5652173913043, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI145693140, Length=233, Percent_Identity=35.1931330472103, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1786784, Length=233, Percent_Identity=37.3390557939914, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1787229, Length=234, Percent_Identity=35.8974358974359, Blast_Score=132, Evalue=1e-32,
Organism=Escherichia coli, GI1786911, Length=233, Percent_Identity=38.6266094420601, Blast_Score=130, Evalue=8e-32,
Organism=Escherichia coli, GI1790860, Length=226, Percent_Identity=34.9557522123894, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI1789402, Length=227, Percent_Identity=37.0044052863436, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI87082012, Length=228, Percent_Identity=34.2105263157895, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1787375, Length=226, Percent_Identity=29.646017699115, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI1790552, Length=232, Percent_Identity=33.1896551724138, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI1790299, Length=111, Percent_Identity=34.2342342342342, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788550, Length=117, Percent_Identity=35.042735042735, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1787487, Length=101, Percent_Identity=35.6435643564356, Blast_Score=62, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=102, Percent_Identity=34.3137254901961, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27273; Mature: 27141

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTQILIVDDDQELRDLLRDYLVRQGMEVSVLHDAATLEKRLERERPDLIVLDLMMPGVD
CCEEEEEECCCHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHCCCCEEEEEECCCCCH
GLTALRQLRAAGDDIPVIMLTARADDVDRIVGLELGADDYLGKPFNPRELLARVQAVLRR
HHHHHHHHHHCCCCCCEEEEEECCCCHHHHHEEEECCCCCCCCCCCHHHHHHHHHHHHHH
RRATPSAAAPEQREPFAFGRFLLDFQARTLSVDGKPATLSSSEFALLKIFVNHALRTLTR
HCCCCCCCCCCCCCCHHHHHHHHHHHHHEEEECCCCCEECCCCHHHHHHHHHHHHHHHHH
ERLLELLHGPEYDGTDRGIDVQVWRLRRILETDPSTPRFIQTVRGRGYVFVPDGEAHAQT
HHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHCCCCEEEECCCCCCCCC
H
C
>Mature Secondary Structure 
TTQILIVDDDQELRDLLRDYLVRQGMEVSVLHDAATLEKRLERERPDLIVLDLMMPGVD
CEEEEEECCCHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHCCCCEEEEEECCCCCH
GLTALRQLRAAGDDIPVIMLTARADDVDRIVGLELGADDYLGKPFNPRELLARVQAVLRR
HHHHHHHHHHCCCCCCEEEEEECCCCHHHHHEEEECCCCCCCCCCCHHHHHHHHHHHHHH
RRATPSAAAPEQREPFAFGRFLLDFQARTLSVDGKPATLSSSEFALLKIFVNHALRTLTR
HCCCCCCCCCCCCCCHHHHHHHHHHHHHEEEECCCCCEECCCCHHHHHHHHHHHHHHHHH
ERLLELLHGPEYDGTDRGIDVQVWRLRRILETDPSTPRFIQTVRGRGYVFVPDGEAHAQT
HHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHCCCCEEEECCCCCCCCC
H
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]