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The map label for this gene is eco [H]

Identifier: 116690407

GI number: 116690407

Start: 2650684

End: 2651184

Strand: Reverse

Name: eco [H]

Synonym: Bcen2424_2387

Alternate gene names: 116690407

Gene position: 2651184-2650684 (Counterclockwise)

Preceding gene: 116690409

Following gene: 116690405

Centisome position: 76.1

GC content: 69.06

Gene sequence:

>501_bases
ATGACATTCGCGATCCGGGCCGCGCTGGCCGCCCTCTGCGTGACGACCGCCGCCGCATGCGTGGCCGCGCCGGCCTCCGC
GCCCGCCGTGCCGGCCGAGTCGATCAAGATGTTCCCGCAGGCCGCGACCGGCCAGCAGCGCGTCGTGATCGCGCTGCCCG
CGCTCGAGAACGAGGGCGATGCGCGCGTCGAGCTGATGATTGGCAAGACGCTGCAGACCGACTGCAACCAGCAGTGGTTC
GGCGGCGAGCTGACCGCCGAGGACGTGAAGGGCTGGGGCTATACGTATTACCGGCTCACCGACGTAAAGGGGCCGGCATC
GACGCTGATGGCGTGCCCGGGCCAGGCGCCGCAGCAACGGTTCGTGCAGGTGCGCGGCGACGGTCAACTGCTGCGCTACA
ACAGCCGCCTGCCGCTCGTCGTCTATGTACCGGACGGCTTCGACGTGCGTTATCGCGTGTGGCACGCGTCGAAGGACGTG
CAGCAGGCTGCGAAGCAGTAA

Upstream 100 bases:

>100_bases
TGCCGGCTGTTTGCAATTGTGTCGCCAAATTACAGCTTCGTAAGGTCTTGCGACGAAAGTGTTAGCATCCGGGGCTCATT
TGTTTTTCAGGAGCACATCG

Downstream 100 bases:

>100_bases
CCTTTCCTTTCGGCGGCGTCCTGCCGCTACACACTGGCCGCGCTGCTCGTACCGACGAGCGCCGGCCAAGCGGCCAGCGC
GGCCTGCGCAATGGCCTCCA

Product: ecotin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 166; Mature: 165

Protein sequence:

>166_residues
MTFAIRAALAALCVTTAAACVAAPASAPAVPAESIKMFPQAATGQQRVVIALPALENEGDARVELMIGKTLQTDCNQQWF
GGELTAEDVKGWGYTYYRLTDVKGPASTLMACPGQAPQQRFVQVRGDGQLLRYNSRLPLVVYVPDGFDVRYRVWHASKDV
QQAAKQ

Sequences:

>Translated_166_residues
MTFAIRAALAALCVTTAAACVAAPASAPAVPAESIKMFPQAATGQQRVVIALPALENEGDARVELMIGKTLQTDCNQQWF
GGELTAEDVKGWGYTYYRLTDVKGPASTLMACPGQAPQQRFVQVRGDGQLLRYNSRLPLVVYVPDGFDVRYRVWHASKDV
QQAAKQ
>Mature_165_residues
TFAIRAALAALCVTTAAACVAAPASAPAVPAESIKMFPQAATGQQRVVIALPALENEGDARVELMIGKTLQTDCNQQWFG
GELTAEDVKGWGYTYYRLTDVKGPASTLMACPGQAPQQRFVQVRGDGQLLRYNSRLPLVVYVPDGFDVRYRVWHASKDVQ
QAAKQ

Specific function: General inhibitor of family S1 serine proteases [H]

COG id: COG4574

COG function: function code R; Serine protease inhibitor ecotin

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protease inhibitor I11 (ecotin) family [H]

Homologues:

Organism=Escherichia coli, GI1788538, Length=148, Percent_Identity=45.945945945946, Blast_Score=142, Evalue=1e-35,

Paralogues:

None

Copy number: 260 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005658
- InterPro:   IPR023189
- InterPro:   IPR023084 [H]

Pfam domain/function: PF03974 Ecotin [H]

EC number: NA

Molecular weight: Translated: 17989; Mature: 17858

Theoretical pI: Translated: 8.31; Mature: 8.31

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFAIRAALAALCVTTAAACVAAPASAPAVPAESIKMFPQAATGQQRVVIALPALENEGD
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCCCCCEEEEEEECCCCCCC
ARVELMIGKTLQTDCNQQWFGGELTAEDVKGWGYTYYRLTDVKGPASTLMACPGQAPQQR
CEEEEEECCCCCCCCCCCCCCCCCCHHHCCCCCEEEEEEEECCCCHHHHEECCCCCCCHH
FVQVRGDGQLLRYNSRLPLVVYVPDGFDVRYRVWHASKDVQQAAKQ
EEEECCCCEEEEECCCCCEEEECCCCCCEEEEEEECCHHHHHHHCC
>Mature Secondary Structure 
TFAIRAALAALCVTTAAACVAAPASAPAVPAESIKMFPQAATGQQRVVIALPALENEGD
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCCCCCEEEEEEECCCCCCC
ARVELMIGKTLQTDCNQQWFGGELTAEDVKGWGYTYYRLTDVKGPASTLMACPGQAPQQR
CEEEEEECCCCCCCCCCCCCCCCCCHHHCCCCCEEEEEEEECCCCHHHHEECCCCCCCHH
FVQVRGDGQLLRYNSRLPLVVYVPDGFDVRYRVWHASKDVQQAAKQ
EEEECCCCEEEEECCCCCEEEECCCCCCEEEEEEECCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA