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The map label for this gene is fabG [H]

Identifier: 116690313

GI number: 116690313

Start: 2548016

End: 2548795

Strand: Reverse

Name: fabG [H]

Synonym: Bcen2424_2292

Alternate gene names: 116690313

Gene position: 2548795-2548016 (Counterclockwise)

Preceding gene: 116690327

Following gene: 116690312

Centisome position: 73.16

GC content: 71.92

Gene sequence:

>780_bases
ATGGATCTCGGCATCGAAGGAAAGACCGCGCTCGTGTGCGCGGCCAGCAAGGGCCTCGGGCGTGGCTGCGCGGAAGCGCT
GGCCGCCGAGGGCGTGAACCTCGTGATCGTCGCGCGCACGCGCGACACGCTGGAGGAAACCGCGGAAGAGATCCGCGCCG
GCGCGAACGTGTCGGTCACGGCGGTCGCCTGCGACATCACGACGCCGGACGGCCGCGCGGCCGCGCTCGCCGCGTGCCCG
CAGCCGGACATTCTCGTGACGAATGCCGGCGGCCCGCCGCCCGGCGACTTCCGCGACTTCTCGCACGACGACTGGATTCG
CGCGCTCGAGTCGAACATGCTGACGCCGATCGAGCTGATCCGCGCGACCCTCGACGGGATGATCGGCCGCGGCTTCGGCC
GGATCGTCAACATCACGAGTTCGGCCGTGAAGGCGCCGATCGACGTGCTCGCGCTGTCGAACGGCGCGCGCTCGGGGCTG
ACCGGCTTCGTCGCGGGGCTGTCGCGCAAGGTCGCGGGGCAGGGCGTGACGATCAACAACCTGCTGCCGGGGCTGTTCGA
CACCGACCGGATCGCGACGACGCTCGCCGCGTCGGCGCAGGCGCAGGGCGTGACGGTCGACGAGATGCGCGCGCGGCGCA
CCAGGGACATCCCGGCCGGGCGCCTCGGCACGCGCGCCGAGTTCGGCGCGGCCTGTGCGTTCCTGTGCAGCGTGCACACC
GGCTACATCACCGGGCAGAACTGGCTGCTCGACGGCGGCGCGTATCCGGGTACGTTCTGA

Upstream 100 bases:

>100_bases
TCGACGTCTCACGACAATCCGCGTGCCGCGCACGCCCGTTTGCCCGCCGCCGGCGGCCACGCGGGGCCGCGCCGGCATGC
GTGCCACCAGGGAAACGACG

Downstream 100 bases:

>100_bases
CCCGCGCTTTTCGCTTCACGACGACAACAACCGAACGACGAAGGAACTGGAGATGAGCAAACCCCGCATCGCACTGATTG
CGCACGACGCGAAGAAGGAC

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MDLGIEGKTALVCAASKGLGRGCAEALAAEGVNLVIVARTRDTLEETAEEIRAGANVSVTAVACDITTPDGRAAALAACP
QPDILVTNAGGPPPGDFRDFSHDDWIRALESNMLTPIELIRATLDGMIGRGFGRIVNITSSAVKAPIDVLALSNGARSGL
TGFVAGLSRKVAGQGVTINNLLPGLFDTDRIATTLAASAQAQGVTVDEMRARRTRDIPAGRLGTRAEFGAACAFLCSVHT
GYITGQNWLLDGGAYPGTF

Sequences:

>Translated_259_residues
MDLGIEGKTALVCAASKGLGRGCAEALAAEGVNLVIVARTRDTLEETAEEIRAGANVSVTAVACDITTPDGRAAALAACP
QPDILVTNAGGPPPGDFRDFSHDDWIRALESNMLTPIELIRATLDGMIGRGFGRIVNITSSAVKAPIDVLALSNGARSGL
TGFVAGLSRKVAGQGVTINNLLPGLFDTDRIATTLAASAQAQGVTVDEMRARRTRDIPAGRLGTRAEFGAACAFLCSVHT
GYITGQNWLLDGGAYPGTF
>Mature_259_residues
MDLGIEGKTALVCAASKGLGRGCAEALAAEGVNLVIVARTRDTLEETAEEIRAGANVSVTAVACDITTPDGRAAALAACP
QPDILVTNAGGPPPGDFRDFSHDDWIRALESNMLTPIELIRATLDGMIGRGFGRIVNITSSAVKAPIDVLALSNGARSGL
TGFVAGLSRKVAGQGVTINNLLPGLFDTDRIATTLAASAQAQGVTVDEMRARRTRDIPAGRLGTRAEFGAACAFLCSVHT
GYITGQNWLLDGGAYPGTF

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=251, Percent_Identity=27.4900398406374, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI19923817, Length=257, Percent_Identity=25.2918287937743, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI226371731, Length=184, Percent_Identity=28.804347826087, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI7705855, Length=196, Percent_Identity=27.0408163265306, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI40254992, Length=250, Percent_Identity=25.6, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI7705925, Length=257, Percent_Identity=24.5136186770428, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI4503301, Length=260, Percent_Identity=27.6923076923077, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI20149619, Length=203, Percent_Identity=29.064039408867, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI66933014, Length=175, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI126723191, Length=194, Percent_Identity=26.2886597938144, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1787335, Length=264, Percent_Identity=32.9545454545455, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI87082100, Length=258, Percent_Identity=32.1705426356589, Blast_Score=94, Evalue=9e-21,
Organism=Escherichia coli, GI87082160, Length=258, Percent_Identity=29.8449612403101, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1789208, Length=260, Percent_Identity=30, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1788459, Length=253, Percent_Identity=26.4822134387352, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787905, Length=256, Percent_Identity=26.171875, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1790717, Length=256, Percent_Identity=22.265625, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI2367365, Length=252, Percent_Identity=27.3809523809524, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17560676, Length=253, Percent_Identity=24.901185770751, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17561402, Length=255, Percent_Identity=27.0588235294118, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17562904, Length=259, Percent_Identity=28.5714285714286, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17562906, Length=269, Percent_Identity=27.5092936802974, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17562910, Length=262, Percent_Identity=27.4809160305344, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17551412, Length=266, Percent_Identity=28.5714285714286, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17538486, Length=265, Percent_Identity=27.5471698113208, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI72000259, Length=262, Percent_Identity=30.1526717557252, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17508651, Length=253, Percent_Identity=26.0869565217391, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17560150, Length=262, Percent_Identity=27.4809160305344, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17559104, Length=260, Percent_Identity=27.3076923076923, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI193204405, Length=267, Percent_Identity=26.5917602996255, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17538480, Length=264, Percent_Identity=27.2727272727273, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17563726, Length=257, Percent_Identity=26.4591439688716, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI25152911, Length=191, Percent_Identity=29.8429319371728, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17562908, Length=268, Percent_Identity=28.7313432835821, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71994600, Length=253, Percent_Identity=27.6679841897233, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17560332, Length=264, Percent_Identity=27.2727272727273, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17560220, Length=263, Percent_Identity=25.4752851711027, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI21355319, Length=254, Percent_Identity=25.9842519685039, Blast_Score=88, Evalue=7e-18,
Organism=Drosophila melanogaster, GI23397609, Length=257, Percent_Identity=29.9610894941634, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI21357041, Length=253, Percent_Identity=30.8300395256917, Blast_Score=78, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24639444, Length=263, Percent_Identity=27.7566539923954, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24584744, Length=194, Percent_Identity=29.8969072164948, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI28574402, Length=194, Percent_Identity=29.8969072164948, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI28571526, Length=257, Percent_Identity=29.1828793774319, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI21358495, Length=215, Percent_Identity=26.046511627907, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 26725; Mature: 26725

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLGIEGKTALVCAASKGLGRGCAEALAAEGVNLVIVARTRDTLEETAEEIRAGANVSVT
CCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHCCCCEEEE
AVACDITTPDGRAAALAACPQPDILVTNAGGPPPGDFRDFSHDDWIRALESNMLTPIELI
EEEEEEECCCCCEEEEEECCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHH
RATLDGMIGRGFGRIVNITSSAVKAPIDVLALSNGARSGLTGFVAGLSRKVAGQGVTINN
HHHHHHHHHCCCHHEEEECHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCEEHHH
LLPGLFDTDRIATTLAASAQAQGVTVDEMRARRTRDIPAGRLGTRAEFGAACAFLCSVHT
CCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHC
GYITGQNWLLDGGAYPGTF
CEEECCCEEEECCCCCCCC
>Mature Secondary Structure
MDLGIEGKTALVCAASKGLGRGCAEALAAEGVNLVIVARTRDTLEETAEEIRAGANVSVT
CCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHCCCCEEEE
AVACDITTPDGRAAALAACPQPDILVTNAGGPPPGDFRDFSHDDWIRALESNMLTPIELI
EEEEEEECCCCCEEEEEECCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHH
RATLDGMIGRGFGRIVNITSSAVKAPIDVLALSNGARSGLTGFVAGLSRKVAGQGVTINN
HHHHHHHHHCCCHHEEEECHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCEEHHH
LLPGLFDTDRIATTLAASAQAQGVTVDEMRARRTRDIPAGRLGTRAEFGAACAFLCSVHT
CCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHC
GYITGQNWLLDGGAYPGTF
CEEECCCEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]