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The map label for this gene is qor [H]

Identifier: 116690311

GI number: 116690311

Start: 2546424

End: 2547398

Strand: Reverse

Name: qor [H]

Synonym: Bcen2424_2290

Alternate gene names: 116690311

Gene position: 2547398-2546424 (Counterclockwise)

Preceding gene: 116690312

Following gene: 116690310

Centisome position: 73.12

GC content: 68.1

Gene sequence:

>975_bases
ATGCCGAAAGCAATCCGATACGACCAGCCGGGCGGCCCGGACGTGATGAAGTGGGTCGATGTCGAGGTCGGCGCGCCGAA
GGCGGGCGAAGTCCGCATCCGGCAACACGCGGTCGGGCTCAACTACATCGACGTGTATTTCCGCACGGGCCTGTATCCGC
AACAGCTGCCGGCCGGCCTCGGGATGGAGGCGGCGGGCGAGGTGACGGCCGTCGGCGACGGCGTGACCGCGTTCAAGGCC
GGCGACCGTGTCGCCTACGTCGGCCAGCCGCCCGGCGCGTATGCGCAGGAGCGCGTGATGCCGGCCGAGCGTGTCGTGAA
GCTGCCGGACGGCATCAGCTACGACGACGCGGCATCGGTGATGCTGCAGGGCCTGACCGCGCACTATCTGCTGCGCCGCA
CCTACCCGGTGAAGGCCGGCGACACGATCCTGATCCACGCGGCGGCCGGCGGCGTGGGCTTGCTCGTGTGCCAGTGGGCG
AAGGCGCTCGGCGCGACCGTGATCGGTACGGTCGGCTCCGACGAGAAGGCCGAGCTCGCGAAGGCGCACGGCTGCGATCA
TCCGATCGTCTACACGCGCGAGAACTTCACGCAGCGCGTGAAGGCAATCACGAACGGCGCGGGCGTGCCGGTCGTCTACG
ATTCGATCGGCAAGGACACCTACGTCGGTTCGCTCGACAGCCTCGCGCCGCTCGGCTACTTCGTCAGCTTCGGCAATGCG
TCGGGGCCGCTGCCGCCGATCGACTCGAAGGAATTCTCGTCGCGCGGCTCGCTGTTCTTCACGCGACCGACGCTGTTCTC
GTACATCGCGAAGCGCGCCGATCTCGAGGCCGCGGCCGCCGAGCTGTTCGACGTGATCCTGTCGGGCAAGGTGAAGACGA
GCATCAACCAGCGCTATCCGCTCGCCGAAGTCGGCCGCGCGCATGCCGATCTGGAAGCACGCAAGACCACCGGCTCGACG
ATCCTGGTTCCCTGA

Upstream 100 bases:

>100_bases
GCGTCGCCACGCGCGCCTGCCGGCACCCGCACGAATCGGTGCGGCGCGCGCATCGGCGCCCCGGATTTCCCTGACTGACA
GACAGAAGAGGAGCAAAACG

Downstream 100 bases:

>100_bases
CGCATCCTTTCGTGCCGGCGTTACGCCGGCACATCCCGGGCGGCGCCGGCGGGCCGCCCGTCCTGCCTCCTGTCTCCCGG
CCTGTCCGACGTCCCGACCA

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: NADPH:quinone reductase [H]

Number of amino acids: Translated: 324; Mature: 323

Protein sequence:

>324_residues
MPKAIRYDQPGGPDVMKWVDVEVGAPKAGEVRIRQHAVGLNYIDVYFRTGLYPQQLPAGLGMEAAGEVTAVGDGVTAFKA
GDRVAYVGQPPGAYAQERVMPAERVVKLPDGISYDDAASVMLQGLTAHYLLRRTYPVKAGDTILIHAAAGGVGLLVCQWA
KALGATVIGTVGSDEKAELAKAHGCDHPIVYTRENFTQRVKAITNGAGVPVVYDSIGKDTYVGSLDSLAPLGYFVSFGNA
SGPLPPIDSKEFSSRGSLFFTRPTLFSYIAKRADLEAAAAELFDVILSGKVKTSINQRYPLAEVGRAHADLEARKTTGST
ILVP

Sequences:

>Translated_324_residues
MPKAIRYDQPGGPDVMKWVDVEVGAPKAGEVRIRQHAVGLNYIDVYFRTGLYPQQLPAGLGMEAAGEVTAVGDGVTAFKA
GDRVAYVGQPPGAYAQERVMPAERVVKLPDGISYDDAASVMLQGLTAHYLLRRTYPVKAGDTILIHAAAGGVGLLVCQWA
KALGATVIGTVGSDEKAELAKAHGCDHPIVYTRENFTQRVKAITNGAGVPVVYDSIGKDTYVGSLDSLAPLGYFVSFGNA
SGPLPPIDSKEFSSRGSLFFTRPTLFSYIAKRADLEAAAAELFDVILSGKVKTSINQRYPLAEVGRAHADLEARKTTGST
ILVP
>Mature_323_residues
PKAIRYDQPGGPDVMKWVDVEVGAPKAGEVRIRQHAVGLNYIDVYFRTGLYPQQLPAGLGMEAAGEVTAVGDGVTAFKAG
DRVAYVGQPPGAYAQERVMPAERVVKLPDGISYDDAASVMLQGLTAHYLLRRTYPVKAGDTILIHAAAGGVGLLVCQWAK
ALGATVIGTVGSDEKAELAKAHGCDHPIVYTRENFTQRVKAITNGAGVPVVYDSIGKDTYVGSLDSLAPLGYFVSFGNAS
GPLPPIDSKEFSSRGSLFFTRPTLFSYIAKRADLEAAAAELFDVILSGKVKTSINQRYPLAEVGRAHADLEARKTTGSTI
LVP

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI194239674, Length=331, Percent_Identity=32.02416918429, Blast_Score=148, Evalue=7e-36,
Organism=Homo sapiens, GI13236495, Length=331, Percent_Identity=32.02416918429, Blast_Score=148, Evalue=7e-36,
Organism=Homo sapiens, GI194239676, Length=328, Percent_Identity=30.7926829268293, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI22538446, Length=330, Percent_Identity=31.2121212121212, Blast_Score=132, Evalue=3e-31,
Organism=Homo sapiens, GI22538444, Length=330, Percent_Identity=31.2121212121212, Blast_Score=132, Evalue=3e-31,
Organism=Homo sapiens, GI18379349, Length=313, Percent_Identity=29.7124600638978, Blast_Score=131, Evalue=7e-31,
Organism=Homo sapiens, GI24308257, Length=338, Percent_Identity=28.9940828402367, Blast_Score=109, Evalue=3e-24,
Organism=Homo sapiens, GI28557745, Length=292, Percent_Identity=30.4794520547945, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI67078404, Length=245, Percent_Identity=28.1632653061224, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI197927207, Length=198, Percent_Identity=29.7979797979798, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI41872631, Length=212, Percent_Identity=30.188679245283, Blast_Score=65, Evalue=8e-11,
Organism=Homo sapiens, GI67078406, Length=195, Percent_Identity=29.2307692307692, Blast_Score=65, Evalue=9e-11,
Organism=Escherichia coli, GI1790485, Length=327, Percent_Identity=46.7889908256881, Blast_Score=298, Evalue=5e-82,
Organism=Escherichia coli, GI87082125, Length=349, Percent_Identity=26.0744985673352, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI87081918, Length=324, Percent_Identity=25.9259259259259, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17507255, Length=318, Percent_Identity=26.7295597484277, Blast_Score=105, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI17556000, Length=209, Percent_Identity=32.5358851674641, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17536829, Length=242, Percent_Identity=28.099173553719, Blast_Score=65, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6319520, Length=324, Percent_Identity=40.7407407407407, Blast_Score=224, Evalue=1e-59,
Organism=Saccharomyces cerevisiae, GI6323729, Length=351, Percent_Identity=25.3561253561254, Blast_Score=73, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6319955, Length=230, Percent_Identity=28.2608695652174, Blast_Score=64, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6322619, Length=230, Percent_Identity=28.2608695652174, Blast_Score=64, Evalue=5e-11,
Organism=Drosophila melanogaster, GI45550423, Length=313, Percent_Identity=24.9201277955272, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 34426; Mature: 34294

Theoretical pI: Translated: 7.64; Mature: 7.64

Prosite motif: PS01162 QOR_ZETA_CRYSTAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKAIRYDQPGGPDVMKWVDVEVGAPKAGEVRIRQHAVGLNYIDVYFRTGLYPQQLPAGL
CCCCCCCCCCCCCCCEEEEEEECCCCCCCCEEEEEHHCCCCEEEEEHHCCCCHHHCCCCC
GMEAAGEVTAVGDGVTAFKAGDRVAYVGQPPGAYAQERVMPAERVVKLPDGISYDDAASV
CCCCCCCEEEECCCEEEEECCCEEEEECCCCCCHHHHHCCCHHHHEECCCCCCCHHHHHH
MLQGLTAHYLLRRTYPVKAGDTILIHAAAGGVGLLVCQWAKALGATVIGTVGSDEKAELA
HHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCEEEEECCCCHHHHHH
KAHGCDHPIVYTRENFTQRVKAITNGAGVPVVYDSIGKDTYVGSLDSLAPLGYFVSFGNA
HHCCCCCCEEEECHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCHHHHHHHHHHEEECCC
SGPLPPIDSKEFSSRGSLFFTRPTLFSYIAKRADLEAAAAELFDVILSGKVKTSINQRYP
CCCCCCCCCHHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCC
LAEVGRAHADLEARKTTGSTILVP
HHHHHHHHCCCHHHCCCCCEEECC
>Mature Secondary Structure 
PKAIRYDQPGGPDVMKWVDVEVGAPKAGEVRIRQHAVGLNYIDVYFRTGLYPQQLPAGL
CCCCCCCCCCCCCCEEEEEEECCCCCCCCEEEEEHHCCCCEEEEEHHCCCCHHHCCCCC
GMEAAGEVTAVGDGVTAFKAGDRVAYVGQPPGAYAQERVMPAERVVKLPDGISYDDAASV
CCCCCCCEEEECCCEEEEECCCEEEEECCCCCCHHHHHCCCHHHHEECCCCCCCHHHHHH
MLQGLTAHYLLRRTYPVKAGDTILIHAAAGGVGLLVCQWAKALGATVIGTVGSDEKAELA
HHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCEEEEECCCCHHHHHH
KAHGCDHPIVYTRENFTQRVKAITNGAGVPVVYDSIGKDTYVGSLDSLAPLGYFVSFGNA
HHCCCCCCEEEECHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCHHHHHHHHHHEEECCC
SGPLPPIDSKEFSSRGSLFFTRPTLFSYIAKRADLEAAAAELFDVILSGKVKTSINQRYP
CCCCCCCCCHHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCC
LAEVGRAHADLEARKTTGSTILVP
HHHHHHHHCCCHHHCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]