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The map label for this gene is nuoH [H]

Identifier: 116690263

GI number: 116690263

Start: 2495910

End: 2496977

Strand: Reverse

Name: nuoH [H]

Synonym: Bcen2424_2242

Alternate gene names: 116690263

Gene position: 2496977-2495910 (Counterclockwise)

Preceding gene: 116690264

Following gene: 116690262

Centisome position: 71.67

GC content: 63.86

Gene sequence:

>1068_bases
ATGAGCTTGTTCGATACGATCAACGCGGGCGGGGCCGAGCTTCTCGGCTTCGCGTGGCCGACGGTGTGGGCAGTCGTGCG
CATCCTCGTCGTCTCCGTCGTCATCCTGCTGTGCGTCGCGTACCTGATTCTGTGGGAACGCAAGCTGATCGGCTGGATGC
ACGTGCGTCTCGGCCCGAACCGCGTCGGCCCCGGCGGCCTGCTGCAGCCGATCGCCGACGTGCTGAAGCTGCTGCTGAAG
GAAGTCATTCAGCCGAGCGCCGCCAGCCGCTGGCTGTATCTGATCGCGCCGGTGATGACGGTCGTGCCGGCGTTCGCGGT
GTGGGCGGTGATTCCGTTCCAGGCGGAAGCCGTGCTCGCGAACGTGAACGCGGGCCTGCTGTACGCGATGGCGATCTCGT
CGATCGGCGTGTACGCGGTGATTCTCGCCGGCTGGGCGTCGAACTCGAAGTACGCGTTCCTCGGCGCGATGCGCGCCGCG
GCACAGATGGTGTCGTACGAAATCTCGATGGGCTTCGCGCTGGTGCTCGTGCTGATGACGGCCGGCAGCCTGAACCTGTC
GGAGATCGTCGGCTCGCAACAGCACGGCTTCTTCGCCGGCCACGGCGTGAATTTCCTGTCGTGGAACTGGCTGCCGCTGC
TGCCGGCGTTCGTCGTCTACTTCATCTCGGGCATCGCCGAAACGAACCGTCACCCGTTCGACGTGGTGGAAGGGGAGTCG
GAGATCGTCGCGGGTCACATGATCGATTACTCGGGCATGGCGTTCGCGCTGTTCTTCCTCGCCGAGTACATCAACATGAT
CGTGATCTCGGCACTGGCCGCGACGCTGTTCCTCGGCGGCTGGGACGCACCGTTCGAATTCCTGTCGTTCATCCCGGGCA
TCTTCTGGCTGGTGCTGAAGGTCTTCGCGCTGCTGTCGGTGTTCATCTGGGTGCGCGCGACGTTCCCGCGCTACCGTTAC
GACCAGATCATGCGTCTGGGCTGGAAGGTGTTCCTGCCCGTCACGGTGGTCTGGGTGATCGTGGTTGGCTTCTGGATGAT
GTCGCCGCTGAACATCTGGGTGAAGTAA

Upstream 100 bases:

>100_bases
CGCGAATCTTGCGGAGACGGTCGTTCGCGTGTCGGCGGCCACGCCTGCCGGCGCAGCGCTCGGCAGCCTGTCCGGTGAAC
TGGTGGTGGAGAAGGCGTAA

Downstream 100 bases:

>100_bases
GGACGAAATCATGACGGCTATCCAACACTTCTTTAAGACTTTCTTCCTGACCGAGCTGCTGAAGGGGCTCGCGCTGACCG
GTCGTTACACGTTCAAGCGC

Product: NADH dehydrogenase subunit H

Products: NA

Alternate protein names: NADH dehydrogenase I subunit H; NDH-1 subunit H [H]

Number of amino acids: Translated: 355; Mature: 354

Protein sequence:

>355_residues
MSLFDTINAGGAELLGFAWPTVWAVVRILVVSVVILLCVAYLILWERKLIGWMHVRLGPNRVGPGGLLQPIADVLKLLLK
EVIQPSAASRWLYLIAPVMTVVPAFAVWAVIPFQAEAVLANVNAGLLYAMAISSIGVYAVILAGWASNSKYAFLGAMRAA
AQMVSYEISMGFALVLVLMTAGSLNLSEIVGSQQHGFFAGHGVNFLSWNWLPLLPAFVVYFISGIAETNRHPFDVVEGES
EIVAGHMIDYSGMAFALFFLAEYINMIVISALAATLFLGGWDAPFEFLSFIPGIFWLVLKVFALLSVFIWVRATFPRYRY
DQIMRLGWKVFLPVTVVWVIVVGFWMMSPLNIWVK

Sequences:

>Translated_355_residues
MSLFDTINAGGAELLGFAWPTVWAVVRILVVSVVILLCVAYLILWERKLIGWMHVRLGPNRVGPGGLLQPIADVLKLLLK
EVIQPSAASRWLYLIAPVMTVVPAFAVWAVIPFQAEAVLANVNAGLLYAMAISSIGVYAVILAGWASNSKYAFLGAMRAA
AQMVSYEISMGFALVLVLMTAGSLNLSEIVGSQQHGFFAGHGVNFLSWNWLPLLPAFVVYFISGIAETNRHPFDVVEGES
EIVAGHMIDYSGMAFALFFLAEYINMIVISALAATLFLGGWDAPFEFLSFIPGIFWLVLKVFALLSVFIWVRATFPRYRY
DQIMRLGWKVFLPVTVVWVIVVGFWMMSPLNIWVK
>Mature_354_residues
SLFDTINAGGAELLGFAWPTVWAVVRILVVSVVILLCVAYLILWERKLIGWMHVRLGPNRVGPGGLLQPIADVLKLLLKE
VIQPSAASRWLYLIAPVMTVVPAFAVWAVIPFQAEAVLANVNAGLLYAMAISSIGVYAVILAGWASNSKYAFLGAMRAAA
QMVSYEISMGFALVLVLMTAGSLNLSEIVGSQQHGFFAGHGVNFLSWNWLPLLPAFVVYFISGIAETNRHPFDVVEGESE
IVAGHMIDYSGMAFALFFLAEYINMIVISALAATLFLGGWDAPFEFLSFIPGIFWLVLKVFALLSVFIWVRATFPRYRYD
QIMRLGWKVFLPVTVVWVIVVGFWMMSPLNIWVK

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1005

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 1 (chain H)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 1 family [H]

Homologues:

Organism=Homo sapiens, GI251831107, Length=302, Percent_Identity=43.046357615894, Blast_Score=255, Evalue=5e-68,
Organism=Escherichia coli, GI1788618, Length=319, Percent_Identity=40.7523510971787, Blast_Score=261, Evalue=4e-71,
Organism=Escherichia coli, GI1789077, Length=209, Percent_Identity=27.2727272727273, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023020
- InterPro:   IPR001694
- InterPro:   IPR018086 [H]

Pfam domain/function: PF00146 NADHdh [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 39260; Mature: 39129

Theoretical pI: Translated: 7.70; Mature: 7.70

Prosite motif: PS00668 COMPLEX1_ND1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLFDTINAGGAELLGFAWPTVWAVVRILVVSVVILLCVAYLILWERKLIGWMHVRLGPN
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCC
RVGPGGLLQPIADVLKLLLKEVIQPSAASRWLYLIAPVMTVVPAFAVWAVIPFQAEAVLA
CCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
NVNAGLLYAMAISSIGVYAVILAGWASNSKYAFLGAMRAAAQMVSYEISMGFALVLVLMT
HCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGSLNLSEIVGSQQHGFFAGHGVNFLSWNWLPLLPAFVVYFISGIAETNRHPFDVVEGES
CCCCCHHHHHCCCCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEECCCC
EIVAGHMIDYSGMAFALFFLAEYINMIVISALAATLFLGGWDAPFEFLSFIPGIFWLVLK
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
VFALLSVFIWVRATFPRYRYDQIMRLGWKVFLPVTVVWVIVVGFWMMSPLNIWVK
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCC
>Mature Secondary Structure 
SLFDTINAGGAELLGFAWPTVWAVVRILVVSVVILLCVAYLILWERKLIGWMHVRLGPN
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCC
RVGPGGLLQPIADVLKLLLKEVIQPSAASRWLYLIAPVMTVVPAFAVWAVIPFQAEAVLA
CCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
NVNAGLLYAMAISSIGVYAVILAGWASNSKYAFLGAMRAAAQMVSYEISMGFALVLVLMT
HCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGSLNLSEIVGSQQHGFFAGHGVNFLSWNWLPLLPAFVVYFISGIAETNRHPFDVVEGES
CCCCCHHHHHCCCCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEECCCC
EIVAGHMIDYSGMAFALFFLAEYINMIVISALAATLFLGGWDAPFEFLSFIPGIFWLVLK
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
VFALLSVFIWVRATFPRYRYDQIMRLGWKVFLPVTVVWVIVVGFWMMSPLNIWVK
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA