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The map label for this gene is nuoI [H]

Identifier: 116690262

GI number: 116690262

Start: 2495411

End: 2495899

Strand: Reverse

Name: nuoI [H]

Synonym: Bcen2424_2241

Alternate gene names: 116690262

Gene position: 2495899-2495411 (Counterclockwise)

Preceding gene: 116690263

Following gene: 116690261

Centisome position: 71.64

GC content: 61.35

Gene sequence:

>489_bases
ATGACGGCTATCCAACACTTCTTTAAGACTTTCTTCCTGACCGAGCTGCTGAAGGGGCTCGCGCTGACCGGTCGTTACAC
GTTCAAGCGCAAGTTCACCGTGCAGTTCCCGGAAGAGAAGACCCCGATTTCGCCGCGTTTCCGCGGGCTGCACGCGCTGC
GCCGCTACGAAAACGGCGAAGAGCGCTGCATCGCGTGCAAGCTGTGCGAGGCCGTGTGCCCCGCACTGGCGATCACGATC
GAATCGGAAACGCGCGCGGACAACACGCGCCGCACGACGCGCTACGACATCGACCTGACGAAGTGCATCTTCTGCGGTTT
CTGCGAAGAGAGCTGCCCGGTCGATTCGATCGTCGAGACGCAGATTCTCGAGTACCACGGCGAAAAGCGCGGCGACCTGT
ATTTCACGAAGGAAATGCTGCTCGCGGTGGGCGATCGCTACGAGAAGGACATCGCCGCGGCGAAGGCTGCCGACGCGCCG
TATCGTTGA

Upstream 100 bases:

>100_bases
GGCTGGAAGGTGTTCCTGCCCGTCACGGTGGTCTGGGTGATCGTGGTTGGCTTCTGGATGATGTCGCCGCTGAACATCTG
GGTGAAGTAAGGACGAAATC

Downstream 100 bases:

>100_bases
TTGTGTTTGCAGTGCCGGCCCGGCATGAACGATGCACGGGCCGAGCCGCCGCGACGGGTGCGGGCGTTCCGCAAGCCGCG
CCTGACTATGGCCTAACGAT

Product: NADH dehydrogenase subunit I

Products: NA

Alternate protein names: NADH dehydrogenase I subunit I; NDH-1 subunit I [H]

Number of amino acids: Translated: 162; Mature: 161

Protein sequence:

>162_residues
MTAIQHFFKTFFLTELLKGLALTGRYTFKRKFTVQFPEEKTPISPRFRGLHALRRYENGEERCIACKLCEAVCPALAITI
ESETRADNTRRTTRYDIDLTKCIFCGFCEESCPVDSIVETQILEYHGEKRGDLYFTKEMLLAVGDRYEKDIAAAKAADAP
YR

Sequences:

>Translated_162_residues
MTAIQHFFKTFFLTELLKGLALTGRYTFKRKFTVQFPEEKTPISPRFRGLHALRRYENGEERCIACKLCEAVCPALAITI
ESETRADNTRRTTRYDIDLTKCIFCGFCEESCPVDSIVETQILEYHGEKRGDLYFTKEMLLAVGDRYEKDIAAAKAADAP
YR
>Mature_161_residues
TAIQHFFKTFFLTELLKGLALTGRYTFKRKFTVQFPEEKTPISPRFRGLHALRRYENGEERCIACKLCEAVCPALAITIE
SETRADNTRRTTRYDIDLTKCIFCGFCEESCPVDSIVETQILEYHGEKRGDLYFTKEMLLAVGDRYEKDIAAAKAADAPY
R

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1143

COG function: function code C; Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Homo sapiens, GI4505371, Length=154, Percent_Identity=60.3896103896104, Blast_Score=198, Evalue=2e-51,
Organism=Escherichia coli, GI1788617, Length=139, Percent_Identity=38.1294964028777, Blast_Score=99, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17555194, Length=159, Percent_Identity=54.7169811320755, Blast_Score=186, Evalue=4e-48,
Organism=Drosophila melanogaster, GI17864306, Length=154, Percent_Identity=60.3896103896104, Blast_Score=197, Evalue=4e-51,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001450
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012285
- InterPro:   IPR010226 [H]

Pfam domain/function: PF00037 Fer4 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 18656; Mature: 18524

Theoretical pI: Translated: 7.68; Mature: 7.68

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
5.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAIQHFFKTFFLTELLKGLALTGRYTFKRKFTVQFPEEKTPISPRFRGLHALRRYENGE
CHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCC
ERCIACKLCEAVCPALAITIESETRADNTRRTTRYDIDLTKCIFCGFCEESCPVDSIVET
HHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCEEECCHHHHHHHHHCCCCCCCHHHHHHH
QILEYHGEKRGDLYFTKEMLLAVGDRYEKDIAAAKAADAPYR
HHHHHCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TAIQHFFKTFFLTELLKGLALTGRYTFKRKFTVQFPEEKTPISPRFRGLHALRRYENGE
HHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCC
ERCIACKLCEAVCPALAITIESETRADNTRRTTRYDIDLTKCIFCGFCEESCPVDSIVET
HHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCEEECCHHHHHHHHHCCCCCCCHHHHHHH
QILEYHGEKRGDLYFTKEMLLAVGDRYEKDIAAAKAADAPYR
HHHHHCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA