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The map label for this gene is acdA [H]

Identifier: 116690253

GI number: 116690253

Start: 2486516

End: 2487712

Strand: Reverse

Name: acdA [H]

Synonym: Bcen2424_2232

Alternate gene names: 116690253

Gene position: 2487712-2486516 (Counterclockwise)

Preceding gene: 116690254

Following gene: 116690252

Centisome position: 71.41

GC content: 66.08

Gene sequence:

>1197_bases
ATGGATCTGGATTATTCCCCCGCCGACGACGCGTTCCGCGTTGACGTCCGCGCCTGGCTCGAGGCCAACCTGCCTCACGC
ACTGCGCGCCAAGGTACTCGATCACAAACGACTCGACCGCGAGGATTTCGCGAGCTGGCACCGGATTCTGGGCCAGCGCG
GCTGGTCCGCACCCGCGTGGCCGGTCGAATATGGCGGCCCGGGCTGGAACGCGACGCAGCGGCACATCTGGGACGAGGAG
TGCGCGCGGATCGGTGCGCCGACCGTGCTGCCGTTCGGGGTGTCGATGGTCGCGCCGGTCCTGATGAAATACGGCAGCGA
TGCGCAGAAGCGCCACTATCTGCCGCGTATTCTCGACGGCTCGGACTGGTGGTGCCAGGGTTATTCGGAGCCGGGTTCCG
GGTCCGACCTCGCGTCGCTGCGCACGCGCGCCGAGCGCCACGGCGATCACTACGTCGTCAACGGCCAGAAGACCTGGACC
ACGCTCGGCCAGTACGCCGACATGATGTTCTGCCTCGTGCGCACCGATCCGGCCGCGAAGAAGCAGGAGGGCATCTCGTT
CCTGCTGATCGACATGAAGACGCCCGGCATCACGGTGCGGCCGATCGTGATGCTCGACGAGGACCACGAGGTCAACGAGG
TGTTCTTCGAGGACGTGAAGGTGCCGGTCGAGAATCTCGTCGGCGACGAGAACCGCGGCTGGACCTACGCGAAATACCTG
CTCGGCCACGAGCGCACCGGCATCGCGCGCGTCGGCGCGTCGAAGCGGGAGCTTGCGTTCCTGAAGCGCGTCGCATCGAA
TCAGCGCAAGAACGGCAAGCCGTTGCTCGCCGATCCCGTGTTCGCCGCGAAGGTCGCGGCACTCGAAGTCGAGTTGATGG
CGCTGGAAGTGACGGTGCTGCGCGTCGTCAGCCGCGAGACGAGCGGCAAGGGGCCCGGCCCCGAGGCGTCGATGCTGAAG
ATCAAGGGCACCGAGGTGCAGCAGGCGCTCACCGAGCTGATGGTCGAAGCGATCGGCCCGCTGGCCGCCCCATTCGACGT
GCCGTTTCTCGACGGCGAGCGCGAGCACAGCATCGCGGGCGACGACGATGCGGCGCCGCTCGCCGCGTACTACTTCAATT
ACCGGAAGACGTCGATCTACGGCGGTTCGAACGAGATCCAGAAGAACATCATCGCGCAGATGATTCTGGGGCTGTGA

Upstream 100 bases:

>100_bases
GATGCCGCTGCCGATTCCAGCCGCGCTGAAAGAACCGCTGCAATGACGTACGCAGTGTGTCCTGGCCGGCCCGGACGGTC
GCGGACAGGAGACACTGCGC

Downstream 100 bases:

>100_bases
TCAGGGAACGGAGACAACCATGGATTTCAGCTTTACCGATGAGCAGCAGCAGTTCGCCGACGCGCTGCGCCGGTATCTCG
GCGAGCAATATGGCTTCGAA

Product: acyl-CoA dehydrogenase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 398; Mature: 398

Protein sequence:

>398_residues
MDLDYSPADDAFRVDVRAWLEANLPHALRAKVLDHKRLDREDFASWHRILGQRGWSAPAWPVEYGGPGWNATQRHIWDEE
CARIGAPTVLPFGVSMVAPVLMKYGSDAQKRHYLPRILDGSDWWCQGYSEPGSGSDLASLRTRAERHGDHYVVNGQKTWT
TLGQYADMMFCLVRTDPAAKKQEGISFLLIDMKTPGITVRPIVMLDEDHEVNEVFFEDVKVPVENLVGDENRGWTYAKYL
LGHERTGIARVGASKRELAFLKRVASNQRKNGKPLLADPVFAAKVAALEVELMALEVTVLRVVSRETSGKGPGPEASMLK
IKGTEVQQALTELMVEAIGPLAAPFDVPFLDGEREHSIAGDDDAAPLAAYYFNYRKTSIYGGSNEIQKNIIAQMILGL

Sequences:

>Translated_398_residues
MDLDYSPADDAFRVDVRAWLEANLPHALRAKVLDHKRLDREDFASWHRILGQRGWSAPAWPVEYGGPGWNATQRHIWDEE
CARIGAPTVLPFGVSMVAPVLMKYGSDAQKRHYLPRILDGSDWWCQGYSEPGSGSDLASLRTRAERHGDHYVVNGQKTWT
TLGQYADMMFCLVRTDPAAKKQEGISFLLIDMKTPGITVRPIVMLDEDHEVNEVFFEDVKVPVENLVGDENRGWTYAKYL
LGHERTGIARVGASKRELAFLKRVASNQRKNGKPLLADPVFAAKVAALEVELMALEVTVLRVVSRETSGKGPGPEASMLK
IKGTEVQQALTELMVEAIGPLAAPFDVPFLDGEREHSIAGDDDAAPLAAYYFNYRKTSIYGGSNEIQKNIIAQMILGL
>Mature_398_residues
MDLDYSPADDAFRVDVRAWLEANLPHALRAKVLDHKRLDREDFASWHRILGQRGWSAPAWPVEYGGPGWNATQRHIWDEE
CARIGAPTVLPFGVSMVAPVLMKYGSDAQKRHYLPRILDGSDWWCQGYSEPGSGSDLASLRTRAERHGDHYVVNGQKTWT
TLGQYADMMFCLVRTDPAAKKQEGISFLLIDMKTPGITVRPIVMLDEDHEVNEVFFEDVKVPVENLVGDENRGWTYAKYL
LGHERTGIARVGASKRELAFLKRVASNQRKNGKPLLADPVFAAKVAALEVELMALEVTVLRVVSRETSGKGPGPEASMLK
IKGTEVQQALTELMVEAIGPLAAPFDVPFLDGEREHSIAGDDDAAPLAAYYFNYRKTSIYGGSNEIQKNIIAQMILGL

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=368, Percent_Identity=27.7173913043478, Blast_Score=122, Evalue=7e-28,
Organism=Homo sapiens, GI4501857, Length=402, Percent_Identity=26.1194029850746, Blast_Score=119, Evalue=3e-27,
Organism=Homo sapiens, GI226958414, Length=201, Percent_Identity=33.3333333333333, Blast_Score=115, Evalue=5e-26,
Organism=Homo sapiens, GI4501859, Length=353, Percent_Identity=27.4787535410765, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI226958412, Length=244, Percent_Identity=30.327868852459, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI4557231, Length=341, Percent_Identity=26.6862170087977, Blast_Score=108, Evalue=8e-24,
Organism=Homo sapiens, GI187960098, Length=341, Percent_Identity=26.6862170087977, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI211971008, Length=351, Percent_Identity=26.7806267806268, Blast_Score=105, Evalue=9e-23,
Organism=Homo sapiens, GI48976061, Length=351, Percent_Identity=26.7806267806268, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI21361497, Length=336, Percent_Identity=27.0833333333333, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI7656849, Length=355, Percent_Identity=24.2253521126761, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI4557235, Length=294, Percent_Identity=28.9115646258503, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI76496475, Length=294, Percent_Identity=28.9115646258503, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI38505218, Length=310, Percent_Identity=26.4516129032258, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI4503943, Length=292, Percent_Identity=26.3698630136986, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI7669494, Length=292, Percent_Identity=26.3698630136986, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI87081958, Length=407, Percent_Identity=22.8501228501229, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1786223, Length=401, Percent_Identity=21.9451371571072, Blast_Score=82, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17538396, Length=206, Percent_Identity=32.0388349514563, Blast_Score=111, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI17508101, Length=355, Percent_Identity=26.1971830985915, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17551932, Length=212, Percent_Identity=32.0754716981132, Blast_Score=106, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17569725, Length=356, Percent_Identity=26.4044943820225, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17506239, Length=351, Percent_Identity=25.9259259259259, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI71985184, Length=210, Percent_Identity=34.7619047619048, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17570075, Length=352, Percent_Identity=24.4318181818182, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI71985192, Length=210, Percent_Identity=34.7619047619048, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17534899, Length=343, Percent_Identity=24.7813411078717, Blast_Score=99, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI32563615, Length=198, Percent_Identity=31.3131313131313, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17505929, Length=351, Percent_Identity=25.3561253561254, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI71990804, Length=206, Percent_Identity=27.6699029126214, Blast_Score=88, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17533517, Length=257, Percent_Identity=28.0155642023346, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71982178, Length=195, Percent_Identity=26.6666666666667, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17534353, Length=265, Percent_Identity=24.9056603773585, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17562446, Length=350, Percent_Identity=23.4285714285714, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21356377, Length=368, Percent_Identity=27.1739130434783, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI281363737, Length=303, Percent_Identity=28.3828382838284, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI21355753, Length=212, Percent_Identity=33.0188679245283, Blast_Score=105, Evalue=6e-23,
Organism=Drosophila melanogaster, GI24666513, Length=343, Percent_Identity=26.2390670553936, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24646207, Length=365, Percent_Identity=26.8493150684932, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24660351, Length=214, Percent_Identity=31.7757009345794, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI19920834, Length=401, Percent_Identity=24.1895261845387, Blast_Score=78, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 44292; Mature: 44292

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLDYSPADDAFRVDVRAWLEANLPHALRAKVLDHKRLDREDFASWHRILGQRGWSAPAW
CCCCCCCCCCCEEEHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCC
PVEYGGPGWNATQRHIWDEECARIGAPTVLPFGVSMVAPVLMKYGSDAQKRHYLPRILDG
CCCCCCCCCCCHHHHCCHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHCCCCEEECC
SDWWCQGYSEPGSGSDLASLRTRAERHGDHYVVNGQKTWTTLGQYADMMFCLVRTDPAAK
CCCEECCCCCCCCCCHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHEEEEECCCCHH
KQEGISFLLIDMKTPGITVRPIVMLDEDHEVNEVFFEDVKVPVENLVGDENRGWTYAKYL
HHCCCEEEEEEECCCCEEEEEEEEECCCCCHHHHHHHHHCCCHHHHCCCCCCCCCHHHHH
LGHERTGIARVGASKRELAFLKRVASNQRKNGKPLLADPVFAAKVAALEVELMALEVTVL
HCCCCCCHHHCCCCHHHHHHHHHHHHCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHH
RVVSRETSGKGPGPEASMLKIKGTEVQQALTELMVEAIGPLAAPFDVPFLDGEREHSIAG
HHHHHHCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
DDDAAPLAAYYFNYRKTSIYGGSNEIQKNIIAQMILGL
CCCCCHHHHHHHHCEEEEEECCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDLDYSPADDAFRVDVRAWLEANLPHALRAKVLDHKRLDREDFASWHRILGQRGWSAPAW
CCCCCCCCCCCEEEHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCC
PVEYGGPGWNATQRHIWDEECARIGAPTVLPFGVSMVAPVLMKYGSDAQKRHYLPRILDG
CCCCCCCCCCCHHHHCCHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHCCCCEEECC
SDWWCQGYSEPGSGSDLASLRTRAERHGDHYVVNGQKTWTTLGQYADMMFCLVRTDPAAK
CCCEECCCCCCCCCCHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHEEEEECCCCHH
KQEGISFLLIDMKTPGITVRPIVMLDEDHEVNEVFFEDVKVPVENLVGDENRGWTYAKYL
HHCCCEEEEEEECCCCEEEEEEEEECCCCCHHHHHHHHHCCCHHHHCCCCCCCCCHHHHH
LGHERTGIARVGASKRELAFLKRVASNQRKNGKPLLADPVFAAKVAALEVELMALEVTVL
HCCCCCCHHHCCCCHHHHHHHHHHHHCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHH
RVVSRETSGKGPGPEASMLKIKGTEVQQALTELMVEAIGPLAAPFDVPFLDGEREHSIAG
HHHHHHCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
DDDAAPLAAYYFNYRKTSIYGGSNEIQKNIIAQMILGL
CCCCCHHHHHHHHCEEEEEECCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]