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The map label for this gene is wzb [C]

Identifier: 116690149

GI number: 116690149

Start: 2360238

End: 2360720

Strand: Reverse

Name: wzb [C]

Synonym: Bcen2424_2128

Alternate gene names: 116690149

Gene position: 2360720-2360238 (Counterclockwise)

Preceding gene: 116690150

Following gene: 116690148

Centisome position: 67.76

GC content: 70.19

Gene sequence:

>483_bases
ATGACCCGCGTTGCGATCTGTTTCGTCTGTCTCGGCAACATCTGCCGTTCGCCCACCGCGGAAGGCGTGATGCGCCACCA
GGTCGACGCGGCCGCGCTGGCCGACCGGATCGCGATCGATTCGGCCGGCACCGGCGACTGGCACGTGGGCGAGCCGCCCG
ATACGCGGGCGCAGGCGGCGGCCCGCAGCCGCGGCTACGATCTGTCGGCGCTGCGCGCCCGGCAGGTGAGCGCGGCGGAT
TTCGAACAATTCGACCTGCTGCTCGCGATGGACGAGGCGAATCTCGCCGAACTGCGCCGCCGTTGCCCGCCGCAGCACCG
CGAGAAAGTGCGCCTGTTGATGGAATTCGCGCCGGGCGCGACCGAAACCGAAGTGGCCGATCCGTATTTCGGCGGCGCGC
AAGGCTTCGAGCAGGTGCTCGACCAGGTCGAGCGCGCATGCGCGGGTCTGCTGGAGACGCTGCGCGCACGCACGGCGCAC
TGA

Upstream 100 bases:

>100_bases
GCATGGCGCCGTCGCTTTGCGCGGCGGCGCGATTTCGGCCGCCTTTGTATAATGGCGTGTTCTTCTCCCACGCGGTCCGC
CGCGGCTTTTCGATAGTGCG

Downstream 100 bases:

>100_bases
CCGCACGCTATTCAGCGGCCTGCGAATACCCTTTCAAAGACATGGATACTTGACTAAAAACGTCAAATATTTATACTTGA
CCAAAATCGTCAAGATTGCA

Product: protein tyrosine phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 160; Mature: 159

Protein sequence:

>160_residues
MTRVAICFVCLGNICRSPTAEGVMRHQVDAAALADRIAIDSAGTGDWHVGEPPDTRAQAAARSRGYDLSALRARQVSAAD
FEQFDLLLAMDEANLAELRRRCPPQHREKVRLLMEFAPGATETEVADPYFGGAQGFEQVLDQVERACAGLLETLRARTAH

Sequences:

>Translated_160_residues
MTRVAICFVCLGNICRSPTAEGVMRHQVDAAALADRIAIDSAGTGDWHVGEPPDTRAQAAARSRGYDLSALRARQVSAAD
FEQFDLLLAMDEANLAELRRRCPPQHREKVRLLMEFAPGATETEVADPYFGGAQGFEQVLDQVERACAGLLETLRARTAH
>Mature_159_residues
TRVAICFVCLGNICRSPTAEGVMRHQVDAAALADRIAIDSAGTGDWHVGEPPDTRAQAAARSRGYDLSALRARQVSAADF
EQFDLLLAMDEANLAELRRRCPPQHREKVRLLMEFAPGATETEVADPYFGGAQGFEQVLDQVERACAGLLETLRARTAH

Specific function: Dephosphorylates Wzc. Required For The Extracellular Polysaccharide Colanic Acid Synthesis. Probably Involved In The Export Of Colanic Acid From The Cell To Medium. [C]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase family [H]

Homologues:

Organism=Homo sapiens, GI6005988, Length=150, Percent_Identity=40.6666666666667, Blast_Score=118, Evalue=2e-27,
Organism=Homo sapiens, GI4757714, Length=150, Percent_Identity=39.3333333333333, Blast_Score=116, Evalue=9e-27,
Organism=Homo sapiens, GI96304457, Length=78, Percent_Identity=42.3076923076923, Blast_Score=70, Evalue=8e-13,
Organism=Escherichia coli, GI87081812, Length=142, Percent_Identity=31.6901408450704, Blast_Score=62, Evalue=1e-11,
Organism=Escherichia coli, GI1788375, Length=143, Percent_Identity=33.5664335664336, Blast_Score=62, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6325330, Length=153, Percent_Identity=33.3333333333333, Blast_Score=118, Evalue=4e-28,
Organism=Drosophila melanogaster, GI78706766, Length=148, Percent_Identity=37.8378378378378, Blast_Score=109, Evalue=7e-25,
Organism=Drosophila melanogaster, GI78706768, Length=148, Percent_Identity=37.8378378378378, Blast_Score=109, Evalue=7e-25,
Organism=Drosophila melanogaster, GI78706770, Length=156, Percent_Identity=37.1794871794872, Blast_Score=105, Evalue=1e-23,
Organism=Drosophila melanogaster, GI78706772, Length=156, Percent_Identity=37.1794871794872, Blast_Score=105, Evalue=1e-23,
Organism=Drosophila melanogaster, GI78706764, Length=125, Percent_Identity=37.6, Blast_Score=98, Evalue=2e-21,
Organism=Drosophila melanogaster, GI78711846, Length=157, Percent_Identity=35.031847133758, Blast_Score=97, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000106
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 17467; Mature: 17336

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRVAICFVCLGNICRSPTAEGVMRHQVDAAALADRIAIDSAGTGDWHVGEPPDTRAQAA
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHH
ARSRGYDLSALRARQVSAADFEQFDLLLAMDEANLAELRRRCPPQHREKVRLLMEFAPGA
HHHCCCCHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHCCHHHHHHHHHHHHHCCCC
TETEVADPYFGGAQGFEQVLDQVERACAGLLETLRARTAH
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TRVAICFVCLGNICRSPTAEGVMRHQVDAAALADRIAIDSAGTGDWHVGEPPDTRAQAA
CHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHH
ARSRGYDLSALRARQVSAADFEQFDLLLAMDEANLAELRRRCPPQHREKVRLLMEFAPGA
HHHCCCCHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHCCHHHHHHHHHHHHHCCCC
TETEVADPYFGGAQGFEQVLDQVERACAGLLETLRARTAH
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]