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The map label for this gene is hscB [H]

Identifier: 116690144

GI number: 116690144

Start: 2356807

End: 2357412

Strand: Reverse

Name: hscB [H]

Synonym: Bcen2424_2123

Alternate gene names: 116690144

Gene position: 2357412-2356807 (Counterclockwise)

Preceding gene: 116690145

Following gene: 116690143

Centisome position: 67.67

GC content: 66.5

Gene sequence:

>606_bases
ATGCGGGTAAGAGGCGGCACGGGCCGCCTTTTTAATGTGCGGCGTTTGCCGCACGACGAACCGGAATTGAACGCGACGAT
GGTTTCGCTGAAAGACAGCCATTTCGACCTGTTTCACCTACCGGCGCAATTCGCGCTCGACGAGGCGGCGCTCGACGCCG
CCTACCGGACGGTGCAGACGCAGGTGCATCCCGACCGCTTCGCGGCGGCCGGCGATGCGCAAAAGCGTATCGCGATGCAA
TGGGCCACTCGCGCGAACGAGGCGTACCGCACGCTGCGCGATCCGTTGAAGCGCGCGTCCTATCTGCTGTCGCTGCGCGG
TGTCGACATCGGCGCGGAAAACAACACGGCGATGGAGCCTGCGTTCCTGATGCAGCAGATGGAGTGGCGCGAGGGCATCG
AGGATGCCGCGGCCGCCCGCAACGTCGACGCGCTCGATGCGCTGCTCGCCGAGCTGCGCGACGAGAAGCGCGTGCGCGTC
GAGCGCCTCGGCACGCTGCTCGACAGCGGTGCCGACCAGGCCGCCGCGGAAGCCGTGCGTCAGCTGATGTTCATCGAACG
GGTCGCGTCGGAAGTGGGCGCGCAGATCGAGCGCCTCGAAACTTAA

Upstream 100 bases:

>100_bases
CGAAGGCCTGAACGAAGGGTTCAAGTTCAACAACCCGAACGTGAAGGACGAGTGCGGGTGCGGGGAATCGTTCCGCGTGT
GACGCGGCTCCCTCCGCGCG

Downstream 100 bases:

>100_bases
CCGCGTGCCTTGCGGCACGCGCAGCAAACGGGCCGAGCGCCCGAACGAACCAAGATGGCTTTACTGCAAATTTCCGAACC
GGGCATGGCGCCGGCGCCGC

Product: co-chaperone HscB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 201; Mature: 201

Protein sequence:

>201_residues
MRVRGGTGRLFNVRRLPHDEPELNATMVSLKDSHFDLFHLPAQFALDEAALDAAYRTVQTQVHPDRFAAAGDAQKRIAMQ
WATRANEAYRTLRDPLKRASYLLSLRGVDIGAENNTAMEPAFLMQQMEWREGIEDAAAARNVDALDALLAELRDEKRVRV
ERLGTLLDSGADQAAAEAVRQLMFIERVASEVGAQIERLET

Sequences:

>Translated_201_residues
MRVRGGTGRLFNVRRLPHDEPELNATMVSLKDSHFDLFHLPAQFALDEAALDAAYRTVQTQVHPDRFAAAGDAQKRIAMQ
WATRANEAYRTLRDPLKRASYLLSLRGVDIGAENNTAMEPAFLMQQMEWREGIEDAAAARNVDALDALLAELRDEKRVRV
ERLGTLLDSGADQAAAEAVRQLMFIERVASEVGAQIERLET
>Mature_201_residues
MRVRGGTGRLFNVRRLPHDEPELNATMVSLKDSHFDLFHLPAQFALDEAALDAAYRTVQTQVHPDRFAAAGDAQKRIAMQ
WATRANEAYRTLRDPLKRASYLLSLRGVDIGAENNTAMEPAFLMQQMEWREGIEDAAAARNVDALDALLAELRDEKRVRV
ERLGTLLDSGADQAAAEAVRQLMFIERVASEVGAQIERLET

Specific function: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward hscA [H]

COG id: COG1076

COG function: function code O; DnaJ-domain-containing proteins 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 J domain [H]

Homologues:

Organism=Homo sapiens, GI50301234, Length=164, Percent_Identity=26.8292682926829, Blast_Score=68, Evalue=5e-12,
Organism=Escherichia coli, GI1788876, Length=166, Percent_Identity=36.7469879518072, Blast_Score=112, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17541320, Length=145, Percent_Identity=26.8965517241379, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI161084223, Length=168, Percent_Identity=29.1666666666667, Blast_Score=91, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001623
- InterPro:   IPR009073
- InterPro:   IPR004640 [H]

Pfam domain/function: PF00226 DnaJ; PF07743 HSCB_C [H]

EC number: NA

Molecular weight: Translated: 22503; Mature: 22503

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: PS50076 DNAJ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVRGGTGRLFNVRRLPHDEPELNATMVSLKDSHFDLFHLPAQFALDEAALDAAYRTVQT
CCCCCCCCCEEEECCCCCCCCCCCCEEEEECCCCCHHHHCCHHHHHHHHHHHHHHHHHHH
QVHPDRFAAAGDAQKRIAMQWATRANEAYRTLRDPLKRASYLLSLRGVDIGAENNTAMEP
HCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCCCCCH
AFLMQQMEWREGIEDAAAARNVDALDALLAELRDEKRVRVERLGTLLDSGADQAAAEAVR
HHHHHHHHHHHCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
QLMFIERVASEVGAQIERLET
HHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRVRGGTGRLFNVRRLPHDEPELNATMVSLKDSHFDLFHLPAQFALDEAALDAAYRTVQT
CCCCCCCCCEEEECCCCCCCCCCCCEEEEECCCCCHHHHCCHHHHHHHHHHHHHHHHHHH
QVHPDRFAAAGDAQKRIAMQWATRANEAYRTLRDPLKRASYLLSLRGVDIGAENNTAMEP
HCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCCCCCH
AFLMQQMEWREGIEDAAAARNVDALDALLAELRDEKRVRVERLGTLLDSGADQAAAEAVR
HHHHHHHHHHHCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
QLMFIERVASEVGAQIERLET
HHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA