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The map label for this gene is cysS [H]

Identifier: 116690099

GI number: 116690099

Start: 2308282

End: 2309679

Strand: Reverse

Name: cysS [H]

Synonym: Bcen2424_2078

Alternate gene names: 116690099

Gene position: 2309679-2308282 (Counterclockwise)

Preceding gene: 116690104

Following gene: 116690098

Centisome position: 66.3

GC content: 65.45

Gene sequence:

>1398_bases
ATGGAATCACTGCGCATCTACAACACGCTCGCGCGTGACAAGCAAGTTTTCGTGCCGCGCCAGCCCGGCGAGGTGCGGAT
GTACGTATGCGGGATCACCGTCTACGACTATTGTCACGTGGGCCACGCGCGCATGCTGGTCGTGTTCGACCTCGTCCAGC
GCTGGCTGCGTGCGATCGGCTATCGGGTCACGTACGTGCGCAACATCACCGACATCGACGACAAGATCATCCGCCGCGCG
GTCGAGAACGGCGAGACGATCAAGTCGCTGACCGACCGCTTCATCGGCGCGATGCACGAGGATGAAACCGCGCTCGGCAT
CCAGCGGCCCGACGTCGAGCCGCGCGCGACGCAGTTCATCCCGCAGATGCTCGGCATGATCGAGACGCTCGAGACGAACG
GCTACGCGTATCAGGCGGCCGACGGCGACGTCAATTACTCGGTGCGCAAGTTCGCAGACTACGGGAAGCTGTCGGGCAAG
TCGCTCGACGATCTCCGCGCGGGCGAGCGCGTCGCCGCGAACGATGCGAAGCAGGATCCGCTCGACTTCGTGCTGTGGAA
GCGCGCGAAGGCGGACGAGCCGGAAGGCGCGTCGTGGGCGTCGAAGTACGGGATGGGCCGCCCGGGCTGGCACATCGAGT
GCTCGGCGATGGGCTGCTCGCTGCTCGGCAATCATTTCGACATCCACGGCGGCGGGCAGGACCTGCAATTCCCGCACCAC
GAGAACGAGATCGCGCAGAGCGAAGGCGCGACCGGCGAGACGTTCGTCAACTACTGGATGCACAACGGCTTCGTGCAGGT
CGACAACGAGAAGATGTCGAAATCGCTCGGCAACTTCTTCACGATCCGCGAGGTGCTCGAGCGTTACGACGCGGAAGTCG
TGCGCTTCTTCATCGTGCGCACGCACTACCGTTCGCCGCTCAATTACAGCGACGTGCATCTCGACGATGCGCGCGCGTCG
CTCACGCGTCTGTACACCGCGCTGAAGGACGTCGAGCCCGACACGCTCGCGCTCGACTGGAACGAGCCGCACGCGCAACG
TTTCGCGGCGGCGATGAACGACGATTTCAACACGCCGGTCGCGGTGGCGACGCTGTTCGAGCTGGCGGGTGAAGTCAACC
GCACGCGCGATGCCTCGCTCGCACGGCAACTGAAACAGCTGGCGGGCCTGCTCGGCCTGCTGGGCCGCGAACCGCGCGCG
TTCCTGCAGCAGGCGTCCGGTGCCGCTCAGGCGGGCGGGCTCGCGGCCGACGAGATCGAAGCGCAGATCGCCGCGCGCGT
CGCGGCGAAGCAAGCGAAGGACTATGCCGAAGCGGACCGGATCCGGGCGGAATTGCTCGAAGCCGGCATCGCACTTGAAG
ACAAACCGGGCGGATCGACCGAATGGCGTCGCGTATGA

Upstream 100 bases:

>100_bases
TCGAGGACGCGCGGCCTGGCGCCGCAGCAGATGGTCCGTCCGTTTCACATGCTGGGCGAGCTTCGCCAGGGCGGTTTCCT
TCGGCTCACGGTTCATCTCT

Downstream 100 bases:

>100_bases
GCGCAGCGCGTTCCACTGACCGATCCGTCAGGTAGGAGGCAAGATGGCAACGGCCAGAAAAGCGCCGGTCAGGCGCGCGA
CCCCGGTCGCCGCGCGTCCG

Product: cysteinyl-tRNA synthetase

Products: NA

Alternate protein names: Cysteine--tRNA ligase 2; CysRS 2 [H]

Number of amino acids: Translated: 465; Mature: 465

Protein sequence:

>465_residues
MESLRIYNTLARDKQVFVPRQPGEVRMYVCGITVYDYCHVGHARMLVVFDLVQRWLRAIGYRVTYVRNITDIDDKIIRRA
VENGETIKSLTDRFIGAMHEDETALGIQRPDVEPRATQFIPQMLGMIETLETNGYAYQAADGDVNYSVRKFADYGKLSGK
SLDDLRAGERVAANDAKQDPLDFVLWKRAKADEPEGASWASKYGMGRPGWHIECSAMGCSLLGNHFDIHGGGQDLQFPHH
ENEIAQSEGATGETFVNYWMHNGFVQVDNEKMSKSLGNFFTIREVLERYDAEVVRFFIVRTHYRSPLNYSDVHLDDARAS
LTRLYTALKDVEPDTLALDWNEPHAQRFAAAMNDDFNTPVAVATLFELAGEVNRTRDASLARQLKQLAGLLGLLGREPRA
FLQQASGAAQAGGLAADEIEAQIAARVAAKQAKDYAEADRIRAELLEAGIALEDKPGGSTEWRRV

Sequences:

>Translated_465_residues
MESLRIYNTLARDKQVFVPRQPGEVRMYVCGITVYDYCHVGHARMLVVFDLVQRWLRAIGYRVTYVRNITDIDDKIIRRA
VENGETIKSLTDRFIGAMHEDETALGIQRPDVEPRATQFIPQMLGMIETLETNGYAYQAADGDVNYSVRKFADYGKLSGK
SLDDLRAGERVAANDAKQDPLDFVLWKRAKADEPEGASWASKYGMGRPGWHIECSAMGCSLLGNHFDIHGGGQDLQFPHH
ENEIAQSEGATGETFVNYWMHNGFVQVDNEKMSKSLGNFFTIREVLERYDAEVVRFFIVRTHYRSPLNYSDVHLDDARAS
LTRLYTALKDVEPDTLALDWNEPHAQRFAAAMNDDFNTPVAVATLFELAGEVNRTRDASLARQLKQLAGLLGLLGREPRA
FLQQASGAAQAGGLAADEIEAQIAARVAAKQAKDYAEADRIRAELLEAGIALEDKPGGSTEWRRV
>Mature_465_residues
MESLRIYNTLARDKQVFVPRQPGEVRMYVCGITVYDYCHVGHARMLVVFDLVQRWLRAIGYRVTYVRNITDIDDKIIRRA
VENGETIKSLTDRFIGAMHEDETALGIQRPDVEPRATQFIPQMLGMIETLETNGYAYQAADGDVNYSVRKFADYGKLSGK
SLDDLRAGERVAANDAKQDPLDFVLWKRAKADEPEGASWASKYGMGRPGWHIECSAMGCSLLGNHFDIHGGGQDLQFPHH
ENEIAQSEGATGETFVNYWMHNGFVQVDNEKMSKSLGNFFTIREVLERYDAEVVRFFIVRTHYRSPLNYSDVHLDDARAS
LTRLYTALKDVEPDTLALDWNEPHAQRFAAAMNDDFNTPVAVATLFELAGEVNRTRDASLARQLKQLAGLLGLLGREPRA
FLQQASGAAQAGGLAADEIEAQIAARVAAKQAKDYAEADRIRAELLEAGIALEDKPGGSTEWRRV

Specific function: Unknown

COG id: COG0215

COG function: function code J; Cysteinyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI13375695, Length=398, Percent_Identity=38.9447236180905, Blast_Score=246, Evalue=4e-65,
Organism=Homo sapiens, GI303304987, Length=280, Percent_Identity=36.4285714285714, Blast_Score=181, Evalue=1e-45,
Organism=Homo sapiens, GI21269877, Length=280, Percent_Identity=36.4285714285714, Blast_Score=181, Evalue=1e-45,
Organism=Homo sapiens, GI62240992, Length=280, Percent_Identity=36.4285714285714, Blast_Score=181, Evalue=1e-45,
Organism=Homo sapiens, GI10835051, Length=280, Percent_Identity=36.4285714285714, Blast_Score=181, Evalue=1e-45,
Organism=Escherichia coli, GI1786737, Length=467, Percent_Identity=56.3169164882227, Blast_Score=497, Evalue=1e-142,
Organism=Caenorhabditis elegans, GI17509795, Length=236, Percent_Identity=37.7118644067797, Blast_Score=166, Evalue=3e-41,
Organism=Caenorhabditis elegans, GI17509797, Length=236, Percent_Identity=37.7118644067797, Blast_Score=166, Evalue=3e-41,
Organism=Saccharomyces cerevisiae, GI6324082, Length=442, Percent_Identity=30.316742081448, Blast_Score=194, Evalue=2e-50,
Organism=Drosophila melanogaster, GI19922218, Length=391, Percent_Identity=37.3401534526854, Blast_Score=228, Evalue=8e-60,
Organism=Drosophila melanogaster, GI19922364, Length=338, Percent_Identity=33.7278106508876, Blast_Score=173, Evalue=3e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015803
- InterPro:   IPR015273
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF09190 DALR_2; PF01406 tRNA-synt_1e [H]

EC number: =6.1.1.16 [H]

Molecular weight: Translated: 52082; Mature: 52082

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESLRIYNTLARDKQVFVPRQPGEVRMYVCGITVYDYCHVGHARMLVVFDLVQRWLRAIG
CCCCHHHHHHHCCCEEECCCCCCCEEEEEECEEHHHHHHCCHHHHHHHHHHHHHHHHHHC
YRVTYVRNITDIDDKIIRRAVENGETIKSLTDRFIGAMHEDETALGIQRPDVEPRATQFI
CEEEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHH
PQMLGMIETLETNGYAYQAADGDVNYSVRKFADYGKLSGKSLDDLRAGERVAANDAKQDP
HHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHCCCCCCCHHHHHCCCCHHCCCCCCCC
LDFVLWKRAKADEPEGASWASKYGMGRPGWHIECSAMGCSLLGNHFDIHGGGQDLQFPHH
HHHHHHHHCCCCCCCCCCHHHHCCCCCCCCEEEEHHHCHHHHCCCEEECCCCCCCCCCCC
ENEIAQSEGATGETFVNYWMHNGFVQVDNEKMSKSLGNFFTIREVLERYDAEVVRFFIVR
CHHHHHCCCCCHHHHHHHHHHCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
THYRSPLNYSDVHLDDARASLTRLYTALKDVEPDTLALDWNEPHAQRFAAAMNDDFNTPV
HHHCCCCCCCCEECCHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHCCCCCCHH
AVATLFELAGEVNRTRDASLARQLKQLAGLLGLLGREPRAFLQQASGAAQAGGLAADEIE
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHCCCCCHHHHH
AQIAARVAAKQAKDYAEADRIRAELLEAGIALEDKPGGSTEWRRV
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCC
>Mature Secondary Structure
MESLRIYNTLARDKQVFVPRQPGEVRMYVCGITVYDYCHVGHARMLVVFDLVQRWLRAIG
CCCCHHHHHHHCCCEEECCCCCCCEEEEEECEEHHHHHHCCHHHHHHHHHHHHHHHHHHC
YRVTYVRNITDIDDKIIRRAVENGETIKSLTDRFIGAMHEDETALGIQRPDVEPRATQFI
CEEEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHH
PQMLGMIETLETNGYAYQAADGDVNYSVRKFADYGKLSGKSLDDLRAGERVAANDAKQDP
HHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHCCCCCCCHHHHHCCCCHHCCCCCCCC
LDFVLWKRAKADEPEGASWASKYGMGRPGWHIECSAMGCSLLGNHFDIHGGGQDLQFPHH
HHHHHHHHCCCCCCCCCCHHHHCCCCCCCCEEEEHHHCHHHHCCCEEECCCCCCCCCCCC
ENEIAQSEGATGETFVNYWMHNGFVQVDNEKMSKSLGNFFTIREVLERYDAEVVRFFIVR
CHHHHHCCCCCHHHHHHHHHHCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
THYRSPLNYSDVHLDDARASLTRLYTALKDVEPDTLALDWNEPHAQRFAAAMNDDFNTPV
HHHCCCCCCCCEECCHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHCCCCCCHH
AVATLFELAGEVNRTRDASLARQLKQLAGLLGLLGREPRAFLQQASGAAQAGGLAADEIE
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHCCCCCHHHHH
AQIAARVAAKQAKDYAEADRIRAELLEAGIALEDKPGGSTEWRRV
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA