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The map label for this gene is frr [H]

Identifier: 116690037

GI number: 116690037

Start: 2233058

End: 2233618

Strand: Reverse

Name: frr [H]

Synonym: Bcen2424_2016

Alternate gene names: 116690037

Gene position: 2233618-2233058 (Counterclockwise)

Preceding gene: 116690038

Following gene: 116690036

Centisome position: 64.11

GC content: 62.21

Gene sequence:

>561_bases
ATGAGTGTCGCTGATGTCAAGAAGGGCGTCGAGCAAAAGATGCAGCGCTCGATCGAAGCGTTCAAGAACGATCTGGCCAA
GATCCGTACGGGCCGTGCACACACCGGTCTGCTCGATCACGTGCAGGTCGACTACTACGGCTCGATGGTGCCGATCTCGC
AGGTCGCGAACCTGACGCTCGTCGACGCGCGCACGATCGGCGTGCAGCCGTGGGAAAAGAACATGGTCGCGAAGGTCGAG
AAGGCCATCCGCGAAGCCGATCTGGGCCTGAACCCGGCAACGACCGGCGACCTGATCCGCGTGCCGATGCCCGCGCTGAC
GGAAGAGCGCCGCCGCGAGCTGACCAAAGTCGTGAAGAGCGAAGGCGAAACGGCCAAGGTCGCGATCCGCAACCTGCGCC
GCGACGCGAACGAAGCGCTGAAGAAGCTCGTGAAGGACAAGGAAATCTCGGAAGACGACGAGCGCCGCGCGAGCGACGAC
GTGCAGAAGCTGACCGACAAGCACGTTGCCGAAATCGACAAGCTCGTGCAGACCAAGGAAGCCGAGATCATGACGGTCTG
A

Upstream 100 bases:

>100_bases
CACGTGTAAACTCCCGCGGATGCGGGCGACCGGCCGCGGCGCGCGACATGCGCCGGGCGGGGCCCGTGTTCTTTGAAGGT
TTGAAGGTTCGGAGGTTGAA

Downstream 100 bases:

>100_bases
CGACCGTCCTCGCGCGCCGCCTTCTTCCCGCATTACTGTCTCAACGGCCATGACCTATACCAGCTCTACCGTTCGCGTGC
CTGACGTCGGTGTCGTGCCG

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor [H]

Number of amino acids: Translated: 186; Mature: 185

Protein sequence:

>186_residues
MSVADVKKGVEQKMQRSIEAFKNDLAKIRTGRAHTGLLDHVQVDYYGSMVPISQVANLTLVDARTIGVQPWEKNMVAKVE
KAIREADLGLNPATTGDLIRVPMPALTEERRRELTKVVKSEGETAKVAIRNLRRDANEALKKLVKDKEISEDDERRASDD
VQKLTDKHVAEIDKLVQTKEAEIMTV

Sequences:

>Translated_186_residues
MSVADVKKGVEQKMQRSIEAFKNDLAKIRTGRAHTGLLDHVQVDYYGSMVPISQVANLTLVDARTIGVQPWEKNMVAKVE
KAIREADLGLNPATTGDLIRVPMPALTEERRRELTKVVKSEGETAKVAIRNLRRDANEALKKLVKDKEISEDDERRASDD
VQKLTDKHVAEIDKLVQTKEAEIMTV
>Mature_185_residues
SVADVKKGVEQKMQRSIEAFKNDLAKIRTGRAHTGLLDHVQVDYYGSMVPISQVANLTLVDARTIGVQPWEKNMVAKVEK
AIREADLGLNPATTGDLIRVPMPALTEERRRELTKVVKSEGETAKVAIRNLRRDANEALKKLVKDKEISEDDERRASDDV
QKLTDKHVAEIDKLVQTKEAEIMTV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another [H]

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family [H]

Homologues:

Organism=Homo sapiens, GI20270317, Length=177, Percent_Identity=32.2033898305085, Blast_Score=80, Evalue=9e-16,
Organism=Homo sapiens, GI291042689, Length=155, Percent_Identity=32.9032258064516, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI1786368, Length=182, Percent_Identity=52.7472527472528, Blast_Score=206, Evalue=8e-55,
Organism=Drosophila melanogaster, GI24661488, Length=182, Percent_Identity=29.1208791208791, Blast_Score=79, Evalue=2e-15,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002661
- InterPro:   IPR015998 [H]

Pfam domain/function: PF01765 RRF [H]

EC number: NA

Molecular weight: Translated: 20857; Mature: 20726

Theoretical pI: Translated: 8.89; Mature: 8.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVADVKKGVEQKMQRSIEAFKNDLAKIRTGRAHTGLLDHVQVDYYGSMVPISQVANLTL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCHHHHHCCCE
VDARTIGVQPWEKNMVAKVEKAIREADLGLNPATTGDLIRVPMPALTEERRRELTKVVKS
EEHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHC
EGETAKVAIRNLRRDANEALKKLVKDKEISEDDERRASDDVQKLTDKHVAEIDKLVQTKE
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
AEIMTV
CHHCCC
>Mature Secondary Structure 
SVADVKKGVEQKMQRSIEAFKNDLAKIRTGRAHTGLLDHVQVDYYGSMVPISQVANLTL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCHHHHHCCCE
VDARTIGVQPWEKNMVAKVEKAIREADLGLNPATTGDLIRVPMPALTEERRRELTKVVKS
EEHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHC
EGETAKVAIRNLRRDANEALKKLVKDKEISEDDERRASDDVQKLTDKHVAEIDKLVQTKE
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
AEIMTV
CHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA