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The map label for this gene is 116689948

Identifier: 116689948

GI number: 116689948

Start: 2142771

End: 2143769

Strand: Reverse

Name: 116689948

Synonym: Bcen2424_1927

Alternate gene names: NA

Gene position: 2143769-2142771 (Counterclockwise)

Preceding gene: 116689949

Following gene: 116689945

Centisome position: 61.53

GC content: 70.47

Gene sequence:

>999_bases
ATGAACGACACGAATTCAGGGTCGGTGCGCGCGGCGGTGGTTGGCGTCGGCGCGATCGGCGGATTGCTCGCGGCCGCGCT
GTCGAGAGCCGGCATGACCGTGAGCGCGTACGCACGGGGCACGACGCTCGACGCGCTGAATACGCACGGCGTGCGCGTGA
TCGACGAGGCGGGTGCAACCTCGTCGGTGCCGGTGCGGGCAAGCGACGATGCAGCCGCGCTCGGCGTGCAGGACTACGTG
GTGATCGCGCTGAAGGCGCAGGCGCTGCCGGCGCTGGCCGCCCGTATTGCGCCGCTGGTCGGCCCCGATACGGTGATCGT
CGCGGCGATGAACGGGCTGCCGTGGTGGTTCACGCACGGGCTGGAAGGGGCGATCGACGGCGTGCCGCTCGATGCGGTCG
ATCCGGCCGGCGCGGTGTCGGCCGCATTGCCGCCCGCGCAGGCGATCGGCTGCGTCGTGCACCTGTCGTCGAGTACCGAC
GCGCCGGGCGTCGTGCGTCGCGGGCGCGGCAACCGGCTGATCGTCGGCACGCCCGATCCGCGGCTCGACGTGGCCACCGC
GCGGTTCGCCGCGGCGCTCGCGGCCGGCGGTTTCGACGTCGAGTCGACGCCCGCGATCCGGGCCGAGATCTGGACGAAGC
TGTGGGGCAACATGAACATGAACCCGCTGAGCGCGCTGACCGGTTCGACGGCCGAACAGTTGCTCGACGATCCGTTCACG
CAGGATCTCGCACTGCGGATGATGGAGGAGGCGGCTGCGATCGGCGCGAAGCTCGGGCTATCCACGGGAATGAGCGGCCC
CGAGCGGATCGCGGTCACGCGCAAGCTCGGCGCATTCAAGACATCGATGCTGCAGGATTTCGAAGCGGGGCGCTCGCTCG
AGATCGGGCCGATCCTCGGCGTGTTTCCGGAGCTCGGCCGCAAGCTTGGCGTGCCGACCCCGTACTGCGACGCGGTGCTC
GGACTATTGCGTCAGCGCGCGGCGAACAGCGGGTTGTAG

Upstream 100 bases:

>100_bases
ACGAACGGATACGGCGCGATGCGCATTGCGTTGCCGGATTGGTTGTGTCCGCAACCATTGAGCGTTATGCTCGTCAGCTT
CCAGGAGACGGAATGCCATC

Downstream 100 bases:

>100_bases
CGCGTTGCCGGCTGCCGCATACGCGCAGCCGGCAACGCGGCGGTGCGTGCTTCACGCGATGCCGCCGCATGATGCAAAAC
GGGTCGCCCGAATCGCGCGT

Product: 2-dehydropantoate 2-reductase

Products: NA

Alternate protein names: Ketopantoate reductase; KPA reductase; KPR [H]

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MNDTNSGSVRAAVVGVGAIGGLLAAALSRAGMTVSAYARGTTLDALNTHGVRVIDEAGATSSVPVRASDDAAALGVQDYV
VIALKAQALPALAARIAPLVGPDTVIVAAMNGLPWWFTHGLEGAIDGVPLDAVDPAGAVSAALPPAQAIGCVVHLSSSTD
APGVVRRGRGNRLIVGTPDPRLDVATARFAAALAAGGFDVESTPAIRAEIWTKLWGNMNMNPLSALTGSTAEQLLDDPFT
QDLALRMMEEAAAIGAKLGLSTGMSGPERIAVTRKLGAFKTSMLQDFEAGRSLEIGPILGVFPELGRKLGVPTPYCDAVL
GLLRQRAANSGL

Sequences:

>Translated_332_residues
MNDTNSGSVRAAVVGVGAIGGLLAAALSRAGMTVSAYARGTTLDALNTHGVRVIDEAGATSSVPVRASDDAAALGVQDYV
VIALKAQALPALAARIAPLVGPDTVIVAAMNGLPWWFTHGLEGAIDGVPLDAVDPAGAVSAALPPAQAIGCVVHLSSSTD
APGVVRRGRGNRLIVGTPDPRLDVATARFAAALAAGGFDVESTPAIRAEIWTKLWGNMNMNPLSALTGSTAEQLLDDPFT
QDLALRMMEEAAAIGAKLGLSTGMSGPERIAVTRKLGAFKTSMLQDFEAGRSLEIGPILGVFPELGRKLGVPTPYCDAVL
GLLRQRAANSGL
>Mature_332_residues
MNDTNSGSVRAAVVGVGAIGGLLAAALSRAGMTVSAYARGTTLDALNTHGVRVIDEAGATSSVPVRASDDAAALGVQDYV
VIALKAQALPALAARIAPLVGPDTVIVAAMNGLPWWFTHGLEGAIDGVPLDAVDPAGAVSAALPPAQAIGCVVHLSSSTD
APGVVRRGRGNRLIVGTPDPRLDVATARFAAALAAGGFDVESTPAIRAEIWTKLWGNMNMNPLSALTGSTAEQLLDDPFT
QDLALRMMEEAAAIGAKLGLSTGMSGPERIAVTRKLGAFKTSMLQDFEAGRSLEIGPILGVFPELGRKLGVPTPYCDAVL
GLLRQRAANSGL

Specific function: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid [H]

COG id: COG1893

COG function: function code H; Ketopantoate reductase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ketopantoate reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR003710
- InterPro:   IPR013752
- InterPro:   IPR013332
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02558 ApbA; PF08546 ApbA_C [H]

EC number: =1.1.1.169 [H]

Molecular weight: Translated: 33861; Mature: 33861

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDTNSGSVRAAVVGVGAIGGLLAAALSRAGMTVSAYARGTTLDALNTHGVRVIDEAGAT
CCCCCCCCEEEEEEEHHHHHHHHHHHHHHCCCEEEEEECCCEECCCCCCCEEEEECCCCC
SSVPVRASDDAAALGVQDYVVIALKAQALPALAARIAPLVGPDTVIVAAMNGLPWWFTHG
CCCCEECCCCCHHCCCCCEEEEEEEHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHCC
LEGAIDGVPLDAVDPAGAVSAALPPAQAIGCVVHLSSSTDAPGVVRRGRGNRLIVGTPDP
CCCCCCCCCCCCCCCCCCHHHCCCCHHHEEEEEEECCCCCCCCHHCCCCCCEEEEECCCC
RLDVATARFAAALAAGGFDVESTPAIRAEIWTKLWGNMNMNPLSALTGSTAEQLLDDPFT
CCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHCCCHHHHHHCCCCH
QDLALRMMEEAAAIGAKLGLSTGMSGPERIAVTRKLGAFKTSMLQDFEAGRSLEIGPILG
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHEEHHHHHHHHHHHHHHHHHCCCCEECCHHHH
VFPELGRKLGVPTPYCDAVLGLLRQRAANSGL
HHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNDTNSGSVRAAVVGVGAIGGLLAAALSRAGMTVSAYARGTTLDALNTHGVRVIDEAGAT
CCCCCCCCEEEEEEEHHHHHHHHHHHHHHCCCEEEEEECCCEECCCCCCCEEEEECCCCC
SSVPVRASDDAAALGVQDYVVIALKAQALPALAARIAPLVGPDTVIVAAMNGLPWWFTHG
CCCCEECCCCCHHCCCCCEEEEEEEHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHCC
LEGAIDGVPLDAVDPAGAVSAALPPAQAIGCVVHLSSSTDAPGVVRRGRGNRLIVGTPDP
CCCCCCCCCCCCCCCCCCHHHCCCCHHHEEEEEEECCCCCCCCHHCCCCCCEEEEECCCC
RLDVATARFAAALAAGGFDVESTPAIRAEIWTKLWGNMNMNPLSALTGSTAEQLLDDPFT
CCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHCCCHHHHHHCCCCH
QDLALRMMEEAAAIGAKLGLSTGMSGPERIAVTRKLGAFKTSMLQDFEAGRSLEIGPILG
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHEEHHHHHHHHHHHHHHHHHCCCCEECCHHHH
VFPELGRKLGVPTPYCDAVLGLLRQRAANSGL
HHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]