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The map label for this gene is bcd [H]

Identifier: 116689363

GI number: 116689363

Start: 1478156

End: 1479985

Strand: Direct

Name: bcd [H]

Synonym: Bcen2424_1341

Alternate gene names: 116689363

Gene position: 1478156-1479985 (Clockwise)

Preceding gene: 116689362

Following gene: 116689364

Centisome position: 42.43

GC content: 68.25

Gene sequence:

>1830_bases
ATGAGTCTGTTGATGTCGCGACGCGATCTCGCGTTCCTGCTGTATGACTGGCTCGACGCCGAAGCGCTCGTCGCGCTGCC
GCGCTACGCGGAGCATAGTCGCGAGACCTTCGACGCGGTGCTCGACACCAGCGAGCGGATTGCCGAAGACCTGTTCGCGC
CGCACGCGGCGCGCGGCGATCGCGAGGAGCCGCGGTTCGACGGCGAACGCGTGACGCTGATCCCGGAAGTCGAGCCGGCC
GTGCGCGCGTTCGCGGACGCCGGGCTGATCGCCGCAGGTCACGACGAAGCGCTCGGCGGCATGCGCTTGCCGAAGCTCGT
CGAAGCCGCGTCGTTCCTGTTCTTCCAGGCCGCGAACATCGCGACCGCCGCGTATCCGTTCCTGACCGTCGCCAACGCGA
ACCTGCTCGTCGCGCACGGCAGCGCCGCGCAGATCGACGCGTTCGCGCGCCCGGAGCTGGAAGGGCGTTTCCTCGGCACG
ATGTGCCTGTCCGAACCGCAAGCCGGCTCGTCGCTGTCCGACATCGCGACGCGCGCCGATTTCGAAGGCGCTTCCCCGCT
CGGCCCGCGCTACCGGCTGACCGGCAACAAGATGTGGATTTCCGGCGGCGAGCACGAGCTGGCGGAAAACATCGTTCACC
TCGTGCTCGCGAAGATCCCCGACGAACATGGCCGGCTGCAGCCCGGCACGCGCGGCATCTCGCTGTTCATCGTGCCGAAG
TTCCTGACCGGCACCGATGGCGACGCGAGCGGTGAGCACAACGACGTCGTGCTCGCCGGGCTGAACCACAAGATGGGCTA
TCGCGGCACGACCAACTGTCTGCTGAATTTCGGCGAAGGGACGCGTTATCGGCCGGAAGGGCGCGCGGGTGCGATCGGTT
ATCTGGTCGGCCAGCCGAATCACGGCCTCGCCTACATGTTCCATATGATGAACGAGGCGCGTATCGGGGTCGGCGCGGGC
GCGGTGGCGCTCGGCTACACCGGTTATCTGCACGCGCTCGACTACGCGCGCAACCGCCCGCAAGGCCGCCCGCTCGGGCC
TGCGGCCAAGGATGCGGCCGCGCCGCAGGCACCGATCGTCGACCATCCGGACGTGCGGCGCATGCTGCTCGCGCAGAAGG
CCTATGTCGAAGGCGGTCTCGCGTTGATCCTGTACTGCGCGAAACTGGTCGACGAAGCGCGCGCGCACGGCGATGCGACG
GCGCGCGCCGAGGCTACGCGCCTGCTCGACATCCTGACGCCGATCGCGAAAAGCTGGCCGTCGCAGTGGTGTCTGGCCGC
GAACGATCTCGCGATCCAGGTGCACGGCGGCTACGGCTACACGCGCGACTACGCGGTCGAACGGCTCTATCGCGACAACC
GCCTGAATCCGATTCACGAAGGCACGCACGGCATCCAGGCGCTCGATCTGCTGGGCCGCAAGGTCACGCAGGACGACGGC
GCGTCGCTGCGCGCGCTCGATGCGCGGATCGGCGCGACCGTCGAGCGCGCGCGGGCACTGGATGCCGGCACGCGCGAGCA
GGCCGATGCGTTGGCGCAGCGTTGGGCGAGACTGTGCGACGTGACGCATCAGTTGAACGCGATCGGTGATCCGCGGACGC
GGCTGGCGAACGCGAGCGTGTATCTCGAAGCGTTCGGCCATCTCGTCGTTGCGTGGCTGTGGCTCGACGTGACGCTCGCC
GCGCACGGGCAGGACGGCGATTTCCACGACGGCAAGCGTGCGGCGGCCCGTTACTTCTTCCGCTGGGAATTGCCGAAGGT
GGATGCGCAGCTCGACCTGCTGTCGAGCGTCGACACGACGACGCTCGACATGCGCGACGCGTGGTTCTGA

Upstream 100 bases:

>100_bases
CGTTGTCGTTTGCGAACGACCGTGCTAAATTCCTGCCAGCGCTTGCAGTCACGCAACCCTTCATTCGGCTGACACGGCCG
GCAACCCGGGAGGCAGCACG

Downstream 100 bases:

>100_bases
ACGTGGTTTCAACGACATTCCGGAATACCGACGATCTCGCCGATGCGATGGTCATCGCATGCTCGTCGTGAACCGGCCGC
GCGGGGCCATCCCGCACACC

Product: acyl-CoA dehydrogenase domain-containing protein

Products: NA

Alternate protein names: Butyryl-CoA dehydrogenase; SCAD [H]

Number of amino acids: Translated: 609; Mature: 608

Protein sequence:

>609_residues
MSLLMSRRDLAFLLYDWLDAEALVALPRYAEHSRETFDAVLDTSERIAEDLFAPHAARGDREEPRFDGERVTLIPEVEPA
VRAFADAGLIAAGHDEALGGMRLPKLVEAASFLFFQAANIATAAYPFLTVANANLLVAHGSAAQIDAFARPELEGRFLGT
MCLSEPQAGSSLSDIATRADFEGASPLGPRYRLTGNKMWISGGEHELAENIVHLVLAKIPDEHGRLQPGTRGISLFIVPK
FLTGTDGDASGEHNDVVLAGLNHKMGYRGTTNCLLNFGEGTRYRPEGRAGAIGYLVGQPNHGLAYMFHMMNEARIGVGAG
AVALGYTGYLHALDYARNRPQGRPLGPAAKDAAAPQAPIVDHPDVRRMLLAQKAYVEGGLALILYCAKLVDEARAHGDAT
ARAEATRLLDILTPIAKSWPSQWCLAANDLAIQVHGGYGYTRDYAVERLYRDNRLNPIHEGTHGIQALDLLGRKVTQDDG
ASLRALDARIGATVERARALDAGTREQADALAQRWARLCDVTHQLNAIGDPRTRLANASVYLEAFGHLVVAWLWLDVTLA
AHGQDGDFHDGKRAAARYFFRWELPKVDAQLDLLSSVDTTTLDMRDAWF

Sequences:

>Translated_609_residues
MSLLMSRRDLAFLLYDWLDAEALVALPRYAEHSRETFDAVLDTSERIAEDLFAPHAARGDREEPRFDGERVTLIPEVEPA
VRAFADAGLIAAGHDEALGGMRLPKLVEAASFLFFQAANIATAAYPFLTVANANLLVAHGSAAQIDAFARPELEGRFLGT
MCLSEPQAGSSLSDIATRADFEGASPLGPRYRLTGNKMWISGGEHELAENIVHLVLAKIPDEHGRLQPGTRGISLFIVPK
FLTGTDGDASGEHNDVVLAGLNHKMGYRGTTNCLLNFGEGTRYRPEGRAGAIGYLVGQPNHGLAYMFHMMNEARIGVGAG
AVALGYTGYLHALDYARNRPQGRPLGPAAKDAAAPQAPIVDHPDVRRMLLAQKAYVEGGLALILYCAKLVDEARAHGDAT
ARAEATRLLDILTPIAKSWPSQWCLAANDLAIQVHGGYGYTRDYAVERLYRDNRLNPIHEGTHGIQALDLLGRKVTQDDG
ASLRALDARIGATVERARALDAGTREQADALAQRWARLCDVTHQLNAIGDPRTRLANASVYLEAFGHLVVAWLWLDVTLA
AHGQDGDFHDGKRAAARYFFRWELPKVDAQLDLLSSVDTTTLDMRDAWF
>Mature_608_residues
SLLMSRRDLAFLLYDWLDAEALVALPRYAEHSRETFDAVLDTSERIAEDLFAPHAARGDREEPRFDGERVTLIPEVEPAV
RAFADAGLIAAGHDEALGGMRLPKLVEAASFLFFQAANIATAAYPFLTVANANLLVAHGSAAQIDAFARPELEGRFLGTM
CLSEPQAGSSLSDIATRADFEGASPLGPRYRLTGNKMWISGGEHELAENIVHLVLAKIPDEHGRLQPGTRGISLFIVPKF
LTGTDGDASGEHNDVVLAGLNHKMGYRGTTNCLLNFGEGTRYRPEGRAGAIGYLVGQPNHGLAYMFHMMNEARIGVGAGA
VALGYTGYLHALDYARNRPQGRPLGPAAKDAAAPQAPIVDHPDVRRMLLAQKAYVEGGLALILYCAKLVDEARAHGDATA
RAEATRLLDILTPIAKSWPSQWCLAANDLAIQVHGGYGYTRDYAVERLYRDNRLNPIHEGTHGIQALDLLGRKVTQDDGA
SLRALDARIGATVERARALDAGTREQADALAQRWARLCDVTHQLNAIGDPRTRLANASVYLEAFGHLVVAWLWLDVTLAA
HGQDGDFHDGKRAAARYFFRWELPKVDAQLDLLSSVDTTTLDMRDAWF

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501859, Length=398, Percent_Identity=27.1356783919598, Blast_Score=103, Evalue=5e-22,
Organism=Homo sapiens, GI4557233, Length=441, Percent_Identity=27.6643990929705, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI7656849, Length=382, Percent_Identity=25.130890052356, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI4501857, Length=393, Percent_Identity=24.6819338422392, Blast_Score=87, Evalue=6e-17,
Organism=Homo sapiens, GI4557235, Length=355, Percent_Identity=26.4788732394366, Blast_Score=83, Evalue=8e-16,
Organism=Homo sapiens, GI76496475, Length=354, Percent_Identity=26.5536723163842, Blast_Score=83, Evalue=8e-16,
Organism=Escherichia coli, GI87082384, Length=385, Percent_Identity=26.4935064935065, Blast_Score=88, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17508101, Length=406, Percent_Identity=22.9064039408867, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI86563383, Length=557, Percent_Identity=22.8007181328546, Blast_Score=82, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI86563381, Length=557, Percent_Identity=22.8007181328546, Blast_Score=82, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17506239, Length=339, Percent_Identity=23.3038348082596, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17505929, Length=387, Percent_Identity=26.3565891472868, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21356377, Length=475, Percent_Identity=25.8947368421053, Blast_Score=104, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24666513, Length=443, Percent_Identity=24.6049661399549, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24646207, Length=438, Percent_Identity=25.5707762557078, Blast_Score=83, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: =1.3.99.2 [H]

Molecular weight: Translated: 66339; Mature: 66208

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: PS00073 ACYL_COA_DH_2 ; PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLLMSRRDLAFLLYDWLDAEALVALPRYAEHSRETFDAVLDTSERIAEDLFAPHAARGD
CCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCC
REEPRFDGERVTLIPEVEPAVRAFADAGLIAAGHDEALGGMRLPKLVEAASFLFFQAANI
CCCCCCCCCEEEEECCCCHHHHHHHCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHH
ATAAYPFLTVANANLLVAHGSAAQIDAFARPELEGRFLGTMCLSEPQAGSSLSDIATRAD
HHHHCCEEEEECCEEEEECCCCHHHHHCCCCCCCCEEEEHHHCCCCCCCCCHHHHHHHCC
FEGASPLGPRYRLTGNKMWISGGEHELAENIVHLVLAKIPDEHGRLQPGTRGISLFIVPK
CCCCCCCCCCEEEECCEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEE
FLTGTDGDASGEHNDVVLAGLNHKMGYRGTTNCLLNFGEGTRYRPEGRAGAIGYLVGQPN
EECCCCCCCCCCCCCEEEEECCCCCCCCCCCHHEEECCCCCCCCCCCCCCEEEEEECCCC
HGLAYMFHMMNEARIGVGAGAVALGYTGYLHALDYARNRPQGRPLGPAAKDAAAPQAPIV
CCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHCCCCCCCCC
DHPDVRRMLLAQKAYVEGGLALILYCAKLVDEARAHGDATARAEATRLLDILTPIAKSWP
CCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCC
SQWCLAANDLAIQVHGGYGYTRDYAVERLYRDNRLNPIHEGTHGIQALDLLGRKVTQDDG
CCEEEEECCEEEEEECCCCCHHHHHHHHHHHCCCCCCHHCCCHHHHHHHHHCCCCCCCCC
ASLRALDARIGATVERARALDAGTREQADALAQRWARLCDVTHQLNAIGDPRTRLANASV
CCEEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCHHH
YLEAFGHLVVAWLWLDVTLAAHGQDGDFHDGKRAAARYFFRWELPKVDAQLDLLSSVDTT
HHHHHHHHHHHHHHHHHHEEECCCCCCCCCCHHHHHHEEEEECCCCCCHHHHHHHCCCCC
TLDMRDAWF
EECCCCCCC
>Mature Secondary Structure 
SLLMSRRDLAFLLYDWLDAEALVALPRYAEHSRETFDAVLDTSERIAEDLFAPHAARGD
CCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCC
REEPRFDGERVTLIPEVEPAVRAFADAGLIAAGHDEALGGMRLPKLVEAASFLFFQAANI
CCCCCCCCCEEEEECCCCHHHHHHHCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHH
ATAAYPFLTVANANLLVAHGSAAQIDAFARPELEGRFLGTMCLSEPQAGSSLSDIATRAD
HHHHCCEEEEECCEEEEECCCCHHHHHCCCCCCCCEEEEHHHCCCCCCCCCHHHHHHHCC
FEGASPLGPRYRLTGNKMWISGGEHELAENIVHLVLAKIPDEHGRLQPGTRGISLFIVPK
CCCCCCCCCCEEEECCEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEE
FLTGTDGDASGEHNDVVLAGLNHKMGYRGTTNCLLNFGEGTRYRPEGRAGAIGYLVGQPN
EECCCCCCCCCCCCCEEEEECCCCCCCCCCCHHEEECCCCCCCCCCCCCCEEEEEECCCC
HGLAYMFHMMNEARIGVGAGAVALGYTGYLHALDYARNRPQGRPLGPAAKDAAAPQAPIV
CCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHCCCCCCCCC
DHPDVRRMLLAQKAYVEGGLALILYCAKLVDEARAHGDATARAEATRLLDILTPIAKSWP
CCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCC
SQWCLAANDLAIQVHGGYGYTRDYAVERLYRDNRLNPIHEGTHGIQALDLLGRKVTQDDG
CCEEEEECCEEEEEECCCCCHHHHHHHHHHHCCCCCCHHCCCHHHHHHHHHCCCCCCCCC
ASLRALDARIGATVERARALDAGTREQADALAQRWARLCDVTHQLNAIGDPRTRLANASV
CCEEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCHHH
YLEAFGHLVVAWLWLDVTLAAHGQDGDFHDGKRAAARYFFRWELPKVDAQLDLLSSVDTT
HHHHHHHHHHHHHHHHHHEEECCCCCCCCCCHHHHHHEEEEECCCCCCHHHHHHHCCCCC
TLDMRDAWF
EECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]