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The map label for this gene is mdtA [H]

Identifier: 116689220

GI number: 116689220

Start: 1321019

End: 1322392

Strand: Reverse

Name: mdtA [H]

Synonym: Bcen2424_1198

Alternate gene names: 116689220

Gene position: 1322392-1321019 (Counterclockwise)

Preceding gene: 116689221

Following gene: 116689219

Centisome position: 37.96

GC content: 68.49

Gene sequence:

>1374_bases
ATGGATAACGAACAAAAGCCCACGCCCCCTTCGAAAGACTCCGCGCCCGCCGCTGCACGGCGCCCGCGCCGCACGCTGCT
GATCGGCACCGTCGCGGTCGTCGTCATCGGCGGCCTGCTGTGGTGGCATCCGTGGAACCGCACGCCCGCGACAGGCAGTT
CGGCGCAAGGCGCGGGCGCCAGCGCGGCCGCAGGCAGCCATCGCGGCCGCGGCGGCCCCGCTGCAATGGCGAACGTTCCG
CAGCCGGTGCAGGTCGCCCCCGTGACGCAGGGCGAGATGCCGATCGTGCTGTCCGCGCTCGGCACCGTCACGCCGCTCGC
GAACGTGACGGTCAAGACGCAGTTGTCGGGCTACCTGCAGTCGGTGTCGTTCCAGGAAGGCCAGATCGTCAAGAAAGGCG
ACGTGCTCGCGCAGATCGACCCGCGCCCGTACCAGGTCGCGCTCGAGAACGCCGAAGGCACGCATGCGCGCGACGCGGCG
CTGCTCGCGACGGCCCGCCTCGACCTGAAGCGCTACCAGACGCTGCTGTCGCAGGACTCGATCGCGTCGCAAACCGTCGA
TACGCAGGCATCGCTCGTCAAGCAATACGAAGGCGCGGTGAAGACCGACCAGGCCGCGATCGATTCCGCGAAACTCAATC
TCACCTATGCGCGCATCACGGCGCCGGTCTCCGGCCGCGTCGGCCTGCGCCAGGTCGACCCCGGCAACTACGTGACGCCG
GGCGACACCAACGGCATCGTCGTGATCACGCAGTTGCAGCCGATGAGCGTGATCTTCACGACGTCGGAAGACAACCTGCC
GCAGATCCTCAAGCAGGTGAACGCCGGCCAGAAGCTGTCGGTCACCGCCTACAACCGCAACAACACCGTGCCGCTCGAAA
CGGGCTCGCTCGCGACGCTCGACAACCAGATCGACACGAGCACCGGCACGGTCAAGCTGCGCGCGAACTTCGATAACAAG
GAAGGCATGCTGTTCCCGAATCAGTTCGTGAACACGCGGCTGCTCGTCGACGTGATGCGCAACGCGACGATCGTGCCGAC
CTCCGCCGTGCTGACGGGGTCGATCGGCCAGTTCGTCTATGTCGTGAAACCCGACAACACGGTGACGGTGCGCAAGGTCA
CGGTCGGCCCGGTCGACGGCGAACGCACGAGCATCGTCAGCGGCGTGACGCTCGGCGAGCGCGTGGTGACCGACGGCTCG
GACCGTCTGCGCGAAGGCTCGAAGATCTCGATTCCGGCCGACAAGCCGAAGGGCGCATCGGGCGCGCGCGGCGCAGGGGC
CGCATCGGGTGCATCGGCTGCGTCCGGTGCCGGCGGCCATCGCGGCGGACACCGGCACGGCGCGTCGCAAGCCGCGGCCC
CCGCGGCCCAGTAA

Upstream 100 bases:

>100_bases
CGGACCGAGCCGGGCCGCCCCGTCCCGTCACCCGCACGCCCACGCGCAGCCCAGCAGTCCGATTTTCCGGCCCGCCGCGC
CGTCTTCCTGACAGAACACG

Downstream 100 bases:

>100_bases
CGCGCGGGCCGCTCGATGAATCCATCCCGCCTCTTCATTCTCCGGCCGGTCGGTACCGCTCTCCTGATGGCGGCGATCAT
GCTGGCCGGCCTCGTCGCGC

Product: RND family efflux transporter MFP subunit

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 457; Mature: 457

Protein sequence:

>457_residues
MDNEQKPTPPSKDSAPAAARRPRRTLLIGTVAVVVIGGLLWWHPWNRTPATGSSAQGAGASAAAGSHRGRGGPAAMANVP
QPVQVAPVTQGEMPIVLSALGTVTPLANVTVKTQLSGYLQSVSFQEGQIVKKGDVLAQIDPRPYQVALENAEGTHARDAA
LLATARLDLKRYQTLLSQDSIASQTVDTQASLVKQYEGAVKTDQAAIDSAKLNLTYARITAPVSGRVGLRQVDPGNYVTP
GDTNGIVVITQLQPMSVIFTTSEDNLPQILKQVNAGQKLSVTAYNRNNTVPLETGSLATLDNQIDTSTGTVKLRANFDNK
EGMLFPNQFVNTRLLVDVMRNATIVPTSAVLTGSIGQFVYVVKPDNTVTVRKVTVGPVDGERTSIVSGVTLGERVVTDGS
DRLREGSKISIPADKPKGASGARGAGAASGASAASGAGGHRGGHRHGASQAAAPAAQ

Sequences:

>Translated_457_residues
MDNEQKPTPPSKDSAPAAARRPRRTLLIGTVAVVVIGGLLWWHPWNRTPATGSSAQGAGASAAAGSHRGRGGPAAMANVP
QPVQVAPVTQGEMPIVLSALGTVTPLANVTVKTQLSGYLQSVSFQEGQIVKKGDVLAQIDPRPYQVALENAEGTHARDAA
LLATARLDLKRYQTLLSQDSIASQTVDTQASLVKQYEGAVKTDQAAIDSAKLNLTYARITAPVSGRVGLRQVDPGNYVTP
GDTNGIVVITQLQPMSVIFTTSEDNLPQILKQVNAGQKLSVTAYNRNNTVPLETGSLATLDNQIDTSTGTVKLRANFDNK
EGMLFPNQFVNTRLLVDVMRNATIVPTSAVLTGSIGQFVYVVKPDNTVTVRKVTVGPVDGERTSIVSGVTLGERVVTDGS
DRLREGSKISIPADKPKGASGARGAGAASGASAASGAGGHRGGHRHGASQAAAPAAQ
>Mature_457_residues
MDNEQKPTPPSKDSAPAAARRPRRTLLIGTVAVVVIGGLLWWHPWNRTPATGSSAQGAGASAAAGSHRGRGGPAAMANVP
QPVQVAPVTQGEMPIVLSALGTVTPLANVTVKTQLSGYLQSVSFQEGQIVKKGDVLAQIDPRPYQVALENAEGTHARDAA
LLATARLDLKRYQTLLSQDSIASQTVDTQASLVKQYEGAVKTDQAAIDSAKLNLTYARITAPVSGRVGLRQVDPGNYVTP
GDTNGIVVITQLQPMSVIFTTSEDNLPQILKQVNAGQKLSVTAYNRNNTVPLETGSLATLDNQIDTSTGTVKLRANFDNK
EGMLFPNQFVNTRLLVDVMRNATIVPTSAVLTGSIGQFVYVVKPDNTVTVRKVTVGPVDGERTSIVSGVTLGERVVTDGS
DRLREGSKISIPADKPKGASGARGAGAASGASAASGAGGHRGGHRHGASQAAAPAAQ

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=374, Percent_Identity=44.9197860962567, Blast_Score=328, Evalue=3e-91,
Organism=Escherichia coli, GI1789929, Length=358, Percent_Identity=28.7709497206704, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI1789665, Length=315, Percent_Identity=32.3809523809524, Blast_Score=135, Evalue=6e-33,
Organism=Escherichia coli, GI1786668, Length=326, Percent_Identity=32.2085889570552, Blast_Score=132, Evalue=5e-32,
Organism=Escherichia coli, GI87081796, Length=341, Percent_Identity=26.6862170087977, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI87081951, Length=205, Percent_Identity=27.3170731707317, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 47536; Mature: 47536

Theoretical pI: Translated: 10.27; Mature: 10.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNEQKPTPPSKDSAPAAARRPRRTLLIGTVAVVVIGGLLWWHPWNRTPATGSSAQGAGA
CCCCCCCCCCCCCCCCHHHCCCCEEEEHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCC
SAAAGSHRGRGGPAAMANVPQPVQVAPVTQGEMPIVLSALGTVTPLANVTVKTQLSGYLQ
CCCCCCCCCCCCCHHHCCCCCCCEEEECCCCCCCCHHHHHHHHCCCCCEEEEEHHHHHHH
SVSFQEGQIVKKGDVLAQIDPRPYQVALENAEGTHARDAALLATARLDLKRYQTLLSQDS
HCCCCCCCEEECCCEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCH
IASQTVDTQASLVKQYEGAVKTDQAAIDSAKLNLTYARITAPVSGRVGLRQVDPGNYVTP
HHHHHHHHHHHHHHHHCCCCCCCHHHHCCEEEEEEEEEEECCCCCCCCEEEECCCCEECC
GDTNGIVVITQLQPMSVIFTTSEDNLPQILKQVNAGQKLSVTAYNRNNTVPLETGSLATL
CCCCCEEEEEECCCEEEEEECCCCCHHHHHHHHCCCCEEEEEEECCCCEEEECCCCEEEE
DNQIDTSTGTVKLRANFDNKEGMLFPNQFVNTRLLVDVMRNATIVPTSAVLTGSIGQFVY
CCCCCCCCCEEEEEECCCCCCCEECCHHHHHHHHHHHHHHCCEECCCHHHEECCCCCEEE
VVKPDNTVTVRKVTVGPVDGERTSIVSGVTLGERVVTDGSDRLREGSKISIPADKPKGAS
EECCCCEEEEEEEEECCCCCCCCEEEECCCCCCEEECCCHHHHCCCCEEECCCCCCCCCC
GARGAGAASGASAASGAGGHRGGHRHGASQAAAPAAQ
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MDNEQKPTPPSKDSAPAAARRPRRTLLIGTVAVVVIGGLLWWHPWNRTPATGSSAQGAGA
CCCCCCCCCCCCCCCCHHHCCCCEEEEHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCC
SAAAGSHRGRGGPAAMANVPQPVQVAPVTQGEMPIVLSALGTVTPLANVTVKTQLSGYLQ
CCCCCCCCCCCCCHHHCCCCCCCEEEECCCCCCCCHHHHHHHHCCCCCEEEEEHHHHHHH
SVSFQEGQIVKKGDVLAQIDPRPYQVALENAEGTHARDAALLATARLDLKRYQTLLSQDS
HCCCCCCCEEECCCEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCH
IASQTVDTQASLVKQYEGAVKTDQAAIDSAKLNLTYARITAPVSGRVGLRQVDPGNYVTP
HHHHHHHHHHHHHHHHCCCCCCCHHHHCCEEEEEEEEEEECCCCCCCCEEEECCCCEECC
GDTNGIVVITQLQPMSVIFTTSEDNLPQILKQVNAGQKLSVTAYNRNNTVPLETGSLATL
CCCCCEEEEEECCCEEEEEECCCCCHHHHHHHHCCCCEEEEEEECCCCEEEECCCCEEEE
DNQIDTSTGTVKLRANFDNKEGMLFPNQFVNTRLLVDVMRNATIVPTSAVLTGSIGQFVY
CCCCCCCCCEEEEEECCCCCCCEECCHHHHHHHHHHHHHHCCEECCCHHHEECCCCCEEE
VVKPDNTVTVRKVTVGPVDGERTSIVSGVTLGERVVTDGSDRLREGSKISIPADKPKGAS
EECCCCEEEEEEEEECCCCCCCCEEEECCCCCCEEECCCHHHHCCCCEEECCCCCCCCCC
GARGAGAASGASAASGAGGHRGGHRHGASQAAAPAAQ
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA