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The map label for this gene is bphD [H]

Identifier: 116689190

GI number: 116689190

Start: 1282110

End: 1283171

Strand: Direct

Name: bphD [H]

Synonym: Bcen2424_1168

Alternate gene names: 116689190

Gene position: 1282110-1283171 (Clockwise)

Preceding gene: 116689186

Following gene: 116689192

Centisome position: 36.8

GC content: 67.8

Gene sequence:

>1062_bases
ATGCTTTCGATTTGCAAGATGTTGTCCGTCGCACGTGCCGCCGTGCTCGGCGCGAGTGCCGCCGCCGCGTGCGCGATGCC
GGTTGCGGCCGTTGCGGCCACGCCCGCCGCCAACGACGGGCCCGCTTACGGCCCGCGCCTGGAAGGATTCGCGTATCCGG
CGCCCGTGCATGAGTACGCGTTCGTGTCGCAACGCGAAACCCTCGAGATGGCGTACCTCGACGTGCAGCCCGCGCATCCG
AACGGTCGCACCGTCGTGCTGCTGCACGGCAAGAACTTCTGCGCGGCGACCTGGGAGGACACGATCGGTGTGCTGAGCCG
CGCCGGTTATCGCGTGATCGCGCCGGACCAGATCGGCTTCTGCAAGTCGTCGAAGCCCGAGCGCTACCAGTACAGCTTCC
AGCAACTCGCGCGCAACACGCACGCGCTGCTCGAATCGGTCGGCGTGAAGTCGGCGACGATCATCGGCCACTCGACGGGC
GGGATGCTCGCGATCCGCTATGCGCTGATGTATCCGAAGGCGACCGACCAGCTCGTGCTCGTGAACCCGATCGGCCTCGA
GGACTGGAAGGCGCTCGGCGTGCCGCCGCTGTCGGTCGACTACTGGTATGCGCGCGAACTGAAGACCAACGCCGACGGCA
TCCGCCGCTACGAGCAGTCGACCTACTACGCGGGCAAGTGGGCGCCGTCGTACGAGCGCTGGGTGCAGATGCTCGCCGGG
ATGTATCGCGGCGCCGGCCGCGACGCGGTCGCGTGGAATTCCGCGCTGATCTACGACATGATCCTCACGCAGCCGGTGGT
CTACGAACTCGGCGCGATTCGCGTGCCGACGCTGCTGATGATCGGCGACAAGGATACGACCGCGATCGGCAAGGATGTCG
CCCCGCCCGACGTGCACGCGAAGCTCGGCCGCTATCCTGAGCTCGCGAAGCGCACGCAGGCCGCGATTCCCGGCGCGCAG
CTCGTCGAATTTCCGGCGCTCGGACACGCGCCGCAGATCCAGGACCCGGACGCGTTCCACAAGGCGCTGCTCGACGGGCT
GGAGGCCGTGCACCCGCAGTGA

Upstream 100 bases:

>100_bases
GTTGCGCGCCGTCGTCACGCGACCGCGTAGAATCGCGGGGCGCGAGACAGCCCCGCTGGGGCCCGGCTGCCCGCGCGCGT
CCCCAATCACCGTGATCGCC

Downstream 100 bases:

>100_bases
CGCGGGGCAGGCGGCAGGCCGCGCGTAATCGTGCGGTCAGCGTGCCTCGCTCGCGAGCTCGTCGCGGATCTGCGCGGTCA
GTTCGAACGAGCGCAGCCGC

Product: alpha/beta hydrolase fold

Products: NA

Alternate protein names: HOPDA hydrolase; 2,6-dioxo-6-phenylhexa-3-enoate hydrolase [H]

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MLSICKMLSVARAAVLGASAAAACAMPVAAVAATPAANDGPAYGPRLEGFAYPAPVHEYAFVSQRETLEMAYLDVQPAHP
NGRTVVLLHGKNFCAATWEDTIGVLSRAGYRVIAPDQIGFCKSSKPERYQYSFQQLARNTHALLESVGVKSATIIGHSTG
GMLAIRYALMYPKATDQLVLVNPIGLEDWKALGVPPLSVDYWYARELKTNADGIRRYEQSTYYAGKWAPSYERWVQMLAG
MYRGAGRDAVAWNSALIYDMILTQPVVYELGAIRVPTLLMIGDKDTTAIGKDVAPPDVHAKLGRYPELAKRTQAAIPGAQ
LVEFPALGHAPQIQDPDAFHKALLDGLEAVHPQ

Sequences:

>Translated_353_residues
MLSICKMLSVARAAVLGASAAAACAMPVAAVAATPAANDGPAYGPRLEGFAYPAPVHEYAFVSQRETLEMAYLDVQPAHP
NGRTVVLLHGKNFCAATWEDTIGVLSRAGYRVIAPDQIGFCKSSKPERYQYSFQQLARNTHALLESVGVKSATIIGHSTG
GMLAIRYALMYPKATDQLVLVNPIGLEDWKALGVPPLSVDYWYARELKTNADGIRRYEQSTYYAGKWAPSYERWVQMLAG
MYRGAGRDAVAWNSALIYDMILTQPVVYELGAIRVPTLLMIGDKDTTAIGKDVAPPDVHAKLGRYPELAKRTQAAIPGAQ
LVEFPALGHAPQIQDPDAFHKALLDGLEAVHPQ
>Mature_353_residues
MLSICKMLSVARAAVLGASAAAACAMPVAAVAATPAANDGPAYGPRLEGFAYPAPVHEYAFVSQRETLEMAYLDVQPAHP
NGRTVVLLHGKNFCAATWEDTIGVLSRAGYRVIAPDQIGFCKSSKPERYQYSFQQLARNTHALLESVGVKSATIIGHSTG
GMLAIRYALMYPKATDQLVLVNPIGLEDWKALGVPPLSVDYWYARELKTNADGIRRYEQSTYYAGKWAPSYERWVQMLAG
MYRGAGRDAVAWNSALIYDMILTQPVVYELGAIRVPTLLMIGDKDTTAIGKDVAPPDVHAKLGRYPELAKRTQAAIPGAQ
LVEFPALGHAPQIQDPDAFHKALLDGLEAVHPQ

Specific function: Catalyzes an unusual C-C bond hydrolysis of 2-hydroxy-6- oxo-6-phenylhexa-2,4-dienoic acid (HOPDA) to produce benzoic acid and 2-hydroxy-2,4-pentadienoic acid (HPD) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. BphD family [H]

Homologues:

Organism=Homo sapiens, GI27597073, Length=127, Percent_Identity=34.6456692913386, Blast_Score=65, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR017727 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.7.1.8 [H]

Molecular weight: Translated: 38297; Mature: 38297

Theoretical pI: Translated: 7.62; Mature: 7.62

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSICKMLSVARAAVLGASAAAACAMPVAAVAATPAANDGPAYGPRLEGFAYPAPVHEYA
CHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHH
FVSQRETLEMAYLDVQPAHPNGRTVVLLHGKNFCAATWEDTIGVLSRAGYRVIAPDQIGF
HHHCHHHEEEEEEEEECCCCCCCEEEEEECCCCEEECHHHHHHHHHHCCCEEECCCCCCC
CKSSKPERYQYSFQQLARNTHALLESVGVKSATIIGHSTGGMLAIRYALMYPKATDQLVL
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHCCCCCCCEEE
VNPIGLEDWKALGVPPLSVDYWYARELKTNADGIRRYEQSTYYAGKWAPSYERWVQMLAG
EECCCCCCHHHCCCCCCCCCHHHHHHHHCCHHHHHHHHHCCEECCCCCCCHHHHHHHHHH
MYRGAGRDAVAWNSALIYDMILTQPVVYELGAIRVPTLLMIGDKDTTAIGKDVAPPDVHA
HHCCCCCCCCCCCHHHHHHHHHHCHHHHHHCCCCCCEEEEECCCCCHHCCCCCCCCCHHH
KLGRYPELAKRTQAAIPGAQLVEFPALGHAPQIQDPDAFHKALLDGLEAVHPQ
HHCCCHHHHHHHHHCCCCHHHEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLSICKMLSVARAAVLGASAAAACAMPVAAVAATPAANDGPAYGPRLEGFAYPAPVHEYA
CHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHH
FVSQRETLEMAYLDVQPAHPNGRTVVLLHGKNFCAATWEDTIGVLSRAGYRVIAPDQIGF
HHHCHHHEEEEEEEEECCCCCCCEEEEEECCCCEEECHHHHHHHHHHCCCEEECCCCCCC
CKSSKPERYQYSFQQLARNTHALLESVGVKSATIIGHSTGGMLAIRYALMYPKATDQLVL
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHCCCCCCCEEE
VNPIGLEDWKALGVPPLSVDYWYARELKTNADGIRRYEQSTYYAGKWAPSYERWVQMLAG
EECCCCCCHHHCCCCCCCCCHHHHHHHHCCHHHHHHHHHCCEECCCCCCCHHHHHHHHHH
MYRGAGRDAVAWNSALIYDMILTQPVVYELGAIRVPTLLMIGDKDTTAIGKDVAPPDVHA
HHCCCCCCCCCCCHHHHHHHHHHCHHHHHHCCCCCCEEEEECCCCCHHCCCCCCCCCHHH
KLGRYPELAKRTQAAIPGAQLVEFPALGHAPQIQDPDAFHKALLDGLEAVHPQ
HHCCCHHHHHHHHHCCCCHHHEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA