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The map label for this gene is 116689080

Identifier: 116689080

GI number: 116689080

Start: 1171665

End: 1172588

Strand: Direct

Name: 116689080

Synonym: Bcen2424_1057

Alternate gene names: NA

Gene position: 1171665-1172588 (Clockwise)

Preceding gene: 116689078

Following gene: 116689082

Centisome position: 33.63

GC content: 66.56

Gene sequence:

>924_bases
ATGGCAACCGCTTTCTACACGCACCCCGACTGCATGCTGCACGAGATGGGGGAATGGCATCCGGAATGCCCGGCCCGCTT
GTCGGCGATCCAGGATCAACTGATTGCGAGCCGCATCGACGACCTGATCGTGCACGAAACCGCGCCATTCGCGAGCGAGG
TCGCGCTGGGTCGCGTGCATACGCAGGCGCACATCGACTACATCCGGAGCATGACGCCGGTCGACGGTCACGTCGAGATC
GATCCCGATACGCTGATGAATCGCGACACGTGGCGCGCGGCGCTGCGCGCGGCCGGCGCCGCGATCGCGGCGACCGACGC
GGTGATCGAAGGCCGCTATGCGAATGCGTTCTGCGGCGTCCGTCCACCCGGTCACCATGCGGAACCCGCGCGCGCGATGG
GCTTCTGCTTCTTCAACAACGTCGCGATCGCCGCGCGGCATGCACTCGACGTACACGGCATCGAGCGTGTCGCGATCATC
GATTTCGACGTGCACCACGGCAACGGCACCGAGGCGGCGTTCGCGAACGACGAGCGCGTGCTGATGTGCAGCTTCTTCCA
GCATCCGCTGTATCCGTTCTCGGGCGTCGATCATCAGGCGCCGAACATGGTCAACCTGCCGATGCCCGCGCGCAGCAACG
GGATGGCGATCCGCGAAGCCGTCGACATGTTCTGGCTGCCGCGCCTCGATGCGTTCAAGCCGCAGATGCTGTTCGTGTCG
GCCGGGTTCGATGCGCATCGCGAGGACGACATCGGCAATCTCGGCCTCGTCGAGGCCGACTTCGAATGGCTGACCGCCCA
GATCGTCGACGTCGCGCGCCGGCATGCGCAGGGCCGCATCGTCAGCTGCCTCGAGGGCGGCTACAACCTGTCCGCGCTCG
GGCGCAGCGTCGTCGCGCACCTGCGCGTGCTGGCCGGGATCTGA

Upstream 100 bases:

>100_bases
AGCCGGCCCCCGTTGTGGTAAGTTAGCGGCGAATTCGCGGCAGACGATGGACATCATTGACGGAGACCTGCGGCGCACCG
TGCGCCGCGGACGACAGCTT

Downstream 100 bases:

>100_bases
TTCCCGCTCGACCGGCCGGGCCGGGCGCGCTCAGCGCGCCGGCACGCGCGCGTGAATCCACGCGATCAGCGCGTCGATCA
CGCGGTCGCGTTCGAGATCG

Product: histone deacetylase superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 306

Protein sequence:

>307_residues
MATAFYTHPDCMLHEMGEWHPECPARLSAIQDQLIASRIDDLIVHETAPFASEVALGRVHTQAHIDYIRSMTPVDGHVEI
DPDTLMNRDTWRAALRAAGAAIAATDAVIEGRYANAFCGVRPPGHHAEPARAMGFCFFNNVAIAARHALDVHGIERVAII
DFDVHHGNGTEAAFANDERVLMCSFFQHPLYPFSGVDHQAPNMVNLPMPARSNGMAIREAVDMFWLPRLDAFKPQMLFVS
AGFDAHREDDIGNLGLVEADFEWLTAQIVDVARRHAQGRIVSCLEGGYNLSALGRSVVAHLRVLAGI

Sequences:

>Translated_307_residues
MATAFYTHPDCMLHEMGEWHPECPARLSAIQDQLIASRIDDLIVHETAPFASEVALGRVHTQAHIDYIRSMTPVDGHVEI
DPDTLMNRDTWRAALRAAGAAIAATDAVIEGRYANAFCGVRPPGHHAEPARAMGFCFFNNVAIAARHALDVHGIERVAII
DFDVHHGNGTEAAFANDERVLMCSFFQHPLYPFSGVDHQAPNMVNLPMPARSNGMAIREAVDMFWLPRLDAFKPQMLFVS
AGFDAHREDDIGNLGLVEADFEWLTAQIVDVARRHAQGRIVSCLEGGYNLSALGRSVVAHLRVLAGI
>Mature_306_residues
ATAFYTHPDCMLHEMGEWHPECPARLSAIQDQLIASRIDDLIVHETAPFASEVALGRVHTQAHIDYIRSMTPVDGHVEID
PDTLMNRDTWRAALRAAGAAIAATDAVIEGRYANAFCGVRPPGHHAEPARAMGFCFFNNVAIAARHALDVHGIERVAIID
FDVHHGNGTEAAFANDERVLMCSFFQHPLYPFSGVDHQAPNMVNLPMPARSNGMAIREAVDMFWLPRLDAFKPQMLFVSA
GFDAHREDDIGNLGLVEADFEWLTAQIVDVARRHAQGRIVSCLEGGYNLSALGRSVVAHLRVLAGI

Specific function: Putative deacetylase [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI13128864, Length=307, Percent_Identity=34.8534201954397, Blast_Score=154, Evalue=8e-38,
Organism=Homo sapiens, GI20070354, Length=330, Percent_Identity=35.4545454545455, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI17158039, Length=331, Percent_Identity=32.3262839879154, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI30795204, Length=331, Percent_Identity=32.3262839879154, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI30795202, Length=331, Percent_Identity=32.3262839879154, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI226529806, Length=327, Percent_Identity=32.7217125382263, Blast_Score=130, Evalue=1e-30,
Organism=Homo sapiens, GI153085395, Length=257, Percent_Identity=35.408560311284, Blast_Score=121, Evalue=6e-28,
Organism=Homo sapiens, GI62750347, Length=238, Percent_Identity=35.2941176470588, Blast_Score=120, Evalue=1e-27,
Organism=Homo sapiens, GI62750349, Length=238, Percent_Identity=35.2941176470588, Blast_Score=120, Evalue=1e-27,
Organism=Homo sapiens, GI148539870, Length=251, Percent_Identity=34.2629482071713, Blast_Score=114, Evalue=9e-26,
Organism=Homo sapiens, GI169234807, Length=251, Percent_Identity=34.2629482071713, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI217272877, Length=269, Percent_Identity=26.7657992565056, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI13128862, Length=275, Percent_Identity=21.8181818181818, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17540334, Length=306, Percent_Identity=33.0065359477124, Blast_Score=153, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI17540332, Length=306, Percent_Identity=33.0065359477124, Blast_Score=151, Evalue=4e-37,
Organism=Caenorhabditis elegans, GI193206283, Length=306, Percent_Identity=33.0065359477124, Blast_Score=151, Evalue=4e-37,
Organism=Caenorhabditis elegans, GI25154020, Length=297, Percent_Identity=32.6599326599327, Blast_Score=138, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI25154022, Length=299, Percent_Identity=32.7759197324415, Blast_Score=137, Evalue=7e-33,
Organism=Caenorhabditis elegans, GI193209491, Length=325, Percent_Identity=32.3076923076923, Blast_Score=136, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17537347, Length=308, Percent_Identity=32.4675324675325, Blast_Score=136, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17534739, Length=328, Percent_Identity=24.6951219512195, Blast_Score=88, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6324307, Length=318, Percent_Identity=32.7044025157233, Blast_Score=152, Evalue=6e-38,
Organism=Saccharomyces cerevisiae, GI6325141, Length=301, Percent_Identity=24.9169435215947, Blast_Score=82, Evalue=9e-17,
Organism=Saccharomyces cerevisiae, GI6323999, Length=278, Percent_Identity=22.6618705035971, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6321244, Length=267, Percent_Identity=23.9700374531835, Blast_Score=70, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6325325, Length=176, Percent_Identity=24.4318181818182, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24642146, Length=317, Percent_Identity=35.3312302839117, Blast_Score=159, Evalue=3e-39,
Organism=Drosophila melanogaster, GI24642142, Length=317, Percent_Identity=35.3312302839117, Blast_Score=158, Evalue=3e-39,
Organism=Drosophila melanogaster, GI24642144, Length=317, Percent_Identity=35.3312302839117, Blast_Score=158, Evalue=4e-39,
Organism=Drosophila melanogaster, GI281360899, Length=317, Percent_Identity=35.0157728706625, Blast_Score=158, Evalue=4e-39,
Organism=Drosophila melanogaster, GI281360801, Length=330, Percent_Identity=32.1212121212121, Blast_Score=121, Evalue=5e-28,
Organism=Drosophila melanogaster, GI24641720, Length=330, Percent_Identity=32.1212121212121, Blast_Score=121, Evalue=5e-28,
Organism=Drosophila melanogaster, GI281360799, Length=330, Percent_Identity=32.1212121212121, Blast_Score=121, Evalue=5e-28,
Organism=Drosophila melanogaster, GI24657891, Length=273, Percent_Identity=24.5421245421245, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24649807, Length=292, Percent_Identity=26.3698630136986, Blast_Score=68, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000286 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 33764; Mature: 33633

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATAFYTHPDCMLHEMGEWHPECPARLSAIQDQLIASRIDDLIVHETAPFASEVALGRVH
CCCEEECCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
TQAHIDYIRSMTPVDGHVEIDPDTLMNRDTWRAALRAAGAAIAATDAVIEGRYANAFCGV
HHHHHHHHHHCCCCCCEEEECHHHHCCCHHHHHHHHHCCCHHHHHHHHHCCCCCCEECCC
RPPGHHAEPARAMGFCFFNNVAIAARHALDVHGIERVAIIDFDVHHGNGTEAAFANDERV
CCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCEECCCCEE
LMCSFFQHPLYPFSGVDHQAPNMVNLPMPARSNGMAIREAVDMFWLPRLDAFKPQMLFVS
EEEEHHCCCCCCCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCEEEEEE
AGFDAHREDDIGNLGLVEADFEWLTAQIVDVARRHAQGRIVSCLEGGYNLSALGRSVVAH
CCCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHCCCEEEEHHCCCCHHHHHHHHHHH
LRVLAGI
HHHHHCC
>Mature Secondary Structure 
ATAFYTHPDCMLHEMGEWHPECPARLSAIQDQLIASRIDDLIVHETAPFASEVALGRVH
CCEEECCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
TQAHIDYIRSMTPVDGHVEIDPDTLMNRDTWRAALRAAGAAIAATDAVIEGRYANAFCGV
HHHHHHHHHHCCCCCCEEEECHHHHCCCHHHHHHHHHCCCHHHHHHHHHCCCCCCEECCC
RPPGHHAEPARAMGFCFFNNVAIAARHALDVHGIERVAIIDFDVHHGNGTEAAFANDERV
CCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCEECCCCEE
LMCSFFQHPLYPFSGVDHQAPNMVNLPMPARSNGMAIREAVDMFWLPRLDAFKPQMLFVS
EEEEHHCCCCCCCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCEEEEEE
AGFDAHREDDIGNLGLVEADFEWLTAQIVDVARRHAQGRIVSCLEGGYNLSALGRSVVAH
CCCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHCCCEEEEHHCCCCHHHHHHHHHHH
LRVLAGI
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]