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The map label for this gene is cysM [H]

Identifier: 116689078

GI number: 116689078

Start: 1169223

End: 1170200

Strand: Direct

Name: cysM [H]

Synonym: Bcen2424_1055

Alternate gene names: 116689078

Gene position: 1169223-1170200 (Clockwise)

Preceding gene: 116689077

Following gene: 116689080

Centisome position: 33.56

GC content: 64.42

Gene sequence:

>978_bases
ATGGGGTTGCCGGCGCGGGTGCCGGTGCTGGTTTACAATCGATCGATTGATCGGCCTCGCACTCACGGTATATCCATGGC
TTACAAAACTATCGAAGACACGATCGGCAATACGCCGCTCGTGCAACTGGTCCGCCTGCCGGACGACGAGATTCGCGCCC
GCAACAACGTGCTGCTCGCGAAGCTCGAGGGCAACAATCCGGCCGGCTCCGTGAAGGATCGCCCGGCGCTGTCGATGATC
AGCAAGGCCGAGGCGCGCGGGCGCATCAAGCCGGGCGATACGCTGATCGAGGCGACGAGCGGCAACACGGGCATCGCGCT
CGCGATGGCCGCGGCGATCCGCGGCTACAAGATGGTGCTGATCATGCCGGAGGATCTGTCGGTCGAGCGCCGCCAGAGCA
TGGCCGCTTATGGTGCCGAGATCATCCTGACGCCGGTGAAGGGCGGGATGGAGCTGGCGCGCGACCTCGCGGAGCAGATG
CAGCGTGAAGGCAAGGGCGTGATCCTCGACCAGTTCGGCAACCCCGACAATCCCGTCGCGCACTACGAAGCAACGGGGCC
GGAGATCTGGCGCGATACCGAAGGGCGCATCACGCACTTCGTGTCCGCCATGGGCACGACGGGCACCATCATGGGCACGT
CGCGCTATCTGAAGGAACAGAATCCGGCGATCGAGATCGTCGGTGCGCAGCCGGAAGACGGCTCGCGTATTCCGGGCATC
CGCAAATGGCCGGAAGCGTACATGCCGACCATCTTCGATCGCAGCCGTGTCGACCGCGTCGAGAGCGTGAGCCAGGCTGC
GTCGGAAACGATGACGCGCCGGCTCGCGGCGGTCGAAGGCATTTTCGCGGGCATTTCGTCGGGCGGCGCATGCGAAGTCG
CGATGCGTATCGCGCGTCAGGTCGAGAATGCGACGATCGTGTTCATCGTTTGCGATCGTGGCGACCGCTATCTGTCCACG
GGTGTGTTTCCCGCCTGA

Upstream 100 bases:

>100_bases
GTCGTTGCGACGGCTTCCCGCGGCATGCCGCGGGTTTTTTGCGTGGAGCGGCGTGCGTGGCGAACCGCGAACCGCGCGGC
ACGCGTATTCCATCGTCGCA

Downstream 100 bases:

>100_bases
GCGAGATCGGTGCGCGAGGCGCGCATCGATAAAAAAAGCGCCGCTTCTGCGGCGCTTTTTCTTTGGGCGGCCAGCGCTTA
CTGCGGCTGCTCGTCGGCAG

Product: cysteine synthase B

Products: NA

Alternate protein names: CSase B; O-acetylserine (thiol)-lyase B; OAS-TL B; O-acetylserine sulfhydrylase B [H]

Number of amino acids: Translated: 325; Mature: 324

Protein sequence:

>325_residues
MGLPARVPVLVYNRSIDRPRTHGISMAYKTIEDTIGNTPLVQLVRLPDDEIRARNNVLLAKLEGNNPAGSVKDRPALSMI
SKAEARGRIKPGDTLIEATSGNTGIALAMAAAIRGYKMVLIMPEDLSVERRQSMAAYGAEIILTPVKGGMELARDLAEQM
QREGKGVILDQFGNPDNPVAHYEATGPEIWRDTEGRITHFVSAMGTTGTIMGTSRYLKEQNPAIEIVGAQPEDGSRIPGI
RKWPEAYMPTIFDRSRVDRVESVSQAASETMTRRLAAVEGIFAGISSGGACEVAMRIARQVENATIVFIVCDRGDRYLST
GVFPA

Sequences:

>Translated_325_residues
MGLPARVPVLVYNRSIDRPRTHGISMAYKTIEDTIGNTPLVQLVRLPDDEIRARNNVLLAKLEGNNPAGSVKDRPALSMI
SKAEARGRIKPGDTLIEATSGNTGIALAMAAAIRGYKMVLIMPEDLSVERRQSMAAYGAEIILTPVKGGMELARDLAEQM
QREGKGVILDQFGNPDNPVAHYEATGPEIWRDTEGRITHFVSAMGTTGTIMGTSRYLKEQNPAIEIVGAQPEDGSRIPGI
RKWPEAYMPTIFDRSRVDRVESVSQAASETMTRRLAAVEGIFAGISSGGACEVAMRIARQVENATIVFIVCDRGDRYLST
GVFPA
>Mature_324_residues
GLPARVPVLVYNRSIDRPRTHGISMAYKTIEDTIGNTPLVQLVRLPDDEIRARNNVLLAKLEGNNPAGSVKDRPALSMIS
KAEARGRIKPGDTLIEATSGNTGIALAMAAAIRGYKMVLIMPEDLSVERRQSMAAYGAEIILTPVKGGMELARDLAEQMQ
REGKGVILDQFGNPDNPVAHYEATGPEIWRDTEGRITHFVSAMGTTGTIMGTSRYLKEQNPAIEIVGAQPEDGSRIPGIR
KWPEAYMPTIFDRSRVDRVESVSQAASETMTRRLAAVEGIFAGISSGGACEVAMRIARQVENATIVFIVCDRGDRYLSTG
VFPA

Specific function: Two Cysteine Synthase Enzymes Are Found. Both Catalyze The Same Reaction. Cysteine Synthase B Can Also Use Thiosulfate In Place Of Sulfide To Give Cysteine Thiosulfonate As A Product. [C]

COG id: COG0031

COG function: function code E; Cysteine synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cysteine synthase/cystathionine beta- synthase family [H]

Homologues:

Organism=Homo sapiens, GI295821202, Length=307, Percent_Identity=38.1107491856677, Blast_Score=184, Evalue=9e-47,
Organism=Homo sapiens, GI295821200, Length=307, Percent_Identity=38.1107491856677, Blast_Score=184, Evalue=9e-47,
Organism=Homo sapiens, GI4557415, Length=307, Percent_Identity=38.1107491856677, Blast_Score=184, Evalue=9e-47,
Organism=Escherichia coli, GI2367138, Length=295, Percent_Identity=62.3728813559322, Blast_Score=370, Evalue=1e-104,
Organism=Escherichia coli, GI1788754, Length=317, Percent_Identity=41.9558359621451, Blast_Score=199, Evalue=2e-52,
Organism=Caenorhabditis elegans, GI17562970, Length=302, Percent_Identity=43.046357615894, Blast_Score=215, Evalue=2e-56,
Organism=Caenorhabditis elegans, GI17535051, Length=305, Percent_Identity=41.6393442622951, Blast_Score=215, Evalue=3e-56,
Organism=Caenorhabditis elegans, GI32566674, Length=297, Percent_Identity=43.7710437710438, Blast_Score=213, Evalue=1e-55,
Organism=Caenorhabditis elegans, GI115535073, Length=300, Percent_Identity=39.6666666666667, Blast_Score=201, Evalue=5e-52,
Organism=Caenorhabditis elegans, GI17561720, Length=302, Percent_Identity=40.7284768211921, Blast_Score=189, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI25147552, Length=318, Percent_Identity=35.8490566037736, Blast_Score=149, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI17534315, Length=317, Percent_Identity=36.5930599369085, Blast_Score=148, Evalue=5e-36,
Organism=Caenorhabditis elegans, GI32566672, Length=212, Percent_Identity=38.2075471698113, Blast_Score=140, Evalue=8e-34,
Organism=Saccharomyces cerevisiae, GI6321594, Length=316, Percent_Identity=39.2405063291139, Blast_Score=181, Evalue=2e-46,
Organism=Saccharomyces cerevisiae, GI6321449, Length=354, Percent_Identity=31.0734463276836, Blast_Score=124, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24643623, Length=308, Percent_Identity=38.6363636363636, Blast_Score=176, Evalue=1e-44,
Organism=Drosophila melanogaster, GI20129101, Length=308, Percent_Identity=38.6363636363636, Blast_Score=176, Evalue=1e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001216
- InterPro:   IPR005856
- InterPro:   IPR005858
- InterPro:   IPR001926 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =2.5.1.47 [H]

Molecular weight: Translated: 35297; Mature: 35166

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: PS00901 CYS_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLPARVPVLVYNRSIDRPRTHGISMAYKTIEDTIGNTPLVQLVRLPDDEIRARNNVLLA
CCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCHHHHCCCCEEEE
KLEGNNPAGSVKDRPALSMISKAEARGRIKPGDTLIEATSGNTGIALAMAAAIRGYKMVL
EEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHCCEEEEE
IMPEDLSVERRQSMAAYGAEIILTPVKGGMELARDLAEQMQREGKGVILDQFGNPDNPVA
EECCCCCHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCEE
HYEATGPEIWRDTEGRITHFVSAMGTTGTIMGTSRYLKEQNPAIEIVGAQPEDGSRIPGI
EEECCCCHHHCCCCCHHHHHHHHCCCCCEEECCHHHHHCCCCEEEEEECCCCCCCCCCCC
RKWPEAYMPTIFDRSRVDRVESVSQAASETMTRRLAAVEGIFAGISSGGACEVAMRIARQ
CCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
VENATIVFIVCDRGDRYLSTGVFPA
HCCCEEEEEEECCCCCEECCCCCCC
>Mature Secondary Structure 
GLPARVPVLVYNRSIDRPRTHGISMAYKTIEDTIGNTPLVQLVRLPDDEIRARNNVLLA
CCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCHHHHCCCCEEEE
KLEGNNPAGSVKDRPALSMISKAEARGRIKPGDTLIEATSGNTGIALAMAAAIRGYKMVL
EEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHCCEEEEE
IMPEDLSVERRQSMAAYGAEIILTPVKGGMELARDLAEQMQREGKGVILDQFGNPDNPVA
EECCCCCHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCEE
HYEATGPEIWRDTEGRITHFVSAMGTTGTIMGTSRYLKEQNPAIEIVGAQPEDGSRIPGI
EEECCCCHHHCCCCCHHHHHHHHCCCCCEEECCHHHHHCCCCEEEEEECCCCCCCCCCCC
RKWPEAYMPTIFDRSRVDRVESVSQAASETMTRRLAAVEGIFAGISSGGACEVAMRIARQ
CCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
VENATIVFIVCDRGDRYLSTGVFPA
HCCCEEEEEEECCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]