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The map label for this gene is hldD [H]

Identifier: 116689076

GI number: 116689076

Start: 1167670

End: 1168662

Strand: Direct

Name: hldD [H]

Synonym: Bcen2424_1053

Alternate gene names: 116689076

Gene position: 1167670-1168662 (Clockwise)

Preceding gene: 116689075

Following gene: 116689077

Centisome position: 33.52

GC content: 63.04

Gene sequence:

>993_bases
ATGACCCTCATCGTCACCGGCGCAGCCGGTTTTATCGGCGCGAACATCGTCAAGGCGCTCAACGAGCGCGGCGAGACGCG
CATCATCGCGGTCGACAACCTGACCCGCGCGGACAAGTTCCGCAATCTCGTCGACTGCGAGATCGACGACTATCTCGACA
AGACCGAATTCGTCGAACGCTTCGCGCGTGGCGATTTCGGCAAGGTGCGCGCGGTATTTCATGAAGGCGCCTGTTCGGAC
ACGATGGAAACCGACGGCCGCTACATGATGGACAACAACTTCCGCTACAGCCGCGCGGTGCTCGATACCTGCCTCGCGCA
GGGCACGCAGTTCCTGTATGCGTCGTCGGCCGCGATCTACGGCGGCTCGACGCGTTTCGTCGAGGAGCGCGACGTCGAGG
CGCCGCTGAACGTGTACGGCTATTCGAAGTTCCTGTTCGACCAGGTGATCCGTCGCGTGCTGCCGAGCGCGAAGAGCCAG
ATCGCGGGCTTCCGCTATTTCAACGTGTACGGCCCGCGCGAGACGCACAAGGGTCGCATGGCGTCGGTCGCGTTCCACAA
CTTCAACCAGTTCCGCGCGGAAGGCAAGGTGAAGCTGTTCGGCGAGTACAACGGTTATGCGCCGGGCGAGCAGACGCGCG
ATTTCGTGTCGGTCGAGGACGTGACCAAGGTGAACCTGTTCTTCTTCGATCATCCGGAGAAGTCGGGCATCTTCAACCTC
GGCACGGGGCGGGCGCAGCCGTTCAACGATATCGCGTCGACGGTCGTGAACACGCTGCGTGCGCTCGACAACCAGGCGCC
GCTGACGCTCGCGCAGCAGGTCGAGCAGGGGTTGATCGAATACGTGCCGTTCCCCGATGCACTGCGCGGCAAGTACCAGT
GCTTCACGCAGGCCGACCAGACGAAACTGCGCGCGGCCGGCTACGACGCACCGTTCCTGACCGTGCAGGAAGGCGTCGAC
CGCTACGTGCGTTGGCTATCCGGCCAGGTTTAA

Upstream 100 bases:

>100_bases
ACGGCCACGGTGGATTACGACGAACTGTTTCACTGAGCGCATTCGGCGGCGCGACGAGCGCGCCGCACGAGTGGCTCGCA
CTTTTTCAGGCAGGACGATC

Downstream 100 bases:

>100_bases
ACCGAAGCGTTGCATCGATAGACTGGGTCTCACGGTCGGCAGCCGCCGGCCGTTTTTCTTCGGAGATCCAGCACATGATC
AGGAAATGGTTTGCCGCAGC

Product: ADP-L-glycero-D-manno-heptose-6-epimerase

Products: NA

Alternate protein names: ADP-L-glycero-beta-D-manno-heptose-6-epimerase; ADP-glyceromanno-heptose 6-epimerase; ADP-hep 6-epimerase; AGME [H]

Number of amino acids: Translated: 330; Mature: 329

Protein sequence:

>330_residues
MTLIVTGAAGFIGANIVKALNERGETRIIAVDNLTRADKFRNLVDCEIDDYLDKTEFVERFARGDFGKVRAVFHEGACSD
TMETDGRYMMDNNFRYSRAVLDTCLAQGTQFLYASSAAIYGGSTRFVEERDVEAPLNVYGYSKFLFDQVIRRVLPSAKSQ
IAGFRYFNVYGPRETHKGRMASVAFHNFNQFRAEGKVKLFGEYNGYAPGEQTRDFVSVEDVTKVNLFFFDHPEKSGIFNL
GTGRAQPFNDIASTVVNTLRALDNQAPLTLAQQVEQGLIEYVPFPDALRGKYQCFTQADQTKLRAAGYDAPFLTVQEGVD
RYVRWLSGQV

Sequences:

>Translated_330_residues
MTLIVTGAAGFIGANIVKALNERGETRIIAVDNLTRADKFRNLVDCEIDDYLDKTEFVERFARGDFGKVRAVFHEGACSD
TMETDGRYMMDNNFRYSRAVLDTCLAQGTQFLYASSAAIYGGSTRFVEERDVEAPLNVYGYSKFLFDQVIRRVLPSAKSQ
IAGFRYFNVYGPRETHKGRMASVAFHNFNQFRAEGKVKLFGEYNGYAPGEQTRDFVSVEDVTKVNLFFFDHPEKSGIFNL
GTGRAQPFNDIASTVVNTLRALDNQAPLTLAQQVEQGLIEYVPFPDALRGKYQCFTQADQTKLRAAGYDAPFLTVQEGVD
RYVRWLSGQV
>Mature_329_residues
TLIVTGAAGFIGANIVKALNERGETRIIAVDNLTRADKFRNLVDCEIDDYLDKTEFVERFARGDFGKVRAVFHEGACSDT
METDGRYMMDNNFRYSRAVLDTCLAQGTQFLYASSAAIYGGSTRFVEERDVEAPLNVYGYSKFLFDQVIRRVLPSAKSQI
AGFRYFNVYGPRETHKGRMASVAFHNFNQFRAEGKVKLFGEYNGYAPGEQTRDFVSVEDVTKVNLFFFDHPEKSGIFNLG
TGRAQPFNDIASTVVNTLRALDNQAPLTLAQQVEQGLIEYVPFPDALRGKYQCFTQADQTKLRAAGYDAPFLTVQEGVDR
YVRWLSGQV

Specific function: Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose [H]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family. HldD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790049, Length=327, Percent_Identity=56.8807339449541, Blast_Score=352, Evalue=3e-98,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR011912
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.20 [H]

Molecular weight: Translated: 37133; Mature: 37002

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLIVTGAAGFIGANIVKALNERGETRIIAVDNLTRADKFRNLVDCEIDDYLDKTEFVER
CEEEEECCCHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHCCCHHHHCCHHHHHHH
FARGDFGKVRAVFHEGACSDTMETDGRYMMDNNFRYSRAVLDTCLAQGTQFLYASSAAIY
HHCCCHHHHHHHHHCCCCCCCHHCCCCEEECCCCHHHHHHHHHHHHCCCCEEEECCEEEE
GGSTRFVEERDVEAPLNVYGYSKFLFDQVIRRVLPSAKSQIAGFRYFNVYGPRETHKGRM
CCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHCCEEEEEECCCCCCCCCCE
ASVAFHNFNQFRAEGKVKLFGEYNGYAPGEQTRDFVSVEDVTKVNLFFFDHPEKSGIFNL
EEHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHCCCCCCCCEEEEEEEEECCCCCCEEEC
GTGRAQPFNDIASTVVNTLRALDNQAPLTLAQQVEQGLIEYVPFPDALRGKYQCFTQADQ
CCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHCCCHHHHCCHHH
TKLRAAGYDAPFLTVQEGVDRYVRWLSGQV
HHHHHCCCCCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TLIVTGAAGFIGANIVKALNERGETRIIAVDNLTRADKFRNLVDCEIDDYLDKTEFVER
EEEEECCCHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHCCCHHHHCCHHHHHHH
FARGDFGKVRAVFHEGACSDTMETDGRYMMDNNFRYSRAVLDTCLAQGTQFLYASSAAIY
HHCCCHHHHHHHHHCCCCCCCHHCCCCEEECCCCHHHHHHHHHHHHCCCCEEEECCEEEE
GGSTRFVEERDVEAPLNVYGYSKFLFDQVIRRVLPSAKSQIAGFRYFNVYGPRETHKGRM
CCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHCCEEEEEECCCCCCCCCCE
ASVAFHNFNQFRAEGKVKLFGEYNGYAPGEQTRDFVSVEDVTKVNLFFFDHPEKSGIFNL
EEHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHCCCCCCCCEEEEEEEEECCCCCCEEEC
GTGRAQPFNDIASTVVNTLRALDNQAPLTLAQQVEQGLIEYVPFPDALRGKYQCFTQADQ
CCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHCCCHHHHCCHHH
TKLRAAGYDAPFLTVQEGVDRYVRWLSGQV
HHHHHCCCCCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA