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The map label for this gene is qseD [H]

Identifier: 116688690

GI number: 116688690

Start: 742506

End: 743471

Strand: Direct

Name: qseD [H]

Synonym: Bcen2424_0667

Alternate gene names: 116688690

Gene position: 742506-743471 (Clockwise)

Preceding gene: 116688688

Following gene: 116688691

Centisome position: 21.31

GC content: 70.29

Gene sequence:

>966_bases
ATGGAACTGAAATGGCTCGAAGACTTCGTCTCGCTCGCGGAGACGCGCAGCTTTAGCCGGTCCGCCGAGCTGCGGCACGT
GTCGCAGCCGGCGTTTTCGCGACGCATCCAGGCGCTCGAGGCGTGGCTCGCGACCGAGCTGATCGATCGTTCGGTCTATC
CGACGCGGCTCACGCAGGCCGGGCAGATCTTCTACGAGCAGGCGCTGACGATGCTGTCGCAGGCGCACGAGGCGCGCACG
CTGCTGCGCGGCCACGTCGGCGCGCCGGTGCCGACGATCGAATTCGCGGTGCCGCACACGCTGTCGCTCACGTATTTCCC
GCGCTGGCTCGAGCGGATCGAGGCGAAGATGGGCCAGGTCCATACGCGGCTGCGCGCGCTGAACGTGCACGACGCGGTGC
TGTCGCTGGTCGAGGGCGGCTGCGACCTCGTGATGGGCTATCACCACCCGAGCCACCCGGTCGCGCTCGACCCGGCCCGC
TACGACATGCTGATCCTCGGCAGCGAGCCGATCAGCCCGTTCTCGGCGCCCGGTCGCGCGGGCCGGCCGCGCCATACGCT
GCCGGGCGCGGCGGACGCGCGCGTGCCGTACCTGTCGTATACGCCGAACGCGTATCTCGGCCGGATGACCGAAGTCATCA
TCGCGAACGCGCCGACGCGGCTGTTTCTCGATCGCGTCTACGAAACCGACATGGCCGAGGGGCTGAAGGCGATGGCGCTC
GCGGGCCACGGCGTCGCGTTCCTGCCGCACAGCGCGGTCGACGATGCGGTCGCGGGCGGCCGGCTGATCCGGCTCGACCG
GTCGGCGCGCGGCGGTGCGCATCCGTTCACGCTGACGATGGAGATCCGGCTGTACTGCGACAAGCTCGCGCTGCAGGGCG
ACGATCCGCGGCAGAAGCTCGTGCGGGCGCTGTGGGACGTCGTGCGCGACGAACTGCGCGACACGACCGGCGACGCCGCC
GCTTGA

Upstream 100 bases:

>100_bases
CCGCGCCGGCTTGCCGGGCCGCGTTCGACGCCGCCGGCCGGCCCCGCCCGCCGGTAGAATGCAGGCTTCTTCCCGACCGC
CGCCCGCCGCGCCCGCCTGC

Downstream 100 bases:

>100_bases
TCGCCGGATAGCCGCCGACGGTTAATCCGGCCGATCGGCTCGGCCGGCTGACGGCGCCCCGCAGCGCCTGTCGGACGGCT
GTCCCGTCGCCGGCTCGCGC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Quorum-sensing regulator protein D [H]

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MELKWLEDFVSLAETRSFSRSAELRHVSQPAFSRRIQALEAWLATELIDRSVYPTRLTQAGQIFYEQALTMLSQAHEART
LLRGHVGAPVPTIEFAVPHTLSLTYFPRWLERIEAKMGQVHTRLRALNVHDAVLSLVEGGCDLVMGYHHPSHPVALDPAR
YDMLILGSEPISPFSAPGRAGRPRHTLPGAADARVPYLSYTPNAYLGRMTEVIIANAPTRLFLDRVYETDMAEGLKAMAL
AGHGVAFLPHSAVDDAVAGGRLIRLDRSARGGAHPFTLTMEIRLYCDKLALQGDDPRQKLVRALWDVVRDELRDTTGDAA
A

Sequences:

>Translated_321_residues
MELKWLEDFVSLAETRSFSRSAELRHVSQPAFSRRIQALEAWLATELIDRSVYPTRLTQAGQIFYEQALTMLSQAHEART
LLRGHVGAPVPTIEFAVPHTLSLTYFPRWLERIEAKMGQVHTRLRALNVHDAVLSLVEGGCDLVMGYHHPSHPVALDPAR
YDMLILGSEPISPFSAPGRAGRPRHTLPGAADARVPYLSYTPNAYLGRMTEVIIANAPTRLFLDRVYETDMAEGLKAMAL
AGHGVAFLPHSAVDDAVAGGRLIRLDRSARGGAHPFTLTMEIRLYCDKLALQGDDPRQKLVRALWDVVRDELRDTTGDAA
A
>Mature_321_residues
MELKWLEDFVSLAETRSFSRSAELRHVSQPAFSRRIQALEAWLATELIDRSVYPTRLTQAGQIFYEQALTMLSQAHEART
LLRGHVGAPVPTIEFAVPHTLSLTYFPRWLERIEAKMGQVHTRLRALNVHDAVLSLVEGGCDLVMGYHHPSHPVALDPAR
YDMLILGSEPISPFSAPGRAGRPRHTLPGAADARVPYLSYTPNAYLGRMTEVIIANAPTRLFLDRVYETDMAEGLKAMAL
AGHGVAFLPHSAVDDAVAGGRLIRLDRSARGGAHPFTLTMEIRLYCDKLALQGDDPRQKLVRALWDVVRDELRDTTGDAA
A

Specific function: Down-regulates expression of the flagellar regulon, decreasing motility [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790783, Length=268, Percent_Identity=34.3283582089552, Blast_Score=141, Evalue=6e-35,
Organism=Escherichia coli, GI1787879, Length=267, Percent_Identity=29.5880149812734, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI145693193, Length=280, Percent_Identity=25, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35607; Mature: 35607

Theoretical pI: Translated: 7.21; Mature: 7.21

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELKWLEDFVSLAETRSFSRSAELRHVSQPAFSRRIQALEAWLATELIDRSVYPTRLTQA
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
GQIFYEQALTMLSQAHEARTLLRGHVGAPVPTIEFAVPHTLSLTYFPRWLERIEAKMGQV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCEEEHHHHHHHHHHHHHHHHHH
HTRLRALNVHDAVLSLVEGGCDLVMGYHHPSHPVALDPARYDMLILGSEPISPFSAPGRA
HHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCEEECCCCCCEEEECCCCCCCCCCCCCC
GRPRHTLPGAADARVPYLSYTPNAYLGRMTEVIIANAPTRLFLDRVYETDMAEGLKAMAL
CCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
AGHGVAFLPHSAVDDAVAGGRLIRLDRSARGGAHPFTLTMEIRLYCDKLALQGDDPRQKL
CCCCEEECCCHHHHHHHCCCEEEEEECCCCCCCCCEEEEEEEEEHHHHHHCCCCCHHHHH
VRALWDVVRDELRDTTGDAAA
HHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MELKWLEDFVSLAETRSFSRSAELRHVSQPAFSRRIQALEAWLATELIDRSVYPTRLTQA
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
GQIFYEQALTMLSQAHEARTLLRGHVGAPVPTIEFAVPHTLSLTYFPRWLERIEAKMGQV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCEEEHHHHHHHHHHHHHHHHHH
HTRLRALNVHDAVLSLVEGGCDLVMGYHHPSHPVALDPARYDMLILGSEPISPFSAPGRA
HHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCEEECCCCCCEEEECCCCCCCCCCCCCC
GRPRHTLPGAADARVPYLSYTPNAYLGRMTEVIIANAPTRLFLDRVYETDMAEGLKAMAL
CCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
AGHGVAFLPHSAVDDAVAGGRLIRLDRSARGGAHPFTLTMEIRLYCDKLALQGDDPRQKL
CCCCEEECCCHHHHHHHCCCEEEEEECCCCCCCCCEEEEEEEEEHHHHHHCCCCCHHHHH
VRALWDVVRDELRDTTGDAAA
HHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 7876157 [H]