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The map label for this gene is gntP [H]

Identifier: 116688685

GI number: 116688685

Start: 736458

End: 737819

Strand: Direct

Name: gntP [H]

Synonym: Bcen2424_0662

Alternate gene names: 116688685

Gene position: 736458-737819 (Clockwise)

Preceding gene: 116688684

Following gene: 116688686

Centisome position: 21.14

GC content: 65.27

Gene sequence:

>1362_bases
ATGGGGGCCGTCCAAGGCAGCATGCTGCTCGTATTCACGCTGATCGCGATTGCCGCGCTGATCCTGATGATCGCGCGCTA
CAAGATCTACCCGTTCCTGGTGCTGATCATCGTCTCGCTCGGCCTCGGTCTCGTCGTCGGCATGCCGATGGACAAGATCG
TCAAGTCGTTCGAGACGGGCACCGGCGGCACGCTCGGCCACATCGCGATCGTCGTCGGCCTCGGCACGATGCTCGGCAAG
ATGATGGCCGAATCGGGCGGTGCCGAACGGATCGCGACCACGCTGATCGACTGGTTCGGTGAAAAGAACATCCACTGGGC
GATGATGTTCGTCGCGATCATCGTCGGCCTGCCGGTGTTCTTCGAAGTCGGCTTCGTGCTGCTGATCCCGATCGCGTTCA
ACGTCGCGAAGCGCACCGGCAAGTCGCTGCTCGTCGTCGGCCTGCCGATGGTGGCCGGCCTGTCGGTCGTGCACGGGCTG
ATCCCGCCGCACCCGGCTGCGCTACTGGCCGTCCAGCAATACGGCGCCGATATCGGCAAGACGATCGCCTTCGGCCTGGT
CGTCGGCGTGCCGACCGCGATCATCGCGGGCCCGCTGTTCGCGCTGATGATCTCGAAGTTCGTGAAGCTGCCGGAAAACA
ACCCGCTCGCGTCGCAATTCGTCGATTCGCGCACGGACGGCGGCAAGCGCGAGCTGCCGAGCTTCGGCATCACGCTGTTC
ACGATCCTGCTGCCCGTCGTGCTGATGCTCGTCGGCAGCTGGGCCGACCTGGTGTTCACGCCGAAGTCGCTGCCGAACAA
CCTGCTGCGCTTTGCGGGCAACTCGGACGTCGCGCTGCTGATCGCCGTGCTCGTGAGCTTCTGGACCTTCGGCGCGAAGC
AGGGCTTCAACCGCGACCAGATCCAGAAGTTCTGCGGCGAGTGCCTGGCGCCGATCGCCGGGATCACGCTGATCGTCGGC
GCGGGCGGCGGCTTCGGCGGCGTCCTGCGCGACAGCGGGATTTCGCAGCAGATCGTCGAGACCGCGAAGCACGCGCACCT
GTCGCCGCTGCTGCTCGGCTGGTTCGTCGCGGCGCTGATGCGTCTCGCGACGGGTTCGGCGACGGTCGCGATGACGACGG
CCTGCGGTATCGTCGCGCCGATCGCGGCGGCGTCGGGCGCGTCGGTCCGGCCGGAACTGCTGGTGCTCGCGACGGGCTCG
GGCTCGCTGATCTTCTCGCACGTGAACGACGGTGGCTTCTGGCTGATCAAGGAATATTTCGGGATGACGGTGGGCCAGAC
GTTCAAGACCTGGTCGCTGCTTGAAACCATCATCTCGGTGCTCGGTCTGAGTTTTACGCTGTTGCTGAGCGTGGTTCTGT
AA

Upstream 100 bases:

>100_bases
GCGTCCTGACGGGGGGGTACCCCCGTGTTTCGGAGACCCGCATAGCCGGGCATACTCGCAACGACTCGCCCGGTTCGAAC
AATTCTAGGAGGAGTGCCAC

Downstream 100 bases:

>100_bases
CAAGGGGTAGTCAATGATTCTGATCGCAATGGGCGTATCGGGCGCGGGCAAGTCGCTGATCGGCGAAATGCTGGCGGAAC
GCCTGTCGTGCAGCTATACC

Product: gluconate transporter

Products: Proton [Cytoplasm]; gluconate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 453; Mature: 452

Protein sequence:

>453_residues
MGAVQGSMLLVFTLIAIAALILMIARYKIYPFLVLIIVSLGLGLVVGMPMDKIVKSFETGTGGTLGHIAIVVGLGTMLGK
MMAESGGAERIATTLIDWFGEKNIHWAMMFVAIIVGLPVFFEVGFVLLIPIAFNVAKRTGKSLLVVGLPMVAGLSVVHGL
IPPHPAALLAVQQYGADIGKTIAFGLVVGVPTAIIAGPLFALMISKFVKLPENNPLASQFVDSRTDGGKRELPSFGITLF
TILLPVVLMLVGSWADLVFTPKSLPNNLLRFAGNSDVALLIAVLVSFWTFGAKQGFNRDQIQKFCGECLAPIAGITLIVG
AGGGFGGVLRDSGISQQIVETAKHAHLSPLLLGWFVAALMRLATGSATVAMTTACGIVAPIAAASGASVRPELLVLATGS
GSLIFSHVNDGGFWLIKEYFGMTVGQTFKTWSLLETIISVLGLSFTLLLSVVL

Sequences:

>Translated_453_residues
MGAVQGSMLLVFTLIAIAALILMIARYKIYPFLVLIIVSLGLGLVVGMPMDKIVKSFETGTGGTLGHIAIVVGLGTMLGK
MMAESGGAERIATTLIDWFGEKNIHWAMMFVAIIVGLPVFFEVGFVLLIPIAFNVAKRTGKSLLVVGLPMVAGLSVVHGL
IPPHPAALLAVQQYGADIGKTIAFGLVVGVPTAIIAGPLFALMISKFVKLPENNPLASQFVDSRTDGGKRELPSFGITLF
TILLPVVLMLVGSWADLVFTPKSLPNNLLRFAGNSDVALLIAVLVSFWTFGAKQGFNRDQIQKFCGECLAPIAGITLIVG
AGGGFGGVLRDSGISQQIVETAKHAHLSPLLLGWFVAALMRLATGSATVAMTTACGIVAPIAAASGASVRPELLVLATGS
GSLIFSHVNDGGFWLIKEYFGMTVGQTFKTWSLLETIISVLGLSFTLLLSVVL
>Mature_452_residues
GAVQGSMLLVFTLIAIAALILMIARYKIYPFLVLIIVSLGLGLVVGMPMDKIVKSFETGTGGTLGHIAIVVGLGTMLGKM
MAESGGAERIATTLIDWFGEKNIHWAMMFVAIIVGLPVFFEVGFVLLIPIAFNVAKRTGKSLLVVGLPMVAGLSVVHGLI
PPHPAALLAVQQYGADIGKTIAFGLVVGVPTAIIAGPLFALMISKFVKLPENNPLASQFVDSRTDGGKRELPSFGITLFT
ILLPVVLMLVGSWADLVFTPKSLPNNLLRFAGNSDVALLIAVLVSFWTFGAKQGFNRDQIQKFCGECLAPIAGITLIVGA
GGGFGGVLRDSGISQQIVETAKHAHLSPLLLGWFVAALMRLATGSATVAMTTACGIVAPIAAASGASVRPELLVLATGSG
SLIFSHVNDGGFWLIKEYFGMTVGQTFKTWSLLETIISVLGLSFTLLLSVVL

Specific function: Part Of The Gluconate Utilization System Gnt-I; High- Affinity Intake Of Gluconate. [C]

COG id: COG2610

COG function: function code GE; H+/gluconate symporter and related permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gntP permease family [H]

Homologues:

Organism=Escherichia coli, GI48994935, Length=450, Percent_Identity=46.6666666666667, Blast_Score=373, Evalue=1e-104,
Organism=Escherichia coli, GI1790716, Length=446, Percent_Identity=40.5829596412556, Blast_Score=342, Evalue=2e-95,
Organism=Escherichia coli, GI1788707, Length=443, Percent_Identity=41.7607223476298, Blast_Score=312, Evalue=2e-86,
Organism=Escherichia coli, GI2367370, Length=428, Percent_Identity=40.6542056074766, Blast_Score=307, Evalue=1e-84,
Organism=Escherichia coli, GI1790776, Length=432, Percent_Identity=34.2592592592593, Blast_Score=259, Evalue=2e-70,
Organism=Escherichia coli, GI48994939, Length=426, Percent_Identity=37.793427230047, Blast_Score=257, Evalue=1e-69,
Organism=Escherichia coli, GI1789097, Length=446, Percent_Identity=33.6322869955157, Blast_Score=209, Evalue=4e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003474 [H]

Pfam domain/function: PF02447 GntP_permease [H]

EC number: NA

Molecular weight: Translated: 47562; Mature: 47430

Theoretical pI: Translated: 9.44; Mature: 9.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
GAVQGSMLLVFTLIAIAALILMIARYKIYPFLVLIIVSLGLGLVVGMPMDKIVKSFETG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCC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CCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; gluconate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + gluconate [Periplasm] = Proton [Cytoplasm] + gluconate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA