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The map label for this gene is exuR [H]

Identifier: 116688668

GI number: 116688668

Start: 718611

End: 719303

Strand: Reverse

Name: exuR [H]

Synonym: Bcen2424_0645

Alternate gene names: 116688668

Gene position: 719303-718611 (Counterclockwise)

Preceding gene: 116688672

Following gene: 116688666

Centisome position: 20.65

GC content: 67.97

Gene sequence:

>693_bases
ATGAAAAATGTTCCGCATACCGTGACCGACGCCGCCATCGCGACGATCCGCGACCGGATCGAGGCAGGCGTCTATCCGGT
CGGCAGCCTGCTGCCGGCCCAGCGCCAGCTCTCCGAGGAGCTGGAGATCAGCCGCGCGTCGCTGCGCGAGGCGCTGTCGA
CGCTCGAGGCGCTCGGGATGCTGCGCATCCGCGCGGGCAAGGGCGTGTACGTCGAAAGCGCGCAGGCGTCCGCCGCGCAT
CCGTGGCAATTCGCCGAGCAGTCGTCCCCGCCCGATACGTACCAGATGCGCTATGCGCTCGAAGGCTTCGCCGCGCGGAT
GGCCGCGCACGTCGTCAGCGACGAAGACATCGCGTGGTTCGAGGACAATCTCGCCGACCTGCACGTCGCGCTGACCGAAA
GCGCGCTCGACGAAGCATCGCGGCTCGACTTCGACTTCCACATGCGGATCATTCATCTGGCCGGCAACGCGGCGATCGAA
TCCATCCTGCGCAGCAGCGCGGACATCATGAAGGAAAGCCAGCGCATGCCGTTCTACCGGCGCGAGCTGCTGCTGTCGAC
GTGGCACGAGCACCGCGCGATCGTCGACGCGCTGATCGCGCGCGATGCGGCAGCCGCCGGCACCGCGATCGAAACGCACA
TCACGAACGCGGCGCAGCGCGCGGGCGTCTTCTTCCCGACGCCCGGCGCGTAA

Upstream 100 bases:

>100_bases
CGCGCCCCGCAAAGGGGCGGATCGTGGCTTTCCCGTAGGGTGGTCATGCACCGCCCGCGTGCGGATTACAATGCCGGTCA
GACCGGCCATCGTTCACATC

Downstream 100 bases:

>100_bases
TCCTCCCGCGCCGCGGCCCGGCCTTCCGCCCGGCCGTGCCGGTCACCGTTCCGACGGATCGCGATATGCGAGCACGCGCT
CGATGAATGCGCGCGCCGCG

Product: GntR domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MKNVPHTVTDAAIATIRDRIEAGVYPVGSLLPAQRQLSEELEISRASLREALSTLEALGMLRIRAGKGVYVESAQASAAH
PWQFAEQSSPPDTYQMRYALEGFAARMAAHVVSDEDIAWFEDNLADLHVALTESALDEASRLDFDFHMRIIHLAGNAAIE
SILRSSADIMKESQRMPFYRRELLLSTWHEHRAIVDALIARDAAAAGTAIETHITNAAQRAGVFFPTPGA

Sequences:

>Translated_230_residues
MKNVPHTVTDAAIATIRDRIEAGVYPVGSLLPAQRQLSEELEISRASLREALSTLEALGMLRIRAGKGVYVESAQASAAH
PWQFAEQSSPPDTYQMRYALEGFAARMAAHVVSDEDIAWFEDNLADLHVALTESALDEASRLDFDFHMRIIHLAGNAAIE
SILRSSADIMKESQRMPFYRRELLLSTWHEHRAIVDALIARDAAAAGTAIETHITNAAQRAGVFFPTPGA
>Mature_230_residues
MKNVPHTVTDAAIATIRDRIEAGVYPVGSLLPAQRQLSEELEISRASLREALSTLEALGMLRIRAGKGVYVESAQASAAH
PWQFAEQSSPPDTYQMRYALEGFAARMAAHVVSDEDIAWFEDNLADLHVALTESALDEASRLDFDFHMRIIHLAGNAAIE
SILRSSADIMKESQRMPFYRRELLLSTWHEHRAIVDALIARDAAAAGTAIETHITNAAQRAGVFFPTPGA

Specific function: Repressor for the exu regulon that encode genes involved in hexuronate utilization. It regulates the exuT, uxaCA and uxuRAB operons. Binds D-tagaturonate and D-fructuronate as inducers [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790780, Length=220, Percent_Identity=30.9090909090909, Blast_Score=84, Evalue=7e-18,
Organism=Escherichia coli, GI87082208, Length=227, Percent_Identity=29.0748898678414, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI1786303, Length=200, Percent_Identity=30, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1790032, Length=224, Percent_Identity=27.2321428571429, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1789353, Length=181, Percent_Identity=29.8342541436464, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 25265; Mature: 25265

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNVPHTVTDAAIATIRDRIEAGVYPVGSLLPAQRQLSEELEISRASLREALSTLEALGM
CCCCCCHHHHHHHHHHHHHHHCCCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRIRAGKGVYVESAQASAAHPWQFAEQSSPPDTYQMRYALEGFAARMAAHVVSDEDIAWF
HHEECCCCEEEECCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHH
EDNLADLHVALTESALDEASRLDFDFHMRIIHLAGNAAIESILRSSADIMKESQRMPFYR
HCCHHHHHHHHHHHHHHHHHHCCHHHHEEEEEECCHHHHHHHHHHHHHHHHHHHCCCHHH
RELLLSTWHEHRAIVDALIARDAAAAGTAIETHITNAAQRAGVFFPTPGA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MKNVPHTVTDAAIATIRDRIEAGVYPVGSLLPAQRQLSEELEISRASLREALSTLEALGM
CCCCCCHHHHHHHHHHHHHHHCCCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRIRAGKGVYVESAQASAAHPWQFAEQSSPPDTYQMRYALEGFAARMAAHVVSDEDIAWF
HHEECCCCEEEECCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHH
EDNLADLHVALTESALDEASRLDFDFHMRIIHLAGNAAIESILRSSADIMKESQRMPFYR
HCCHHHHHHHHHHHHHHHHHHCCHHHHEEEEEECCHHHHHHHHHHHHHHHHHHHCCCHHH
RELLLSTWHEHRAIVDALIARDAAAAGTAIETHITNAAQRAGVFFPTPGA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA