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The map label for this gene is tkt1 [H]

Identifier: 116688661

GI number: 116688661

Start: 709890

End: 711962

Strand: Direct

Name: tkt1 [H]

Synonym: Bcen2424_0638

Alternate gene names: 116688661

Gene position: 709890-711962 (Clockwise)

Preceding gene: 116688657

Following gene: 116688662

Centisome position: 20.38

GC content: 67.25

Gene sequence:

>2073_bases
ATGCCGCCGTGCCCCCGTTTCCTCGACTCGTTCTCCGGACTCGACATGACGACTTCGTCTCCCGCCTCCACCACCCTGAT
GGCCAACGCGATCCGTGCGCTCGCGATGGACGCCGTCCAGCAAGCGAACTCCGGCCACCCCGGCATGCCGATGGGCATGG
CCGAAATCGGCGTCGCACTCTGGTCGCGCCATCTGAAGCACAACCCGACGAACCCGCACTGGGCCGATCGCGACCGTTTC
GTGCTGTCGAACGGCCATGGCTCGATGCTGCTGTACTCGCTGCTGCATCTGACCGGCTACGACCTGCCGATCGAAGAGCT
GAAGAATTTCCGCCAGCTGCACTCGAAGACGCCGGGCCACCCCGAATACGGGATCACGCCGGGCGTCGAGACGACCACCG
GCCCGCTCGGCCAGGGTCTCGCGAACGCGGTCGGCATGGCGCTCGGCGAAGCGCTGATGGCCGACGAGTTCAACCGTGAC
GGCGCGAAGATCGTCGATCACCACACGTACGTGTTCCTCGGCGACGGCTGCCTGATGGAAGGCATCTCGCACGAAGCCTG
CTCGCTCGCGGGCACGCTGAAGCTGAACAAGCTGATCGCGCTGTACGACGACAACGGCATCTCGATCGACGGCGACGTCG
TGAACTGGTTCCACGACGACACGCCGAAGCGCTTCGAAGCGTACGGCTGGAACGTGATCCCGAACGTGAACGGCCACGAC
GTCGACGCGGTCGACGCGGCCATCGCGAAGGCGAAGCTGTCGGACAAACCGACGCTGATCTGCTGCAAGACGGTGATCGG
CAAGGGCGCGGCCACGAAGGCCGGCGGCCACGACGTGCACGGCGCGGCGCTCGGCGCGGAAGAAATCGCGAAGACGCGCG
AAGCGCTCGGCTGGAAGTGGGAGCCGTTCGTGATTCCGCAGGAAGTCTATGCGGCCTGGGATGCGAAGGAAGCCGGCAAG
CGTGCCGAGTCGGAGTGGGACGCGACGTTCGCCGCGTATCGCGCGAAGTTCCCGGCGGAAGCCGCCGAATTCGAGCGCCG
GATGGCCAACAAGCTGCCGGCCGACTGGGCCGAGAAGGCTGCGGCGATCATCGCCGGCGCGAACGAGCGCGCCGAGACGG
TCGCGACCCGCAAGGCGTCGCAGCAGGCGATCGAGGGCCTCGCCGCCGCGCTGCCGGAGCTGCTCGGCGGCTCGGCCGAC
CTGACCGGCTCGAACCTGACCAACTGGAAGGCGTCGAAGGCGGTCCGCGCGAATCCGGAAGGCGCGGGCGTGCTGCTCGG
CAACCACATCAACTACGGCGTGCGCGAATTCGGCATGAGCGCGGCGATCAACGGTCTCGCGCTGCACGGCGGCCACAAGC
CGTTCGGCGGCACGTTCCTGACGTTCTCCGACTACAGCCGCAACGCGCTGCGCGTGGCCGCGCTGATGAAGGTGCCGTCG
ATCTTCGTGTTCACGCACGATTCGATCGGCCTCGGCGAAGACGGCCCGACGCACCAGTCGATCGAGCACGTGTCGAGCCT
GCGCCTGATCCCGAACCACGACGTGTGGCGTCCGGCCGACACGGTCGAGACGGCCGTCGCGTGGACCCACGCGGTCGCTG
CCGACCGTCCGTCGAGTCTGATCTTCAGCCGCCAGAACCTCGCGTTCAACCCGCGTACCGATGCGCAGATCGCCAACATC
GAGAAGGGCGGTTACGTGCTGAAGGACTGGGACGAGGAAATCGTCGCACGCAAGATCATCCTGATCGCGACGGGCTCGGA
AGTCGAACTCGCGATGAAGGCCGTCGAGCCGCTCGCGCAGCAGGGCATCGCGGCGCGCGTCGTGTCGATGCCGTCGACCA
ACGTGTTCGACCGCCAGGACGCCGAATATCGCGAACGCGTGCTGCCGCACGGCGTGCGCCGCGTCGCGATCGAAGCGGGC
GTGACGAGCTTCTGGCACAAGTACGTCGGCCTCGAAGGCGGCGTCGTCGGGATCGACACGTTCGGCGAGTCGGCGCCGGC
CGGCGTGCTGTTCAAGTACTTCGGCTTCACCGTCGAGCACGTCGTCGAGACGGCCAAGGCCGTGCTGGCCTAA

Upstream 100 bases:

>100_bases
AAAATGACGAGCTTTGCAGCCCCGTCCGTTGGCTCCGTCCGCTTCGCGTCCGTCAGGCGCCGCACCGCGCGCCGGGAACG
ATTGACGCTCGAGCTTCCGG

Downstream 100 bases:

>100_bases
ATAAAAGCATACGCGGCGCGCGCCACCCGTTGCGCGCGTCGCACCGTGAAGCTGCACGAAACGAATTTTTTCAGCCATCA
GGAGATAGACCATGACGATT

Product: transketolase

Products: NA

Alternate protein names: TK 1 [H]

Number of amino acids: Translated: 690; Mature: 689

Protein sequence:

>690_residues
MPPCPRFLDSFSGLDMTTSSPASTTLMANAIRALAMDAVQQANSGHPGMPMGMAEIGVALWSRHLKHNPTNPHWADRDRF
VLSNGHGSMLLYSLLHLTGYDLPIEELKNFRQLHSKTPGHPEYGITPGVETTTGPLGQGLANAVGMALGEALMADEFNRD
GAKIVDHHTYVFLGDGCLMEGISHEACSLAGTLKLNKLIALYDDNGISIDGDVVNWFHDDTPKRFEAYGWNVIPNVNGHD
VDAVDAAIAKAKLSDKPTLICCKTVIGKGAATKAGGHDVHGAALGAEEIAKTREALGWKWEPFVIPQEVYAAWDAKEAGK
RAESEWDATFAAYRAKFPAEAAEFERRMANKLPADWAEKAAAIIAGANERAETVATRKASQQAIEGLAAALPELLGGSAD
LTGSNLTNWKASKAVRANPEGAGVLLGNHINYGVREFGMSAAINGLALHGGHKPFGGTFLTFSDYSRNALRVAALMKVPS
IFVFTHDSIGLGEDGPTHQSIEHVSSLRLIPNHDVWRPADTVETAVAWTHAVAADRPSSLIFSRQNLAFNPRTDAQIANI
EKGGYVLKDWDEEIVARKIILIATGSEVELAMKAVEPLAQQGIAARVVSMPSTNVFDRQDAEYRERVLPHGVRRVAIEAG
VTSFWHKYVGLEGGVVGIDTFGESAPAGVLFKYFGFTVEHVVETAKAVLA

Sequences:

>Translated_690_residues
MPPCPRFLDSFSGLDMTTSSPASTTLMANAIRALAMDAVQQANSGHPGMPMGMAEIGVALWSRHLKHNPTNPHWADRDRF
VLSNGHGSMLLYSLLHLTGYDLPIEELKNFRQLHSKTPGHPEYGITPGVETTTGPLGQGLANAVGMALGEALMADEFNRD
GAKIVDHHTYVFLGDGCLMEGISHEACSLAGTLKLNKLIALYDDNGISIDGDVVNWFHDDTPKRFEAYGWNVIPNVNGHD
VDAVDAAIAKAKLSDKPTLICCKTVIGKGAATKAGGHDVHGAALGAEEIAKTREALGWKWEPFVIPQEVYAAWDAKEAGK
RAESEWDATFAAYRAKFPAEAAEFERRMANKLPADWAEKAAAIIAGANERAETVATRKASQQAIEGLAAALPELLGGSAD
LTGSNLTNWKASKAVRANPEGAGVLLGNHINYGVREFGMSAAINGLALHGGHKPFGGTFLTFSDYSRNALRVAALMKVPS
IFVFTHDSIGLGEDGPTHQSIEHVSSLRLIPNHDVWRPADTVETAVAWTHAVAADRPSSLIFSRQNLAFNPRTDAQIANI
EKGGYVLKDWDEEIVARKIILIATGSEVELAMKAVEPLAQQGIAARVVSMPSTNVFDRQDAEYRERVLPHGVRRVAIEAG
VTSFWHKYVGLEGGVVGIDTFGESAPAGVLFKYFGFTVEHVVETAKAVLA
>Mature_689_residues
PPCPRFLDSFSGLDMTTSSPASTTLMANAIRALAMDAVQQANSGHPGMPMGMAEIGVALWSRHLKHNPTNPHWADRDRFV
LSNGHGSMLLYSLLHLTGYDLPIEELKNFRQLHSKTPGHPEYGITPGVETTTGPLGQGLANAVGMALGEALMADEFNRDG
AKIVDHHTYVFLGDGCLMEGISHEACSLAGTLKLNKLIALYDDNGISIDGDVVNWFHDDTPKRFEAYGWNVIPNVNGHDV
DAVDAAIAKAKLSDKPTLICCKTVIGKGAATKAGGHDVHGAALGAEEIAKTREALGWKWEPFVIPQEVYAAWDAKEAGKR
AESEWDATFAAYRAKFPAEAAEFERRMANKLPADWAEKAAAIIAGANERAETVATRKASQQAIEGLAAALPELLGGSADL
TGSNLTNWKASKAVRANPEGAGVLLGNHINYGVREFGMSAAINGLALHGGHKPFGGTFLTFSDYSRNALRVAALMKVPSI
FVFTHDSIGLGEDGPTHQSIEHVSSLRLIPNHDVWRPADTVETAVAWTHAVAADRPSSLIFSRQNLAFNPRTDAQIANIE
KGGYVLKDWDEEIVARKIILIATGSEVELAMKAVEPLAQQGIAARVVSMPSTNVFDRQDAEYRERVLPHGVRRVAIEAGV
TSFWHKYVGLEGGVVGIDTFGESAPAGVLFKYFGFTVEHVVETAKAVLA

Specific function: Unknown

COG id: COG0021

COG function: function code G; Transketolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=607, Percent_Identity=27.6771004942339, Blast_Score=161, Evalue=2e-39,
Organism=Homo sapiens, GI4507521, Length=607, Percent_Identity=27.6771004942339, Blast_Score=161, Evalue=2e-39,
Organism=Homo sapiens, GI133778974, Length=589, Percent_Identity=26.8251273344652, Blast_Score=137, Evalue=3e-32,
Organism=Escherichia coli, GI48994911, Length=671, Percent_Identity=63.3383010432191, Blast_Score=867, Evalue=0.0,
Organism=Escherichia coli, GI1788808, Length=666, Percent_Identity=60.5105105105105, Blast_Score=812, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17539652, Length=682, Percent_Identity=26.5395894428152, Blast_Score=162, Evalue=4e-40,
Organism=Saccharomyces cerevisiae, GI6325331, Length=673, Percent_Identity=49.777117384844, Blast_Score=613, Evalue=1e-176,
Organism=Saccharomyces cerevisiae, GI6319593, Length=675, Percent_Identity=45.6296296296296, Blast_Score=559, Evalue=1e-160,
Organism=Drosophila melanogaster, GI45551847, Length=716, Percent_Identity=25.2793296089385, Blast_Score=160, Evalue=4e-39,
Organism=Drosophila melanogaster, GI45550715, Length=716, Percent_Identity=25.2793296089385, Blast_Score=160, Evalue=4e-39,
Organism=Drosophila melanogaster, GI24666278, Length=675, Percent_Identity=25.4814814814815, Blast_Score=147, Evalue=2e-35,
Organism=Drosophila melanogaster, GI24645119, Length=667, Percent_Identity=25.0374812593703, Blast_Score=140, Evalue=4e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005478
- InterPro:   IPR020826
- InterPro:   IPR005476
- InterPro:   IPR005474 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C; PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 74201; Mature: 74069

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: PS00801 TRANSKETOLASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPCPRFLDSFSGLDMTTSSPASTTLMANAIRALAMDAVQQANSGHPGMPMGMAEIGVAL
CCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
WSRHLKHNPTNPHWADRDRFVLSNGHGSMLLYSLLHLTGYDLPIEELKNFRQLHSKTPGH
HHHHHCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCC
PEYGITPGVETTTGPLGQGLANAVGMALGEALMADEFNRDGAKIVDHHTYVFLGDGCLME
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCEEEEECCCHHHH
GISHEACSLAGTLKLNKLIALYDDNGISIDGDVVNWFHDDTPKRFEAYGWNVIPNVNGHD
CCCHHHHHHHHHEEEEEEEEEECCCCCEECCCEEECCCCCCCCHHHHCCCEECCCCCCCC
VDAVDAAIAKAKLSDKPTLICCKTVIGKGAATKAGGHDVHGAALGAEEIAKTREALGWKW
CHHHHHHHHHHHCCCCCCEEEEHHHHCCCCCCCCCCCCCCHHHCCHHHHHHHHHHHCCCC
EPFVIPQEVYAAWDAKEAGKRAESEWDATFAAYRAKFPAEAAEFERRMANKLPADWAEKA
CCEECHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHH
AAIIAGANERAETVATRKASQQAIEGLAAALPELLGGSADLTGSNLTNWKASKAVRANPE
HEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEECCCC
GAGVLLGNHINYGVREFGMSAAINGLALHGGHKPFGGTFLTFSDYSRNALRVAALMKVPS
CCEEEEECCCCCCHHHHHHHHHHCCEEEECCCCCCCCEEEEECCCCCCHHHHHHHHHCCE
IFVFTHDSIGLGEDGPTHQSIEHVSSLRLIPNHDVWRPADTVETAVAWTHAVAADRPSSL
EEEEECCCCCCCCCCCCHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCHH
IFSRQNLAFNPRTDAQIANIEKGGYVLKDWDEEIVARKIILIATGSEVELAMKAVEPLAQ
EEECCCCCCCCCCCCEEEEECCCCEEEECCHHHHHHCEEEEEEECCHHHHHHHHHHHHHH
QGIAARVVSMPSTNVFDRQDAEYRERVLPHGVRRVAIEAGVTSFWHKYVGLEGGVVGIDT
CCHHEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEC
FGESAPAGVLFKYFGFTVEHVVETAKAVLA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PPCPRFLDSFSGLDMTTSSPASTTLMANAIRALAMDAVQQANSGHPGMPMGMAEIGVAL
CCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
WSRHLKHNPTNPHWADRDRFVLSNGHGSMLLYSLLHLTGYDLPIEELKNFRQLHSKTPGH
HHHHHCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCC
PEYGITPGVETTTGPLGQGLANAVGMALGEALMADEFNRDGAKIVDHHTYVFLGDGCLME
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCEEEEECCCHHHH
GISHEACSLAGTLKLNKLIALYDDNGISIDGDVVNWFHDDTPKRFEAYGWNVIPNVNGHD
CCCHHHHHHHHHEEEEEEEEEECCCCCEECCCEEECCCCCCCCHHHHCCCEECCCCCCCC
VDAVDAAIAKAKLSDKPTLICCKTVIGKGAATKAGGHDVHGAALGAEEIAKTREALGWKW
CHHHHHHHHHHHCCCCCCEEEEHHHHCCCCCCCCCCCCCCHHHCCHHHHHHHHHHHCCCC
EPFVIPQEVYAAWDAKEAGKRAESEWDATFAAYRAKFPAEAAEFERRMANKLPADWAEKA
CCEECHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHH
AAIIAGANERAETVATRKASQQAIEGLAAALPELLGGSADLTGSNLTNWKASKAVRANPE
HEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEECCCC
GAGVLLGNHINYGVREFGMSAAINGLALHGGHKPFGGTFLTFSDYSRNALRVAALMKVPS
CCEEEEECCCCCCHHHHHHHHHHCCEEEECCCCCCCCEEEEECCCCCCHHHHHHHHHCCE
IFVFTHDSIGLGEDGPTHQSIEHVSSLRLIPNHDVWRPADTVETAVAWTHAVAADRPSSL
EEEEECCCCCCCCCCCCHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCHH
IFSRQNLAFNPRTDAQIANIEKGGYVLKDWDEEIVARKIILIATGSEVELAMKAVEPLAQ
EEECCCCCCCCCCCCEEEEECCCCEEEECCHHHHHHCEEEEEEECCHHHHHHHHHHHHHH
QGIAARVVSMPSTNVFDRQDAEYRERVLPHGVRRVAIEAGVTSFWHKYVGLEGGVVGIDT
CCHHEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEC
FGESAPAGVLFKYFGFTVEHVVETAKAVLA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA