| Definition | Burkholderia cenocepacia HI2424 chromosome 1, complete sequence. |
|---|---|
| Accession | NC_008542 |
| Length | 3,483,902 |
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The map label for this gene is murC [H]
Identifier: 116688584
GI number: 116688584
Start: 630459
End: 631856
Strand: Direct
Name: murC [H]
Synonym: Bcen2424_0560
Alternate gene names: 116688584
Gene position: 630459-631856 (Clockwise)
Preceding gene: 116688583
Following gene: 116688585
Centisome position: 18.1
GC content: 68.88
Gene sequence:
>1398_bases ATGAAACACATCGTCAAACACATTCATTTCGTCGGGATCGGCGGCGCGGGCATGAGCGGCATCGCCGAAGTGCTCGTCAA CCTCGGCTACGCGGTCAGCGGCTCGGACCTGTCGCGCAATGCGGTGACCGATCGCCTCGAGGCGCTAGGCGCGCGGATCG CGATCGGCCACGACGCGGCGAACATCGAGGGCGCGAACGCGGTCGTCGTGTCGACGGCCGTGCGCTCGGACAACCCGGAA GTGCTGGCCGCGCGCCACCAGGGCGTGCCGATCGTGCAGCGCGCGGTGATGCTGGCGGAGCTGATGCGCCTGAAGCAGGG CATCGCGATCGCCGGCACGCACGGCAAGACCACGACGACGAGCCTCGTCGCGAGCGTGCTCGCCGCGGGCGGGCTGGACC CGACCTTCGTGATCGGCGGCCGGCTGATCAGCGCCGGCGCGAACGCGCGGCTCGGCACGGGCGACTTCATCGTCGCCGAG GCCGACGAGTCGGATGCGTCGTTCCTGAACCTGTACCCGGTGATCGAAGTCATCACGAACATCGACGCCGACCACATGGA CACCTACGGCCACGATTTCGCGCGGCTCAAGCAGGCGTTCATCGAATTCACGCAGCGCCTGCCGTTCTACGGCAGCGCGG TGGTGTGCGTCGACGATCCGAACGTGCGGCAGATCATTCCGTTCATCTCGAAGCCGGTCGTGCGCTACGGCCTGTCGCCG GACGCGCAGGTGCGCGCGGAAGACATCGACGCGCGCGACGGCCGGATGCACTTCACGGTGATCCGCGAAGGGCGTGCGCC GCTCGCGGTCGTGCTGAACATGCCGGGCCTGCACAACGTGCAGAACGCGCTCGCGGCGATCGCGATCGCAACCGATCTCG GCGTGTCGGACGACGCGATCCAGCTGGCGCTGGCGGAATTCAACGGCGTCGGCCGGCGCTTCCAGCGCTACGGCGAGGTG CCGAGCGCGGACGGCGGCCAGTACACGCTGATCGACGACTACGGTCATCACCCGGTCGAGATGGCGGCGACGATCGCGGC CGCGCGCGGCGCGTTCCCGGGCCGTCGCCTCGTGCTGGCGTTCCAGCCGCACCGCTACACGCGCACGCGCGACTGCTTCG ACGATTTCGTCAACGTGCTGTCGACGGTCGATGCGCTGGTGCTGACGGAAGTCTATGCGGCCGGCGAGGCCGCGATCCCG ACGGCCAGCGGCGACGCGCTGTCGCGTGCGCTGCGCGCGGTGGGCAAGGTCGACCCGGTGTTCGTCGCGACGGTCGACGA CGTGCCGGACGCATTGGCGAAGGTCGCGCAGAACGGCGACGTGGTGATCACGATGGGGGCGGGTTCGATCGGCGGCGTGC CGGCGAAGCTCGTGCAACACATTCAACAGAAGGCATGA
Upstream 100 bases:
>100_bases ACATGGCGGAACGTTCGCGCGCGCTCGCGAAGCCCGAGGCCACCGACGAAGTCGCGCGCGTCTGCGCGAAGGCGGCCGGC GCGAACCTGGAAACACTGCA
Downstream 100 bases:
>100_bases CATGAGCGGGATCGATCCGAAACGTTTCGGCAAGGTGGCGGTGTTGTTCGGCGGCGAATCCGCCGAGCGCGAGGTGTCGC TCACCTCGGGCCGCCTCGTG
Product: UDP-N-acetylmuramate--L-alanine ligase
Products: NA
Alternate protein names: UDP-N-acetylmuramoyl-L-alanine synthetase [H]
Number of amino acids: Translated: 465; Mature: 465
Protein sequence:
>465_residues MKHIVKHIHFVGIGGAGMSGIAEVLVNLGYAVSGSDLSRNAVTDRLEALGARIAIGHDAANIEGANAVVVSTAVRSDNPE VLAARHQGVPIVQRAVMLAELMRLKQGIAIAGTHGKTTTTSLVASVLAAGGLDPTFVIGGRLISAGANARLGTGDFIVAE ADESDASFLNLYPVIEVITNIDADHMDTYGHDFARLKQAFIEFTQRLPFYGSAVVCVDDPNVRQIIPFISKPVVRYGLSP DAQVRAEDIDARDGRMHFTVIREGRAPLAVVLNMPGLHNVQNALAAIAIATDLGVSDDAIQLALAEFNGVGRRFQRYGEV PSADGGQYTLIDDYGHHPVEMAATIAAARGAFPGRRLVLAFQPHRYTRTRDCFDDFVNVLSTVDALVLTEVYAAGEAAIP TASGDALSRALRAVGKVDPVFVATVDDVPDALAKVAQNGDVVITMGAGSIGGVPAKLVQHIQQKA
Sequences:
>Translated_465_residues MKHIVKHIHFVGIGGAGMSGIAEVLVNLGYAVSGSDLSRNAVTDRLEALGARIAIGHDAANIEGANAVVVSTAVRSDNPE VLAARHQGVPIVQRAVMLAELMRLKQGIAIAGTHGKTTTTSLVASVLAAGGLDPTFVIGGRLISAGANARLGTGDFIVAE ADESDASFLNLYPVIEVITNIDADHMDTYGHDFARLKQAFIEFTQRLPFYGSAVVCVDDPNVRQIIPFISKPVVRYGLSP DAQVRAEDIDARDGRMHFTVIREGRAPLAVVLNMPGLHNVQNALAAIAIATDLGVSDDAIQLALAEFNGVGRRFQRYGEV PSADGGQYTLIDDYGHHPVEMAATIAAARGAFPGRRLVLAFQPHRYTRTRDCFDDFVNVLSTVDALVLTEVYAAGEAAIP TASGDALSRALRAVGKVDPVFVATVDDVPDALAKVAQNGDVVITMGAGSIGGVPAKLVQHIQQKA >Mature_465_residues MKHIVKHIHFVGIGGAGMSGIAEVLVNLGYAVSGSDLSRNAVTDRLEALGARIAIGHDAANIEGANAVVVSTAVRSDNPE VLAARHQGVPIVQRAVMLAELMRLKQGIAIAGTHGKTTTTSLVASVLAAGGLDPTFVIGGRLISAGANARLGTGDFIVAE ADESDASFLNLYPVIEVITNIDADHMDTYGHDFARLKQAFIEFTQRLPFYGSAVVCVDDPNVRQIIPFISKPVVRYGLSP DAQVRAEDIDARDGRMHFTVIREGRAPLAVVLNMPGLHNVQNALAAIAIATDLGVSDDAIQLALAEFNGVGRRFQRYGEV PSADGGQYTLIDDYGHHPVEMAATIAAARGAFPGRRLVLAFQPHRYTRTRDCFDDFVNVLSTVDALVLTEVYAAGEAAIP TASGDALSRALRAVGKVDPVFVATVDDVPDALAKVAQNGDVVITMGAGSIGGVPAKLVQHIQQKA
Specific function: Cell wall formation [H]
COG id: COG0773
COG function: function code M; UDP-N-acetylmuramate-alanine ligase
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the MurCDEF family [H]
Homologues:
Organism=Escherichia coli, GI1786279, Length=459, Percent_Identity=53.8126361655773, Blast_Score=452, Evalue=1e-128, Organism=Escherichia coli, GI1790680, Length=474, Percent_Identity=30.5907172995781, Blast_Score=177, Evalue=1e-45,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR004101 - InterPro: IPR013221 - InterPro: IPR000713 - InterPro: IPR016040 - InterPro: IPR005758 [H]
Pfam domain/function: PF01225 Mur_ligase; PF02875 Mur_ligase_C; PF08245 Mur_ligase_M [H]
EC number: =6.3.2.8 [H]
Molecular weight: Translated: 49003; Mature: 49003
Theoretical pI: Translated: 6.01; Mature: 6.01
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 1.9 %Met (Translated Protein) 2.4 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 1.9 %Met (Mature Protein) 2.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKHIVKHIHFVGIGGAGMSGIAEVLVNLGYAVSGSDLSRNAVTDRLEALGARIAIGHDAA CCCHHHHEEEEEECCCCHHHHHHHHHHCCCEECCCCCCHHHHHHHHHHCCCEEEECCCCC NIEGANAVVVSTAVRSDNPEVLAARHQGVPIVQRAVMLAELMRLKQGIAIAGTHGKTTTT CCCCCCEEEEEEEECCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCHHH SLVASVLAAGGLDPTFVIGGRLISAGANARLGTGDFIVAEADESDASFLNLYPVIEVITN HHHHHHHHHCCCCCEEEECCEEEECCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHC IDADHMDTYGHDFARLKQAFIEFTQRLPFYGSAVVCVDDPNVRQIIPFISKPVVRYGLSP CCCHHHHHCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHCHHHHHCCCC DAQVRAEDIDARDGRMHFTVIREGRAPLAVVLNMPGLHNVQNALAAIAIATDLGVSDDAI CCCEECCCCCCCCCEEEEEEEECCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCCHHH QLALAEFNGVGRRFQRYGEVPSADGGQYTLIDDYGHHPVEMAATIAAARGAFPGRRLVLA HHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCEEEEE FQPHRYTRTRDCFDDFVNVLSTVDALVLTEVYAAGEAAIPTASGDALSRALRAVGKVDPV ECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCE FVATVDDVPDALAKVAQNGDVVITMGAGSIGGVPAKLVQHIQQKA EEEECCHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHCC >Mature Secondary Structure MKHIVKHIHFVGIGGAGMSGIAEVLVNLGYAVSGSDLSRNAVTDRLEALGARIAIGHDAA CCCHHHHEEEEEECCCCHHHHHHHHHHCCCEECCCCCCHHHHHHHHHHCCCEEEECCCCC NIEGANAVVVSTAVRSDNPEVLAARHQGVPIVQRAVMLAELMRLKQGIAIAGTHGKTTTT CCCCCCEEEEEEEECCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCHHH SLVASVLAAGGLDPTFVIGGRLISAGANARLGTGDFIVAEADESDASFLNLYPVIEVITN HHHHHHHHHCCCCCEEEECCEEEECCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHC IDADHMDTYGHDFARLKQAFIEFTQRLPFYGSAVVCVDDPNVRQIIPFISKPVVRYGLSP CCCHHHHHCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHCHHHHHCCCC DAQVRAEDIDARDGRMHFTVIREGRAPLAVVLNMPGLHNVQNALAAIAIATDLGVSDDAI CCCEECCCCCCCCCEEEEEEEECCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCCHHH QLALAEFNGVGRRFQRYGEVPSADGGQYTLIDDYGHHPVEMAATIAAARGAFPGRRLVLA HHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCEEEEE FQPHRYTRTRDCFDDFVNVLSTVDALVLTEVYAAGEAAIPTASGDALSRALRAVGKVDPV ECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCE FVATVDDVPDALAKVAQNGDVVITMGAGSIGGVPAKLVQHIQQKA EEEECCHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA