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The map label for this gene is murG [H]

Identifier: 116688583

GI number: 116688583

Start: 629359

End: 630462

Strand: Direct

Name: murG [H]

Synonym: Bcen2424_0559

Alternate gene names: 116688583

Gene position: 629359-630462 (Clockwise)

Preceding gene: 116688582

Following gene: 116688584

Centisome position: 18.06

GC content: 71.11

Gene sequence:

>1104_bases
ATGACCGCGTCGCAACGCACGCTGATGGTGATGGCAGGCGGCACCGGGGGCCACGTGTTCCCGGGGCTCGCGGTCGCGCA
CCGGATGGAAGCGGCGGGCTGGCGCGTCGTATGGCTCGGCAATCCGGCCGGGATGGAAGCGACGCTGGTGCCGAAGCACG
GCATTCCGATGGAGTACGTGCGGTTCGGCGGGCTGCGCGGCAAAGGGCTGAAGACCAAGCTGACGCTGCCGGTCAACCTG
CTGCGCGCATGCTGGCAGAGCCTCGGCGCGCTGCGCCGCGTGCGGCCGGACGTCGTGCTCGGGATGGGCGGCTACATCAC
GTTCCCGGCGGGCGTGATGACCGCGCTGTCGGGGCGTCCGCTCGTGCTGCATGAACAGAATTCGATCGCGGGCCTGACCA
ACAAGGTGCTCGCGAAACTCGCGAAGCGCGTGCTCGTCGCGTTCCCCGGCGCGCTGCCGCACGCGGAATGGACGGGTAAT
CCGATTCGCGCGGAACTGGCGCACACGGAACCGCCCCACGCACGCTATGCGTCGCGCAGCGGCCCGTTGAACGTGCTGGT
CGTCGGCGGCAGCCTCGGGGCGGCCGCGCTGAACGAAGTCGTGCCGCGCGCGCTGGCACTGCTGGCGCCGGGCGAGCGCC
CGCGCGTCGTGCACCAGGCCGGCGTGAAGCACATCGAGGCACTGAAGGCGAATTACGAAGCGGCCGGTTTCGCGGCCGGC
GAGGACGTGCGGCTCGTACCGTTCATCGACGACATGGCGGCCGCGTATGCGGCGGCGGATCTGGTGATCTGCCGGTCGGG
CGCGATGACGGTGTCGGAGATCGCGGCGGTGGGTGTGGCGGCGCTGTTCGTGCCGTTCCCGTACGCGGTCGACGATCACC
AGACGACCAACGCCGCGTTCCTCGCCGAGGCGGGCGCGGCCGTGCTGGTGCAACAACGCGACCTGTCGGCGGAGCTGCTC
GCCGACTGGCTGCGCGGCCAGTCGCGGGCGTCGCTCGCGGACATGGCGGAACGTTCGCGCGCGCTCGCGAAGCCCGAGGC
CACCGACGAAGTCGCGCGCGTCTGCGCGAAGGCGGCCGGCGCGAACCTGGAAACACTGCAATGA

Upstream 100 bases:

>100_bases
TGAGCTATGGCGGCTCCGGCATCCTGCTGAACTGTGTCGCGCTCGCGGTGCTGCTGCGGGTCGACTACGAGAACCGGGTG
CTGATGCGCGGAGGGAAGGT

Downstream 100 bases:

>100_bases
AACACATCGTCAAACACATTCATTTCGTCGGGATCGGCGGCGCGGGCATGAGCGGCATCGCCGAAGTGCTCGTCAACCTC
GGCTACGCGGTCAGCGGCTC

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase [H]

Number of amino acids: Translated: 367; Mature: 366

Protein sequence:

>367_residues
MTASQRTLMVMAGGTGGHVFPGLAVAHRMEAAGWRVVWLGNPAGMEATLVPKHGIPMEYVRFGGLRGKGLKTKLTLPVNL
LRACWQSLGALRRVRPDVVLGMGGYITFPAGVMTALSGRPLVLHEQNSIAGLTNKVLAKLAKRVLVAFPGALPHAEWTGN
PIRAELAHTEPPHARYASRSGPLNVLVVGGSLGAAALNEVVPRALALLAPGERPRVVHQAGVKHIEALKANYEAAGFAAG
EDVRLVPFIDDMAAAYAAADLVICRSGAMTVSEIAAVGVAALFVPFPYAVDDHQTTNAAFLAEAGAAVLVQQRDLSAELL
ADWLRGQSRASLADMAERSRALAKPEATDEVARVCAKAAGANLETLQ

Sequences:

>Translated_367_residues
MTASQRTLMVMAGGTGGHVFPGLAVAHRMEAAGWRVVWLGNPAGMEATLVPKHGIPMEYVRFGGLRGKGLKTKLTLPVNL
LRACWQSLGALRRVRPDVVLGMGGYITFPAGVMTALSGRPLVLHEQNSIAGLTNKVLAKLAKRVLVAFPGALPHAEWTGN
PIRAELAHTEPPHARYASRSGPLNVLVVGGSLGAAALNEVVPRALALLAPGERPRVVHQAGVKHIEALKANYEAAGFAAG
EDVRLVPFIDDMAAAYAAADLVICRSGAMTVSEIAAVGVAALFVPFPYAVDDHQTTNAAFLAEAGAAVLVQQRDLSAELL
ADWLRGQSRASLADMAERSRALAKPEATDEVARVCAKAAGANLETLQ
>Mature_366_residues
TASQRTLMVMAGGTGGHVFPGLAVAHRMEAAGWRVVWLGNPAGMEATLVPKHGIPMEYVRFGGLRGKGLKTKLTLPVNLL
RACWQSLGALRRVRPDVVLGMGGYITFPAGVMTALSGRPLVLHEQNSIAGLTNKVLAKLAKRVLVAFPGALPHAEWTGNP
IRAELAHTEPPHARYASRSGPLNVLVVGGSLGAAALNEVVPRALALLAPGERPRVVHQAGVKHIEALKANYEAAGFAAGE
DVRLVPFIDDMAAAYAAADLVICRSGAMTVSEIAAVGVAALFVPFPYAVDDHQTTNAAFLAEAGAAVLVQQRDLSAELLA
DWLRGQSRASLADMAERSRALAKPEATDEVARVCAKAAGANLETLQ

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) [H]

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786278, Length=361, Percent_Identity=50.6925207756233, Blast_Score=335, Evalue=2e-93,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235 [H]

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28 [H]

EC number: =2.4.1.227 [H]

Molecular weight: Translated: 38522; Mature: 38391

Theoretical pI: Translated: 9.64; Mature: 9.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTASQRTLMVMAGGTGGHVFPGLAVAHRMEAAGWRVVWLGNPAGMEATLVPKHGIPMEYV
CCCCCEEEEEEECCCCCCCCCHHHHHHHHHHCCEEEEEECCCCCCEEEEECCCCCCHHHH
RFGGLRGKGLKTKLTLPVNLLRACWQSLGALRRVRPDVVLGMGGYITFPAGVMTALSGRP
HHCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCEEEECCCCEECCHHHHHHCCCCE
LVLHEQNSIAGLTNKVLAKLAKRVLVAFPGALPHAEWTGNPIRAELAHTEPPHARYASRS
EEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCHHHCCCC
GPLNVLVVGGSLGAAALNEVVPRALALLAPGERPRVVHQAGVKHIEALKANYEAAGFAAG
CCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCC
EDVRLVPFIDDMAAAYAAADLVICRSGAMTVSEIAAVGVAALFVPFPYAVDDHQTTNAAF
CCEEEEECHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHH
LAEAGAAVLVQQRDLSAELLADWLRGQSRASLADMAERSRALAKPEATDEVARVCAKAAG
HHHCCCEEEEECCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHC
ANLETLQ
CCCCCCC
>Mature Secondary Structure 
TASQRTLMVMAGGTGGHVFPGLAVAHRMEAAGWRVVWLGNPAGMEATLVPKHGIPMEYV
CCCCEEEEEEECCCCCCCCCHHHHHHHHHHCCEEEEEECCCCCCEEEEECCCCCCHHHH
RFGGLRGKGLKTKLTLPVNLLRACWQSLGALRRVRPDVVLGMGGYITFPAGVMTALSGRP
HHCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCEEEECCCCEECCHHHHHHCCCCE
LVLHEQNSIAGLTNKVLAKLAKRVLVAFPGALPHAEWTGNPIRAELAHTEPPHARYASRS
EEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCHHHCCCC
GPLNVLVVGGSLGAAALNEVVPRALALLAPGERPRVVHQAGVKHIEALKANYEAAGFAAG
CCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCC
EDVRLVPFIDDMAAAYAAADLVICRSGAMTVSEIAAVGVAALFVPFPYAVDDHQTTNAAF
CCEEEEECHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHH
LAEAGAAVLVQQRDLSAELLADWLRGQSRASLADMAERSRALAKPEATDEVARVCAKAAG
HHHCCCEEEEECCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHC
ANLETLQ
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA