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The map label for this gene is mraW [H]

Identifier: 116688575

GI number: 116688575

Start: 619286

End: 620227

Strand: Direct

Name: mraW [H]

Synonym: Bcen2424_0551

Alternate gene names: 116688575

Gene position: 619286-620227 (Clockwise)

Preceding gene: 116688574

Following gene: 116688576

Centisome position: 17.78

GC content: 65.39

Gene sequence:

>942_bases
ATGGGAAATGAATTGCGGCATCGGACGGTGCTGTTGGATGAAGCGGTCGAGTCGCTCGTGACGCGGCCGGACGGCGTGTA
CGTCGACGGCACGTTCGGGCGCGGCGGCCACAGCCGCGCGGTGCTCGCGCGGCTGGCGTCGGCCGGGCGGCTGATCGCGT
TCGACAAGGATCCGAGGGCGATCGAGACGGCGCAGGGCATCGAGGATGCGCGCTTCTCGATCGTGCATGACAGCTTTGCA
TCGATGCGCGACGCGCTTGCGGCGCGCGGCGTCGAGAAGGTGTCGGGGGTGTTGCTGGACCTGGGCGTGTCCTCGCCGCA
GGTGGACGATCCGGCGCGCGGCTTCAGTTTCCGCGCCGATGGTCCGCTGGACATGCGAATGGATCCGACGCGTGGCGAGT
CGGCGGCCGAATGGCTCGCGCGGGCTTCGGTGCAGGAATTGACGGAGGTGATACGGGATTATGGGGAAGAACGGTTTGCT
TTTCAGATTGCAAAGGCGCTTGTTGCTCGCCGGGCAGAGTCCGACCGTCTTGGGCCTCTCGACACCACGGGCGAGCTTGC
CCAAATCGTGGGTCACGTCGTCAAAACCCGTGAGAAGGGCAAGGATCCGGCAACCCGCACCTTTCAGGCTATACGGATTC
ACGTCAATCAAGAGCTTGCGGACCTGCAAGTCGTACTAGACGCGGCACTGTCGTTGCTGGAGCAAGGGGGGCGGCTGGTG
GTCATCAGCTTTCATTCACTCGAGGACCGGATCGTCAAGCGATTCATGCAGGCGCACGCGAGTGCGCCTGCGGTCGATCG
TCGCCTGCCGATCCGCGCCGTCGATCTCCCGAGCCCGCCGCTCAAGATCATCAGCCGCCAGTTTCCGAGCGAAGCGGAAG
TCGCCGCGAATCCGCGCGCCCGCTCGGCCGTGATGCGCATCGCGGAGCGCGTCACGCCATGA

Upstream 100 bases:

>100_bases
CGCAGACCTACAACGCGAAGGAGCAGGCAGCGATGGCGCAGGGCATGCCCGACGCGCTGAAGAATTTCACGTTCTGATTG
CGGTGACGGAGACGCCCGCG

Downstream 100 bases:

>100_bases
GCCGCCTCAATATCTTCCTGCTGATCATCGTGATGGGTTGCGCGCTGTCGGTCGTCAACTCGACGAACCAGCAACGCCAG
ATCTTCATCCAGCTGCAGCG

Product: S-adenosyl-methyltransferase MraW

Products: NA

Alternate protein names: 16S rRNA m(4)C1402 methyltransferase; rRNA (cytosine-N(4)-)-methyltransferase RsmH [H]

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MGNELRHRTVLLDEAVESLVTRPDGVYVDGTFGRGGHSRAVLARLASAGRLIAFDKDPRAIETAQGIEDARFSIVHDSFA
SMRDALAARGVEKVSGVLLDLGVSSPQVDDPARGFSFRADGPLDMRMDPTRGESAAEWLARASVQELTEVIRDYGEERFA
FQIAKALVARRAESDRLGPLDTTGELAQIVGHVVKTREKGKDPATRTFQAIRIHVNQELADLQVVLDAALSLLEQGGRLV
VISFHSLEDRIVKRFMQAHASAPAVDRRLPIRAVDLPSPPLKIISRQFPSEAEVAANPRARSAVMRIAERVTP

Sequences:

>Translated_313_residues
MGNELRHRTVLLDEAVESLVTRPDGVYVDGTFGRGGHSRAVLARLASAGRLIAFDKDPRAIETAQGIEDARFSIVHDSFA
SMRDALAARGVEKVSGVLLDLGVSSPQVDDPARGFSFRADGPLDMRMDPTRGESAAEWLARASVQELTEVIRDYGEERFA
FQIAKALVARRAESDRLGPLDTTGELAQIVGHVVKTREKGKDPATRTFQAIRIHVNQELADLQVVLDAALSLLEQGGRLV
VISFHSLEDRIVKRFMQAHASAPAVDRRLPIRAVDLPSPPLKIISRQFPSEAEVAANPRARSAVMRIAERVTP
>Mature_312_residues
GNELRHRTVLLDEAVESLVTRPDGVYVDGTFGRGGHSRAVLARLASAGRLIAFDKDPRAIETAQGIEDARFSIVHDSFAS
MRDALAARGVEKVSGVLLDLGVSSPQVDDPARGFSFRADGPLDMRMDPTRGESAAEWLARASVQELTEVIRDYGEERFAF
QIAKALVARRAESDRLGPLDTTGELAQIVGHVVKTREKGKDPATRTFQAIRIHVNQELADLQVVLDAALSLLEQGGRLVV
ISFHSLEDRIVKRFMQAHASAPAVDRRLPIRAVDLPSPPLKIISRQFPSEAEVAANPRARSAVMRIAERVTP

Specific function: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA [H]

COG id: COG0275

COG function: function code M; Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmH family [H]

Homologues:

Organism=Homo sapiens, GI165377209, Length=338, Percent_Identity=36.9822485207101, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI165377202, Length=198, Percent_Identity=37.8787878787879, Blast_Score=115, Evalue=6e-26,
Organism=Escherichia coli, GI1786270, Length=316, Percent_Identity=53.4810126582278, Blast_Score=330, Evalue=1e-91,
Organism=Drosophila melanogaster, GI62472493, Length=335, Percent_Identity=37.3134328358209, Blast_Score=176, Evalue=2e-44,
Organism=Drosophila melanogaster, GI28571637, Length=335, Percent_Identity=37.3134328358209, Blast_Score=176, Evalue=2e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002903 [H]

Pfam domain/function: PF01795 Methyltransf_5 [H]

EC number: NA

Molecular weight: Translated: 34208; Mature: 34077

Theoretical pI: Translated: 7.27; Mature: 7.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGNELRHRTVLLDEAVESLVTRPDGVYVDGTFGRGGHSRAVLARLASAGRLIAFDKDPRA
CCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHCCCEEEECCCCCH
IETAQGIEDARFSIVHDSFASMRDALAARGVEKVSGVLLDLGVSSPQVDDPARGFSFRAD
HHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
GPLDMRMDPTRGESAAEWLARASVQELTEVIRDYGEERFAFQIAKALVARRAESDRLGPL
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCCC
DTTGELAQIVGHVVKTREKGKDPATRTFQAIRIHVNQELADLQVVLDAALSLLEQGGRLV
CCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHEECCHHHHHHHHHHHHHHHHHHCCCCEE
VISFHSLEDRIVKRFMQAHASAPAVDRRLPIRAVDLPSPPLKIISRQFPSEAEVAANPRA
EEECCCHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCHHHHHHHHCCCCCHHHCCCHH
RSAVMRIAERVTP
HHHHHHHHHHCCC
>Mature Secondary Structure 
GNELRHRTVLLDEAVESLVTRPDGVYVDGTFGRGGHSRAVLARLASAGRLIAFDKDPRA
CCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHCCCEEEECCCCCH
IETAQGIEDARFSIVHDSFASMRDALAARGVEKVSGVLLDLGVSSPQVDDPARGFSFRAD
HHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
GPLDMRMDPTRGESAAEWLARASVQELTEVIRDYGEERFAFQIAKALVARRAESDRLGPL
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCCC
DTTGELAQIVGHVVKTREKGKDPATRTFQAIRIHVNQELADLQVVLDAALSLLEQGGRLV
CCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHEECCHHHHHHHHHHHHHHHHHHCCCCEE
VISFHSLEDRIVKRFMQAHASAPAVDRRLPIRAVDLPSPPLKIISRQFPSEAEVAANPRA
EEECCCHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCHHHHHHHHCCCCCHHHCCCHH
RSAVMRIAERVTP
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA