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The map label for this gene is paaK [H]

Identifier: 116688563

GI number: 116688563

Start: 599333

End: 600631

Strand: Reverse

Name: paaK [H]

Synonym: Bcen2424_0539

Alternate gene names: 116688563

Gene position: 600631-599333 (Counterclockwise)

Preceding gene: 116688564

Following gene: 116688560

Centisome position: 17.24

GC content: 65.82

Gene sequence:

>1299_bases
ATGACTACCCCGCTACCGCTCGAGCCGATCGAGACCGCCTCACGCGACGAGCTGACCGCGCTGCAGCTCGAACGCCTCAA
GTGGTCGCTCCGGCATGCGTATGACCACTCGCCCGTCTATCGCCGCAAGTTCGACGAAGCGGGCGTGCATCCGGATGACG
TGACGACGCTCGCCGACCTGTCGCGCTTCCCGTTCACGACGAAGGGCGATCTGCGCGACAGTTATCCGTTCGGGATGTTC
GCGGTGCCGCAGGACCAGATCTCGCGCATCCATGCGTCGTCCGGCACGACCGGCAAGCCGACGGTCGTCGGCTATACGGC
CGCCGACATCGACACGTGGGCGAATCTCGTCGCACGTTCGATCCGCGCCGCCGGTGCGCGCCGCGGCGACAAGGTGCACG
TCAGCTACGGTTACGGGTTGTTCACGGGCGGGCTCGGCGCGCACTACGGCGCCGAACGCGCGGGCCTCACCGTGATCCCG
TTCGGCGGCGGCCAGACCGAAAAGCAGGTGCAGCTGATCCAGGATTTCCGGCCCGACATCATCATGGTCACGCCGAGCTA
TATGCTGTCGATCGCCGACGAGATCGAGCGCCAGGGCCTCGATCCGGTGCAGAGTTCACTGCGCATCGGCATCTTCGGCG
CGGAGCCGTGGACCAACGACATGCGCGTCGCGATCGAACAGCGGATGGGCATCGATGCGGTCGACATCTACGGGCTGTCC
GAAGTGATGGGCCCGGGCGTGGCGTCCGAATGCGTCGAGACCAAGGATGGCCCGACCATCTGGGAAGACCACTTCTATCC
GGAAATCATCGACCCGGAAACCGGCGAAGTGCTGCCGGACGGCGAACTCGGCGAGCTCGTGTTCACGTCGTTGACGAAGG
AAGCGCTGCCGATCATCCGCTACCGCACCCGTGACCTCACGCGCCTGCTGCCGGGCACCGCCCGGACGATGCGCCGGATG
GAGAAGATCACCGGCCGGTCGGACGACATGATGATCGTGCGCGGCGTCAACGTGTTCCCGACGCAAATCGAGGAACAGTT
GCTCAAGCAGTGCGCGCTCGCGCCGCACTATCAGATCGTGCTGACGAAGGAAGGCCCGCTCGACGTGCTGACGCTCAACG
TCGAGCCCTGCCCGGAAACCGCGCCCGACACCGCGGCGATCCAGGCGGCAAAACAGGCGCTCGCGTACGACATCAAGTCG
CTGATCGGCGTGACGGCCGTGATCAACGTGCTGCCGGTGAACGGCATCGAGCGCTCGGTCGGCAAGGCACGCCGCGTCAT
CGACAAGCGCAAGAGCTGA

Upstream 100 bases:

>100_bases
TCGCGATGTTTCGCGGCAAATCCGCCCAGATCAAGGGCACGGTCATCCCGGAAGACCACTGACGTCGGCGACCCGTCCAT
AACAAACACTGGAGACATGC

Downstream 100 bases:

>100_bases
GGTCACCTCGCCGCGCAGGCGAGCGGCGCGAACTTCGCGCACTCGCCGCACGCACGCCGCGCAGCGGCGAATCCGAGCCT
GCAAATGAAACAGCCCGGTC

Product: phenylacetate-CoA ligase

Products: NA

Alternate protein names: Phenylacetyl-CoA ligase; PA-CoA ligase [H]

Number of amino acids: Translated: 432; Mature: 431

Protein sequence:

>432_residues
MTTPLPLEPIETASRDELTALQLERLKWSLRHAYDHSPVYRRKFDEAGVHPDDVTTLADLSRFPFTTKGDLRDSYPFGMF
AVPQDQISRIHASSGTTGKPTVVGYTAADIDTWANLVARSIRAAGARRGDKVHVSYGYGLFTGGLGAHYGAERAGLTVIP
FGGGQTEKQVQLIQDFRPDIIMVTPSYMLSIADEIERQGLDPVQSSLRIGIFGAEPWTNDMRVAIEQRMGIDAVDIYGLS
EVMGPGVASECVETKDGPTIWEDHFYPEIIDPETGEVLPDGELGELVFTSLTKEALPIIRYRTRDLTRLLPGTARTMRRM
EKITGRSDDMMIVRGVNVFPTQIEEQLLKQCALAPHYQIVLTKEGPLDVLTLNVEPCPETAPDTAAIQAAKQALAYDIKS
LIGVTAVINVLPVNGIERSVGKARRVIDKRKS

Sequences:

>Translated_432_residues
MTTPLPLEPIETASRDELTALQLERLKWSLRHAYDHSPVYRRKFDEAGVHPDDVTTLADLSRFPFTTKGDLRDSYPFGMF
AVPQDQISRIHASSGTTGKPTVVGYTAADIDTWANLVARSIRAAGARRGDKVHVSYGYGLFTGGLGAHYGAERAGLTVIP
FGGGQTEKQVQLIQDFRPDIIMVTPSYMLSIADEIERQGLDPVQSSLRIGIFGAEPWTNDMRVAIEQRMGIDAVDIYGLS
EVMGPGVASECVETKDGPTIWEDHFYPEIIDPETGEVLPDGELGELVFTSLTKEALPIIRYRTRDLTRLLPGTARTMRRM
EKITGRSDDMMIVRGVNVFPTQIEEQLLKQCALAPHYQIVLTKEGPLDVLTLNVEPCPETAPDTAAIQAAKQALAYDIKS
LIGVTAVINVLPVNGIERSVGKARRVIDKRKS
>Mature_431_residues
TTPLPLEPIETASRDELTALQLERLKWSLRHAYDHSPVYRRKFDEAGVHPDDVTTLADLSRFPFTTKGDLRDSYPFGMFA
VPQDQISRIHASSGTTGKPTVVGYTAADIDTWANLVARSIRAAGARRGDKVHVSYGYGLFTGGLGAHYGAERAGLTVIPF
GGGQTEKQVQLIQDFRPDIIMVTPSYMLSIADEIERQGLDPVQSSLRIGIFGAEPWTNDMRVAIEQRMGIDAVDIYGLSE
VMGPGVASECVETKDGPTIWEDHFYPEIIDPETGEVLPDGELGELVFTSLTKEALPIIRYRTRDLTRLLPGTARTMRRME
KITGRSDDMMIVRGVNVFPTQIEEQLLKQCALAPHYQIVLTKEGPLDVLTLNVEPCPETAPDTAAIQAAKQALAYDIKSL
IGVTAVINVLPVNGIERSVGKARRVIDKRKS

Specific function: Catalyzes the activation of phenylacetic acid to phenylacetyl-CoA [H]

COG id: COG1541

COG function: function code H; Coenzyme F390 synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787664, Length=434, Percent_Identity=65.2073732718894, Blast_Score=583, Evalue=1e-168,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000873
- InterPro:   IPR011880 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.30 [H]

Molecular weight: Translated: 47590; Mature: 47459

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTPLPLEPIETASRDELTALQLERLKWSLRHAYDHSPVYRRKFDEAGVHPDDVTTLADL
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHH
SRFPFTTKGDLRDSYPFGMFAVPQDQISRIHASSGTTGKPTVVGYTAADIDTWANLVARS
HHCCCCCCCCCCCCCCCCEEECCHHHHHHHHCCCCCCCCCEEEEEEHHHHHHHHHHHHHH
IRAAGARRGDKVHVSYGYGLFTGGLGAHYGAERAGLTVIPFGGGQTEKQVQLIQDFRPDI
HHHHCCCCCCEEEEEECCCEEECCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCE
IMVTPSYMLSIADEIERQGLDPVQSSLRIGIFGAEPWTNDMRVAIEQRMGIDAVDIYGLS
EEECHHHHHHHHHHHHHCCCCHHHHCCEEEEEECCCCCCHHHHHHHHHCCCCHHHHCCHH
EVMGPGVASECVETKDGPTIWEDHFYPEIIDPETGEVLPDGELGELVFTSLTKEALPIIR
HHHCCCHHHHHHCCCCCCCEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
YRTRDLTRLLPGTARTMRRMEKITGRSDDMMIVRGVNVFPTQIEEQLLKQCALAPHYQIV
HHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCEEEE
LTKEGPLDVLTLNVEPCPETAPDTAAIQAAKQALAYDIKSLIGVTAVINVLPVNGIERSV
EECCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
GKARRVIDKRKS
HHHHHHHHHCCC
>Mature Secondary Structure 
TTPLPLEPIETASRDELTALQLERLKWSLRHAYDHSPVYRRKFDEAGVHPDDVTTLADL
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHH
SRFPFTTKGDLRDSYPFGMFAVPQDQISRIHASSGTTGKPTVVGYTAADIDTWANLVARS
HHCCCCCCCCCCCCCCCCEEECCHHHHHHHHCCCCCCCCCEEEEEEHHHHHHHHHHHHHH
IRAAGARRGDKVHVSYGYGLFTGGLGAHYGAERAGLTVIPFGGGQTEKQVQLIQDFRPDI
HHHHCCCCCCEEEEEECCCEEECCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCE
IMVTPSYMLSIADEIERQGLDPVQSSLRIGIFGAEPWTNDMRVAIEQRMGIDAVDIYGLS
EEECHHHHHHHHHHHHHCCCCHHHHCCEEEEEECCCCCCHHHHHHHHHCCCCHHHHCCHH
EVMGPGVASECVETKDGPTIWEDHFYPEIIDPETGEVLPDGELGELVFTSLTKEALPIIR
HHHCCCHHHHHHCCCCCCCEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
YRTRDLTRLLPGTARTMRRMEKITGRSDDMMIVRGVNVFPTQIEEQLLKQCALAPHYQIV
HHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCEEEE
LTKEGPLDVLTLNVEPCPETAPDTAAIQAAKQALAYDIKSLIGVTAVINVLPVNGIERSV
EECCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
GKARRVIDKRKS
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9748275; 9278503; 10766858 [H]