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The map label for this gene is ttdR [H]

Identifier: 116688515

GI number: 116688515

Start: 549637

End: 550557

Strand: Direct

Name: ttdR [H]

Synonym: Bcen2424_0491

Alternate gene names: 116688515

Gene position: 549637-550557 (Clockwise)

Preceding gene: 116688512

Following gene: 116688518

Centisome position: 15.78

GC content: 73.62

Gene sequence:

>921_bases
ATGGACGACTTCCTTTCCCCGCATCTCGCGCTGTTCGTCGACGTGGTCGACCAGCAGAGCTTCTCGGCGGCCGCGCGCCG
GCTCGGCGTTGCCGCGTCGTCGGTCACGCGGCGCATCGACCGGCTCGAGACGCAGCTCGGCATCCGTCTCCTGCATCGCA
CCACGCACGCGCTGCGGCCGACCGAGGCCGGGCAACTGCTGTACGGGCGCGCGACCCGGATGCTGGCTGAGCTGCGCGGC
TTGCAGGAAGACCTGCACAGCCAGCACGATGAACCGGGCGGGCTGCTGCGTGTCGACTGTCCGGCGCCCTTCGGACGGCG
GCACCTGATGGCCGCGCTGGCCGCGTTCATGCAGCGCTATCCGGCGCTGCAGGTCGACCTCGTGCTGACCGACAGCATGG
TCGACCTGCAGGGCGCGCGGCTCGGCTCCGACGTCGATCTCGCGGTGCGCATCGGCCCGCTCGAGGACACGCGTTTCGTC
GCGACGGTGCTGGCGCCGCAGCGGCGCGTGCTGTGCGCGAGCGCGGCCTATCTCGCACGGTGCGGGGAGCCCGCATCGCC
CGACGCGCTCGGCGGCCACGACTGTCTCGCGTGGCATGGCGCGCCGCCGCCCGGCGCGTGGCGCTTCGGCGAGCGCCGTC
ACGTGCCGGCGCAACCGCGGTTTCGCAGCAATCATTCGGAAGCGTTGCTCGAGGCGGCCATCGACGGGCTCGGTCTCGCG
CACCTGCCGACCTGGCTCGTGGCGGACGCGCTGCGCGACGGACGGTTGCGCGCGCTGCTGCCGCAGTACGCGGCGGCGCC
CGAGCCGGCGACGATTCACGTGCTGCGCCAGCACGCGCGCGGCAGTGCGCGCACGTCGCGGCTCGTCGCGTTCCTCGCCA
CGTGGTTCGCGCAGCCGGCGTGGGACGCCGCGTGGGCGTGA

Upstream 100 bases:

>100_bases
CCGGTGAATGCAGTCTAGTGGGCCCGGTTTGACGCGGAAACGTGCAAAGGCGGATGATTGCTTTGCGTTTTCCGCATAGC
CAAAAATCGCAGGCTCACGA

Downstream 100 bases:

>100_bases
CGGCGGGCGCACGCCGCGCCCCATGAAAAAGGGCCTCGCATGCGAGGCCCGTCAACAGGTCGGAGAAACCGGTACGCCGG
CCGGCGCCGCGGGTCGCGCG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MDDFLSPHLALFVDVVDQQSFSAAARRLGVAASSVTRRIDRLETQLGIRLLHRTTHALRPTEAGQLLYGRATRMLAELRG
LQEDLHSQHDEPGGLLRVDCPAPFGRRHLMAALAAFMQRYPALQVDLVLTDSMVDLQGARLGSDVDLAVRIGPLEDTRFV
ATVLAPQRRVLCASAAYLARCGEPASPDALGGHDCLAWHGAPPPGAWRFGERRHVPAQPRFRSNHSEALLEAAIDGLGLA
HLPTWLVADALRDGRLRALLPQYAAAPEPATIHVLRQHARGSARTSRLVAFLATWFAQPAWDAAWA

Sequences:

>Translated_306_residues
MDDFLSPHLALFVDVVDQQSFSAAARRLGVAASSVTRRIDRLETQLGIRLLHRTTHALRPTEAGQLLYGRATRMLAELRG
LQEDLHSQHDEPGGLLRVDCPAPFGRRHLMAALAAFMQRYPALQVDLVLTDSMVDLQGARLGSDVDLAVRIGPLEDTRFV
ATVLAPQRRVLCASAAYLARCGEPASPDALGGHDCLAWHGAPPPGAWRFGERRHVPAQPRFRSNHSEALLEAAIDGLGLA
HLPTWLVADALRDGRLRALLPQYAAAPEPATIHVLRQHARGSARTSRLVAFLATWFAQPAWDAAWA
>Mature_306_residues
MDDFLSPHLALFVDVVDQQSFSAAARRLGVAASSVTRRIDRLETQLGIRLLHRTTHALRPTEAGQLLYGRATRMLAELRG
LQEDLHSQHDEPGGLLRVDCPAPFGRRHLMAALAAFMQRYPALQVDLVLTDSMVDLQGARLGSDVDLAVRIGPLEDTRFV
ATVLAPQRRVLCASAAYLARCGEPASPDALGGHDCLAWHGAPPPGAWRFGERRHVPAQPRFRSNHSEALLEAAIDGLGLA
HLPTWLVADALRDGRLRALLPQYAAAPEPATIHVLRQHARGSARTSRLVAFLATWFAQPAWDAAWA

Specific function: Positive regulator required for L-tartrate-dependent anaerobic growth on glycerol. Induces expression of the ttdA-ttdB- ygjE operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789440, Length=298, Percent_Identity=32.8859060402685, Blast_Score=157, Evalue=7e-40,
Organism=Escherichia coli, GI1789639, Length=270, Percent_Identity=31.4814814814815, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1786401, Length=257, Percent_Identity=32.295719844358, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI87081978, Length=294, Percent_Identity=31.2925170068027, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI145693193, Length=296, Percent_Identity=33.445945945946, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1787128, Length=268, Percent_Identity=29.4776119402985, Blast_Score=121, Evalue=6e-29,
Organism=Escherichia coli, GI1787589, Length=284, Percent_Identity=29.2253521126761, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1788481, Length=300, Percent_Identity=26.6666666666667, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI1787601, Length=164, Percent_Identity=25, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1788706, Length=248, Percent_Identity=25.8064516129032, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1789173, Length=248, Percent_Identity=28.2258064516129, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33453; Mature: 33453

Theoretical pI: Translated: 8.38; Mature: 8.38

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDDFLSPHLALFVDVVDQQSFSAAARRLGVAASSVTRRIDRLETQLGIRLLHRTTHALRP
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TEAGQLLYGRATRMLAELRGLQEDLHSQHDEPGGLLRVDCPAPFGRRHLMAALAAFMQRY
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHC
PALQVDLVLTDSMVDLQGARLGSDVDLAVRIGPLEDTRFVATVLAPQRRVLCASAAYLAR
CCEEEEEEEECCHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHCCCHHHHHHHHHHHHH
CGEPASPDALGGHDCLAWHGAPPPGAWRFGERRHVPAQPRFRSNHSEALLEAAIDGLGLA
CCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHH
HLPTWLVADALRDGRLRALLPQYAAAPEPATIHVLRQHARGSARTSRLVAFLATWFAQPA
HHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCC
WDAAWA
CCCCCC
>Mature Secondary Structure
MDDFLSPHLALFVDVVDQQSFSAAARRLGVAASSVTRRIDRLETQLGIRLLHRTTHALRP
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TEAGQLLYGRATRMLAELRGLQEDLHSQHDEPGGLLRVDCPAPFGRRHLMAALAAFMQRY
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHC
PALQVDLVLTDSMVDLQGARLGSDVDLAVRIGPLEDTRFVATVLAPQRRVLCASAAYLAR
CCEEEEEEEECCHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHCCCHHHHHHHHHHHHH
CGEPASPDALGGHDCLAWHGAPPPGAWRFGERRHVPAQPRFRSNHSEALLEAAIDGLGLA
CCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHH
HLPTWLVADALRDGRLRALLPQYAAAPEPATIHVLRQHARGSARTSRLVAFLATWFAQPA
HHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCC
WDAAWA
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]