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The map label for this gene is fusA1 [H]

Identifier: 116688369

GI number: 116688369

Start: 401668

End: 403770

Strand: Direct

Name: fusA1 [H]

Synonym: Bcen2424_0345

Alternate gene names: 116688369

Gene position: 401668-403770 (Clockwise)

Preceding gene: 116688368

Following gene: 116688370

Centisome position: 11.53

GC content: 60.87

Gene sequence:

>2103_bases
GTGGCTCGCAAGACTCCTATCGAGCGCTACCGCAATATCGGTATTAGCGCTCACATCGACGCCGGCAAAACGACGACGAC
CGAGCGCATTCTGTTTTACACCGGTGTGAACCACAAGATCGGTGAAGTCCACGACGGCGCAGCCACGATGGACTGGATGG
AGCAGGAACAAGAGCGTGGCATCACGATCACGTCCGCTGCTACCACGGCCTTCTGGAAGGGCATGGGCGGCAACTATCCG
GAACACCGCATCAACATCATCGACACCCCGGGCCACGTCGACTTCACGATCGAAGTGGAACGCTCGATGCGCGTGCTCGA
CGGCGCGTGCATGGTGTACTGCGCAGTGGGCGGCGTGCAGCCGCAGTCGGAAACGGTGTGGCGCCAGGCGAACAAGTACA
AGGTGCCGCGTCTCGCGTTCGTCAACAAGATGGACCGTACCGGCGCGAACTTCTTCAAGGTCTACGACCAGCTCCGTCTG
CGCCTGAAGGCGAACCCGGTTCCGGTCGTGGTGCCGATCGGCGCGGAAGAAAACTTCAAGGGCGTCGTCGACCTGATCAA
GATGAAGGCGATCATTTGGGACGAAGCGTCGCAAGGCACGAAGTTCGACTACGTCGACATCCCGGCCGAGCTCGCGGAGA
CCTGCAAGGAATGGCGCGAAAAGATGGTCGAAGTGGCTGCTGAAGCCAGCGAAGACCTGATGAACAAGTACCTGGAAGAA
GGCGATCTGCCGGAAGCCGACATCGTCAAGGCGCTGCGTGATCGTACGATCGCGTGCGAAATCCAGCCGATGCTGTGCGG
TACCGCGTTCAAGAACAAGGGCGTGCAGCGCATGCTCGACGCCGTGATCGATTTCCTGCCGTCGCCGGTCGACATCCCGC
CGGTCAAGGGCGAACTCGAAAACGGCGAAGAAGCGGAGCGCAAGGCGTCGGACGAAGAGAAGTTCTCGTCGCTCGCGTTC
AAGATCATGACCGACCCGTTCGTCGGCCAGCTGATCTTCTTCCGTGTGTACTCGGGCGTCGTCAACTCGGGCGACACGCT
GCTGAACTCGACCAAGGGCAAGAAGGAACGCCTCGGCCGTATTCTGCAGATGCACGCGAACCAGCGTGAAGAAATCAAGG
AAGTCCGTGCGGGCGACATCGCCGCAGCGGTCGGCCTGAAGGAAGCAACCACGGGCGACACGCTGTGCGACCCGGCGAAC
CCGATCGTTCTTGAACGCATGGTGTTCCCGGAGCCGGTGATTTCGCAGGCAGTCGAGCCGAAGACCAAGGCTGACCAGGA
AAAGATGGGCCTCGCACTGAACCGTCTGGCTCAGGAAGACCCGTCGTTCCGCGTGCAGACCGACGAAGAGTCGGGCCAGA
CCATCATTTCGGGCATGGGCGAGCTCCACCTCGAAATTCTGGTCGACCGGATGAAGCGTGAGTTCGGCGTGGAAGCGACC
GTCGGCAAGCCGCAGGTTGCGTACCGCGAAACGATCCGTTCGACGGCGAAGGATGTCGACGGCAAGTTCGTCAAGCAGTC
GGGTGGTCGCGGCCAGTACGGTCACGCGGTCATCACGCTCGAGCCGAACGAACAAGGCAAGGGCTACGAGTTCTTCGACG
AGATCAAGGGTGGTGTGATTCCGCGTGAATACATCCCGGCGGTCGACAAGGGTATCCAGGACACGCTGAAGTCGGGCGTG
CTGGCTGGCTTCCCGGTCGTCGACGTGAAGGTTCACCTGACGTTCGGTTCGTACCACGACGTTGACTCGAACGAAAACGC
GTTCCGCATGGCCGGTTCGATGGCGTTCAAGGAAGCGATGCGCAAGGCGAACCCGGTCGTCCTCGAGCCGATGATGGCTG
TCGAAGTCGAGACGCCGGAAGACTACATGGGCAACGTGATGGGCGACCTGTCGGGCCGTCGCGGCATCGTCCAGGGCATG
GAAGACATGGTTGGCGGCGGCAAGATCGTGCGCGCCGAAGTGCCGCTGTCGGAAATGTTCGGTTACTCGACGTCGCTGCG
TTCGCTGACGCAAGGTCGTGCAACGTACACGATGGAGTTCAAGCACTACGCTGAAGCTCCGCGCAACGTTGCTGAAGCGA
TCATCAGCGCGAAGTCGAAGTAA

Upstream 100 bases:

>100_bases
AAATAAATTCCGGGCGGGTGCGCTTTTCAGGCGCCTCGCCCGTTTGTGTTGAGGCGTGATGCAGCAGGGCTGCATCACGT
CATCCCAGTAGAGGATCAAA

Downstream 100 bases:

>100_bases
ATCTGTAGCTACCCACCGATAATTTTTGAAAGAAGAGAATCATGGCAAAAGGTAAATTTGAGCGGACCAAGCCGCACGTG
AACGTTGGTACGATTGGTCA

Product: elongation factor G

Products: NA

Alternate protein names: EF-G 1 [H]

Number of amino acids: Translated: 700; Mature: 699

Protein sequence:

>700_residues
MARKTPIERYRNIGISAHIDAGKTTTTERILFYTGVNHKIGEVHDGAATMDWMEQEQERGITITSAATTAFWKGMGGNYP
EHRINIIDTPGHVDFTIEVERSMRVLDGACMVYCAVGGVQPQSETVWRQANKYKVPRLAFVNKMDRTGANFFKVYDQLRL
RLKANPVPVVVPIGAEENFKGVVDLIKMKAIIWDEASQGTKFDYVDIPAELAETCKEWREKMVEVAAEASEDLMNKYLEE
GDLPEADIVKALRDRTIACEIQPMLCGTAFKNKGVQRMLDAVIDFLPSPVDIPPVKGELENGEEAERKASDEEKFSSLAF
KIMTDPFVGQLIFFRVYSGVVNSGDTLLNSTKGKKERLGRILQMHANQREEIKEVRAGDIAAAVGLKEATTGDTLCDPAN
PIVLERMVFPEPVISQAVEPKTKADQEKMGLALNRLAQEDPSFRVQTDEESGQTIISGMGELHLEILVDRMKREFGVEAT
VGKPQVAYRETIRSTAKDVDGKFVKQSGGRGQYGHAVITLEPNEQGKGYEFFDEIKGGVIPREYIPAVDKGIQDTLKSGV
LAGFPVVDVKVHLTFGSYHDVDSNENAFRMAGSMAFKEAMRKANPVVLEPMMAVEVETPEDYMGNVMGDLSGRRGIVQGM
EDMVGGGKIVRAEVPLSEMFGYSTSLRSLTQGRATYTMEFKHYAEAPRNVAEAIISAKSK

Sequences:

>Translated_700_residues
MARKTPIERYRNIGISAHIDAGKTTTTERILFYTGVNHKIGEVHDGAATMDWMEQEQERGITITSAATTAFWKGMGGNYP
EHRINIIDTPGHVDFTIEVERSMRVLDGACMVYCAVGGVQPQSETVWRQANKYKVPRLAFVNKMDRTGANFFKVYDQLRL
RLKANPVPVVVPIGAEENFKGVVDLIKMKAIIWDEASQGTKFDYVDIPAELAETCKEWREKMVEVAAEASEDLMNKYLEE
GDLPEADIVKALRDRTIACEIQPMLCGTAFKNKGVQRMLDAVIDFLPSPVDIPPVKGELENGEEAERKASDEEKFSSLAF
KIMTDPFVGQLIFFRVYSGVVNSGDTLLNSTKGKKERLGRILQMHANQREEIKEVRAGDIAAAVGLKEATTGDTLCDPAN
PIVLERMVFPEPVISQAVEPKTKADQEKMGLALNRLAQEDPSFRVQTDEESGQTIISGMGELHLEILVDRMKREFGVEAT
VGKPQVAYRETIRSTAKDVDGKFVKQSGGRGQYGHAVITLEPNEQGKGYEFFDEIKGGVIPREYIPAVDKGIQDTLKSGV
LAGFPVVDVKVHLTFGSYHDVDSNENAFRMAGSMAFKEAMRKANPVVLEPMMAVEVETPEDYMGNVMGDLSGRRGIVQGM
EDMVGGGKIVRAEVPLSEMFGYSTSLRSLTQGRATYTMEFKHYAEAPRNVAEAIISAKSK
>Mature_699_residues
ARKTPIERYRNIGISAHIDAGKTTTTERILFYTGVNHKIGEVHDGAATMDWMEQEQERGITITSAATTAFWKGMGGNYPE
HRINIIDTPGHVDFTIEVERSMRVLDGACMVYCAVGGVQPQSETVWRQANKYKVPRLAFVNKMDRTGANFFKVYDQLRLR
LKANPVPVVVPIGAEENFKGVVDLIKMKAIIWDEASQGTKFDYVDIPAELAETCKEWREKMVEVAAEASEDLMNKYLEEG
DLPEADIVKALRDRTIACEIQPMLCGTAFKNKGVQRMLDAVIDFLPSPVDIPPVKGELENGEEAERKASDEEKFSSLAFK
IMTDPFVGQLIFFRVYSGVVNSGDTLLNSTKGKKERLGRILQMHANQREEIKEVRAGDIAAAVGLKEATTGDTLCDPANP
IVLERMVFPEPVISQAVEPKTKADQEKMGLALNRLAQEDPSFRVQTDEESGQTIISGMGELHLEILVDRMKREFGVEATV
GKPQVAYRETIRSTAKDVDGKFVKQSGGRGQYGHAVITLEPNEQGKGYEFFDEIKGGVIPREYIPAVDKGIQDTLKSGVL
AGFPVVDVKVHLTFGSYHDVDSNENAFRMAGSMAFKEAMRKANPVVLEPMMAVEVETPEDYMGNVMGDLSGRRGIVQGME
DMVGGGKIVRAEVPLSEMFGYSTSLRSLTQGRATYTMEFKHYAEAPRNVAEAIISAKSK

Specific function: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and

COG id: COG0480

COG function: function code J; Translation elongation factors (GTPases)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily [H]

Homologues:

Organism=Homo sapiens, GI18390331, Length=706, Percent_Identity=44.6175637393768, Blast_Score=560, Evalue=1e-159,
Organism=Homo sapiens, GI19923640, Length=718, Percent_Identity=39.1364902506964, Blast_Score=465, Evalue=1e-131,
Organism=Homo sapiens, GI25306287, Length=718, Percent_Identity=37.1866295264624, Blast_Score=421, Evalue=1e-117,
Organism=Homo sapiens, GI25306283, Length=456, Percent_Identity=41.0087719298246, Blast_Score=308, Evalue=9e-84,
Organism=Homo sapiens, GI4503483, Length=427, Percent_Identity=28.8056206088993, Blast_Score=113, Evalue=6e-25,
Organism=Homo sapiens, GI157426893, Length=153, Percent_Identity=34.640522875817, Blast_Score=99, Evalue=2e-20,
Organism=Homo sapiens, GI94966754, Length=136, Percent_Identity=40.4411764705882, Blast_Score=94, Evalue=6e-19,
Organism=Homo sapiens, GI310132016, Length=120, Percent_Identity=40.8333333333333, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI310110807, Length=120, Percent_Identity=40.8333333333333, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI310123363, Length=120, Percent_Identity=40.8333333333333, Blast_Score=79, Evalue=1e-14,
Organism=Escherichia coli, GI1789738, Length=705, Percent_Identity=74.1843971631206, Blast_Score=1069, Evalue=0.0,
Organism=Escherichia coli, GI1790835, Length=493, Percent_Identity=27.789046653144, Blast_Score=162, Evalue=7e-41,
Organism=Escherichia coli, GI48994988, Length=182, Percent_Identity=37.3626373626374, Blast_Score=106, Evalue=6e-24,
Organism=Escherichia coli, GI1788922, Length=148, Percent_Identity=35.8108108108108, Blast_Score=88, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17533571, Length=691, Percent_Identity=42.5470332850941, Blast_Score=511, Evalue=1e-145,
Organism=Caenorhabditis elegans, GI17556745, Length=718, Percent_Identity=30.7799442896936, Blast_Score=317, Evalue=1e-86,
Organism=Caenorhabditis elegans, GI17506493, Length=427, Percent_Identity=29.9765807962529, Blast_Score=119, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI17557151, Length=209, Percent_Identity=33.0143540669856, Blast_Score=96, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI71988819, Length=146, Percent_Identity=32.1917808219178, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71988811, Length=146, Percent_Identity=32.1917808219178, Blast_Score=74, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6323098, Length=694, Percent_Identity=42.9394812680115, Blast_Score=549, Evalue=1e-157,
Organism=Saccharomyces cerevisiae, GI6322359, Length=806, Percent_Identity=31.7617866004963, Blast_Score=385, Evalue=1e-107,
Organism=Saccharomyces cerevisiae, GI6324707, Length=431, Percent_Identity=27.6102088167053, Blast_Score=102, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6320593, Length=431, Percent_Identity=27.6102088167053, Blast_Score=102, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6323320, Length=157, Percent_Identity=36.3057324840764, Blast_Score=96, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6324166, Length=144, Percent_Identity=37.5, Blast_Score=83, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24582462, Length=711, Percent_Identity=44.8663853727145, Blast_Score=581, Evalue=1e-166,
Organism=Drosophila melanogaster, GI221458488, Length=717, Percent_Identity=31.9386331938633, Blast_Score=352, Evalue=7e-97,
Organism=Drosophila melanogaster, GI24585711, Length=431, Percent_Identity=28.0742459396752, Blast_Score=115, Evalue=7e-26,
Organism=Drosophila melanogaster, GI24585713, Length=431, Percent_Identity=28.0742459396752, Blast_Score=115, Evalue=7e-26,
Organism=Drosophila melanogaster, GI24585709, Length=431, Percent_Identity=28.0742459396752, Blast_Score=115, Evalue=1e-25,
Organism=Drosophila melanogaster, GI78706572, Length=161, Percent_Identity=36.6459627329193, Blast_Score=104, Evalue=2e-22,
Organism=Drosophila melanogaster, GI28574573, Length=143, Percent_Identity=38.4615384615385, Blast_Score=91, Evalue=4e-18,

Paralogues:

None

Copy number: 1080 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 7984 Molecules/Cell In: Growth Phase, Gl

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR000795
- InterPro:   IPR020568
- InterPro:   IPR014721
- InterPro:   IPR005225
- InterPro:   IPR004540
- InterPro:   IPR000640
- InterPro:   IPR005517
- InterPro:   IPR004161
- InterPro:   IPR009000 [H]

Pfam domain/function: PF00679 EFG_C; PF03764 EFG_IV; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: NA

Molecular weight: Translated: 77537; Mature: 77405

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: PS00301 EFACTOR_GTP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARKTPIERYRNIGISAHIDAGKTTTTERILFYTGVNHKIGEVHDGAATMDWMEQEQERG
CCCCCHHHHHHCCCCEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCC
ITITSAATTAFWKGMGGNYPEHRINIIDTPGHVDFTIEVERSMRVLDGACMVYCAVGGVQ
EEEEEHHHHHHHHCCCCCCCCCEEEEEECCCCEEEEEEECHHHHHHHHHHEEHHECCCCC
PQSETVWRQANKYKVPRLAFVNKMDRTGANFFKVYDQLRLRLKANPVPVVVPIGAEENFK
CCHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHEECCCCEEEEECCCCCCHH
GVVDLIKMKAIIWDEASQGTKFDYVDIPAELAETCKEWREKMVEVAAEASEDLMNKYLEE
HHHHHHHHHHHHCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GDLPEADIVKALRDRTIACEIQPMLCGTAFKNKGVQRMLDAVIDFLPSPVDIPPVKGELE
CCCCHHHHHHHHHCCEEEEEEEHHHHCHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCC
NGEEAERKASDEEKFSSLAFKIMTDPFVGQLIFFRVYSGVVNSGDTLLNSTKGKKERLGR
CCHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHCCCCHHHHHHH
ILQMHANQREEIKEVRAGDIAAAVGLKEATTGDTLCDPANPIVLERMVFPEPVISQAVEP
HHHHHCCCHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCCCHHHHHHCCCCHHHHHHCCC
KTKADQEKMGLALNRLAQEDPSFRVQTDEESGQTIISGMGELHLEILVDRMKREFGVEAT
CCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEC
VGKPQVAYRETIRSTAKDVDGKFVKQSGGRGQYGHAVITLEPNEQGKGYEFFDEIKGGVI
CCCCHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCEEEEECCCCCCCCCHHHHHHCCCCC
PREYIPAVDKGIQDTLKSGVLAGFPVVDVKVHLTFGSYHDVDSNENAFRMAGSMAFKEAM
CHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHH
RKANPVVLEPMMAVEVETPEDYMGNVMGDLSGRRGIVQGMEDMVGGGKIVRAEVPLSEMF
HHCCCEEECCEEEEEECCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCEEEEEECCHHHHH
GYSTSLRSLTQGRATYTMEFKHYAEAPRNVAEAIISAKSK
CCHHHHHHHHCCCCEEEEEHHHHHHCHHHHHHHHHHCCCC
>Mature Secondary Structure 
ARKTPIERYRNIGISAHIDAGKTTTTERILFYTGVNHKIGEVHDGAATMDWMEQEQERG
CCCCHHHHHHCCCCEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCC
ITITSAATTAFWKGMGGNYPEHRINIIDTPGHVDFTIEVERSMRVLDGACMVYCAVGGVQ
EEEEEHHHHHHHHCCCCCCCCCEEEEEECCCCEEEEEEECHHHHHHHHHHEEHHECCCCC
PQSETVWRQANKYKVPRLAFVNKMDRTGANFFKVYDQLRLRLKANPVPVVVPIGAEENFK
CCHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHEECCCCEEEEECCCCCCHH
GVVDLIKMKAIIWDEASQGTKFDYVDIPAELAETCKEWREKMVEVAAEASEDLMNKYLEE
HHHHHHHHHHHHCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GDLPEADIVKALRDRTIACEIQPMLCGTAFKNKGVQRMLDAVIDFLPSPVDIPPVKGELE
CCCCHHHHHHHHHCCEEEEEEEHHHHCHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCC
NGEEAERKASDEEKFSSLAFKIMTDPFVGQLIFFRVYSGVVNSGDTLLNSTKGKKERLGR
CCHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHCCCCHHHHHHH
ILQMHANQREEIKEVRAGDIAAAVGLKEATTGDTLCDPANPIVLERMVFPEPVISQAVEP
HHHHHCCCHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCCCHHHHHHCCCCHHHHHHCCC
KTKADQEKMGLALNRLAQEDPSFRVQTDEESGQTIISGMGELHLEILVDRMKREFGVEAT
CCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEC
VGKPQVAYRETIRSTAKDVDGKFVKQSGGRGQYGHAVITLEPNEQGKGYEFFDEIKGGVI
CCCCHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCEEEEECCCCCCCCCHHHHHHCCCCC
PREYIPAVDKGIQDTLKSGVLAGFPVVDVKVHLTFGSYHDVDSNENAFRMAGSMAFKEAM
CHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHH
RKANPVVLEPMMAVEVETPEDYMGNVMGDLSGRRGIVQGMEDMVGGGKIVRAEVPLSEMF
HHCCCEEECCEEEEEECCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCEEEEEECCHHHHH
GYSTSLRSLTQGRATYTMEFKHYAEAPRNVAEAIISAKSK
CCHHHHHHHHCCCCEEEEEHHHHHHCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA